Clinical trials: Routine care, completed
Critical Illness, Intensive Care
Early Exercise Training in Critically Ill Patients
This randomized controlled trial was designed to investigate whether a daily training session using a bedside cycle ergometer, started early in stable critically ill patients with an expected prolonged ICU stay, could induce a…
- Conditions
- Critical Illness, Intensive Care, Muscle Weakness, Deconditioning
- Trial name
- NCT00695383
- Testing
- Bedside cycle exercise therapy, Standard physiotherapy program
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Acute Myeloid Leukemia
Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML)
This study will test daily dosing of atovaquone at established pneumocystis jiroveci pneumonia (PJP) prophylaxis dosing in combination with standard induction chemotherapy for de novo AML.
- Trial name
- ATACC AML (NCT03568994)
- Testing
- Atovaquone, Cytarabine, Daunorubicin
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Baylor College of Medicine
Retinoblastoma
Feasibility of Generating Pluripotent Stem Cells From Patients With Familial Retinoblastoma
The goal of this study is to determine if human RB1-deficient induced pluripotent stem cells (iPSCs) can produce retina, and, furthermore, can give rise to retinoblastoma in culture.
- Trial name
- NCT02193724
- Testing
- Skin Biopsy, Blood Draw
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Jude Children's Research Hospital
Diet Habit
Women's Health Food Frequency Questionnaire
The aim of this study is to develop a tool that can measure the iron, folate, and vitamin B12 content of a diet through a literature review, database search, and a pilot study using a food consumption record.
- Trial name
- NCT05843942
- Testing
- Questionnaire
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Hacettepe University
Congenital Heart Disease
Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery
Neonates, children with single ventricle congenital heart disease, and those undergoing multiple complex cardiac surgeries are at high risk of increased perioperative blood loss, and blood product transfusions.
- Trial name
- NCT02410473
- Testing
- Discarded blood samples, Discarded Urine Sample
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Chronic Disease, Quality of Life
Electronic Patient Reported Outcome (ePRO) Mobile Application Pragmatic Trial
Canadian and international health care systems require solutions on how to address the needs of a relatively small population that take up a large portion of health care resources.
- Trial name
- NCT02917954
- Testing
- ePRO Tool Intervention
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Anxiety Disorder in Conditions Classified Elsewhere
A Mindfulness-based Intervention for Treatment of Anxiety in ICD (Implantable Cardioverter Defibrillator) Patients
The purpose of this study is to evaluate the feasibility and preliminary efficacy of a mindfulness-based behavioral intervention combining breathing and other relaxation exercises on symptoms of anxiety in patients undergoing the…
- Trial name
- NCT01035294
- Testing
- mindfulness based intervention (MBI), usual care
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Massachusetts, Worcester
Acute Respiratory Failure
Impact of Dyspnea, Regional Lung Ventilation, and Diaphragmatic Function During de Novo Acute Respiratory Failure
Modern management of acute respiratory failure aims to relieve dyspnea and anxiety by providing a non-invasive respiratory support.
- Trial name
- DY-VI-DI (NCT04961437)
- Testing
- Diaphragmatic ultrasound and electrical impedance tomography
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Premature Infants
Shorten the Time Required to Correct the Arrival of Complete Oral Feeding in Premature Infants
Non-nutritive sucking combined with a step-by-step oral feeding regimen shortens the total oral feeding cycle in premature infants
- Trial name
- NCT05208437
- Testing
- Complete oral feeding intervention, Routine nursing care group
- Where
- China
- Volunteers
- 148 people
- Sponsor
- Children's Hospital of Fudan University
Chronic Obstructive Pulmonary Disease
Outcomes in Real-life After Initation of Treatment With Trixeo (Budesonide / Glycopyrronium / Formoterol)
The aim of the CHOROS ORION study is to describe patients' clinical and self-reported outcomes of treatment with BGF in Italy through effectiveness, clinical and self-reported measures assessed pre- and post-treatment initiation…
- Trial name
- CHOROS ORION (NCT05862545)
- Testing
- BGF (budesonide/glycopyrrolate/formoterol fumarate)
- Where
- 20 sites in Italy
- Volunteers
- 250 people
- Sponsor
- AstraZeneca
Development, Child
Sit Down and Play India
To gather data essential to evaluate the acceptability and feasibility of a brief, health care-based program delivered in routine healthcare visits in low and low-middle income countries to promote positive parenting behaviors…
- Trial name
- NCT04167254
- Testing
- Sit Down and Play
- Where
- 2 sites in United States, India
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Pain
The Effect of Dance and Massage Applied by Partners at Birth on Birth Pain, Comfort and Satisfaction
Pregnancy and the moment of birth are important processes that women will remember throughout their lives and will always leave a mark on their lives.
- Trial name
- NCT06179966
- Testing
- Dance group, Massage group
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Kırklareli University
Heart Failure
Characterizing Guideline Adoption and Treatment Quality in Clinical Routine of German HFrEF Care
This was a multicenter, non-randomized, non-interventional cohort study with prospective and retrospective collection of primary data on heart failure with reduced ejection fraction (HFrEF) patient treatment and care following a…
- Trial name
- CONNECT (NCT06004453)
- Testing
- Heart Failure medications
- Where
- 94 sites in Germany
- Volunteers
- 899 people
- Sponsor
- Novartis Pharmaceuticals
Depression, Postpartum
The Effect of Yoga Applied to Primiparous Pregnant Women on Postpartum Depression and Maternal Attachment
This randomized controlled trial aims to evaluate the effects of an 8-week prenatal yoga intervention on postpartum depression and maternal attachment among primiparous pregnant women.
- Trial name
- NCT07583095
- Testing
- prenatal yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Muş Alparslan University
High Risk Pregnancy, Cesarean Section
Education of Pregnant Women With a Prenatal Indication for Cesarean Section Through Periodic Short Message Service (SMS) and Interactive Voice Response System (IVR) in Uganda
Women with antenatally identified indications for planned pre-labor cesarean delivery in low-resource settings frequently present in labor before their scheduled delivery, resulting in emergency cesarean delivery and increased…
- Trial name
- NCT07696325
- Testing
- SMS and Interactive Voice Response (IVR) Educational Intervention
- Where
- Uganda
- Volunteers
- 71 people
- Sponsor
- Massachusetts General Hospital
HIV, Opioid Dependence
Testing a Community-Friendly Risk Reduction Intervention for Injection Drug Users
To conduct a randomized clinical trial (RCT) of a community-friendly behavioral intervention designed to reduce HIV risk behavior among injection drug users (IDUs) in drug treatment by comparing risk-behavior outcomes of four…
- Trial name
- NCT01741350
- Testing
- Community-friendly Health Recovery Program, Time-and-Attention-Matched Control Condition
- Where
- United States
- Volunteers
- 304 people
- Sponsor
- University of Connecticut
Chronic Kidney Failure, End-Stage Renal Disease
Effect of Isometric Hand Grip Exercises Using a Dynamometer on AV Fistula Maturation and Patency in Hemodialysis Patients
Patients with chronic kidney failure who require hemodialysis depend on a surgically created connection between an artery and a vein in the arm, known as an arteriovenous fistula.
- Conditions
- Chronic Kidney Failure, End-Stage Renal Disease, Arteriovenous Fistula
- Trial name
- NCT07238855
- Testing
- Isometric Hand-Grip Exercise Training Using a Hand Dynamometer
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Mansoura University
Neonatal Thrombocytopenia, Intraventricular Hemorrhage
PRedicting OutcomeS in Preterm nEonates With thromboCyTopenia
Preterm neonates often receive platelet transfusions when their platelet count is low to prevent bleeding. However, it is currently unclear which infants benefit from such transfusions.
- Conditions
- Neonatal Thrombocytopenia, Intraventricular Hemorrhage, Platelet Transfusion
- Trial name
- PROSPECT (NCT06043050)
- Testing
- Platelets
- Where
- 12 sites in Germany, Netherlands and 1 more
- Volunteers
- 1,042 people
- Sponsor
- Leiden University Medical Center
Neuromuscular Diseases in Infants, Neuromuscular Diseases in Children
Study of the Correlation Between Muscle Oxygenation and Motor Function in Children With Neuromuscular Disease.
Preliminary data underline the fact that muscular deoxygenation during training happens earlier in adult patients suffering from neuromuscular disorders in comparison to controls. Up to date, pediatric data are lacking.
- Trial name
- OXMNM (NCT03471676)
- Testing
- Muscular oximetry
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Tours
RUSH Protocol
Routine Use of RUSH Protocol in the Intensive Care Unit
The RUSH protocol has been used for several years for the rapid evaluation of a patient admitted to the emergency room with shock.
- Trial name
- NCT06361225
- Testing
- evaluation with RUSH protocol
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
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