Clinical trials: Ropivacaine
Analgesia, Dexamethasone
Low-dose Intravenous Dexamethasone at Different Times as Adjunvants for Brachial Plexus Blocks
Dexamethasone has been tested as an effective adjuvant to prolong the effect of local anesthetics for peripheral nerve blocks, both perineurally and intravenously.
- Conditions
- Analgesia, Dexamethasone, Brachial Plexus Block, Intravenous Drug Usage
- Trial name
- NCT04714112
- Testing
- dexamethasone
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Shoulder Injury
Ropivacaine Block Alone or With Perineural or Systemic Dexamethasone for Pain in Shoulder Surgery
Pre-operative perineural injection of dexamethasone mixed with local anesthetic in peripheral nerve blockade for orthopedic surgery has been shown to prolong the length of analgesia, improve visual analog pain scores, decrease…
- Trial name
- NCT01450007
- Testing
- Ropivacaine, Dexamethasone, Normal saline
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Mayo Clinic
Gastric Cancer, Postoperative Pain
Comparison of the Postoperative Analgesic Effects of the Temperature-responsive Gel Mixed With Local Anesthetics Application and Ultrasound-guided Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Gastrectomy
This study is a single-center, prospective, randomized controlled trial designed to compare two established postoperative analgesic strategies in adult patients undergoing laparoscopic gastrectomy under general anesthesia.
- Trial name
- TAP-WELPASS (NCT07452471)
- Testing
- Ultrasound-guided Transversus Abdominis Plane (TAP) Block, Ropivacaine-Poloxamer 407 Hydrogel (Welpass®)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Gyeong-Jo Byeon, MD, PhD
Hip Fracture
Peripheral Nerve Blocks in Elderly Patients With Hip Fracture
As the population ages, the frequency of surgery is increasing proportionally, bringing with it the challenge of managing older patients with frequent comorbid diseases and an increased risk of complications.
- Trial name
- NCT02635763
- Testing
- Femoral nerve and the lateral cutaneous nerve block, Lumbar plexus and sacral plexus nerve block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Fibroid Uterus, Pain, Postoperative
Pre-incisional Wound INfiltration and Hypogastric PLEXus Block Using Ropivacaine in Laparoscopic Myomectomy
The purpose of this study is to assess an impact of laparoscopic superior hypogastric plexus (SHP) block combined with preemptive troacar site infiltration on postoperative pain intensity following laparoscopic myomectomy.
- Trial name
- WINPLEX (NCT06429163)
- Testing
- Troacar site infiltration, Superior hypogastric plexus block
- Where
- Russia
- Volunteers
- 207 people
- Sponsor
- Saint Petersburg State University, Russia
Gastrectomy
A Comparison of Dexmedetomidine and Epidural Anesthesia Under General Anesthesia in Patients Undergoing Gastrectomy
Clinically, combining epidural with general anaesthesia may confer many advantages to patients undergoing major thoracic, abdominal or orthopaedic surgery.
- Trial name
- NCT01657812
- Testing
- dexmedetomidine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Anhui Medical University
Rib Fractures, Trauma
Continuous Erector Spinae Plane Blocks for Rib Fractures
Rib fractures are one of the most common injuries in trauma patients. These fractures are associated with significant pain as well as decreased ability to inspire deeply or cough to clear secretions, which together lead to…
- Conditions
- Rib Fractures, Trauma, Anesthesia, Anesthesia, Local
- Trial name
- NCT04558281
- Testing
- Active ropivacaine 0.3% erector spinae plane perineural administration
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of California, San Diego
Headache, Covid19
The Effect of Ganglion Sphenopalatine Block Versus Placebo on Persistent Headache Following COVID-19 Infection
The purpose of this study is to evaluate the effect of the ganglion sphenopalatine block (SPG block) on persistent headache following acute COVID-19 infection.
- Conditions
- Headache, Covid19, Sphenopalatine Ganglion Block, Persistent Headache Following COVID-19
- Trial name
- NCT04636034
- Testing
- Sphenopalatine Ganglion Block with Local Anesthetic
- Where
- Denmark
- Volunteers
- 18 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Lumbosacral Radiculopathy, Lumbar Radiculopathy
Platelet Lysate vs Saline for Lumbosacral Radiculopathy
This is a randomized trial to evaluate and compare platelet lysate epidural injection to saline epidural injection for the treatment of lumbar radiculopathy (sciatica).
- Trial name
- NCT06924853
- Testing
- Platelet lysate, Saline control
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Regenexx, LLC
Frailty, Telomere
A Study of the Correlation Between the Debilitating State of the Elderly and Propofol Sensitivity
In an aging society, there is a surge in the number of surgeries for elderly patients in hospitals, and the elderly are at greater risk of anesthesia due to their own characteristics: slowing metabolism, decreasing resistance…
- Trial name
- NCT06870357
- Testing
- propofol
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Second Hospital of Shanxi Medical University
Radius Fractures, Ulna Fractures
Addition of Dexmedetomidine to Ropivacaine-induced Supraclavicular Block (ADRIB Trial)
Dexmedetomidine, an alpha 2-adrenoreceptor agonist, has been found to exerts an excellent influences on the filed of perineural block.
- Conditions
- Radius Fractures, Ulna Fractures, Hand Injuries, Wrist Injuries
- Trial name
- ADRIB (NCT02630290)
- Testing
- Ropivacaine, Ropivacaine + Dexmedetomidine
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Guangzhou First People's Hospital
Hysterectomy
Transversus Abdominis Plane Block After Robot-assisted Laparocopic Hysterectomy
The purpose of this study is to investigate the effectiveness of Transversus Abdominis Plane (TAP) block as a part of a multimodal postoperative pain management after robot-assisted laparoscopic hysterecomy.
- Trial name
- TAP-block (NCT01504386)
- Testing
- TAP block
- Where
- Denmark
- Volunteers
- 70 people
- Sponsor
- Copenhagen University Hospital at Herlev
Scoliosis Idiopathic
Erector Spinae Plane Block for Pediatric Idiopathic Scoliosis Surgery
The study aims to assess the effect of the interfacial plane blocks on the pain level, the course of postoperative rehabilitation, and its anti-inflammatory analgesic effect.
- Trial name
- ESPB (NCT05938959)
- Testing
- ESPB
- Where
- 2 sites in Poland
- Volunteers
- 100 people
- Sponsor
- Poznan University of Medical Sciences
Breast/Surgery, Postoperative Complication
Serratus Plane Block for the Prevention of Chronic Pain After Breast Cancer Surgery
This study compare the "Serratus block plane" (SPB) and the local infiltration of the tissue in the prevention of acute and chronic pain after breast cancer surgery.
- Conditions
- Breast/Surgery, Postoperative Complication, Chronic Pain
- Trial name
- NCT02838173
- Testing
- serratus plane bloc : Ropivacaine 2mg/ml (0,3ml/kg), tissue infiltration : Ropivacaine 2mg/ml (0,3ml/kg)
- Volunteers
- 110 people
- Sponsor
- Erasme University Hospital
Video Assisted Thoracic Surgery (VATS), Pain Management
QoR40 Between Intercostal Block and Intercostal Block and Serratus Plane Catheter During VATS
Video assisted thoracic surgery (VATS) has emerged as standard of care for majority of thoracic surgeries. It is less invasive compared to thoracotomy and is associated with improved perioperative outcomes [1-3].
- Trial name
- NCT04990713
- Testing
- Serratus Plane Block (Local Anesthetic) and Intercostal Block (Local Anesthetic)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Anesthesia, Regional
The Analgesic Efficacy of the Ultrasound-Guided Femoral Articular Branch Block for Ambulatory Hip Arthroscopy
Hip arthroscopy surgery can be associated with significant pain. A regional anesthesia technique, the femoral articular branch block (FAB), has recently been proposed to collectively block terminal femoral and accessory obturator…
- Trial name
- NCT03449680
- Testing
- Femoral Articular Branch Block
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- Women's College Hospital
Total Hip Arthroplasty, Postoperative Pain
Pericapsular Nerve Group (PENG) Block Combined With Periarticular Multimodal Drug Injection (PMDI) Versus Isolated PMDI for Pain Management After Total Hip Arthroplasty: a Randomized Controlled Trial
Adequate pain control after total hip arthroplasty is crucial for early ambulation and patient satisfaction. However, there is no consensus about optimal pain control after post operation.
- Trial name
- NCT05320913
- Testing
- Pericapsular nerve group(PENG) block combined with periarticular multimodal drug injection (PMDI), isolated periarticular multimodal drug injection (PMDI)
- Where
- South Korea
- Volunteers
- 58 people
- Sponsor
- Yonsei University
Hip Arthropathy, Hip Osteoarthritis
PENG Block Optimization: Volume and Dexamethasone Effects
This randomized controlled trial investigates the impact of local anesthetic volume and perineural dexamethasone on the analgesic and anti-inflammatory effectiveness of the pericapsular nerve group (PENG) block in patients…
- Conditions
- Hip Arthropathy, Hip Osteoarthritis, Hip Arthritis
- Trial name
- NCT07023120
- Testing
- Ropivacaine 0.2% Injectable Solution, Dexamethasone 4mg
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- Poznan University of Medical Sciences
Pain
Multimodal Pain Management Following Primary TKA
The investigators plan to evaluate the length of time to discharge readiness between the groups (continuous femoral nerve blocks (cFNB) vs. liposomal bupivacaine (LB) vs.
- Trial name
- NCT02369523
- Testing
- Exparel, Ropivacaine cocktail (PIC), Bupivacaine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Utah
Pain, Postoperative
Effects of Intra-Operative Ropivaciane Epidural Injection on Post-Operative Outcomes Following Elective Lumbar Fusion
The following is a double blinded, randomized controlled clinical trial to test the hypothesis that a single epidural injection of Ropivaciane® intra operatively will:1) Single intra-operative epidural injection of Ropivaciane®…
- Trial name
- NCT03035656
- Testing
- Ropivacaine, Saline
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Horizon Health Network
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