Clinical trials: Ropivacaine
Anesthesia, Spinal, Neurosurgery
Testing the Feasibility of Using Ropivacaine in Spinal Anesthesia for Patients With Lower Back Surgery
The goal of this pilot clinical trial is to test the feasibility of conducting a randomized controlled trial that will examine the use of ropivacaine in the spinal anesthesia for patients undergoing elective 1- or 2-level lower…
- Conditions
- Anesthesia, Spinal, Neurosurgery, Ropivacaine, Bupivacaine
- Trial name
- SASS (NCT05824338)
- Testing
- Spinal anesthesia for lumbar surgery: ropivacaine, Spinal anesthesia for lumbar surgery: bupivacaine, General anesthesia for lumbar surgery
- Where
- 2 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Fraser Health
Postoperative Pulmonary Complications
Using Thoracic Paravertebral Block for Perioperative Lung Preservation During VATS Pulmonary Surgery
Background: Postoperative pulmonary complications (PPCs) may extend the length of stay of patients and even increase perioperative mortality after video-assisted thoracoscopic (VATS) pulmonary surgery.
- Trial name
- NCT05922449
- Testing
- Thoracic Paravertebral Block
- Where
- 2 sites in China
- Volunteers
- 302 people
- Sponsor
- Beijing Tongren Hospital
Hysterectomy, Cystectomy
Erector Spinae Plane Block for Major Gynecologic and Urologic Surgery
Regional anesthesia, also know as a nerve block, is a key component of pain control after major abdominal surgery. Bilateral erector spinae plane block (ESPB) performed at low thoracic level has been shown to be an effective pain…
- Conditions
- Hysterectomy, Cystectomy, Regional Anesthesia
- Trial name
- NCT03500744
- Testing
- Erector spinae plane block
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain, Hip Arthroscopy
PENG Block for Arthroscopic Hip Surgery
This randomized, double-blinded, placebo-controlled trial seeks to evaluate the analgesic efficacy of the pericapsular nerve group block in the setting of outpatient hip arthroscopy.
- Trial name
- PENG (NCT04508504)
- Testing
- Preop PENG block, Ropivacaine 0.5% Injectable Solution, Normal Saline
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Autonomic Nerve Block
Sternotomy PIFB Block in Open Heart Surgery
The purpose of this study is to evaluate if the use of a bilateral nerve block with a local anesthetic (ropivacaine), as part of a standard of care pain control regimen (called multimodal analgesia [MMA]), has a favorable effect…
- Trial name
- NCT06233318
- Testing
- Pecto-intercostal Fascial Block with 20 ml of 0.35% ropivacaine, Pecto-intercostal Fascial Block with normal saline
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- Ohio State University
Thoracic Postherpetic Neuralgia
The Evaluation of Erector Spinae Plane Block for the Pain Control of Thoracic Postherpetic Neuralgia
Erector spinae plane block is new interfascial plane block, and can be applied to management of thoracic neuropathic pain syndromes. The target of needle is deeper(or anterior) to the erector spinae muscle.
- Trial name
- NCT03595046
- Testing
- erector spinae plane block (20 mL of 0.25% ropivacaine with dexamethasone 5mg), thoracic paravertebral block(10 mL 0.25% ropivacaine with dexamethasone 5mg)
- Where
- South Korea
- Sponsor
- Yonsei University
Rotator Cuff Injuries, Shoulder Disease
Feasibility of an Analgesic Device Enabling Local Anesthetic Delivery and Neuromodulation After Shoulder/Foot Surgery
Postoperative pain remains undertreated with inadequate analgesic options. Opioids have well-known limitations for both individuals and society; single-injection and continuous peripheral nerve blocks provide intense analgesia…
- Conditions
- Rotator Cuff Injuries, Shoulder Disease, Hallux Valgus, Ankle Arthropathy
- Trial name
- NCT06818708
- Testing
- Experimental Treatment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Regional Anesthesia, Femoral Nerve Block
Comparison of the Sensitive Cutaneous Block Distribution Following Femoral Nerve Block Using Two Femoral Block Techniques
In this study, we will be comparing two approaches to the femoral block. The first or classical approach and one that is the most popular in our institution is used by combining ultrasound guidance and neurostimulator to do the…
- Trial name
- NCT02721290
- Testing
- Femoral nerve block using Ultrasound and neurostimulator, Femoral nerve block using Ultrasound, Ropivacaine 0.5%
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Maisonneuve-Rosemont Hospital
Healthy Volunteers
Effect of Systemic Ropivacaine on Hyperalgesia, Flare Reaction and Peripheral Nerve Excitability
The purpose of this study is to compare the effect of intravenous ropivacaine and lidocaine on the receptive field of primary sensory afferents and their influence on the vascular bed. *Trial with medicinal product
- Trial name
- NCT00900913
- Testing
- ropivacaine (Naropin)
- Where
- Switzerland
- Volunteers
- 34 people
- Sponsor
- University of Zurich
Postoperative Pain, Acute
Anterior Suprascapular Versus Interscalene Block for Postoperative Analgesia After Arthroscopic Shoulder Surgery in the Outpatient Setting
Shoulder surgery performed in the outpatient setting can be associated with moderate to severe postoperative pain, especially during the first hours after surgery.
- Trial name
- NCT07831096
- Testing
- Interscalene Nerve Block, Anterior suprascapular nerve block, Ropivacaine
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Sette Laghi
Knee Osteoarthritis
Exparel vs Exparel Plus ACB in TKAs
Patients will be randomized (like the flip of a coin) to receive Exparel and a nerve block, standard of care for this procedure, or Exparel alone for pain management after surgery.
- Trial name
- NCT02365727
- Testing
- Liposomal bupivacaine, Ropivacaine, Epinephrine
- Where
- United States
- Sponsor
- The Hawkins Foundation
Postoperative Pain Treatment for Total Knee Arthroplasty
Total Knee Arthroplasty Analgesia: Single-shot Femoral Nerve Block or Epidural?
Single-shot femoral nerve block is similar to continuous epidural technique for postoperative analgesia in total knee arthroplasty
- Trial name
- NCT02164825
- Testing
- Ropivacaine perineural injection, morphine and ropivacaine
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Centro Hospitalar do Tâmega e Sousa
Osteoarthritis, Knee
Postoperative Pain Control After Periarticular Injection During Total Knee Arthroplasty
This study will evaluate the use of a local injection around the knee (periarticular) during total knee replacement (TKR) surgery to see if it reduces postoperative pain levels.
- Trial name
- NCT02570503
- Testing
- Ropivacaine, Ketorolac, Clonidine
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Single-level Lumbar Arthrodesis
Intravenous Lidocaine Versus Erector Spinae Plane Block After Lumbar Arthrodesis (LIBERA)
The hypothesis of this study is that intraoperative intravenous lidocaine infusion provides postoperative analgesia and opioid-sparing effects that are at least equivalent to those achieved with a bilateral erector spinae plane…
- Trial name
- LIBERA (NCT07895368)
- Testing
- Single-level posterior lumbar arthrodesis
- Where
- France
- Volunteers
- 90 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Postoperative Pain
A Preemptive Epidural Ropivacaine for Postoperative Pain Relief in Degenerative Lumbar Spine Surgery
This prospective randomized study aims to evaluate the effectiveness of epidural injection of ropivacaine on the relief of pain in patients undergoing laminectomy.
- Trial name
- NCT01117610
- Testing
- Ropivacaine (epidural injection)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Chung-Ang University Hospital
Wrist Injuries, Postoperative Pain Control
Single Shot Infraclavicular Brachial Plexus Block vs Local Infiltration After Wrist Arthroscopy Surgery
The purpose of this study is to compare infraclavicular brachial plexus shot single shot block to local infiltration done in adult patients having wrist arthroscopy surgery.
- Trial name
- NCT02970097
- Testing
- 20ml bolus of 0.5% ropivicaine, 10 ml of 0.5% ropivicaine, Midazolam
- Where
- United States
- Sponsor
- University of Pennsylvania
Sepsis, Acute Gastrointestinal Injury
Erector Spinae Plane Block Improves Organ Dysfunction in Septic Patients With Acute Gastrointestinal Injury
This study is a prospective, multicenter, parallel-group, open-label, randomized controlled clinical trial. Sepsis is defined as organ dysfunction induced by infections.
- Conditions
- Sepsis, Acute Gastrointestinal Injury, Organ Dysfunction Syndrome
- Trial name
- NCT05623722
- Testing
- Erector spinae plane block
- Where
- China
- Volunteers
- 116 people
- Sponsor
- Jing Cai, MD
Stellate Ganglion Block
The Effect of Stellate Ganglion Block on Postoperative Sleep Disturbance and Cognitive Function in Elderly Surgical Patients
Postoperative delirium is an acute state of confusion, which is characterized by changes in attention and cognitive functions and fluctuations in consciousness; postoperative cognitive dysfunction is a common central nervous…
- Trial name
- NCT04800653
- Testing
- Stellate ganglion block
- Where
- China
- Volunteers
- 48 people
- Sponsor
- Yangzhou University
Postoperative Pain
Perineural Dexamethasone in Femural Nerve Block After Ligament Reconstruction
The effect of perineural dexamethasone administered as an adjuvant in prolonging the duration of analgesia continues to be under debate.
- Trial name
- NCT02749162
- Testing
- Dexamethasone phosphate, Paracetamol, Morphine
- Where
- Romania
- Volunteers
- 90 people
- Sponsor
- Foisor Orthopedics Clinical Hospital
Hip Arthropathy
Periarticular Injection Versus Peripheral Nerve Block in Total Hip Arthroplasty
This study will assess if preoperative quadratus lumborum block (QLB)/lateral femoral cutaneous nerve block (LFCNB) with ropivacaine and glucocorticoids provide more effective analgesia than periarticular injection (PAI) with the…
- Trial name
- NCT03977454
- Testing
- Nerve Block, Periarticular Injection (PAI), Ropivacaine
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Yale University
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