Clinical trials: Routine care
Renal Dialysis
Intervention to Reduce Dietary Sodium in Hemodialysis
The purpose of this study is to test, in a randomized clinical trial of 200 hemodialysis patients, a behavioral intervention to reduce dietary sodium intake.
- Trial name
- BalanceWise-HD (NCT01125202)
- Testing
- SCT-based behavioral intervention, Attention Control
- Where
- United States
- Volunteers
- 179 people
- Sponsor
- University of Pittsburgh
Suicide
Adolescent and Child Suicide Prevention in Routine Clinical Encounters
The objective of this study is to compare two approaches to implement an evidence-based firearm safety promotion program, S.A.F.E. Firearm, in pediatric primary care as a universal suicide prevention strategy.
- Trial name
- ASPIRE (NCT04844021)
- Testing
- Nudge, Nudge+
- Where
- 2 sites in United States
- Volunteers
- 47,307 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Surgery
EPAD Monitoring of Patients Undergoing Robotic Assisted Laparoscopic Genitourinary Surgery
Participants to be enrolled in this study will have been scheduled to have laparoscopic genitourinary surgery and EPAD monitoring as part of their clinical care intraoperatively.
- Trial name
- NCT03319407
- Testing
- EPAD monitoring system
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Mayo Clinic
PreDiabetes, Prediabetic State
Implementation and Evaluation of a Diabetes Prevention Clinical Pathway in Primary Care
Prediabetes is a significant public health problem affecting 88 million U.S. adults. Evidence suggest that the vast majority of people with prediabetes are unaware of having this condition and many are not receiving appropriate…
- Trial name
- NCT05265312
- Testing
- START diabetes prevention clinical pathway
- Where
- United States
- Volunteers
- 1,910 people
- Sponsor
- Johns Hopkins University
Maternal Substance Use, Child Abuse and Neglect
Stage I Randomized Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers
The primary goal of this Stage I therapy development study will be to manualize and test the preliminary efficacy of a parenting intervention for drug dependent mothers that aims to foster their ability to recognize children's…
- Trial name
- NCT00319436
- Testing
- Mentalizing Therapy for Substance Using Mothers, Standard Parent Education for Substance Using Mothers
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Yale University
Dental Caries in Children, Health Behavior
Coordinated Oral Health Promotion (CO-OP) Chicago
This study assesses the impact of oral health promotion delivered by community health workers in medical clinics, Women, Infants and Children (WIC) centers, and family homes.
- Conditions
- Dental Caries in Children, Health Behavior, Healthcare Disparities
- Trial name
- NCT03397589
- Testing
- Community Health Worker (CHW) services
- Where
- 13 sites in United States
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Persian Gulf Syndrome, Chronic Sinusitis
Gulf War Illness Nasal Irrigation Study
The purpose of this study is to determine whether nasal irrigation with Xylitol or saline are effective in the treatment of chronic rhinosinusitis and fatigue symptoms associated with Gulf War Illness.
- Conditions
- Persian Gulf Syndrome, Chronic Sinusitis, Fatigue, Acute Sinusitis
- Trial name
- GWINIS (NCT01700725)
- Testing
- Nasal Irrigation - Saline, Nasal Irrigation - Xylitol
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Wisconsin, Madison
Post Cystostomy
Oral Nutrition After Regular Radical Cystectomy
After radical cystectomy, postoperative ileus (POI) is a common complication resulting in a delayed oral nutritional intake with prolonged recovery and hospital stay.
- Trial name
- ONP (NCT01777126)
- Testing
- Oral Nutrition Protocol (ONP) group, Control group
- Where
- Belgium
- Volunteers
- 94 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Sars-CoV2, Acute Respiratory Distress Syndrome
Mesenchymal Stromal Cells for the Treatment of SARS-CoV-2 Induced Acute Respiratory Failure (COVID-19 Disease)
*At this time, we are only enrolling at Houston Methodist Hospital (HMH)/Baylor College of Medicine (BCM) and are not shipping cells outside of BCM/HMH.* This is a study for patients who have respiratory infection caused by…
- Conditions
- Sars-CoV2, Acute Respiratory Distress Syndrome, COVID-19
- Trial name
- NCT04345601
- Testing
- Mesenchymal Stromal Cells, Supportive Care
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Baylor College of Medicine
Neurological Disorder, Autoimmune Diseases
Disease-Modifying Treatments for Myasthenia Gravis
This study is designed to address the evidence gaps in a real-world setting and help patients with MG choose treatments that are best suited to them.
- Trial name
- PROMISE-MG (NCT03490539)
- Testing
- Mycophenolate Mofetil, Azathioprine
- Where
- 19 sites in United States, Canada
- Volunteers
- 82 people
- Sponsor
- Duke University
Type 2 Diabetes
Computer Automation for Diagnosis and Management of Childhood Type 2 Diabetes
Increasing rates of type 2 diabetes among children and adolescents has considerable long-term implications not only for the affected individuals, but also for society and the health system as a whole.
- Trial name
- NCT01814787
- Testing
- CHICA Type 2 Diabetes Module
- Where
- United States
- Volunteers
- 1,369 people
- Sponsor
- Indiana University
Endometritis
Reduction of Endometritis After Cesarean Section With the Routine Use of Methergine
Endomyometritis is an "infection in the uterus". It can occur in up to 1 out of 5 women having unplanned cesarean deliveries. Antibiotics are routinely given at the time of Cesarean delivery, but the infection in the uterus can…
- Trial name
- NCT00858832
- Testing
- Methergine
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Obesity, Adolescent, Health Behavior
Health Literacy and Obesogenic Behaviors
The prevalence of adolescent behaviors that can lead to obesity are alarming, and reduced life expectancy is the future of America's youth if behavioral changes are not implemented to improve health and reduce the obesity burden.
- Conditions
- Obesity, Adolescent, Health Behavior, Health Knowledge, Attitudes, Practice, Diet, Healthy
- Trial name
- HL-Squared (NCT04252677)
- Testing
- Obesity Prevention, Health Literacy
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- City University of New York, School of Public Health
Rib Fracture, Rib Fracture Multiple
Orthosis of Acute Traumatic Rib Fractures Via RibFx Belt for Pain Alleviation and Improved Pulmonary Function
Acute traumatic rib fractures are a common issue for patients of trauma surgeons. They inflict substantial morbidity, the most dreaded and consequential of which are pulmonary complications.
- Conditions
- Rib Fracture, Rib Fracture Multiple, Trauma, Trauma Chest
- Trial name
- RibFx (NCT03846024)
- Testing
- RibFx Orthosis Belt
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Vermont Medical Center
Central Line Associated Bloodstream Infections (CLABSI), Bone Marrow Transplant
Parafilm to Prevent CLABSI in Pediatric Patients Undergoing HCT
The purpose of this study is to see if applying parafilm as an external barrier on the central line in children having a bone marrow transplant helps to prevent central line associated bloodstream infection(s) and also to assess…
- Trial name
- NCT02575079
- Testing
- Parafilm
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- Emory University
Mechanical Ventilation, Single-lung Ventilation
Assessment of the Capability of PulmoVista 500 to Continuously Monitor Changes of Ventilation Over Time
The results of this study will help to define the capability and reliability of PulmoVista 500 to detect changes in both global and regional ventilation.
- Conditions
- Mechanical Ventilation, Single-lung Ventilation, ARDS, ALI - Acute Lung Injury
- Trial name
- NCT03076983
- Testing
- Lung Monitoring with EIT device (PulmoVista 500)
- Where
- 3 sites in Germany
- Volunteers
- 80 people
- Sponsor
- Drägerwerk AG & Co. KGaA
Colorectal Cancer, Social Determinants of Health
Paired Promotion of Colorectal Cancer and Social Determinants of Health Screening
This work is an implementation science study that examines different aspects of implementing a single intervention. The intervention consists of asking community health centers to implement an outreach strategy to screen patients…
- Trial name
- NCT04585919
- Testing
- Paired Screening Intervention
- Where
- 4 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
ACL Tear
Effects of Blood Flow Restriction Rehabilitation After Anterior Cruciate Ligament Reconstruction
The study is a prospective randomized control trial consisting of subjects requiring ACL reconstruction with BTB autograft. Subjects were randomly divided into two groups following their inclusion in the study.
- Trial name
- NCT04484961
- Testing
- Blood flow restriction (BFR)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Tobacco Use Cessation
Telephone Counseling for Tobacco Cessation
The purpose of this study is to determine whether giving more structured information to patients over the phone about quitting tobacco helps to increase the chance that they will try to quit.
- Trial name
- NCT01489579
- Testing
- Telephone Counseling for Tobacco Cessation, Usual Care
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Frailty, Disability or Chronic Disease Leading to Disablement
Implementing 3-Step Workout for Life in Home Health
The purpose of this project is to study how to adapt and implement the 3-Step Workout for Life program in a local home health agency. A series of learning cycles will be conducted to adjust the treatment dose and delivery mode.
- Trial name
- NCT04709783
- Testing
- 3-Step Workout for Life
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Florida