Clinical trials: Ropivacaine
Adverse Effects in the Therapeutic Use of Analgesic, Antipyretic and Anti-Inflammatory Drug, Unspecified
A Prospective Study on the Comparison of Postoperative Pain According to the Use of Cocktail Therapy in Laminoplasty
This study is the first prospective randomized controlled trial to analyze the effects and safety of multimodal cocktail injections after cervical laminoplasty
- Trial name
- NCT06113497
- Testing
- Cocktail injection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kyunghee University Medical Center
Labor Pain, Epidural
A Comparison Between 2 Methods of Local Anesthetic Administration for Maintaining Labor Analgesia After Dural Puncture Epidural
Intermittent epidural bolus technique opens a new era of interest for maintaining labor anlagesia. The study examines programmed intermittent epidural bolus technique on a scheduled basis to provider-administered bolus anlgesia…
- Conditions
- Labor Pain, Epidural, Pain, Labor
- Trial name
- NCT05034211
- Testing
- Programmed intermittent bolus epidural, Provider administered analgesia on patient request
- Where
- Greece
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aretaieio Hospital
Postoperative Pain
Study Evaluating the Safety, Efficacy and Pharmacokinetics of SYH9089 Injection in Patients Undergoing Abdominal Surgery.
This is a randomized, double-blind, active drug- and placebo-controlled, dose-escalation clinical study conducted in patients scheduled to undergo abdominal surgery.
- Trial name
- NCT07519109
- Testing
- SYH9089 injection, Ropivacaine hydrochloride, 0.9 % sodium chloride
- Where
- China
- Volunteers
- 60 people
- Sponsor
- CSPC Ouyi Pharmaceutical Co., Ltd.
Labor Pain
Parturient Satisfaction With Epidural Analgesia by PCEA or Manual Boluses
Those prospective parturients that express that they may want an epidural labour analgesia for their delivery will be informed about the possibility to choose between a pump driven epidural or midwife administered intermittent…
- Trial name
- NCT06094946
- Testing
- Ropivacaine Hydrocloride, Fentanyl Citrate
- Where
- Finland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Women's Hospital HUS
Postural Tachycardia Syndrome
Ultrasound Guided Stellate Ganglion Block in Postural Tachycardia Syndrome
This single-center study aims to evaluate both immediate and long-term outcomes of stellate ganglion block (SGB) in a cohort of rigorously phenotyped patients with Postural Tachycardia Syndrome (POTS).
- Trial name
- NCT06953661
- Testing
- Stellate ganglion block, Ropivacaine, Normal saline
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Osteoarthritis, Knee Arthroplasty
Evaluation of Motor Sparing Knee Block to Infiltration Analgesia for Pain Following Knee Arthroplasty
Patients undergoing primary total knee replacement will receive either motor sparing knee block to be performed by anesthesia or periarticular local anesthetic infiltration at the end of surgery by surgeons to assess pain relief…
- Conditions
- Osteoarthritis, Knee Arthroplasty, Pain Management
- Trial name
- NCT02540070
- Testing
- Periarticular, Motor free, Motor free with dex
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Epidural Block, Oesophageal Cancer
The Hemodynamic Effect Between Two Types of Anesthesia in Esophageal Surgery
Continuous Paravertebral block (PVB) was reported to provide less episodes of hypotension than continuous thoracic epidural block (TEB).
- Conditions
- Epidural Block, Oesophageal Cancer, Oesophagectomy
- Trial name
- HEMOBLOC (NCT03185403)
- Testing
- paravertebral block, thoracic epidural block, ropivacaine
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Post Operative Analgesia
Erector Spinae Catheter for Open Heart Surgery
Fast track to Extubation after cardiothoracic surgery is becoming more common after a number of reports showing it is safe and effective. However, It has introduced new challenges to pain control.
- Trial name
- ESPADULT2 (NCT03901612)
- Testing
- Ropivacaine 0.2%, saline 09%
- Where
- Vietnam
- Sponsor
- Vinmec Healthcare System
Postoperative Analgesia
Effectiveness of Interscalene Brachial Plexus Block and Intra-articular Injection of Ropivacaine for Post-operative Analgesia in Arthroscopic Shoulder Stabilization Surgery
This study evaluates two anaesthetic techniques namely interscalene brachial plexus block and intra-articular local anaesthetic injection.
- Trial name
- NCT01589354
- Testing
- Interscalene brachial plexus block, Intra-articular Ropivacaine injection, Ultrasound guided technique
- Volunteers
- 60 people
- Sponsor
- NHS Grampian
Postoperative Pain
Comparison of Bilateral Thoracic Paravertebral Block to Thoracic Epidural Analgesia for Post Operative Analgesia in Patients Undergoing Abdominal Surgery
Pain following abdominal surgery is managed with the use of thoracic epidural analgesia (TEA) where the epidural is inserted in the spine at the level of scapula The risks due to TEA include difficulty with insertion, failure in…
- Trial name
- NCT01735851
- Testing
- Thoracic epidural analgesia, Bilateral Paravertebral block
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Horner's Syndrome
Horner's SD After Thoracic Epidural Block
This study prospectively evaluates the incidence of Horner's syndrome after thoracic epidural anesthesia following continuous thoracic epidural analgesia for mastectomy.
- Trial name
- NCT02130739
- Testing
- thoracic epidural anesthesia, mastectomy, Ropivacaine
- Where
- South Korea
- Volunteers
- 450 people
- Sponsor
- Soonchunhyang University Hospital
Total Knee Arthroplasty
Perineural Dexamethasone for Continuous Femoral Nerve Block
An alternative to improve the quality of postoperative analgesia is to use various perineural adjuvants applicable to peripheral nerve block along with local anesthetics to increase the analgesic effect.
- Trial name
- NCT05487001
- Testing
- dexamethasone group
- Where
- South Korea
- Volunteers
- 18 people
- Sponsor
- Gangnam Severance Hospital
Neuromuscular Blockade
Transmucular Quadratus Lumborum Block: Potential Quadriceps Muscle Weakness
The aim of this study is to examine whether the administration of the TQL block cause motor block of the lumbar plexus and thereby quadriceps muscle weakness.
- Trial name
- NCT05023343
- Testing
- Ropivacaine, Quadriceps muscle strength, Timed Up and Go
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Pain, Postoperative
Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-craniotomy Pain
According to recent studies, patients following craniotomy suffer more than minimal pain; two-thirds of patients experienced moderate to severe pain. Postoperative pain most often occurs within 48 hours after surgery.
- Trial name
- NCT04488315
- Testing
- Dexamethasone lipid microsphere plus ropivacaine, Ropivacaine alone
- Where
- China
- Volunteers
- 130 people
- Sponsor
- Beijing Tiantan Hospital
Total Knee Arthroplasty
Bupivacaine Liposome Suspension Versus a Concentrated Multi Drug Periarticular Injection
Despite a robust multimodal pain management regimen, patients undergoing total knee arthroplasty (TKA) continue to report low satisfaction with postoperative pain management.
- Trial name
- NCT02299349
- Testing
- bupivacaine liposome suspension, concentrated multi drug Ketorlac, Morphine PF, Epinephrine, Ropivicaine, 0.9% NaCL
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TriHealth Inc.
Breast Surgery, Thoracic Paravertebral Block
Erector Spinae Plane Block Versus Thoracic Paravertebral Block for Pain Control in Modified Radical Mastectomy
The aim of the study is to compare the effectiveness of the Erector spinae plane (ESP) block versus thoracic paravertebral (TPV) block in the post-operative pain control after radical mastectomy.
- Conditions
- Breast Surgery, Thoracic Paravertebral Block, Post-operative Pain Control, Erector Spinae Plane Block
- Trial name
- NCT04457115
- Testing
- Thoracic paravertebral block, Erector spinae plane Block
- Where
- Italy
- Volunteers
- 78 people
- Sponsor
- AUSL Romagna Rimini
Laminectomy, Postperative Pain Management
Dexamethasone as ESPB Adjuvant in Lumbar Laminectomy
Laminectomy is a routine procedure for patients with lumbar spinal stenosis, offering significant benefits such as reduced low back pain, alleviation of radiculopathy, and improved motor strength 1 23.
- Conditions
- Laminectomy, Postperative Pain Management, Prostaglandin E2, Lumbal Disc Herniation
- Trial name
- NCT07429708
- Testing
- Bilateral ESPB: Ropivacaine 0.375% + Dexamethasone 5mg, Bilateral ESPB: Ropivacaine 0.375%
- Where
- Indonesia
- Volunteers
- 36 people
- Sponsor
- Udayana University
Pain, Shoulder
Continuous Interscalene Block for Same Day Discharge Following Total Shoulder Arthroplasty
Total shoulder surgeries are associated with considerable postoperative pain which may prevent rehabilitation and early discharge from the hospital.
- Trial name
- NCT01785940
- Testing
- Interscalene block
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Pain
Optimal Volume, Rate, and Interval of Bolus Nerve Catheters for Shoulder Surgery
The purpose of this study is to determine the ideal delivery of local anesthetics for pain control when using continuous interscalene peripheral nerve catheters for shoulder surgery. The study will be conducted in three stages.
- Trial name
- NCT02946268
- Testing
- Ropivacaine
- Where
- United States
- Sponsor
- Duke University
Pancreatic Ductal Adenocarcinoma, Liver, Cancer of, Primary Resectable
Celiac plExus Block to Reduce OpioID Consumption Following Hepato-pancreato-biliary Mini-invasive Surgery
The goal of this study is to assess the efficacy of intraoperative celiac plexus block (CPB) to reduce opioid consumption following laparoscopic hepato-pancreato-biliary surgery
- Trial name
- CEBOIDS (NCT06214533)
- Testing
- Ropivacaine 0.5%, Normal Saline
- Volunteers
- 60 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
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