Clinical trials: Ropivacaine
Arthroplasty, Replacement, Knee, Patient-controlled Analgesia
Postoperative Patient Controlled Epidural Analgesia After Total Knee Arthroplasty With 2ug/ml Fentanyl Combine With 0.2% Ropivacaine or 0.2% Levobupivcaine
Postoperative epidural analgesia (EA) is an effective and well-accepted modality of pain relief technique after having total knee replacement operation(1,4).
- Trial name
- NCT01158586
- Testing
- Levobupivacaine
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- United Christian Hospital
Hand Injury
Retroclavicular Versus Supraclavicular Brachial Plexus Block for Hand and Forearm Surgery
Patients will be randomized to one of two groups: 1. Supraclavicular group: supraclavicular brachial plexus block performed with the aid of ultrasound; 2.
- Trial name
- NCT02641613
- Testing
- retroclavicular block, supraclavicular block
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Hôpital du Valais
Breast Cancer Surgery, ESPB
Onset of Sensory Block After Thoracic ESP Block
The goal of this observational study is to to evaluate the changes in cold sensitivity and the onset of sensory block after performing a thoracic ESP block.
- Trial name
- NCT06642142
- Testing
- ESP block
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Ospedale Santa Maria Goretti
Osteoarthritis, Knee
Efficacy and Safety of Liposomal Bupivacaine Using Periarticular Injection in Total Knee Arthroplasty
The goal of this clinical trial is to learn if drug Bupivacaine liposomes works better than traditional peri-articular injection for Control of Pain in Total Knee Arthroplasty.
- Trial name
- NCT06557018
- Testing
- liposomal bupivacaine, traditional peri-articular injection
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Dezhou Hospital Qilu Hospital of Shandong University
Hip Osteoarthritis
SII Levels Following PENG Block in Hip Arthroplasty
This randomized controlled trial evaluates the effect of ultrasound-guided Pericapsular Nerve Group (PENG) block on the Systemic Immune-Inflammation Index (SII) in elderly patients undergoing total hip arthroplasty under spinal…
- Trial name
- NCT07449403
- Testing
- sodium Chloride, Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Knee Osteoarthritis, Knee Pain Chronic
Two-level ESPB in Total Knee Arthroplasty
Effect of two-level ESPB in Total Knee Arthroplasty
- Conditions
- Knee Osteoarthritis, Knee Pain Chronic, Knee Arthritis
- Trial name
- NCT06470542
- Testing
- 2 x 20 ml of Ropivacaine 0.2% Injectable Solution, 2 x 20ml of Ropivacaine 0.2% Injectable Solution
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Headache, Post-Dural Puncture
Sphenopalatine Blockade Versus Clinical Treatment
Post-dural puncture headache leads to high morbidity and cost to the health system. Pregnant women have a higher incidence than other population groups.
- Trial name
- NCT04148846
- Testing
- Dypirone, Sphenopalatine block, Ketoprofen
- Where
- Brazil
- Volunteers
- 45 people
- Sponsor
- University of Sao Paulo General Hospital
Nerve Block, Pain
Intercostobrachial Nerve Block (ICBN) for Tourniquet Pain: Is it Necessary?
In this study the investigators would like to show that when patients undergo upper limb surgery under supraclavicular brachial plexus block, additional blocking of the Intercostobrachial Nerve Block (ICBN) does not affect the…
- Trial name
- ICBN (NCT03797924)
- Testing
- Receive ICBN with ropivacaine, No ICBN block
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Florida
Total Knee Arthroplasty, Post Operative Analgesia
Comparing Postoperative Functional Recovery and Analgesic Efficacy of a Single Shot Sciatic Nerve Block Versus Posterior Capsule/Fat Pad Infiltration of Local Anesthetic for Total Knee Arthroplasty
Many methods of pain relief have been implemented in an attempt to provide safe and effective analgesia for patients following total knee arthroplasty.
- Trial name
- NCT00677261
- Testing
- Sciatic Nerve Block, Posterior capsule infiltration with local anesthetic
- Where
- Canada
- Volunteers
- 104 people
- Sponsor
- Sunnybrook Health Sciences Centre
Pain After Abdominal Surgery
A Clinical Trial Evaluating the Efficacy and Safety of Local Infiltration of RF16001 for Injection for Analgesia After Total Hip Arthroplasty in China
A multicenter, randomized, double-blind, placebo-positive, parallel-controlled, phase Ⅲ clinical trial was conducted to investigate the efficacy and safety of RF16001 local infiltration for analgesia after total hip arthroplasty.
- Trial name
- NCT07872826
- Testing
- RF16001 for injection, Ropivacaine hydrochloride injection, 0.9% sodium chloride injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Rupture of Anterior Cruciate Ligament, Tear of Anterior Cruciate Ligament
Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction
Despite the apparent multifaceted benefit in differentiating blockade sites and duration of nerve blockade, the efficacy of continuous adductor canal blockade utilized specifically in ACL reconstruction has not been extensively…
- Trial name
- NCT02584452
- Testing
- Mepivacaine, adductor canal continuous nerve catheter, Normal Saline as bolus followed by bupivacaine
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Vanderbilt University Medical Center
Anesthesia, Local, Phrenic Nerve Paralysis
Interscalene Brachial Plexus Block Washout to Reverse Inadvertent Phrenic Nerve Blockade
One of the most frequently performed peripheral nerve blocks (the injection of local anesthetic near nerves to block sensation/ movement to a specific part of the body) is the interscalene brachial plexus block for upper…
- Conditions
- Anesthesia, Local, Phrenic Nerve Paralysis, Upper Extremity Injury, Phrenic Nerve Palsy on the Left
- Trial name
- NCT03677778
- Testing
- Normal saline injected via interscalene nerve catheter
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Stanford University
Pudendal Nerve Block
Ultrasound-guided Pudendal Nerve Block in Children: A Descriptive Study of Feasibility
Objective: Description of a new transperineal technique of pudendal nerve block (PNB), under ultrasound-guidance. Methods : Successive inclusions after parental consent of 60 children undergoing perineal surgery under general…
- Trial name
- NCT02496325
- Testing
- Ultrasound guided transperineal pudendal nerve block
- Where
- France
- Volunteers
- 196 people
- Sponsor
- University Hospital, Montpellier
Hip Osteoarthritis, Hip Arthroplasty Replacement
Post-Operative Spinal Block Duration and Pain Relief After Hip Replacement Surgery: Comparing Single-Shot Spinal Ropivacaine and Bupivacaine
This study aims to determine whether isobaric ropivacaine is more suitable than isobaric bupivacaine for spinal anesthesia in outpatient total hip arthroplasty (THA).
- Conditions
- Hip Osteoarthritis, Hip Arthroplasty Replacement, Postoperative Pain After Ambulatory Surgery
- Trial name
- ROBUTHA (NCT07631091)
- Testing
- Spinal Anesthesia with Ropivacaine 15 mg (5 mg/ml), Spinal Anesthesia with Bupivacaine 11 mg (5 mg/ml)
- Volunteers
- 176 people
- Sponsor
- University of Turku
Regional Anesthesia, Thoracic Surgery
Serratus Anterior Plane Block: Post-operative Analgesia in Video-assisted Thoracic Surgery
The objective of the study is to compare the efficacy of the Serratus Anterior Plane block (SPB) realised in its deep plane, with a multi-holed catheter in place for twenty four hours, to a standard intravenous analgesia for…
- Conditions
- Regional Anesthesia, Thoracic Surgery, Post-operative Pain, Post-operative Chronic Pain
- Trial name
- Serrathos (NCT03277391)
- Testing
- Serratus anterior plane block, patient-controlled analgesia
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Université Libre de Bruxelles
Spondylolisthesis, Lumbar Disc Herniation
Erector Spinae Plane Block as Pain Management After Lumbar Fusion Surgery
Rationale: Lumbar spine surgery is associated with high postoperative pain scores and analgesic use, despite use of multimodal analgesia.
- Conditions
- Spondylolisthesis, Lumbar Disc Herniation, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Trial name
- RCT-ESPB (NCT05345249)
- Testing
- Ropivacaine Hydrochloride Injection, Sodium chloride
- Where
- Netherlands
- Volunteers
- 76 people
- Sponsor
- Ilse van de Wijgert
Hypospadias
The Effect of Caudal Block on the Postoperative Complications in Pediatric Patients After Hypospadias Repair
Hypospadias refers to a disease represented by a congenital defect in the urethra meatus (urinary opening) in male children. Due to the postoperative pain, symptoms such as discomfort, agitation, and restlessness are generally…
- Trial name
- NCT02164682
- Testing
- IV PCA group, IV PCA+ caudal block group
- Where
- South Korea
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Postoperative Pain
Ropivacaine With Clonidine For Pediatric Rectus Sheath Blocks- The Magic Combination
Background: Millions of pediatric patients undergo laparoscopic surgeries every year and many of them suffer significant pain and anxiety.
- Trial name
- NCT02439281
- Testing
- Clonidine, Ropivacaine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mihaela Visoiu
Breast Neoplasms, Breast Neoplasm Female
Thoracic Paravertebral Block Anesthesia for Breast Cancer Surgery
Background: Mastectomies are traditionally performed under general anesthesia (GA), often with the addition of regional anesthesia for post-operative pain relief.
- Conditions
- Breast Neoplasms, Breast Neoplasm Female, Cancer, Breast, Breast Cancer
- Trial name
- TPVB (NCT05711030)
- Testing
- Thoracic paravertebral block multiple (3) injections, Thoracic paravertebral block single injection
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Breast Cancer Surgery, Postoperative Analgesia
Postoperative Analgesia in Breast Cancer Surgery: Safety and Efficiency of Ultrasound Guided Erector Spinae Plane Block
Breast cancer surgery is one of the most common surgeries, due to the high incidence of breast cancer. Unfortunately, patients experience significant postoperative acute pain, placing them at risk for increased clinical morbidity…
- Trial name
- erectspinae (NCT03769428)
- Testing
- erector spinae plane block
- Where
- Tunisia
- Volunteers
- 60 people
- Sponsor
- Ben marzouk Sofiene
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