Clinical trials: Routine care
Trauma
Enhanced Consent for Symptom Provocation Research
The overall goal of the proposed study is to insure the protection and safety of human subjects who have been previously exposed to interpersonal traumatic events and who are participants in symptom provocation research.
- Trial name
- NCT01809899
- Testing
- Enhanced consent procedure, Consent as Usual
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Infiltration of Peripheral IV Therapy
Optical Detection of Intravenous Infiltration:A Pilot Study
This study will examine the use of the ivWatch Model 400 to monitor PIV sites in pediatric patients. Half the participants will be monitored by the device without infiltration notifications and the other half will be monitored by…
- Trial name
- NCT02553421
- Testing
- ivWatch Model 400
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- ivWatch, LLC
Labour Pain
Non-pharmacological Resources in Assisting Labor
The proposed project will be conducted to evaluate the influence of application resources associated with non-pharmacological during labor for pain relief and accelerated phase of expansion.
- Trial name
- NCT01389128
- Testing
- Non-pharmacological resources, Routine care
- Where
- Brazil
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
End Stage Liver Disease
Monitoring of Symptoms and Cognitive Function Using Telehealth
End-Stage Liver Disease (ESLD) is one of the ten leading causes of death in US. It is marked by episodic acute exacerbations of the underlying liver disease which often leads to severe symptoms, poor quality of life, mental…
- Trial name
- NCT03184701
- Testing
- Telehealth
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Albert Einstein Healthcare Network
Diabetes Mellitus, Type 2
Long Term Comparative Effectiveness of Once Weekly Semaglutide Versus Standard of Care in a Real World Adult US Population With Type 2 Diabetes - a Randomized Pragmatic Trial
The main purpose of this study is to compare the effects of semaglutide (Ozempic®) with the effects of other treatments for type 2 diabetes in a normal practice setting.
- Trial name
- NCT03596450
- Testing
- Semaglutide, Standard of care
- Where
- 181 sites in United States, Canada
- Volunteers
- 1,278 people
- Sponsor
- Novo Nordisk A/S
Fibromyalgia
Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial
The purpose of this study is to determine if addition of Transcutaneous Electrical Nerve Stimulation (TENS) to routine physical therapy improves movement-evoked pain in patients with fibromyalgia (FM).
- Trial name
- NCT04683042
- Testing
- Transcutaneous Electrical Nerve Stimulation (TENS) with PT, PT only
- Where
- 6 sites in United States
- Volunteers
- 459 people
- Sponsor
- Kathleen Sluka
Dementia, Depression
Testing the Feasibility of the Individualized Positive Psychosocial Intervention (IPPI)
The goal of this clinical trial is to test the feasibility of the Individualized Positive Psychosocial Interaction (IPPI) with 108 nursing home residents living with dementia and distress or depressive symptoms.
- Conditions
- Dementia, Depression, Behavior
- Trial name
- IPPI (NCT05980299)
- Testing
- Individualized Positive Psychosocial Interaction
- Where
- 7 sites in United States
- Volunteers
- 200 people
- Sponsor
- Miami University
Alzheimer's Disease, Dementia
LifeZig Personalized Reminiscence Video With Slideshows and Music for Individuals With Alzheimer's and Dementia
The LifeZig Project is a research study of a new reminiscence activity for individuals with Alzheimer's Disease (AD) and other types of dementia, based on the LifeZig system, with personalized video channels containing old…
- Trial name
- Lifezig (NCT00759863)
- Testing
- Lifezig
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Photozig, Inc.
Head and Neck Cancer, Radiation Dermatitis
Study of KeraStat Cream for Radiation Dermatitis During Head and Neck Radiotherapy
This is a single site, randomized, open-label comparison pilot study to assess the feasibility and effectiveness of KeraStat Cream compared with routine skin care (RSC) in managing radiotherapy-induced early adverse skin reaction…
- Trial name
- NCT04173247
- Testing
- KeraStat Cream, Routine Skin Care - Commercially Available Agents
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Wake Forest University Health Sciences
Coronary Artery Disease
Role of On-site CT-derived FFR in the Management of Suspect CAD Patients
The primary of this registry is to evaluate whether the availability of CTA/CT-FFR procedure could effectively optimize the flow of clinical practice of stable chest pain versus conventional clinical pathway in decision making…
- Trial name
- TARGET (NCT03901326)
- Testing
- CT-FFR assessment
- Where
- China
- Volunteers
- 1,216 people
- Sponsor
- Chinese PLA General Hospital
Aspiration, Laryngeal Cancer
NewBreez for Airway Protection in Head and Neck Cancer Patients With Chronic Aspiration
Laryngeal dysfunction is a problem that affects many patients after laryngeal cancer therapy (surgery or radio/chemotherapy). Laryngeal dysfunction is associated with higher incidences of aspiration and respiratory tract…
- Trial name
- NCT02437513
- Testing
- NewBreez
- Volunteers
- 2 people
- Sponsor
- ProTiP Medical
Asthma
A Pilot and Feasibility Study of Mobile-Based Asthma Action Plans
Investigators from University of Arkansas for Medical Sciences Department of Pediatrics and University of Arkansas for Medical Sciences Center for Distance Health will collaborate to develop a mobile-based Asthma Action Plan…
- Trial name
- NCT01514760
- Testing
- Mobile-based Asthma Action Plan
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Critical Illness, Sleep Deprivation
Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients
The goal of this project is to determine whether the sleep and circadian rhythms of critically ill patients undergoing mechanical ventilation can be improved through practical strategies that can be employed at the bedside.
- Conditions
- Critical Illness, Sleep Deprivation, Respiratory Failure, Sleep Disorders, Circadian Rhythm
- Trial name
- NCT01284140
- Testing
- Sleep and circadian rhythm promotion, Usual care
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- Brian Gehlbach
Serious Injury, Communication
A Communication Tool to Improve Communication in the ICU
The purpose of this study is to test the effectiveness of the Best Case/Worst Case-ICU communication tool on quality of communication, clinician moral distress, and ICU length of stay for older adults with serious traumatic…
- Trial name
- NCT05780918
- Testing
- Best Case/Worst Case-ICU Communication Tool
- Where
- 8 sites in United States
- Volunteers
- 7,320 people
- Sponsor
- University of Wisconsin, Madison
Neurological Disorder, Autoimmune Diseases
Disease-Modifying Treatments for Myasthenia Gravis
This study is designed to address the evidence gaps in a real-world setting and help patients with MG choose treatments that are best suited to them.
- Trial name
- PROMISE-MG (NCT03490539)
- Testing
- Mycophenolate Mofetil, Azathioprine
- Where
- 19 sites in United States, Canada
- Volunteers
- 82 people
- Sponsor
- Duke University
HIV Infections
Long-Acting Cabotegravir Plus VRC-HIVMAB075-00-AB (VRC07-523LS) for Viral Suppression in Adults Living With HIV-1
The purpose of this study was to assess the safety, tolerability, antiviral activity, and pharmacokinetics of long-acting cabotegravir (CAB LA) plus the broadly neutralizing monoclonal antibody VRC-HIVMAB075-00-AB (VRC07-523LS)…
- Trial name
- NCT03739996
- Testing
- Oral Cabotegravir (CAB), Nucleoside Reverse Transcriptase Inhibitors (NRTIs), Long-Acting Injectable Cabotegravir (CAB LA)
- Where
- 18 sites in United States, Puerto Rico
- Volunteers
- 75 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Airway Obstruction, Apnea
Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy
The primary goal of this study is to determine the effectiveness and safety of delivering continuous negative external pressure (cNEP) to the upper airway as a means of preventing episodes of respiratory impairment (RI) such as…
- Conditions
- Airway Obstruction, Apnea, Hypopnea
- Trial name
- NCT01895062
- Testing
- Airway Management System (AMS)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- 5i Sciences, Inc.
Relapsed/Refractory Multiple Myeloma
NINLARO Capsules Drug Use-Results Survey (All-Case Surveillance) "Relapsed/Refractory Multiple Myeloma"
The purpose of this study is to evaluate the safety of NINLARO in participants with relapsed/refractory multiple myeloma in daily clinical practice.
- Trial name
- NCT03169361
- Testing
- Ixazomib
- Where
- Japan
- Volunteers
- 774 people
- Sponsor
- Takeda
Concept Mapping Versus Interviews
Concept Mapping as a Scalable Method for Identifying Patient-Important Outcomes
The goal of this study is to improve the methods with which researchers identify patient centered outcomes for use in research. Specifically, the investigators will test the application of concept mapping as compared to…
- Trial name
- VOICe (NCT02792777)
- Testing
- Interviews, Concept Mapping (CM)
- Where
- United States
- Volunteers
- 148 people
- Sponsor
- Thomas Jefferson University
Heart Disease (Coronary Artery Disease, Ischemic Heart Disease, Hypertensive Heart Disease), Uncontrolled Diabetes (HBA1c ≥ 10)
Piloting the IPROACTIF Program to Preserve Functioning and Prevent Cognitive Decline
Conduct a pilot randomized control to assess the preliminary efficacy of IPROACTIF, an occupational therapist-delivered primary care intervention for aging and chronic disease management.
- Trial name
- NCT04682977
- Testing
- IPROACTIF (Integrated PRimary Care and Occupational Therapy for Aging and Chronic Disease Treatment to preserve Independence and Functioning), Usual primary care services
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Illinois Chicago