Clinical trials: Ropivacaine
Labor Pain
Comparison of PIEB vs CEI for Labor Analgesia
The aim of this prospective, doubled-blinded randomized study is to compare two modes of epidural analgesia delivery, programmed intermittent epidural boluses (PIEB) versus continuous epidural infusion (CEI) with patient…
- Trial name
- NCT02949271
- Testing
- Programmed Intermittent Epidural Bolus, Continuous Epidural Infusion, Ropivacaine
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Duke University
Postoperative Pain, Midline Laparotomy
Efficacy of Adding Intrathecal Morphine to Erector Spinae Plane Block for Postoperative Analgesia After Midline Laparotomy
This study evaluates whether combining two distinct pain-relief techniques-a peripheral nerve block called the Erector Spinae Plane Block (ESPB) and a low-dose spinal medication injection called Intrathecal Morphine…
- Trial name
- NCT07720739
- Testing
- Intrathecal Morphine, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Sohag University
Respiratory Insufficiency
Incidence Of Hemidiaphragmatic Paralysis After Usg Guided Low Dose Interscalene Brachial Plexus Block
to put a catheter in interscalene brachial plexus USG guided and give a bolus of drug followed by 24 hours continous infusion of drug
- Trial name
- NCT03081728
- Testing
- Interscalene Block with Ropivacaine Hcl 0.2% Inj Vil 10Ml, IV diclofenac and IV paracetamol
- Where
- India
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Orchiopexy, Inguinal Hernioplasty
Ultrasonographic Assessment of Optic Nerve Sheath Diameter in Children Receiving Caudal Block
The recent study revealed that high-volume caudal block caused reduction in cerebral blood flow velocity and cerebral oxygenation. It was supposed to be associated with increased intracranial pressure.
- Conditions
- Orchiopexy, Inguinal Hernioplasty, Hydrocelectomy, Diverticulectomy
- Trial name
- NCT02768493
- Testing
- 1.0 ml/kg of 0.15% ropivacaine, 1.5 ml/kg of 0.15% ropivacaine
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Yonsei University
Osteotomy of Lower Extremity
The Effect of Continuous Epidural Analgesia on Intracranial Pressure by Measuring the Optic Nerve Sheath Diameter Using Ultrasound in Pediatric Patients
Ultrasonography of optic nerve sheath diameter shows a good level of diagnostic accuracy for detecting intracranial hypertension.
- Trial name
- NCT03911804
- Testing
- bolus group and infusion group for epidural block
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Yonsei University
Pain
Contrast and Anesthetic Level With Lumbar Erector Spinae Plan (ESP) Block
As per usual care for spine surgery, participants will have their back cleaned with alcohol and a needle will be placed using ultrasound for the ESP block.
- Trial name
- NCT07174440
- Testing
- Ropivacaine (Epidural analgesia), Dexmedetomidine, Iohexol
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University Hospitals Cleveland Medical Center
Pain Management, Pain, Postoperative
Intrathecal Morphine Injection Versus Continuous Wound Infiltration After Pancreaticoduodenectomy
This is a prospective randomized open-label noninferiority trial that compares intrathecal morphine injection and continuous wound infiltration after open pancreaticoduodenectomy.
- Trial name
- ITM_PPPD (NCT06761989)
- Testing
- Intrathecal morphine injection, Continuous wound infiltration
- Where
- South Korea
- Volunteers
- 104 people
- Sponsor
- Seoul National University Hospital
Postoperative Pain Following Hysterectomy
TAP Block With Lidocaine and Ropivacaine 0.2% (0.4 ml/kg/Side) for Pain and Opioid Reduction After Hysterectomy
The goal of this study is to evaluate whether the Transversus Abdominis Plane (TAP) block can effectively reduce postoperative pain and opioid consumption in patients undergoing elective hysterectomy.
- Trial name
- TAP (NCT07139691)
- Testing
- Pre-incisional Transversus Abdominis Plane (TAP) block performed under ultrasound guidance. The block will be administered bilaterally using a mixture of lidocaine and ropivacaine 0.2%, Participants in this arm will receive standard analgesia for postoperative pain management following elective hysterectomy
- Where
- Romania
- Volunteers
- 82 people
- Sponsor
- Matild Keresztes
Postoperative Nausea and Vomiting
Effect of a Multimodal Antiemetic Protocol on Postoperative Nausea and Vomiting in Patients Undergoing Flap Surgery for Head and Neck Cancer
This prospective randomized controlled trial evaluates whether a multimodal antiemetic protocol can reduce postoperative nausea and vomiting (PONV) in patients undergoing flap surgery for head and neck cancer.
- Trial name
- NCT07786155
- Testing
- Standard antiemetic and anesthetic protocol, Multimodal antiemetic and anesthetic protocol
- Volunteers
- 72 people
- Sponsor
- Seoul National University Hospital
Overweight
The Retroclavicular Approach for Regional Anesthesia of the Upper Limb in Obese Patients
The goal of this study is to determine the success rate of the retroclavicular approach for the anesthesia of the upper limb in the obese patient population (BMI ≥ 30 kg/m2)
- Trial name
- NCT02086643
- Testing
- Retroclavicular block
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Université de Sherbrooke
Pain, Postoperative, Anesthesia, Local
Improving Pain Relief Following Laparoscopic Ventral Hernia Repair
Aim The general aim of this study is to improve post-operative pain and reduce morphine consumption following laparoscopic ventral hernia repair (LVHR).
- Conditions
- Pain, Postoperative, Anesthesia, Local, Hernia, Ventral, Laparoscopy
- Trial name
- NCT02785276
- Testing
- AutoFuser Pain Pump, Ropivacaine, Normal Saline (0.9%)
- Where
- New Zealand
- Sponsor
- University of Auckland, New Zealand
Regional Anesthesia, Postoperative Pain
Pudendal Block Versus Penian Block For Circumcision In Children
The authors study the efficacy of the pudendal versus penile block for the relief of postoperative pain in children receiving ambulatory circumcision.
- Conditions
- Regional Anesthesia, Postoperative Pain, Circumcision
- Trial name
- NCT03046290
- Testing
- circumcision, Lidocaine, Ropivacaine
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Université Libre de Bruxelles
Laparoscopic Hepatectomy, Nerve Block
TAPB Combined With RSB Versus ESPB for Postoperative Analgesia After Laparoscopic Liver Resection
Postoperative pain after laparoscopic hepatectomy is composed of multiple factors, and the peak pain of postoperative pain mainly occurs within the first 24 hours, so it is particularly important to find an appropriate analgesic…
- Trial name
- NCT06133725
- Testing
- erector spinae plane block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Zhangyi
Post-traumatic Stress Disorder
Stellate Ganglion Block for PTSD
Posttraumatic Stress Disorder (PTSD) is a debilitating condition that affects about 15% of Veterans. Current treatments for Veterans with PTSD include medications and psychological therapies that help to process and desensitize…
- Trial name
- SGB-PTSD (NCT05169190)
- Testing
- Stellate Ganglion Block
- Where
- 6 sites in United States
- Volunteers
- 410 people
- Sponsor
- VA Office of Research and Development
Breast Cancer
Efficacy of Preoperative Pectoral Nerve Block for Intraoperative Opioid Sparing Effect and Postoperative Analgesia
The purpose of this study is to determine whether pectoral nerves blocks（PECS） would reduces the opioid consumption during the surgery and postoperative pain after breast cancer surgery.
- Trial name
- NCT03210220
- Testing
- Pecs II block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Gachon University Gil Medical Center
Anesthesia Complications
Effect of Sufentanil and Ropivacaine
The investigators study the efficacy of epidural sufentanil/ropivacaine for analgesia labor in primiparas so as to decrease perinatal complications of analgesia labor.
- Trial name
- NCT02488291
- Testing
- 0.25 sufentanil, 0.5µg/ml sufentanil, 0.1% ropivacaine
- Volunteers
- 120 people
- Sponsor
- Fudan University
Regional Anesthesia, Diaphragm Issues
Ultrasound Assessment of Diaphragmatic Dysfunction in Regional Anesthesia
Awake thoracic surgery is a feasible and safe alternative to general anesthesia for pulmonary biopsy in interstitial lung disease patients, but there is still no evidence as to its superiority in terms of outcome.
- Conditions
- Regional Anesthesia, Diaphragm Issues, Thoracic Surgery, Ultrasounds
- Trial name
- NCT04700943
- Testing
- Regional awake anesthesia
- Where
- Italy
- Volunteers
- 41 people
- Sponsor
- University of Turin, Italy
Distal Radius Fractures, Lidocaine
Ultrasound-guided Infraclavicular Block With Lidocaine or Ropivacaine for Closed Reduction of Distal Radius Fractures
To investigate the feasibility of the lateral infraclavicular plexus brachialis (LIC) block for acute closed reduction of distal radius fractures, the investigators will compare the pain-relieving and muscle-relaxing properties…
- Conditions
- Distal Radius Fractures, Lidocaine, Ropivacaine, Fracture Dislocation
- Trial name
- NCT06379490
- Testing
- Ropivacaine 0.2% Injectable Solution, Lidocaine epinephrine, Ropivacaine 0.5% Injectable Solution
- Where
- Denmark
- Volunteers
- 67 people
- Sponsor
- Nordsjaellands Hospital
Pain After Abdominal Surgery
A Clinical Trial Evaluating the Efficacy and Safety of Local Infiltration of RF16001 for Injection for Analgesia After Total Hip Arthroplasty in China
A multicenter, randomized, double-blind, placebo-positive, parallel-controlled, phase Ⅲ clinical trial was conducted to investigate the efficacy and safety of RF16001 local infiltration for analgesia after total hip arthroplasty.
- Trial name
- NCT07872826
- Testing
- RF16001 for injection, Ropivacaine hydrochloride injection, 0.9% sodium chloride injection
- Where
- China
- Volunteers
- 300 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pain
Local Infiltration Analgesia for Hip Arthroscopy
The purpose of this study is to examine if ultrasound guided infiltration of local anesthetic solution around the hip joint will provide effective pain control after hip arthroscopy.
- Trial name
- NCT01454518
- Testing
- Infiltration of local anesthetic, Normal Saline Injection
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Trinity Health Of New England
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