Clinical trials: Routine care
Neonatal Thrombocytopenia, Intraventricular Hemorrhage
PRedicting OutcomeS in Preterm nEonates With thromboCyTopenia
Preterm neonates often receive platelet transfusions when their platelet count is low to prevent bleeding. However, it is currently unclear which infants benefit from such transfusions.
- Conditions
- Neonatal Thrombocytopenia, Intraventricular Hemorrhage, Platelet Transfusion
- Trial name
- PROSPECT (NCT06043050)
- Testing
- Platelets
- Where
- 12 sites in Germany, Netherlands and 1 more
- Volunteers
- 1,042 people
- Sponsor
- Leiden University Medical Center
Atrial Fibrillation
The Effectiveness of Patch-Based Screening for Pre-Symptomatic Atrial Fibrillation to Improve Patient Outcome
The goal of the screening trial is to determine whether early screening for atrial fibrillation improves outcomes, including lowering the chance of death, hospitalization for stroke, blood clots, heart failure, heart attack, and…
- Trial name
- VALIANT-AF-S (NCT06953778)
- Testing
- Zio XT® Patch
- Where
- United States
- Volunteers
- 24,060 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Neuromuscular Diseases in Infants, Neuromuscular Diseases in Children
Study of the Correlation Between Muscle Oxygenation and Motor Function in Children With Neuromuscular Disease.
Preliminary data underline the fact that muscular deoxygenation during training happens earlier in adult patients suffering from neuromuscular disorders in comparison to controls. Up to date, pediatric data are lacking.
- Trial name
- OXMNM (NCT03471676)
- Testing
- Muscular oximetry
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Tours
Hypertension, Hyperglycemia
Multimodal AI-Driven Out-of-Hospital Management for Hypertension and Cardiometabolic Risk
High blood pressure often occurs together with abnormal blood glucose, abnormal blood lipids, or abdominal obesity. Managing these conditions outside the hospital can be difficult.
- Conditions
- Hypertension, Hyperglycemia, Dyslipidemia
- Trial name
- no acronym (NCT07917676)
- Testing
- Hybrid AI-Enabled Out-of-Hospital Health Management, Standard Out-of-Hospital Guidance
- Volunteers
- 150 people
- Sponsor
- China National Center for Cardiovascular Diseases
RUSH Protocol
Routine Use of RUSH Protocol in the Intensive Care Unit
The RUSH protocol has been used for several years for the rapid evaluation of a patient admitted to the emergency room with shock.
- Trial name
- NCT06361225
- Testing
- evaluation with RUSH protocol
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Meir Medical Center
Parkinson, Parkinson Disease
Mediterranean Diet Effects on Parkinson's Disease
Currently, there are no disease-modifying treatments for Parkinson's disease (PD), the second most common neurodegenerative disorder worldwide, making it crucial to find interventions that can change the disease's trajectory.
- Conditions
- Parkinson, Parkinson Disease, Parkinson Disease, Idiopathic, PARKINSON DISEASE (Disorder)
- Trial name
- MED-PARK (NCT06705517)
- Testing
- Mediterranean Diet
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Università degli Studi dell'Insubria
Anxiety
Brief Anxiety Skills Training Intervention for Veterans in Primary Care
Anxiety symptoms are common among primary care patients, but anxiety is undertreated. Brief behavioral (non-medication) anxiety treatments are needed.
- Trial name
- NCT04829240
- Testing
- Veterans Anxiety Skills Training Intervention, PCMHI Usual Care
- Where
- 2 sites in United States
- Volunteers
- 213 people
- Sponsor
- VA Office of Research and Development
Lung Cancer
MIRA Clinical Learning Environment (MIRACLE): Lung
The goal of this quality improvement (QI) study is to develop automated clinical pipelines to implement machine learning models in the care pathway of lung cancer patients.
- Trial name
- MIRACLE (NCT05689437)
- Testing
- Application of ILD prediction machine learning model to planning imaging, Routine, automatic presentation of ILD risk level for evaluation by the clinician., Application of SGR machine learning model to diagnostic and planning imaging
- Where
- Canada
- Volunteers
- 1,000 people
- Sponsor
- University Health Network, Toronto
Colorectal Cancer, Colorectal Neoplasms
PRIORITY-CONNECT 2 Trial
Objectives: The primary aim of this project is to establish the effectiveness of an individualised stepped, multidisciplinary intervention, including education and peer support group, delivered via a virtual multimodal…
- Trial name
- PC2 (NCT06976710)
- Testing
- Preoperative Exercise, Postoperative Exercise, Preoperative Nutrition
- Where
- 31 sites in Australia
- Volunteers
- 564 people
- Sponsor
- Surgical Outcomes Research Centre (SOuRCe)
Blood Collection
Use of Hand Puppets and Image Watching and Coloring Books for Children in During Blood Collection Procedures
The aim of this study was to compare a hand puppet with image viewing and a coloring book for children in reducing children's pain and fear during blood collection.
- Trial name
- NCT07044713
- Testing
- Hand Puppet, The Visual Viewing and Coloring Book
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Artvin Coruh University
Heart Failure
Multidisciplinary Approach for High Risk Patients Leading to Early Diagnosis of Canadians in Heart Failure
The goal of this study is improve the screening of heart failure and identify patients early who are at risk of heart failure. The main question[s] it aims to answer are: will an electronic health records (EHR) case finding…
- Trial name
- MAPLE-CHF (NCT05859048)
- Testing
- NT-proBNP, AI echocardiogram, electrocardiogram
- Where
- 3 sites in Canada
- Volunteers
- 1,360 people
- Sponsor
- Cardiology Research UBC
Decision Making, Chromosome Abnormality
Efficacy of Counseling for Prenatal Screening and Diagnostic Tests on Pregnant Women: Randomised Controlled Study
The aim of this study was to evaluate the effect of counseling for prenatal screening and diagnostic tests on pregnant women's decisional conflict, being sure of the decision, anxiety levels, and attitudes towards the tests.
- Conditions
- Decision Making, Chromosome Abnormality, Anxiety, Knowledge, Attitudes, Practice
- Trial name
- NCT03825978
- Testing
- Prenatal Genetic Counseling
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Rejuvenation, Lifting Efficacy
Efficacy and Safety of a Novel Monopolar Radiofrequency Device for Mid and Lower Face Rejuvenation
The aim of this study is to evaluate the efficacy and safety of mid- and lower-face lifting and contouring treatments using the novel monopolar radiofrequency device, NeoSculpt.
- Conditions
- Rejuvenation, Lifting Efficacy, Medical Devices
- Trial name
- NCT07590843
- Testing
- NeoSculpt
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Gynecologic Nursing
Effect of Music On Pain and Anxiety Paddle Edometrial Biopsy
This study was conducted as a randomized controlled trial to investigate the effect of music recital on pain and anxiety in women undergoing pipelined endometrial biopsy.
- Trial name
- NCT06659133
- Testing
- Music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Adiyaman University Research Hospital
Exposure, Cardiopulmonary
Firefighter Collaborative Research Project
The goal of this research is to test interventions to reduce firefighter cardiovascular, cognitive, and overall disease risks, including but not limited to risks associated with Per- and Polyfluorinated Substances (PFAS)…
- Trial name
- FCRP (NCT05869747)
- Testing
- Blood Donation, Plasma Donation, Zone 2 Training
- Where
- 7 sites in United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Auricular Acupressure, Episiotomy Pain
Effects of Auricular Acupressure on Relieving Pain in Postpartum Women With Episiotomy
This randomized, single-blind controlled trial examined the effects of auricular acupressure on postpartum women who underwent episiotomy.
- Trial name
- NCT07277478
- Testing
- auricular patch
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- HSIAO AI WEN
Pancreatic Neoplasms
Pancreas Volume and Diabetes Status Following Pancreatectomy
This study will enroll 100 patients scheduled to undergo a pancreatectomy. The primary objective is to develop a scoring system using pancreatic volume measured by CT scan and intraoperative measurements of the pancreas…
- Trial name
- NCT02823678
- Testing
- Pancreatectomy
- Volunteers
- 100 people
- Sponsor
- Florida Hospital Tampa Bay Division
Arrhythmias, Cardiac
AI Powered Mapping Technology for Identifying Arrhythmias
Exploratory, hypothesis-generating study evaluating the impact of vMap on procedural efficiency, acute success, and work flow optimization.
- Trial name
- VITAL-EP (NCT06939478)
- Testing
- Arrhythmia Mapping
- Where
- 5 sites in United States
- Volunteers
- 112 people
- Sponsor
- Heart Rhythm Clinical and Research Solutions, LLC
Nursing Caries, Pain
Effect of Music on Pain in Cancer Patients in Palliative Care Service: a Randomized Controlled Study
Background: Palliative care services can be applied in chronic, life-threatening conditions such as cancer, and provide physical, mental and psychological support to patients worldwide.
- Conditions
- Nursing Caries, Pain, Music Therapy
- Trial name
- nursingcare (NCT04486443)
- Testing
- music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- gönül düzgün
Generalized Gingivitis
The Effect of Toothpaste Containing Aloe Vera on Gingivitis
Twenty-four adult patients (male and female) with generalized gingivitis participated in the double-blinded randomized crossover trial was divided into two groups, (aloe vera and Colgate toothpaste).
- Trial name
- NCT04662385
- Testing
- aloe vera toothpaste, Colgate Total
- Where
- Iraq
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zainab J Abbas
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