Clinical trials: Ropivacaine
Post-craniotomy, Pain
Pre-emptive Scalp Infiltration With Low-dose Flurbiprofen and Ropivacaine for Postoperative Analgesia After Craniotomy
Post-craniotomy pain is common and often associated with poor outcomes. Flurbiprofen axetil (FA) is an injectable NSAID for postoperative analgesia, however, the impact of local FA, remains elusive on post-craniotomy pain.
- Trial name
- NCT07209345
- Testing
- FA+Ropivacaine, Ropivacaine
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Beijing Tiantan Hospital
Colon Cancer, Rectal Cancer
Effects of Abdominal Nerve Block on Postoperative Recovery in Patients Undergoing Gastrointestinal Surgery
To explore the effect of general anesthesia combined with transversus abdominis plane block (TAPB) and/or rectus sheath block (RSB) on the recovery of patients with gastrointestinal tumor after surgical treatment.
- Conditions
- Colon Cancer, Rectal Cancer, Gastric Cancer
- Trial name
- NCT04147481
- Testing
- Group Abdominal Nerve Block with local anesthetics, Group Abdominal Nerve Block with saline
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Yi Liu
Pain, Sciatic Block
Trial Comparing Duration of Analgesia After Popliteal Fossa Sciatiac Nerve Block With Ropivacaine 0.5% When Combined With Placebo, Dexamethasone 4mg or Dexamethasone 8 mg
The purpose is to find out if the addition of dexamethasone to ropivacaine 0.5% increases the duration of pain relief provided by popliteal sciatic nerve block performed for foot/ankle surgery.
- Trial name
- NCT01641419
- Testing
- Dexamethasone 4 mg, Dexamethasone 8 mg
- Where
- United States
- Sponsor
- Baylor College of Medicine
Hip Fractures
Anesthesia And Post-operative Mortality After Proximal Femur Fractures
This study evaluates the effect of anesthesia on mortality after surgical repair of proximal femur fracture. Patients will receive either a subarachnoid block or a combination of peripheral nerve blocks and light general…
- Trial name
- NCT02406300
- Testing
- Subarachnoid Anesthesia, PNB/GA, ropivacaine
- Where
- Portugal
- Volunteers
- 57 people
- Sponsor
- Centro Hospitalar do Porto
Post-operative Pain, Inguinal Hernia
Effects of Transverse Abdominis Plane Block Guided by Ultrasound on the Postoperative Analgesia and Quality of Lives Among the Patients Undergo Inguinal Hernia Repair
The incidence of post-operative pain after open inguinal hernia repair is high and impair the quality of lives of the patients.The purpose of this study is to determine whether transverse abdominis plane block combined with…
- Trial name
- NCT02292095
- Testing
- TAPB group, PCIA group
- Where
- China
- Volunteers
- 260 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Hip Fractures
US-guided FICB After Hip Fracture: the Effect of the Local Anesthetic Volume on the Quality of Preoperative Analgesia
participants were randomly divided into three groups : group 30 , group 40 and group 50 . for all the three groups an ultrasound guided supra-inguinal fascia iliaca block had been performed.
- Trial name
- NCT04692857
- Testing
- supra inguinal fascia iliaca block
- Where
- Tunisia
- Volunteers
- 75 people
- Sponsor
- University Tunis El Manar
Elderly, Total Knee Arthroplasty
Dexmedetomidine as an Adjuvant for Femoral Nerve Block and Functional Recovery After Total Knee Arthroplasty
Femoral nerve block (FNB) is a first-line analgesic technique for multimodal analgesia after total knee arthroplasty (TKA). Recent studies and meta-analysis indicate that dexmedetomidine combined with local anesthetics for FNB…
- Conditions
- Elderly, Total Knee Arthroplasty, Femoral Nerve Block, Dexmedetomidine
- Trial name
- NCT04642651
- Testing
- Dexmedetomidine
- Where
- 2 sites in China
- Volunteers
- 170 people
- Sponsor
- Peking University First Hospital
Pelvic Bone Injury, Pelvis Injury
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
The goal of this observational clinical trial is to assess the impact of Regional Anesthesia (RA) techniques with the strongest anatomical and scientific support in controlling acute post-operative pain in pelvic/acetabular…
- Conditions
- Pelvic Bone Injury, Pelvis Injury, Acetabular Fractures, Acetabular Surgery
- Trial name
- RELIEVED (NCT07072286)
- Testing
- Regional Anesthesia, Multimodal analgesia
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Laparoscopic Cholecystectomy
Nerve Blocks vs Local Injections for Post-op Pain Prevention in Laparoscopic Cholecystectomy in Children
The objective of this study is to compare transversus abdominis plane (TAP) blocks to local wound infiltration (LWI) in terms of postoperative pain control in pediatric patients undergoing elective laparoscopic cholecystectomy.
- Trial name
- NCT03022279
- Testing
- TAP Blocks, local wound infiltration
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Brian Wallace Gray
Cancer, Feeding Disorders
Trial Evaluating the Efficacy of the Combination of ROpivacaine With Reference XYlocaine in the Evaluation of Pain During the Installation of Percutaneous Radiological GASTrostomy
Gastrostomy is an intra-gastric nutritional enteral device that could be put in place by percutaneous technique under radiological guidance: allowing local anesthesia.
- Trial name
- GASTROXY (NCT04250805)
- Testing
- Lidocaine, Ropivacaine
- Where
- 2 sites in France
- Volunteers
- 17 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Pain
Use of On-Q Pump for Pain Post C-Section
The main purpose of this study is to examine if pain levels treated with intrathecal (IT) preservative-free morphine (PFM) after a cesarean section improve with the additional use of continuous subfascial wound infiltration with…
- Trial name
- NCT02579629
- Testing
- Ropivacaine 0.1%, Ropivacaine 0.2%, Normal saline
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Emory University
Pain, Postoperative, Kidney Transplant
Transversus Abdominis Plane Catheter Following Kidney Transplantation
Continuous Infusion of Local Anesthetic After Kidney Transplantation This is a phase III, randomized, double-blinded, sham-controlled trial comparing the use of a continuous infusion of local anesthetic via transversus abdominis…
- Trial name
- NCT04786470
- Testing
- Ropivacaine, Saline
- Volunteers
- 120 people
- Sponsor
- Western University, Canada
Upper Limb Nerve Block
The Study of Regional Hemodynamic Changes After Specific Brachial Plexus Block by Ultrasound Guidance
Phase 1 Sympathetic block leads to vasodilatation and increases in blood flow. However, regional hemodynamic changes of radial and ulnar artery after specific nerve block of brachial plexus remains unclear.
- Trial name
- NCT02139982
- Testing
- specific nerve block, ropivacaine
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Wenzhou Medical University
Syncope, Vasovagal
Predictive Factors for Hypotensive Bradycardic Events During Arthroscopic Shoulder Surgery
Patients's demographics and perioperative factors affect the occurrence of hypotensive bradycardic events in the patients undergoing arthroscopic shoulder surgery in the sitting position under interscalene block.
- Trial name
- NCT01926561
- Testing
- Interscalene brachial plexus block
- Where
- South Korea
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Daegu Catholic University Medical Center
Prostate Cancer
Evaluation of Post-operative Biochemical Recurrence in Patients Submitted to Radical Prostatectomy Under General Opioid-free Anesthesia Compared to Conventional General Anesthesia
The use of opioids facilitates angiogenesis and has a proven action in the immune system, mainly in the reduction of natural killer cell activity, favoring the migration of neoplastic cells and inhibiting humoral and cellular…
- Trial name
- NCT03212456
- Testing
- opioid-free group, Opioid Group, transversus abdominal plane block with ropivacaine
- Where
- Brazil
- Volunteers
- 146 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Atrial Fibrillation
Effects of Topical Local Anesthesia of Pulmonary Vein Combined With Vagus Nerve Block on the Incidence of Atrial Fibrillation After Thoracic Surgery
This study intends to explore a new therapy to reduce the incidence of atrial fibrillation in thoracic patient who receive video-assisted thoracoscopic lobectomy .The results of the study are to assess the effects of this new…
- Trial name
- NCT03919786
- Testing
- topical local anesthesia of pulmonary vein combined with vagus nerve block
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Han Yuan
Pain, Osteoarthritis
Adductor Canal Block With Posterior Capsular Injection for Total Knee Replacement
To compare early ambulation and ability to participate in rehabilitation in patients undergoing total knee replacement using two different nerve block techniques for pain control.
- Trial name
- NCT01805661
- Testing
- Canal Block and Capsular Injection, Femoral with Tibial Nerve Block
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Trinity Health Of New England
Breast Cancer, Nerve Block
Erector Spinae Block vs. Placebo Block Study
Regional anaesthesia combined with general anaesthesia has become common in the perioperative management of breast cancer surgery patients. Regional techniques have been recognised to provide excellent post-operative analgesia.
- Conditions
- Breast Cancer, Nerve Block, Regional Anesthesia, Neuromuscular Blockade
- Trial name
- NCT03978780
- Testing
- Erector spinae plane block
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Women's College Hospital
Gastrostomy
EOI Block for Laparoscopic Gastrostomy
This randomized controlled trial will evaluate the efficacy of ultrasound-guided external oblique intercostal fascial plane (EOI) block in reducing intraoperative and postoperative pain in pediatric patients undergoing…
- Trial name
- NCT07119346
- Testing
- EOI block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia
Evaluation of Plasma Concentrations of Intravenous Lidocaine and Epidural Ropivacaine When Used in Combination in Major Abdominal Surgery
Thoracic epidural analgesia (TEA) is the gold standard analgesia of the laparotomy in major abdominal surgery and can be associated with intravenous lidocaine or subtituted by intravenous lidocaine when TEA is contraindicated and…
- Conditions
- Abdominal Surgery by Laparotomy, Thoracic Epidural Analgesia, Analgesia, Lidocaine Adverse Reaction
- Trial name
- LARA (NCT05368753)
- Testing
- Blood sample, Lidocain, ropivacaine
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
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