Clinical trials: Ropivacaine
Paresis
Bupivacaine Versus Ropivacaine on Diaphragmatic Motility and Ventilatory Function
Background: Outpatient continuous interscalene brachial plexus blocks are used to control pain after shoulder surgery, with infusions of 0.125% bupivacaine or 0.2% ropivacaine.
- Trial name
- NCT02059070
- Testing
- Ropivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Anesthesiology WSU/DMC-NorthStar
Pain Postoperative
Analgesic Efficacy of Transmuscular Quadratus Lumborum in Patients Undergoing Total Abdominal Hysterectomy
Patients who have undergone laparotomies often require multimodal postoperative pain regimes. In recent years, abdominal wall blocks have been included to become part of this in order to overcome side effects of systemic opioids…
- Trial name
- NCT02586454
- Testing
- Transmuscular quadratus lumborum block, morphine, ropivacaine
- Where
- Malaysia
- Volunteers
- 64 people
- Sponsor
- Kuala Lumpur General Hospital
Total Knee Arthroplasty
Analgesia After Total Knee Replacement Surgery
Postoperative pain after total knee replacement surgery is difficult to treat. Mobilisation and hospital discharge might be delayed.
- Trial name
- NCT01489631
- Testing
- naropin, marcaine, sufentanil
- Where
- Netherlands
- Volunteers
- 81 people
- Sponsor
- St. Antonius Hospital
Knee Joint Arthritis, Knee Joint Arthroplasty
Motor Sparing Block vs. Peri-Articular Catheters
This study is designed to determine if one anaesthetic modality, either motor sparing nerve block or peri-articular local infiltration anaesthesia with infusion, is superior in providing postoperative analgesia following total…
- Trial name
- NCT01503528
- Testing
- Motor Sparing Nerve Block, Peri-articular Catheters
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Postoperative Pain, Inflammation
Steroids in Total Knee Arthroplasty
The purpose of this study is to evaluate if the use of two small doses of intravenous (IV) steroids around the time of knee replacement surgery decrease a patient's pain or use of pain medication.
- Conditions
- Postoperative Pain, Inflammation, Osteoarthritis
- Trial name
- NCT02219581
- Testing
- Dexamethasone 10 mg, Dexamethasone 20 mg, Standard multimodal pain management regimen
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Thomas L Bradbury
Breast Cancer
Continues Cicatricial Perfusion of Ropivacaine Versus Placebo After Mastectomy : Rehabilitation After Treatment
The acute pain care, in particular after breast cancer surgery must be early and quickly effective, because a severe postoperative pain increases the risk of chronic pain and exposes to a risk of important embarrassment for the…
- Trial name
- NCT02525211
- Testing
- Ropivacaine, physiological saline
- Where
- France
- Volunteers
- 59 people
- Sponsor
- Institut Paoli-Calmettes
Laparoscopic Cholecystectomy, Postoperative Pain
Comparison of ANI Between Preoperative and Postoperative Ultrasound-guided TAP Block in Laparoscopic Cholecystectomy
The goal of this clinical trial is to learn if the timing of ultrasound-guided transversus abdominis plane block (US-TAP block) administration (preoperative vs.
- Trial name
- CholeANI (NCT07809009)
- Testing
- Preoperative US-TAP Block, Postoperative US-TAP Block
- Volunteers
- 120 people
- Sponsor
- Pusan National University Yangsan Hospital
Postoperative Pain
Does ESPB Improve Postoperative Quality of Recovery After VATS
Video-Assisted Thoracoscopic Surgery (VATS) is a minimally invasive surgery. Despite reduced surgical trauma compared to the traditional thoracotomy approach, pain control after VATS remains challenging.
- Trial name
- NCT03756987
- Testing
- Ropivacaine Injection, Normal saline
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Fujian Provincial Hospital
Surgery, Pain
Evaluation of the Interest of the Instillation of Saline Intraperitoneally (INSI ) Versus Instillation of Naropin the Surgical Site Versus Lung Recruitment Maneuvers ( PVM ) in the Management of Pain After Laparoscopic Cholecystectomy in Ambulatory Care
Known to reduce analgesics and length of hospitalization in conventional surgery, laparoscopy is characterized by frequent post-operative pain and can decrease the patient's quality of immediate postoperative life and sometimes…
- Trial name
- VSD (NCT02819544)
- Testing
- Sodium chloride administration, Ropivacaine administration
- Where
- 2 sites in France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Anterior Cruciate Ligament Rupture, Pain, Postoperative
Effect of LIA on Postoperative Pain Following ACL Reconstruction
An anterior cruciate ligament (ACL) rupture is one of the most common sport injuries, which typically develops after a sudden knee torsion.
- Trial name
- NCT03873077
- Testing
- local infiltration analgesia
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- Algemeen Ziekenhuis Maria Middelares
Pain, Postoperative, Pain
Use of Local Infiltration Analgesia Following Total Hip Arthroplasty
The primary aim of this study is to evaluate if multiple postoperative administrations with a solution of ropivacaine, ketorolac and epinephrine into the operating field through a catheter would affect morphine consumption.
- Trial name
- NCT01344395
- Testing
- ropivacaine and ketorolac, Ketorolac
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Aarhus
Serratus Plane Block, Chronic Pain
Serratus Plane Block in Preventing Postoperative Pain of Mastectomy
A prospective, double-blinded randomized controlled, 1-year follow-up study was designed to compare the analgesic effect of serratus plane block (SPB) after breast cancer surgery.
- Conditions
- Serratus Plane Block, Chronic Pain, Breast Cancer
- Trial name
- NCT03615430
- Testing
- serratus plane block with local anesthetic, serratus plane block with saline
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Feng Xia
Rib Fractures
Ultrasound-guided Erector Spinae Plane Blocks
The purpose of this study is to determine the feasibility of using the ultrasound-guided erector spinae plane blocks to provide additional pain relief to patients with rib fractures in the Emergency Department (ED) and Intensive…
- Trial name
- NCT04916691
- Testing
- EPSB for rib fractures, Ropivacaine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain, Postoperative, Anesthesia, Local
Postoperative Pain Relief With Transversus Thoracis Muscle Plane Block After Cardiac Surgery
This study aims to investigate the effect of transversus thoracis muscle plane block (TTP), using repeated boluses of ropivacaine via catheter, on postoperative pain and oxycodone consumption after elective cardiac surgery with…
- Conditions
- Pain, Postoperative, Anesthesia, Local, Coronary Artery Disease, Heart Valve Diseases
- Trial name
- TTPcat (NCT04916418)
- Testing
- Ropivacaine
- Where
- Finland
- Volunteers
- 120 people
- Sponsor
- Turku University Hospital
Knee Osteoarthritis, Total Knee Arthroplasty
Adductor Canal Block Methods in Bilateral Total Knee Arthroplasty
This study aims to compare the analgesic efficacy of surgeon-performed intraoperative adductor canal block (ACB) and ultrasound-guided anesthesiologist-performed ACB in patients undergoing bilateral total knee arthroplasty (TKA).
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Postoperative Pain, Peripheral Nerve Block
- Trial name
- NCT07506629
- Testing
- Surgeon-Performed Adductor Canal Block, Ultrasound-Guided Adductor Canal Block
- Volunteers
- 48 people
- Sponsor
- Yonsei University
Analgesia, Labor Pain
Effect of Epidural Hydromorphone Combined With Ropivacaine in Labor Analgesia
The purpose of this study is to compare the effects of three different doses of hydromorphone combined with ropivacaine and sufentanil combined with ropivacaine in epidural labor analgesia through prospective clinical trials, so…
- Trial name
- NCT05901441
- Testing
- Hydromorphone, Sufentanil, Ropivacaine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Post-operative Pain
Presacral Nerve Block Versus Sham Block on Post-operative Pain for Total Laparoscopic Hysterectomy
The study is a single-center parallel group randomized controlled trial comparing the administration of a presacral nerve block using 20mL of local ropivacaine 5.0mg/ml versus 20mL of normal saline (sham block) on post-operative…
- Trial name
- NCT05953766
- Testing
- Ropivacaine injection, Normal saline injection
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Pain
ESPBs vs TAPs for Satisfactory Analgesia Following DIEP Surgery
Breast cancer is the second most common cancer diagnosed in American women . For patients who have undergone surgical mastectomy, autologous breast reconstruction is an alternative option to breast implants.
- Trial name
- NCT06091241
- Testing
- Pre-operative Erector Spinae Plane block prior to DIEP surgery, Pre-operative Transversus Abdominus Plane blocks prior to DIEP surgery
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Kansas Medical Center
Obstruction of Pelviureteric Junction
The Efficacy and Safety of Local Anesthetic Infusion With Ropivacaine
The investigators propose a prospective blinded randomized control trial (RCT) to assess the efficacy and safety of a simple method of continuous infusion of a local anesthetic, ropivacaine, via a surgical wound to control pain…
- Trial name
- NCT00930046
- Testing
- Ropivacaine wound catheter, Saline wound catheter
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- Boston Children's Hospital
Lung Cancer, Pain, Postoperative
Optimal Postoperative Pain Management After Lung Surgery (OPtriAL)
Adequate pain control after video-assisted thoracoscopic surgery (VATS) for lung resection is important to improve postoperative mobilisation, recovery, and to prevent pulmonary complications.
- Conditions
- Lung Cancer, Pain, Postoperative, VATS, Locoregional Anaesthesia
- Trial name
- NCT05491239
- Testing
- Thoracic epidural analgesia, Continuous regional paravertebral block, Single shot intercostal nerve block
- Where
- Netherlands
- Volunteers
- 450 people
- Sponsor
- Maxima Medical Center
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