Clinical trials: Ropivacaine
Quadratus Lumborum Block, Thoracic Paravertebral Block
A Trial Comparing Quadratus Lumborum Block (QLB) and Paravertebral Block (PVTB) for Postoperative Analgesia in Hepatectomy
Pain after hepatectomy can interfere with the patients' recovery and may contribute to developing long term pain. Opioids, e.g. morphine, fentanyl, sufentanil, works well for postoperative analgesia, but have several side effects…
- Conditions
- Quadratus Lumborum Block, Thoracic Paravertebral Block, Postoperative Analgesia, Hepatectomy
- Trial name
- NCT03540537
- Testing
- Patient-controlled intravenous analgesia, Quadratus Lumborum Block, Thoracic Paravertebral Block
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Acute Cholecystitis, Gangrenous Cholecystitis
Enhanced Recovery in Laparoscopic Cholecystectomy
The study assesses the impact of the modified enhanced recovery protocol on the results of surgical treatment of patients with acute cholecystitis.
- Trial name
- ERLAC (NCT03754751)
- Testing
- Laparoscopic cholecystectomy with the implementation of modified ERAS program, Laparoscopic cholecystectomy with standard perioperative treatment
- Where
- Russia
- Volunteers
- 189 people
- Sponsor
- Pirogov Russian National Research Medical University
Postoperative Pain, Laparoscopic Cholecystectomy
EOIB for Pain After Laparoscopic Cholecystectomy
This prospective, randomized, controlled, assessor-blinded trial will evaluate whether bilateral ultrasound-guided external oblique intercostal block (EOIB) reduces postoperative opioid consumption and improves recovery after…
- Trial name
- NCT07332546
- Testing
- External oblique intercostal block (EOIB), Standard care without regional block
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shiyou Wei
Hip Osteoarthritis
PENG Block vs Suprainguinal FICB vs Lumbar ESPB for Analgesia After Hip Surgery
This randomized, double-blinded, controlled clinical trial compares three motor-sparing regional anesthesia techniques used for postoperative analgesia in patients undergoing hip arthroplasty: the Pericapsular Nerve Group (PENG)…
- Trial name
- NCT07288983
- Testing
- Pericapsular Nerve Group (PENG) Block, Suprainguinal Fascia Iliaca Compartment Block (S-FICB), Lumbar Erector Spinae Plane Block (L-ESPB)
- Where
- Poland
- Volunteers
- 93 people
- Sponsor
- Poznan University of Medical Sciences
Lumbar Spinal Fusion
Efficacy of TLIP Block for Postoperative Analgesia of Lumbar Spinal Fusion
Spinal surgery is associated with severe pain in the immediate postoperative period. In a recent study evaluating pain intensity on the first day after surgery in a large range of surgical procedures, among the six most painful…
- Trial name
- ETLA (NCT04593953)
- Testing
- TLIP
- Where
- 2 sites in France
- Volunteers
- 94 people
- Sponsor
- CMC Ambroise Paré
Pain, Postoperative
Continuous Saphenous Nerve Block for Total Knee Arthroplasty
Our study will compare the use of continuous saphenous nerve block performed at the adductor canal in addition to Local Infiltration Analgesia (LIA) versus a Sham block in addition to LIA for total knee replacement.
- Trial name
- NCT01332045
- Testing
- continuous saphenous nerve block, Saline boluses in nerve catheter
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Henning Lykke Andersen
Respiratory Depression, Anesthesia Morbidity
Effect of Interscalene Block on Ventilatory Function
Interscalene block with local anesthetic impairs ventilation (unilateral diaphragmatic dysfunction). Single injection of local anesthetic induced transitory dysfunction (< 24h).
- Conditions
- Respiratory Depression, Anesthesia Morbidity, Block
- Trial name
- KTBIS (NCT01740453)
- Testing
- ropivacaine 2 mg/ml
- Where
- France
- Volunteers
- 70 people
- Sponsor
- Pierre and Marie Curie University
Pertrochanteric Fracture, Pain, Postoperative
Pericapsular Nerve Group Block for Positional Pain and Postoperative Analgesia in Hip Fractures
The aims of this study are: Evaluate the effectiveness of the pericapsulare blockade of the femoral nerve, the accessory obturator nerve and the obturator nerve in patients with pertrochanteric fractures of the femur, during the…
- Trial name
- NCT05079087
- Testing
- Pericapsular nerve group blockade, Midazolam Ketamine arm
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Sanitaria dell'Alto Adige
Total Shoulder Arthroplasty
Analgesia After Total Shoulder Arthroplasty
The purpose of this study is to determine which medication(s) should be included in the interscalene nerve block (an injection of local anesthetic [numbing medicine] near nerves in the shoulder) for patients undergoing total…
- Trial name
- NCT01782872
- Testing
- Interscalene Block (ISB) - 0.375% Ropivacaine + additives, Interscalene Block (ISB) - 0.2% Ropivacaine + additives, Interscalene Block (ISB) - 0.1% Ropivacaine + additives
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Hospital for Special Surgery, New York
Inguinal Hernia
Paravertebral Blocks: Pilot Study to Compare Nerve Stimulation vs. Anatomic Landmarks in Inguinal Hernia Repair
Primary aim: 1. To compare the nerve stimulation vs. anatomic techniques of paravertebral block of T11-L1 in providing surgical anesthesia for patients undergoing inguinal hernia repair. Secondary aims: 1.
- Trial name
- PVB (NCT00587704)
- Testing
- PVB using nerve stimulation, PVB using anatomic landmarks
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Anorectal Surgery, Pain Management
A Multidisciplinary Perioperative Pain Management
Objective: This study aimed to evaluate the clinical value of a multidisciplinary collaboration (MDC)-based perioperative pain management model.
- Trial name
- NCT07150819
- Testing
- Standard Nursing Care Protocol, MDC-based Pain Management
- Where
- China
- Sponsor
- China-Japan Friendship Hospital
Esophagus Cancer
Rhomboid Intercostal and Subserratum Plane Block for Minimally Invasive Esophagectomy
The objective is to investigate the safety and effectiveness of rhomboid intercostal and subserratum plane (RISS) block for postoperative analgesia after minimally invasive McKeown esophagectomy (MIE-McKeown).
- Trial name
- NCT06092944
- Testing
- Catheterization, Single nerve block, Continuous nerve block
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Luo Fuchao
Elective Surgery of the Spine by Laparotomy
The Tap Block Technique Via the Anterior Approach in Elective Surgery of the Spine
This is a prospective, single-centre, randomised, double-blind trial, comparing TAP block with continuous infiltration of ropivacaine versus placebo.
- Trial name
- TAPBloc Rachis (NCT02055664)
- Testing
- Ropivacaine 0.2%, Chlorure de sodium 0.9%
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Osteoarthritis, Knee
Liposomal Bupivacaine Versus Standard of Care in Total Knee Surgery
The purpose of this study is to determine whether liposomal bupivacaine is effective in the management of pain following total knee arthroplasty, as compared to standard of care analgesia.
- Trial name
- NCT02219087
- Testing
- Liposomal bupivacaine, Standard of Care
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- OhioHealth
Adhesive Capsulitis, Adhesive Capsulitis of Unspecified Shoulder
Suprascapular Nerve Block to Improve Tolerance and Outcomes of Shoulder Hydrodistension in Adhesive Capsulitis
Adhesive capsulitis ("frozen shoulder") causes significant pain and loss of shoulder mobility. Shoulder hydrodistension is an established treatment that can improve movement and reduce symptoms, but the procedure itself may be…
- Conditions
- Adhesive Capsulitis, Adhesive Capsulitis of Unspecified Shoulder, Adhesive Capsulitis, Shoulder, Frozen Shoulder
- Trial name
- SHINE (NCT07380087)
- Testing
- Shoulder Hydrodistention, suprascapular nerve block
- Where
- Portugal
- Volunteers
- 50 people
- Sponsor
- Universidade do Porto
SPINAL Fracture, Pain, Postoperative
Effectiveness of Erector Spinae Plane Block for Percutaneous Arthrodesis of Spinal Fractures
Spinal fracture surgery is a common surgery. Post-operative pain has been reduced by the advent of so-called minimally invasive techniques.
- Trial name
- SPINERECTOR (NCT06200298)
- Testing
- Erector spinae plane block with naropeine [3,75 mg/mL], ESPB with saline 0,9%
- Where
- France
- Volunteers
- 86 people
- Sponsor
- University Hospital, Lille
Epidermolysis Bullosa
Evaluation of the Efficacy of ROPIVACAINE in Children and Young Adults With Hereditary Epidermolysis Bullosa
The purpose of this study is to determine whether topical application of Ropivacaine is effective for treating refractory pain during dressing changes and so improve quality of life of patients (newborn, child, adolescent or…
- Trial name
- EBROPI (NCT03730584)
- Testing
- Ropivacaine, Blood test
- Where
- France
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Achalasia, Esophageal Achalasia
Ropivacaine For Post-POEM Pain Control
POEM (Peroral Endoscopic Myotomy) is an endoscopic procedure most commonly used to treat achalasia. Achalasia is a disorder resulting from the inability of esophageal muscles to relax.The POEM procedure, performed under general…
- Trial name
- NCT03702647
- Testing
- Ropivacaine, Normal saline
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Lawrence Charles Hookey
Frozen Shoulder, Adhesive Capsulitis
Frozen Shoulder Treatment With Intra-Articular Corticosteroid Injection and Suprascapular Nerve Block
Frozen shoulder remains a challenging disease to treat as pain and loss of range of motion can persist for many months or even years.
- Trial name
- FROSTBLOCK (NCT06229964)
- Testing
- SSNB + IACI
- Where
- Belgium
- Volunteers
- 110 people
- Sponsor
- Universitair Ziekenhuis Brussel
Stillborn Caesarean Section
Epidural Volume Extension and Intrathecal Use of Local Anesthetics in Cesarean Sections
Intrathecal (i.t.) administration of isobaric bupivacaine, ropivacaine and levobupivacaine with addition of fentanyl for c-section either combined or not with administration of 10 ml of N/S 0,9% epidurally, in order to extent…
- Trial name
- NCT01558713
- Testing
- Bupivacaine- Fentanyl - Normal Saline, Ropivacaine-Fentanyl-Normal Saline, Levobupivacaine- Fentanyl- Normal Saline
- Where
- Greece
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Patras
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