Clinical trials: Ropivacaine
Elective Reconstructive Surgery, Pain, Post Operative
The Efficacy and Safety of Lower Limb Nerve Blocks in Postoperative Analgesia for the Free Flap Donor Sites
The use of free fibular flaps and anterolateral thigh (ALT) flaps for repairing the oromandibular defects is well established, whereas few attentions were focused on postoperative analgesia for the donor area.
- Trial name
- NCT03071185
- Testing
- femoral nerve block, common peroneal nerve block
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xia Zhang
Hypotension
Decision Support for Intraoperative Low Blood Pressure
The purpose of this study is to determine whether a decision support system can improve the adherence to thresholds for low blood pressure by anesthesia providers, which in turn prevents their patients from having organ injury.
- Trial name
- NCT02726620
- Testing
- Attending real-time decision support, In-room real-time decision support, Attending feedback emails
- Where
- United States
- Volunteers
- 22,435 people
- Sponsor
- Vanderbilt University Medical Center
Pain, Postoperative
Intra- Versus Extraarticular Injection of Ropivacaine in Total Knee Arthroplasty
The purpose of this study is to evaluate the optimal site for application of local anesthetics in total knee arthroplasty surgery.
- Trial name
- NCT00632580
- Testing
- intraarticular injection with ropivacaine, extraarticular injection with ropivacaine
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Hvidovre University Hospital
Postoperative Pain, Nerve Block
Analgesic Effects of Transversus Thoracic Plane (TTP) Block in Cardiac Surgery
The TTP block is a novel regional anesthetic technique that shows promise in providing analgesia for anterior chest wall incisions and median sternotomy.
- Conditions
- Postoperative Pain, Nerve Block, Cardiac Surgery
- Trial name
- NCT03128346
- Testing
- Transthoracic Transversus Plane Block, Hydromorphone Hydrochloride, Aspirin
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Western University, Canada
Postoperative Pain
Ropivacaine Transversus Abdominis Plane Blocks for Cesarean Section Analgesia
With this research the investigators hope to determine the lowest dose of ropivacaine used in transversus abdominis plane (TAP) blocks that can effectively treat pain in women after cesarean section (c-section).
- Trial name
- TAPROPI (NCT02893423)
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Maimonides Medical Center
Hypospadias
Effect of Caudal and Penile Block on Hypospadias Repair Complications
Hypospadias is one of the most common genitourinary (GU) malformations, seen in approximately 1 of 250 male live births. Common methods of local anesthesia administration for hypospadias surgery include caudal and dorsal penile…
- Trial name
- NCT02851290
- Testing
- Caudal block anesthesia, Dorsal penile nerve block anesthesia
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- Baylor College of Medicine
Knee Osteoarthritis
Population Pharmacokinetics of Ropivacaine
The aim of this study was to investigate the pharmacokinetics of free and total ropivacaine after unilateral and bilateral TKA. A population model was successfully built and peak free ropivacaine concentration stayed below…
- Trial name
- NCT04702282
- Testing
- ropivacain concentration measurements
- Volunteers
- 28 people
- Sponsor
- Hvidovre University Hospital
Analgesia, Labor Pain
Efficacy and Safety of Hydromorphone-ropivacaine Versus Sufentanil-ropivacaine for Epidural Labor Analgesia
The purpose of this study is to compare the effects of three different doses of hydromorphone combined with ropivacaine and sufentanil combined with ropivacaine in epidural labor analgesia through prospective clinical trials, so…
- Trial name
- NCT06036797
- Testing
- Hydromorphone, Sufentanil, Ropivacaine
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Maternal and Child Health Hospital of Hubei Province
Osteoarthritis, Hip
Blood Levels of Local Anaesthetic in Hip Arthroplasty
The primary goal is to evaluate ropivacaine blood concentrations during and after local anaesthetic (ropivacaine) infiltration - the Caledonian technique - for total hip replacement surgery.
- Trial name
- BLAST (NCT01869946)
- Testing
- Ropivacaine
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Golden Jubilee National Hospital
Hallux Valgus and Bunion
Post-Operative Pain and Opioid Reduction Trial After Bunionectomy
This is a Phase 2b, randomized, double blind, placebo and active controlled study with an Ascending Dose Stage and an optional Dose Expansion Stage in subjects undergoing bunionectomy.
- Trial name
- MERIT-2 (NCT05411861)
- Testing
- Analgesic Non Narcotic
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- Cali Pharmaceuticals LLC
Zoster Without Complications
Regional Anesthesia to Relief Zoster Pain
Pain in Herpes is a serious issue for patients. at the acute phase it is a moderate to severe pain . 30% patients will develop a post herpetic neuralgia this percentage up to 70 % after 60 years old.
- Trial name
- NCT04133142
- Testing
- peripheral nerve block, inter fascial nerve block
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System
Pain Management Strategies in Liver Resection Surgery
TEA vs. PVB vs. PCA in Liver Resection Surgery
This study aims to compare the efficacy and safety of three alternative methods of analgesia in patients undergoing complex liver resection surgery: 1) thoracic epidural analgesia (TEA), 2) continuous paravertebral block (PVB)…
- Trial name
- NCT02192879
- Testing
- thoracic epidural, continuous paravertebral catheter, Patient-Controlled Analgesia
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Duke University
Pharmacological Action
Efficacy and Safety of Liposomal Bupivacaine Under ERAS Concept for Postoperative Analgesia of Ultrasound-Guided QLB in Gynecologic Laparoscopic Patients: A Randomized, Single-blind, Active-Controlled Clinical Study
With the development of the concept of comfortable medicine and enhanced recovery surgery (ERAS), optimizing the perioperative management of patients, reducing surgical stress, and reducing postoperative pain can effectively…
- Trial name
- NCT06288841
- Testing
- Ropivacaine injection, Bupivacaine liposome
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Tianjin Medical University General Hospital
Thoracoscopic Surgery, Nerve Block
Comparison of Analgesic Effect and Postoperative Recovery of SAPB Combined With ESPB and TPB After Thoracoscopic Surgery
After thoracoscopic surgery, patients still face moderate to severe pain. How to effectively control pain and promote postoperative recovery of patients is a challenging problem.
- Trial name
- NCT05538429
- Testing
- erector spinal plane combined with serratus anterior plane block
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Zhangyi
Mammary Cancer, Erector Spinae Plane Block
Effect of ESPB on Postoperative Pain in Patients With Breast Cancer Implant Reconstruction
Nowadays, the incidence of breast cancer is the first number of malignant tumors, and the primary treatment method is surgery.With the development of medical technology and concept, radical mastectomy combined breast…
- Conditions
- Mammary Cancer, Erector Spinae Plane Block, Postoperative Pain
- Trial name
- NCT06143020
- Testing
- Erector spinae plane block
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Total Hip Arthroplasty (THA), Postoperative Pain Management
Iliopsoas (IPB) and Pericapsular Nerve Group (PENG) Blocks Comparison on Analgesia and Recovery After Total Hip Arthroplasty
Background: In recent years, regional anesthesia has become more popular because it can reduce pain and the need for strong pain medications like morphine. For hip surgery, the PENG block is already known to be effective.
- Conditions
- Total Hip Arthroplasty (THA), Postoperative Pain Management, Peripheral Nerve Blocks, PENG Block
- Trial name
- NCT06964282
- Testing
- PENG Block, Iliopsoas nerve block
- Where
- Belgium
- Volunteers
- 118 people
- Sponsor
- University of Liege
Pain
Continuous Wound Infiltration for Diminution of Post-surgery Pain After Caesarean Section
A medical approach that warrants continuous and reliable local administration of non-opioid analgesic drugs might substantially improve post-surgery pain management in CS, while decreasing the necessity of staff-dependent…
- Trial name
- dip-Caesar (NCT02828059)
- Testing
- Ropivacaine
- Sponsor
- Jena University Hospital
Local Anesthetic Systemic Toxicity, Anesthesia, Local
Ropivacaine Plasma Concentration With or Without Epinephrine for Posterior Quadratus Lumborum Block
Introduction The posterior Quadratus Lumborum Block (pQLB) has been used in postoperative pain management after Cesarean Section (CS).
- Trial name
- NCT04562103
- Testing
- Epinephrine / Ropivacaine, Ropivacaine
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Muscle Strength, Healthy Volunteers
Adductor Canal Block and Effect of 10 Versus 30 ml Ropivacaine on Muscle Strength: a Randomized Study in Healthy Volunteers
To investigate whether reducing the volume (30 versus 10 ml) ropivacaine injected can reduce the number of subjects with impaired muscle strength following adductor canal block.
- Trial name
- NCT01981746
- Testing
- Adductor canal block with ropivacaine 0.1%
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pediatric ALL
Exploring the Minimum Effective Concentration and Volume of Ropivacaine for Sacral Plexus Anesthesia
The goal of this clinical trial is to explore the minimum effective concentration and volume of ropivacaine for sacral plexus anesthesia.
- Trial name
- NCT06711679
- Testing
- Low-dose ropivacaine, Medium-dose of ropivacaine, High-dose ropivacaine
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Yilin Zhao
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.