Clinical trials: Ropivacaine
Pain, Postoperative
Preemptive Co-infiltration of Triamcinolone Acetonide With Ropivacaine for Postoperative Pain in Major Spinal Surgery
Patients undergoing major spinal surgery usually experience moderate to-severe postoperative pain. Inadequate pain control may lead to severe complications.
- Trial name
- NCT06801587
- Testing
- Triamcinolone acetonide plus ropivacaine, Ropivacaine alone
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Fang Luo
Postoperative Pain, Lumbar Disc Surgery
Efficacy and Safety of Ultrasound-guided Lateral Thoracolumbar Interfascial Plane Block (TLIPB) for Postoperative Pain in Patients Undergoing Herniated Lumbar Disc Surgery
Surgery of the lumbar spine is characterized by diffuse and severe postoperative pain. In recent years, some case reports indicate that the thoracolumbar interfascial plane block (TLIPB) can reduce postoperative pain after spinal…
- Trial name
- NCT03951038
- Testing
- PCIA group, Lateral TLIPB group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Internal Carotid Artery Stenosis
Ultrasound-guided Intermediate Cervical Plexus Block
The investigators test with the present study design, whether an ultrasound-guided blockade of the cervical plexus in combination with an additional application of local anesthetic to the superficial cervical ansa (facial nerve…
- Trial name
- NCT02794974
- Testing
- cervical plexus block, facial nerve block, perivascular block
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Helios Research Center
Adverse Effects in the Therapeutic Use of Analgesic, Antipyretic and Anti-Inflammatory Drug, Unspecified
A Prospective Study on the Comparison of Postoperative Pain According to the Use of Cocktail Therapy in Laminoplasty
This study is the first prospective randomized controlled trial to analyze the effects and safety of multimodal cocktail injections after cervical laminoplasty
- Trial name
- NCT06113497
- Testing
- Cocktail injection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kyunghee University Medical Center
Total Knee Arthroplasty
The Influence of the Femoral Nerve Block on Quadriceps Strength
Total knee replacement is a frequent procedure in Québec's hospitals and the muscular strength of the quadriceps is the best indicator of the patient's functional recovery post surgery.
- Trial name
- NCT01111513
- Testing
- 48-hour ropivacaine infusions, Single dose ropivacaine, Patient controlled analgesics
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- Hopital de l'Enfant-Jesus
Breast Cancer
Regional Anesthesia for Breast Surgery
Patients scheduled for mastecotmy will be randomized to receive either an ultrasound-guided double space paravertebral block or a PECSII + parasternal block.
- Trial name
- NCT03941223
- Testing
- PECSII and paravertebral blocks
- Where
- Italy
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Local Anesthetic Toxicity, Regional Anesthesia Morbidity
Ropivacaine Plasma Concentrations After Fascial Blocks in Elective Cardio-thoracic and Abdominal Surgery
Primary aim: observe the incidence of systemic toxicity from local anesthetic (LAST) after performing fascial blocks in patients undergoing elective cardio-thoracic and abdominal surgery.
- Conditions
- Local Anesthetic Toxicity, Regional Anesthesia Morbidity, Postoperative Pain
- Trial name
- NCT05592691
- Testing
- Fascial block
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- University of Turin, Italy
Obesity, Morbidly Obese
Novel SaCoVLM™ Video Laryngeal Mask Airway as an Intubation Conduit in Morbidly Obese Bariatric Surgery
Background: The SaCoVLM™ video laryngeal mask is a novel video-assisted device that integrates the functions of both a dual-channel laryngeal mask airway (LMA) and an intubating laryngeal mask airway (ILMA).
- Trial name
- NCT07573813
- Testing
- SaCoVLM™ in Difficult Airways
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Yongtao Sun
Lower Extremity Fracture
Diffusion Length of Local Anesthetics in the Subparaneural Space and Duration of Analgesia
Ultrasound-guided popliteal sciatic nerve block is a widely practiced technique to provide anesthesia or analgesia for below-knee surgeries.
- Trial name
- NCT05437835
- Testing
- Ropivacaine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- General Hospital of Ningxia Medical University
Hip Osteoarthritis
Effect of Local Infiltration Anesthesia in a Hip Arthroplasty Fast Track Program.
Fast-track programs in Orthopaedic Surgery require early motion that can only be achieved by optimal pain management protocols. Multimodal analgesia protocols including local infiltration anesthesia (LIA) have obtained excellent…
- Trial name
- NCT03513276
- Testing
- 100cc of 2% ropivacaine, Saline Solution, Adrenaline 10mcg/ml
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Hospital Mutua de Terrassa
Lower Limb Injury
Multimodal Analgesia Versus Peripheral Nerve Block for Postoperative Pain Management After Lower Limb Injury Surgery
The purpose of this clinical trial is to understand the effectiveness of femoral nerve block, combined sciatic and femoral nerve block, lumbar plexus block, epidural block, and intravenous analgesia pump in the application of…
- Trial name
- NCT06779968
- Testing
- Femoral Nerve Block, Combined Sciatic and Femoral Nerve Block, Lumbar plexus block
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xiaguang Duan
Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery
The Effects of Serratus Anterior Plane Block on Postoperative Quality of Recovery and Analgesia After Video-assisted Thoracoscopic Surgery
Postoperative pain still remains a challenging problem in patients undergoing video-assisted thoracoscopic surgery (VATS). However, there is no gold standard for regional analgesia for VATS.
- Trial name
- NCT02311517
- Testing
- Ropivacaine, Normal Saline
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Yonsei University
Cytoreductive Surgery, Hyperthermic Intra-peritoneal Chemotherapy
Quadratus Lumborum Block After Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy
This study aims to assess whether transmusculr quadratus lomborum block (QL block) can reduce postoperative pain after cytoreductive surgery and hyperthermic intra-peritoneal chemotherapy (CRS and HIPEC).
- Conditions
- Cytoreductive Surgery, Hyperthermic Intra-peritoneal Chemotherapy, Peritoneal Cancer
- Trial name
- NCT05597683
- Testing
- Arm I (QL block and multimodal analgesia), Arm II (multimodal analgesia without regional block)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Gangnam Severance Hospital
Single Port Laparoscopic Adnexal Surgery
Effect of Preoperative Rectus Sheath Block on Quality of Recovery in Single Port Laparoscopic Adnexal Surgery
In this study, the investigators aimed to demonstrate if the quality of recovery in patients undergoing single-port laparoscopic adnexal surgery, with preoperative rectus sheath block and intraoperative opioid administration…
- Trial name
- NCT05984212
- Testing
- Ultrasound guided rectus sheath block with dexmedetomidine, Ultrasound guided rectus sheath block with normal saline
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Labor Pain
Comparing Effectiveness of CSE Versus DPE for Labor Analgesia
The primary purpose of this study is to determine if there are differences in block quality between the CSE and DPE techniques for labor analgesia in parturients in active labor.
- Trial name
- NCT05068661
- Testing
- Ropivacaine 0.1% Injectable Solution, Bupivacaine 0.25% Injectable Solution
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- Duke University
Shoulder Surgery, Interscalene Nerve Block
Effect of 0.5% vs 0.375% Ropivacaine on Autonomous Nervous System
It is established that the local anesthetic that is administered during an interscalene block affects the autonomic outflow to the heart.
- Conditions
- Shoulder Surgery, Interscalene Nerve Block, Ropivacaine
- Trial name
- NCT02125994
- Testing
- Interscalene nerve block
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Larissa University Hospital
Regional Anesthesia Morbidity, Local Anesthetic Drug Adverse Reaction
Plasma Ropivacaine Concentrations After Sciatic Nerve Block in Patients With Chronic Kidney Disease
This prospective observational study aimed to examine the pharmacokinetics of ropivacaine in patients with chronic kidney disease after sciatic nerve block.
- Trial name
- NCT03666845
- Testing
- Sciatic nerve block
- Where
- South Korea
- Volunteers
- 5 people
- Sponsor
- Seoul National University Hospital
Pain, Postoperative
Erector Spinae Plane Block (ESP) Versus Thoracic Epidural Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS) in Pediatric Population; a Randomized, Controlled Study
Aim of the study is to investigate the efficacy and safety of continuous ESP block in children under the age of 10 yrs undergoing video-assisted thoracoscopic procedures, compared to Thoracic Epidural Anesthesia (TEA).
- Trial name
- ESP (NCT04878341)
- Testing
- Erector Spinae Plane Block
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- Vittore Buzzi Children's Hospital
Postoperative Pain Management
Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine
The investigators are evaluating postoperative outcomes in patients undergoing hip replacement surgery performed with either spinal or general anesthesia, who also receive a suprainguinal fascia iliaca block using either…
- Trial name
- NCT07316166
- Testing
- Dexmedetomidine, Ropivacaine
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Rhode Island Hospital
Percutaneous Nephrolithotomy
The Minimal Effective Volume (MEV90) of Ropivacaine 0.75% for Ultrasound-guided Transmuscular Quadratus Lumborum Block
This double-blind dose-finding trial is based on a biased coin up-and-down sequential design, where the volume of local anesthetic administered to each patient depends on the response from the previous one.
- Trial name
- NCT04196270
- Testing
- Ropivacaine injection
- Volunteers
- 40 people
- Sponsor
- Zealand University Hospital
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