Clinical trials: Ropivacaine
Acute Postoperative Pain
Cryoneurolysis for Acute Postoperative Pain Following Total Knee Arthroplasty
Cryoneurolysis is a regional anaesthetic technique that works by freezing peripheral sensory nerves. This technique can potentially provide analgesia after total knee arthroplasty (TKA).
- Trial name
- CRISPP (NCT06088602)
- Testing
- Cryoneurolysis
- Where
- Denmark
- Volunteers
- 44 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Scoliosis Idiopathic Adolescent
The Effect of Dexamethasone Administration Route and Local Anesthetic Concentration on Pain, Inflammatory Response, and Neuromonitoring in Children Undergoing Scoliosis Correction
Scoliosis correction surgery in children is a complex procedure with significant risks, including postoperative pain, inflammatory response, and potential neurological complications.
- Trial name
- NCT06789029
- Testing
- perineural Dexamethasone, intravenous Dexamethasone
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Poznan University of Medical Sciences
Postoperative Analgesia
To Compare the Analgesic Effects of Different Nerve Block Analgesia Methods in Thoracoscopic Surgery
Comparison of analgesic effects of ultrasound-guided thoracic paravertebral block, erector spinae muscle block, thoracic paravertebral block combined with erector spinae muscle block, and intercostal nerve block in thoracoscopic…
- Trial name
- NCT06598852
- Testing
- TPVB group, ESPB group, TPVB combined ESPB group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The First Hospital of Qinhuangdao
Upper Extremity Injury Trauma
Ropivacaine Volume for Ultrasound-guided Retrograde Infraclavicular Brachial Plexus Block
The retrograde infraclavicular brachial plexus block has been proved an effective and safe approach. Realtime ultrasound guide will facilitate a successful peripheral nerve block.
- Trial name
- NCT01334619
- Testing
- appropriate volume of 0.5% ropivacaine
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Beijing Jishuitan Hospital
Hip Arthropathy, Hip Osteoarthritis
Erector Spinae vs. PENG Block for Total Hip Arthroplasty
Effect of PENG block and ESPB on pain management, and NLR and PLR following knee arthroplasty
- Conditions
- Hip Arthropathy, Hip Osteoarthritis, Hip Pain Chronic
- Trial name
- NCT06083428
- Testing
- Ropivacaine 0.2% Injectable Solution Erector Spinae Plane Block, Ropivacaine 0.2% Injectable Solution - PENG block, Control Test
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Cancer Pediatric
Ultrasound-guided Selective Supraclavicular Nerve Block for Postoperative Pain Control in Pediatric Patients.
This prospective randomized controlled trial aims to investigate the effect of ultrasound-guided selective supraclavicular nerve block on pain control after Hickman catheter, chemoport, or Perm cath insertion in children.
- Trial name
- NCT05015907
- Testing
- Ropivacaine, Control (without intervention)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Seoul National University Hospital
Labor Pain, Analgesia, Epidural
Comparing PIEB and CEI for Labor Pain Relief
The purpose of this randomized controlled trial is to compare the efficacy and safety of two epidural analgesia maintenance methods for labor pain relief: Programmed Intermittent Epidural Bolus (PIEB) and Continuous Epidural…
- Conditions
- Labor Pain, Analgesia, Epidural, Analgesia, Obstetrical, Labor, Obstetric
- Trial name
- COPILOT (NCT07395934)
- Testing
- PIEB + PCEA, CEI + PCEA
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Da Nang Family General Hospital
Analgesics, Opioid, Anesthesia, Endotracheal
Opioid-free Anesthesia as an Alternative to General Anesthesia in Abdominal Surgery
Opioid-free anesthesia (OFA) is a multimodal technique that eliminates intraoperative opioids by combining dexmedetomidine, ketamine, lidocaine, NSAIDs, and regional analgesia.
- Conditions
- Analgesics, Opioid, Anesthesia, Endotracheal, Anesthesia, General
- Trial name
- NCT06380244
- Testing
- anesthesia without opioids
- Where
- Poland
- Volunteers
- 600 people
- Sponsor
- Jagiellonian University
Analgesia, Postoperative Pain
Serratus Anterior Plane Block Versus Intercostal Nerve Block for Postoperative Analgesia
A prospective randomized controlled study was undertaken to compare the postoperative analgesic effect between ultrasound-guided serratus anterior plane block and intercostal nerve block after video-assisted thoracoscopic…
- Conditions
- Analgesia, Postoperative Pain, Lung Cancer
- Trial name
- NCT04250272
- Testing
- Thoracoscopic lobectomy
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyungpook National University Hospital
Pectus Excavatum
A Comparison Trial Between PCA and Epidural Analgesia for Pectus Excavatum Repair
The aim of this study is to compare the efficacy of epidural and IV analgesia in controlling pain in patients undergoing Nuss repair of pectus excavatum.
- Trial name
- NCT02056301
- Testing
- Hydromorphone, Morphine
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Postoperative Pain Management in Total Knee Arthroplasty
Dexmedetomidine as an Adjunct to Periarticular Ropivacaine in Total Knee Replacement: A Pilot Randomised Controlled Trial
This study aims to evaluate whether adding dexmedetomidine to ropivacaine-based periarticular infiltration (PAI) improves postoperative pain control in patients undergoing total knee replacement (TKR).
- Trial name
- NCT07176065
- Testing
- Ropivacaine + saline solution, Ropivacaine + Dexmedetomidine
- Where
- Malaysia
- Volunteers
- 60 people
- Sponsor
- University of Malaya
Pain, Postoperative
Preemptive Co-infiltration of Dexamethasone Palmitate With Ropivacaine for Postoperative Pain in Major Spinal Surgery
Patients undergoing major spinal surgery usually experience moderate-to-severe postoperative pain. Inadequate pain control may lead to severe complications.
- Trial name
- NCT05693467
- Testing
- Dexamethasone palmitate emulsion(DXP) plus ropivacaine, Ropivacaine alone
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Beijing Tiantan Hospital
Pain, Postoperative
Thoracic Paravertebral Block for Postoperative Analgesia After Video-assisted Thoracic Surgery.
The use of paravertebral catheters is a recommended technique to achieve postoperative analgesia after thoracic surgery. To date there is no consensus on which drug regime (local anesthetics with or without opioid) is best.
- Trial name
- PARAVI (NCT01082744)
- Testing
- Ropivacaine + Sufentanil, Ropivacaine
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Hospices Civils de Lyon
Post-operative Pain
Comparison of Preoperative Ultrasound Guided Pectoralis Nerve Block Placement Versus Intra-operative Placement: A Prospective Randomized Trial
This study investigates the use of post-operative on-Q pain catheters for tissue expander based breast reconstruction, versus conventional ultrasound-guided blocks placed pre-operatively.
- Trial name
- NCT03201809
- Testing
- On-Q, Ultrasound guided pectoral nerve block
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Pain, Postoperative, Pain, Abdominal
Optimal Peripheral Nerve Block After Minimally Invasive Colon Surgery
The purpose of the trial is to identify the "most simple non-inferior of three different methods", placebo, laparoscopic assisted transverse abdominal plane block (L-TAP) and ultrasound guided TAP block (US-TAP), using…
- Conditions
- Pain, Postoperative, Pain, Abdominal, Analgesia, Surgery
- Trial name
- OPMICS (NCT04311099)
- Testing
- Active drug, Injection of Ropivacaine - Ultrasound-guided transverse abdominal plane block, Injection of Ropivacaine - Laparoscopic assisted transverse abdominal plane block
- Where
- 5 sites in Denmark
- Volunteers
- 360 people
- Sponsor
- Claus Anders Bertelsen, PhD, MD
Adhesive Capsulitis, Frozen Shoulder
The Effect of 3 Ropivacaine Suprascapular Nerve Blocks in Subacute Adhesive Capsulitis: a Randomized Controlled Trial
Patients presenting with subacute, less than 6 months of evolution, adhesive capsulitis are randomly attributed to the control or study group.
- Conditions
- Adhesive Capsulitis, Frozen Shoulder, Nerve Block
- Trial name
- NCT02944526
- Testing
- Ropivacaine Monohydrochloride
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- Clinique Saint-Jean, Bruxelles
Postoperative Pain
A Comparison of Naropin and Ketorolac for Postoperative Analgesia After Total Knee Arthroplasty
The purpose of this study is to determine wether ketorolac is effective in the treatment of postoperative pain after total knee arthroplasty
- Trial name
- NCT00868348
- Testing
- Ketorolac, Saline
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Aarhus
Degenerative Joint Disease
Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty
To compare two methods of post-operative pain management in patients undergoing total hip arthroplasty. There is a perception that the periarticular injections may not be as effective in controlling post-operative pain.
- Trial name
- DA THA pain (NCT02904993)
- Testing
- L2 paravertebral block, periarticular injection group
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Pain, Nerve Block
The Effect of Bilateral Infraorbital and Infratrochlear Nerve Block on Perioperative Period of Hypophysectomy
The endoscopic binostril transnasal transsphenoidal resection of pituitary procedures often cause intense pain which is difficult to suppress at the depth of conventional general anesthesia, resulting in severe hemodynamic…
- Trial name
- NCT05555147
- Testing
- nerve block with 0.5% ropivacaine, without any nerve block
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
Postoperative Pain
Effect of S-ketamine in Cesarean Section Combined Anesthesia
To compare the anti-hyperalgesia effect between S-ketamine with placebo for Maternal receiving elective Cesarean Section under Combined spinal and epidural analgesia.
- Trial name
- NCT05414006
- Testing
- S-ketamine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.