Clinical trials: Rosuvastatin
Coronary Artery Disease
Pharmacodynamic Effects of Atorvastatin vs. Rosuvastatin on Platelet Reactivity
Patients with coronary artery disease (CAD) are often treated with dual antiplatelet therapy (DAT), including aspirin and clopidogrel, to prevent from recurrent atherothrombotic events.
- Trial name
- PEARL (NCT01567774)
- Testing
- Atorvastatin, Rosuvastatin
- Where
- 2 sites in Italy
- Volunteers
- 100 people
- Sponsor
- University of Roma La Sapienza
Deep Vein Thrombosis, Venous
Rosuvastatin for Preventing Deep Vein Thrombosis
Deep vein thrombosis (DVT)is devastating disease which influencing the mortality and morbidity of patients at-risk like those undergoing orthopedic surgery.
- Conditions
- Deep Vein Thrombosis, Venous, Thrombosis, Prevention
- Trial name
- STOP-DVT (NCT01021488)
- Testing
- Rosuvastatin 20mg/d for 14days, enoxaparin only
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Hallym University Medical Center
Hypercholesterolemia, Dyslipidemia
A Multicenter Study Comparing the Safety and Efficacy of ABT-335 and Rosuvastatin Calcium Combination Therapy to Monotherapy in Subjects With Dyslipidemia
The purpose of this study is to evaluate the safety and efficacy of ABT-335 and rosuvastatin calcium combination therapy to monotherapy in subjects with dyslipidemia.
- Trial name
- NCT00463606
- Testing
- ABT-335 and rosuvastatin calcium, ABT-335, rosuvastatin calcium
- Where
- 168 sites in United States
- Volunteers
- 760 people
- Sponsor
- AstraZeneca
Diabetes Mellitus, Type 2, Overweight
Influence of JY09 on Pharmacokinetics of Metformin , Rosuvastatin , and Digoxin and the QT Interval Study in Overweight Chinese Subjects
This trial is conducted in china. The aim of the trial is as follows: To assess the effect of multiple subcutaneous injections of JY09 injection on the pharmacokinetic (PK) profile of multiple oral doses of metformin…
- Trial name
- NCT06247748
- Testing
- Exendin-4 Fc fusion protein (JY09) injection, Metformin Hydrochloride tablet, Rosuvastatin calcium tablets
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Beijing Dongfang Biotech Co., Ltd.
Dyslipidemia
TA-8995: Its Use in Patients With Mild Dyslipidaemia (TULIP)
The primary objective of this study is to evaluate the efficacy of different doses of TA-8995, a cholesteryl ester transfer protein (CETP) inhibitor, on the elevation of high-density lipoprotein cholesterol (HDL-C) and reduction…
- Trial name
- TULIP (NCT01970215)
- Testing
- TA-8995, Atorvastatin, Rosuvastatin
- Where
- 17 sites in Denmark, Netherlands
- Volunteers
- 364 people
- Sponsor
- Xention Ltd
Elderly
A Clinical Study to Evaluate PK, PD, and PG of Rosuvastatin in the Elderly
A clinical study to evaluate pharmacokinetic, pharmacodynamic, and pharmacogenomic characteristics of Rosuvastatin in the elderly after multiple administration of Rosuvastatin
- Trial name
- NCT03715101
- Testing
- Rosuvastatin
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Hypercholesterolemia
Efficacy of Lapaquistat Acetate Alone or Combined With Rosuvastatin in Subjects With Hypercholesterolemia
The purpose of this study is to evaluate lapaquistat acetate, once daily (QD), taken alone or with rosuvastatin on cholesterol levels in treating patients with elevated cholesterol.
- Trial name
- NCT00249912
- Testing
- Lapaquistat acetate and rosuvastatin, Rosuvastatin
- Where
- 92 sites in United States, Canada
- Volunteers
- 415 people
- Sponsor
- Takeda
Preeclampsia
Effect of Rosuvastatin on the Clinical Features of Preeclampsia
The primary outcome will be the effect of rosuvastatin on the resolution of biochemical features associated with severe PE (↑CRP and IL6). .
- Trial name
- NCT04303806
- Testing
- rosuvastatin
- Volunteers
- 80 people
- Sponsor
- Assiut University
Hypercholesterolemia
The Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients With Primary Hypercholesterolemia
A Multi-center, Randomized, Double-blind, Phase III Clinical Trial to Evaluate the Efficacy and Safety of Combination Therapy of Rosuvastatin and Ezetimibe and Rosuvastatin Monotherapy in Patients with Primary Hypercholesterolemia
- Trial name
- NCT03288038
- Testing
- Rosuvastatin, Ezetimibe
- Where
- 20 sites in South Korea
- Volunteers
- 382 people
- Sponsor
- Shin Poong Pharmaceutical Co. Ltd.
Cardiovascular Risk Factor, Cardiovascular Diseases
The DEtermining Statin Intolerance FOr Rosuvastatin (DESIFOR) Trial
This study will enroll patients who previously were not able to tolerate being on a statin medication due to muscle-related side effects.
- Conditions
- Cardiovascular Risk Factor, Cardiovascular Diseases, Adverse Effect
- Trial name
- DESIFOR (NCT03889314)
- Testing
- Rosuvastatin 20mg
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Minneapolis Heart Institute Foundation
Healthy Volunteers
A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)
This Phase 1 study consists of two parts, all conducted in healthy volunteers (HVs). In Parts 1 and 2, the drug-drug interaction (DDI) potential of ALG-055009 will be explored, where subjects will be assigned to receive multiple…
- Trial name
- NCT06191991
- Testing
- Atorvastatin, ALG-055009, Rosuvastatin
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Aligos Therapeutics
Healthy
Observational Usage Study of Statins in Primary Care in France
To describe the way statins are used in France in primary care, that is to determine patients profile (particularly CV risk factors), to determine the way statins are initiated by general practitioners, to evaluate aftercare and…
- Trial name
- NCT00680082
- Where
- 25 sites in China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Hepatitis C
Dose Finding Trial of Rosuvastatin and Atorvastatin Versus Hepatitis C
Different Doses of rosuvastatin and atorvastatin will be used to see if HCV viral load changes and liver tests change.
- Trial name
- NCT00446940
- Testing
- rosuvastatin, atorvastatin
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Bader, Ted, M.D.
Healthy
Pharmacokinetic Drug Interaction Between Candesartan and Rosuvastatin
The objective of this study is to compare pharmacokinetics after single oral administration of candesartan and rosuvastatin each separately versus coadministration of candesartan and rosuvastatin in healthy male volunteers.
- Trial name
- NCT02079506
- Testing
- Candesartan, Rosuvastatin
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alvogen Korea
Ischemic Stroke, Large-Artery Atherosclerosis (Embolus/Thrombosis)
Study of Predictive Factors Related to Prognosis of Patients With Ischemic Stroke Due to Large-artery Atherosclerosis
This is a single-center prospective cohort study of predictive factors related to prognosis of ischemic stroke due to large-artery atherosclerosis.
- Trial name
- NCT04847752
- Testing
- carotid artery stenting, carotid endarterectomy, Aspirin
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Tongji Hospital
Coronary Artery Disease
Rosuvastatin Pre-Treatment Influences the Risk of Coronary Intervention Study
The aim of this study is to determine whether a pre-treatment with high-dose statin (one day prior and just before intervention, rosuvastatin 20mg/day) has a positive impact on the occurrence of periprocedural myocardial…
- Trial name
- TIPS-3 (NCT01378715)
- Testing
- Rosuvastatin
- Where
- 4 sites in Czechia, Slovakia
- Volunteers
- 400 people
- Sponsor
- University Hospital, Motol
Chronic Hepatitis C
Fluvastatin, Rosuvastatin Added to Pegylated Interferon and Ribavirin
Hypothesis: addition of fluvastatin will increase the cure rate of standard anti-HCV therapy. Summary: This trial is limited to veterans in Oklahoma who qualify for care with the Veterans Administration.
- Trial name
- NCT00487318
- Testing
- standard of care, fluvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Bader, Ted, M.D.
Safety and Impact of Medically Supervised Performance Enhancing Substance Usage in Healthy Elite Athletes
Impact of Medically Supervised Performance-Enhancing Substances (PES) on Elite Athletes
Objectives: The primary objective is to assess the safety and tolerability of medical drugs with the potential to enhance performance (PES) in professional athletes over a 5.5 year period, encompassing a 25-week PES Exposure…
- Trial name
- ASCEND001 (NCT07568574)
- Testing
- Testosterone Enanthate, Testosterone Cypionate, Testosterone Propionate
- Where
- United Arab Emirates
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Enhanced Emirates Limited
Hyperlipidemia
Comparison of the Efficacy and Safety of Cresnon® and Crestor® in Patients With Hyperlipidemia
Comparison of the efficacy and safety of Cresnon® and Crestor® in patients with hyperlipidemia 8-week, active-controlled, open-label, randomized, parallelgroup, fixed-dose, noninferiority, multicenter, phase 4 design
- Trial name
- NCT02280590
- Testing
- Rosuvastatin(Cresnon®), Rosuvastatin(Crestor®)
- Where
- South Korea
- Volunteers
- 223 people
- Sponsor
- Dong-A ST Co., Ltd.
Breast Cancer
Rosuvastatin to Lower Circulating Tissue Factor Bearing Microparticles in Metastatic Breast Cancer
Research studies have shown a strong association between cancer and blood clots in the veins (also known as deep vein thrombosis).
- Trial name
- NCT01299038
- Testing
- rosuvastatin
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Beth Israel Deaconess Medical Center