Clinical trials: Ropivacaine
Postoperative Pain
Catheter-based Peripheral Regional Anesthesia After Orthopedic Surgery to the Foot or Ankle
BACKGROUND Orthopedic surgery can be severely painful, and peripheral regional anesthesia is highly recommended as part of the perioperative pain treatment.
- Trial name
- API-FOOT (NCT03372304)
- Testing
- Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 85 people
- Sponsor
- Nordsjaellands Hospital
Caesarean Section
Effect of Tramadol in Prevention of Postpartum Depression
The incidence of postpartum depression in Europe and the United States is about 10%, while in China the incidence rate of 15.7-39.8%.
- Trial name
- ETPPD (NCT03309163)
- Testing
- Tramadol, Hydromorphone, Ropivacaine (Epidural analgesia)
- Where
- China
- Volunteers
- 1,230 people
- Sponsor
- Xinqiao Hospital of Chongqing
Hallux Valgus
Continuous Tibial Nerve Block Versus Single Shot Tibial Nerve Block
Foot surgery often causes severe and prolonged pain postoperatively. Prior methods of postoperative pain control included oral narcotics, single injection regional techniques and more recently continuous nerve catheters.
- Trial name
- NCT01555216
- Testing
- Single injection posterior tibial nerve block, Posterior tibial nerve catheter
- Where
- United States
- Sponsor
- Northwestern University
Analgesia
Extension of Analgesia by Combined Injection of Dexamethasone and Dexmedetomidine After Arthroscopic Shoulder Surgery
The main objective of the study is to demonstrate the efficacy of Dexmedetomidine on the prolongation of analgesia obtained by interscalenic bloc of the brachial plexus and intravenous injection of Dexamethasone (efficacy…
- Trial name
- INDEX (NCT04394481)
- Testing
- Dexmedetomidine, Ropivacaine, Dexamethasone
- Where
- France
- Volunteers
- 122 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Pain, Total Knee Arthroplasty
Duration of Leg Nerve Blocks With Dexamethasone Added to Local Anesthetic
This is a Randomized Double blinded controlled trial on the effect of adding dexamethasone to Ropivacaine on the duration of pain relief for ultrasound guided femoral, obturator and popliteal block after total knee replacement…
- Trial name
- NCT01511211
- Testing
- Dexamethasone, Ropivacaine
- Where
- United States
- Sponsor
- University of New Mexico
Nerve Block
Efficacy of Compound Betamethasone Injection Combined With Ropivacaine in Ultrasound-guided Intercostal Nerve Block for Chronic Post-thoracotomy Pain
The patients were divided into two groups by random number method: GroupRD1 group and GroupRD2 group were given general anesthesia and intercostal nerve block.The drug for intercostal nerve block was 0.33% ropivacaine +2.333mg…
- Trial name
- NCT05556122
- Testing
- intercostal nerve block, lateral intercostal nerve block, ropivacaine + compound betamethasone
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Affiliated Hospital of Nantong University
Diabetes Type 2
Evaluation of Block Duration in Type 2 Diabetes Patients
Diabete animal studies demonstrated a longer period recovery after local anesthetic injection (perineural administration). No clinical study demonstrated a prolonged nerve block duration in diabete type 2 patients after…
- Trial name
- Diabeteblock (NCT01704612)
- Testing
- ropivacaine
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Pierre and Marie Curie University
Arthritis Knee, Pain, Postoperative
Exparel Use in Adductor Canal Block After Total Knee Arthroplasty
Exparel has been shown to have better pain control compared to previously used infiltration agents, including bupivacaine, while having a minor side effect profile.
- Conditions
- Arthritis Knee, Pain, Postoperative, Opioid Use
- Trial name
- NCT04910165
- Testing
- Exparel, Ropivacaine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital, Pennsylvania
Shoulder Pain, Opioid Use
Multimodal Analgesia in Shoulder Arthroplasty
Opioid medications are associated with many side effects and the risk of abuse or overdose. Orthopaedic surgeons are currently investigating ways to control pain after surgery while limiting the amount of opioid medications…
- Trial name
- NCT03586934
- Testing
- Acetaminophen, Celecoxib 200mg, Celecoxib 400 mg
- Where
- United States
- Sponsor
- Rush University Medical Center
Knee Osteoarthritis
Comparing Femoral Nerve Catheters to Single Shot Femoral Nerve Blocks for Total Knee Replacement Surgery
The purpose of this study is to compare two methods of pain control used during total knee joint replacement surgery. The pain medication that will be used for this study is not experimental.
- Trial name
- NCT02106481
- Testing
- Femoral Nerve Catheters, Single Shot Femoral Nerve Blocks
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Eastern Maine Medical Center
Postoperative Pain, Acute
EOI Block in Otoplasty With Rib Cartilage Graft
This randomized controlled trial aims to evaluate the effect of ultrasound-guided external oblique intercostal (EOI) fascial plane block on postoperative pain control and recovery in pediatric patients undergoing otoplasty with…
- Trial name
- NCT07262944
- Testing
- Ultrasound-guided External Oblique Intercostal (EOI) Fascial Plane Block, Standard postoperative pain management (no EOI block)
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Diaphragmatic Paralysis
Ultrasound-guided Interscalene Block:3mL Ropi Provide Similar Analgesia to 5mL and Less Diaphragmatic Paralysis
Ropivacaine for ultrasound-guided interscalene block: 3mL provide similar analgesia to 5mL with less diaphragmatic paralysis in shoulder arthroscopy surgeries
- Trial name
- NCT04317235
- Testing
- Ropivacaine 0.5% Injectable Solution
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Saint George Hospital
Pain, Postoperative
Comparing the Effect of TAP-catheter and Epidural Catheter on Postoperative Pain After Open Gynecologic Surgery
This study compares the effect on postoperative pain of bolus administration of ropivacaine in Transversus abdominis plane catheter and continuous bupivacain-infusion in epidural catheters following open gynecologic surgery.The…
- Trial name
- NCT01760174
- Testing
- Ropivacaine bolus in transversus abdominis plane catheter, Bupivacain-infusion in epidural catheter
- Where
- Denmark
- Sponsor
- Aalborg University Hospital
Axillary Nerve Block
Chloroprocaine 2% vs Ropivacaine 0.75% in Ultrasound-guided Axillary Nerve Block
The Study evaluate the non-inferiority of Test product (Chloroprocaine 2%) versus Reference product (Ropivacaine 0.75%) in terms of proportion of subjects with a successful block for distal upper limb surgeries Successful block…
- Trial name
- NCT02385097
- Testing
- Chloroprocaine HCl 2%, Ropivacaine 0.75%
- Where
- Switzerland
- Volunteers
- 211 people
- Sponsor
- Sintetica SA
Pain
Optimal Volume, Rate, and Interval of Bolus Nerve Catheters for Shoulder Surgery
The purpose of this study is to determine the ideal delivery of local anesthetics for pain control when using continuous interscalene peripheral nerve catheters for shoulder surgery. The study will be conducted in three stages.
- Trial name
- NCT02946268
- Testing
- Ropivacaine
- Where
- United States
- Sponsor
- Duke University
Knee Osteoarthritis
Adductor Canal Versus Femoral Nerve Block for Analgesia Post Total Knee Arthroscopy
Total knee arthroplasty or replacement (TKA) is a surgery performed for osteoarthritis of the knee which is increasingly performed as the population ages.
- Trial name
- NCT02033603
- Testing
- Ropivacaine
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- Changi General Hospital
Regional Anaesthesia, Cesarean Section
Dose-response Study of Spinally Administered Ropivacaine for Caesarean Section in Tall Parturients
The main goal is to determine the optimum dose of ropivacaine, a local anaesthetic, that provides regional anaesthesia with no or minimum adverse effects (i.e.
- Trial name
- NCT03936790
- Testing
- Ropivacaine, Fentanyl
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Paraskevi Matsota
Wound Heal, Diabetic Foot Ulcer
Effect of New High Ankle Block on Wound Healing After the Operation of Debridement of Diabetes Foot
The goal of this clinical trial is to compare high ankle block and general anesthesia on wound recovery and ankle blood flow perfusion after diabetes foot surgery in diabetics.
- Trial name
- NCT06395961
- Testing
- high ankle block, general anesthesia
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Xuzhou Central Hospital
Gastrostomy
EOI Block for Laparoscopic Gastrostomy
This randomized controlled trial will evaluate the efficacy of ultrasound-guided external oblique intercostal fascial plane (EOI) block in reducing intraoperative and postoperative pain in pediatric patients undergoing…
- Trial name
- NCT07119346
- Testing
- EOI block
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Locoregional Analgesia in Breast Surgery
Double-blind Study to Assess effectIveness of Pectoral Nerves Block After Breast Surgery on Piritramide Consumption
The aims of this study is to compare the effectiveness of pecs block associated to a general anesthesia in terms of Piritramide consumption compared with a general anaesthesia alone and the chronic pain incidence in patients that…
- Trial name
- DESIGN (NCT02655965)
- Testing
- Ropivacaine, Clonidine, Sodium Chloride
- Where
- Belgium
- Volunteers
- 54 people
- Sponsor
- Jules Bordet Institute
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