Clinical trials: Routine care
Critical Illness, Intensive Care
Early Exercise Training in Critically Ill Patients
This randomized controlled trial was designed to investigate whether a daily training session using a bedside cycle ergometer, started early in stable critically ill patients with an expected prolonged ICU stay, could induce a…
- Conditions
- Critical Illness, Intensive Care, Muscle Weakness, Deconditioning
- Trial name
- NCT00695383
- Testing
- Bedside cycle exercise therapy, Standard physiotherapy program
- Where
- Belgium
- Volunteers
- 90 people
- Sponsor
- KU Leuven
Acute Myeloid Leukemia
Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML)
This study will test daily dosing of atovaquone at established pneumocystis jiroveci pneumonia (PJP) prophylaxis dosing in combination with standard induction chemotherapy for de novo AML.
- Trial name
- ATACC AML (NCT03568994)
- Testing
- Atovaquone, Cytarabine, Daunorubicin
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Baylor College of Medicine
Pediatric, Neuropathic Pain
Amputations in Childhood and Neuropathic Pain
This observational study aims to assess the presence of neuropathic pain in children and adolescents who underwent limb amputation during childhood.
- Conditions
- Pediatric, Neuropathic Pain, Phantom Limb Pain, Amputation
- Trial name
- NAPE (NCT07401966)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hopitaux de Saint-Maurice
Asphyxia Neonatorum, Fetal Hypoxia
Sustained Cord Circulation at Emergency Cesarean Section
The goal of this clinical trial is to evaluate if sustained cord circulation during resuscitation improves outcomes for term neonates born by emergency Cesarean section.
- Trial name
- SUCCECS (NCT06540222)
- Testing
- Sustained cord (≥ 180 seconds) resuscitation, Routine (< 60 seconds) cord clamping
- Where
- 12 sites in Sweden
- Volunteers
- 2,200 people
- Sponsor
- Region Skane
Retinoblastoma
Feasibility of Generating Pluripotent Stem Cells From Patients With Familial Retinoblastoma
The goal of this study is to determine if human RB1-deficient induced pluripotent stem cells (iPSCs) can produce retina, and, furthermore, can give rise to retinoblastoma in culture.
- Trial name
- NCT02193724
- Testing
- Skin Biopsy, Blood Draw
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Jude Children's Research Hospital
Diet Habit
Women's Health Food Frequency Questionnaire
The aim of this study is to develop a tool that can measure the iron, folate, and vitamin B12 content of a diet through a literature review, database search, and a pilot study using a food consumption record.
- Trial name
- NCT05843942
- Testing
- Questionnaire
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 450 people
- Sponsor
- Hacettepe University
Empathy, Anxiety
Psychosocial Effects of Empathy-Based Midwifery Education on Midwifery Students and Pregnant Women
This two-stage quasi-experimental study will evaluate the effects of empathy-based midwifery education on midwifery students' empathy and anxiety, and on women's satisfaction with childbirth and perceptions of traumatic birth.
- Conditions
- Empathy, Anxiety, Childbirth
- Trial name
- PEEBMEMSPW (NCT07889986)
- Testing
- Empathy-Based Midwifery Education, Empathy-Based Midwifery Support During Labor
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Congenital Heart Disease
Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery
Neonates, children with single ventricle congenital heart disease, and those undergoing multiple complex cardiac surgeries are at high risk of increased perioperative blood loss, and blood product transfusions.
- Trial name
- NCT02410473
- Testing
- Discarded blood samples, Discarded Urine Sample
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Boston Children's Hospital
Chronic Disease, Quality of Life
Electronic Patient Reported Outcome (ePRO) Mobile Application Pragmatic Trial
Canadian and international health care systems require solutions on how to address the needs of a relatively small population that take up a large portion of health care resources.
- Trial name
- NCT02917954
- Testing
- ePRO Tool Intervention
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Intellectual Disability, Variable
A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities
This randomized clinical trial is an innovative pilot project to determine the acceptance and impact of telehealth visits on youth with intellectual and developmental disabilities (IDD), their caregivers, and dentists.
- Trial name
- NCT06710483
- Testing
- Pre-Dental Telehealth (PDT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Delirium Confusional State
Exploring the Effectiveness of Intelligent Audiovisual Interventions in Delirium, Agitation, and Pain Among Middle Aged and Elderly Patients in Emergency Intensive Care Units: A Quasi-Experimental Study
The goal of this nonrandomized, quasi-experimental clinical trial is to evaluate whether an intelligent audiovisual intervention can prevent delirium and reduce delirium severity, agitation, and pain among adults aged 55 years or…
- Trial name
- NCT07776002
- Testing
- Intelligent Audiovisual Intervention
- Volunteers
- 128 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Hypoxemia
Extubation Safety Via Microstream EtCO₂ (IPI) Monitoring
The goal of this clinical trial is to evaluate whether extubation guided by the Integrated Pulmonary Index (IPI)-a composite respiratory score derived from microstream sidestream end-tidal carbon dioxide (EtCO₂)…
- Trial name
- NCT06975553
- Testing
- endotracheal intubation-type end-tidal carbon dioxide sampling tube
- Where
- China
- Volunteers
- 632 people
- Sponsor
- Chinese PLA General Hospital
Colo-rectal Cancer, Liver Metastases
Radiogenomic Profiling of Dendritic Cells and Macrophages to Predict Recurrence in Colorectal Liver Metastasis
The RaP-DMac-LiMe study (Radiogenomic Profiling of Dendritic Cells and Macrophages to Predict Recurrence in Colorectal Liver Metastasis) is a monocentric, non-profit observational study promoted by Fondazione Policlinico…
- Conditions
- Colo-rectal Cancer, Liver Metastases, Colon Cancer
- Trial name
- RaP-DMac-LiMe (NCT07744139)
- Testing
- Radiogenomic and Immune Profiling, Prospective Radiogenomic and ctDNA Profiling
- Volunteers
- 210 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
B Cell Lymphoma, Multiple Mieloma
Immunomonitoring and Predictive Biomarkers After CAR-T Cell Therapy in B-Cell Lymphoma and Multiple Myeloma
CARBIOM is a single-centre, non-randomized interventional study involving additional biological sampling with minimal risks and constraints.
- Trial name
- CARBIOM (NCT07852377)
- Testing
- Biological sample collection and immunomonitoring
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Henri Becquerel
Postoperative Pain
Clinical Pharmacist-Led Perioperative Pain Management in Orthopedic Surgery: An Effectiveness Evaluation
This study aims to evaluate the effectiveness of a clinical pharmacist-led perioperative pain management model in orthopedic surgery. It is a randomized controlled trial involving patients undergoing major orthopedic procedures.
- Trial name
- NCT07688486
- Testing
- Clinical Pharmacist-Led Pain Management, Standard Perioperative Care
- Volunteers
- 600 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion
Study to Learn More About the Safety and Effectiveness of the Drug VITRAKVI During Routine Use in Patients With TRK Fusion Cancer Which is Locally Advanced or Spread From the Place Where it Started to Other Places in the Body
In this observational study researcher want to learn more about the effectiveness of drug VITRAKVI (generic name: larotrectinib) and how well the drug is tolerated during routine use in patients with TRK fusion cancer which is…
- Trial name
- ON-TRK (NCT04142437)
- Testing
- larotrectinib(Vitrakvi, BAY2757556)
- Where
- 47 sites in United States, Argentina and 13 more
- Volunteers
- 54 people
- Sponsor
- Bayer
Knee Prosthesis
Effect of Normothermia Care Bundle in Knee Replacement Surgery
Osteoarthritis is a disease characterized by disruption of the integrity of articular cartilage as a result of erosion of articular cartilage.
- Trial name
- NCT06454877
- Testing
- active heating, pasive heating
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Lesional Coma
Imaging of the Neural Correlates of Arousal and Awareness
In last decades, several advances in the neuro-intensive management have lead to decrease mortality in Intensive Care Units. A significant morbidity remains as patients survive after a traumatic coma with uncertain quality of…
- Trial name
- IMAGINA (NCT04575454)
- Testing
- Multimodal evaluation of brain function : PET-MRI, electrophysiology, eye-tracking
- Where
- France
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Anxiety Disorder in Conditions Classified Elsewhere
A Mindfulness-based Intervention for Treatment of Anxiety in ICD (Implantable Cardioverter Defibrillator) Patients
The purpose of this study is to evaluate the feasibility and preliminary efficacy of a mindfulness-based behavioral intervention combining breathing and other relaxation exercises on symptoms of anxiety in patients undergoing the…
- Trial name
- NCT01035294
- Testing
- mindfulness based intervention (MBI), usual care
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Massachusetts, Worcester
Breast Neoplasms, Breast Cancer
IRELAND Trial: A Translational Biomarker and Exercise Study During Neoadjuvant Breast Cancer Therapy
The goal of this clinical trial is to learn whether a physiotherapy-led exercise programme delivered during treatment before surgery (neoadjuvant therapy) for breast cancer can improve physical fitness, quality of life, and how…
- Trial name
- IRELAND (NCT07799337)
- Testing
- Physiotherapist-Led Personalised Adaptive Exercise Programme
- Volunteers
- 250 people
- Sponsor
- National University of Ireland, Galway, Ireland
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.