Clinical trials: Sevoflurane, completed
Acute Kidney Injury, Anesthesia
The Effect of Propofol or Sevoflurane on Renal Function
This study investigates the role of the anesthetic agents propofol and sevoflurane on renal function in otherwise healthy patients undergoing basic back surgery.
- Trial name
- NCT03336801
- Testing
- Back Surgery, Propofol, Sevoflurane
- Where
- Sweden
- Volunteers
- 37 people
- Sponsor
- Uppsala University
Midazolam, Sevoflurane
Preoperative Anxiolysis With Intravenous Midazolam on Intraoperative Sevoflurane Gas Consumption
This prospective, randomized, double-blind, placebo-controlled study is performed after obtaining written informed consent of patients who are scheduled for elective general surgery.
- Trial name
- NCT05371600
- Testing
- Midazolam, Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Cukurova University
Postoperative Delirium (POD), Diabetes
Impact of Sevoflurane Versus Propofol on Postoperative Delirium in Elderly Diabetic Patients Undergoing Non-Cardiac Surgery: a Multicenter, Randomized Controlled Trial
The present study is a multicenter， randomized controlled clinical trial, which plans to enroll 450 diabetic patients aged more than 60 years.
- Trial name
- NCT06788743
- Testing
- TIVA ( anesthesia with propofol and remifentanil), VA（anesthesia with sevoflurane and remifentanil）
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Xijing Hospital
Anesthesia
Feasibility and Safety Properties of Metabolic Flow Anesthesia Driven by Automated Gas Control in Pediatric Patients
Low flow anesthesia was considered to be causing rebreathing, hypoxia and hypercarbia in the past. However, developing technologies made anesthesia ventilators safer.
- Trial name
- NCT05644340
- Testing
- Speed 8 (Fast balancing gas flow), Speed 4 (Medium speed balancing gas flow)
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Istanbul University
Deep Sedation, Anesthesia, General
Addition of Nitrous Oxide and Its Effects on Depth of Anesthesia
The study hypothesizes that adding 60% nitrous oxide to a steady state sevoflurance or propofol anesthetic will lead to a decrease in both BIS and Entropy indices during a constant level of surgical stimulus
- Trial name
- N20 (NCT00717574)
- Testing
- Sevoflurane group, Propofol group
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Oklahoma
Emergence Agitation, Anesthetics
The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty
Emergence agitation, defined as restlessness, disorientation, arousal, and/or inconsolable crying, is a common phenomenon seen in the early phase of recovery from general anesthesia; this may cause respiratory depression, nausea…
- Conditions
- Emergence Agitation, Anesthetics, Rhinoplasty
- Trial name
- NCT05601674
- Testing
- : Conventional flow Anesthesia, Low Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Inonu University
Auditory Brainstem Response
Comparative Effects of Two Anesthetic Techniques on Auditory Brain Response in Children
This will be a prospective, blinded, cross-over study to compare the effects of two anesthetic techniques on the interpretability of auditory brainstem response testing in children.
- Trial name
- NCT02830815
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Myocardial Protection
Effects of TENS on Myocardial Protection in Patients Undergoing AVR
Patients undergoing aortic valve replacement are randomized to receive TENS (transcutaneous electrical nerve stimulation) or sham stimulation at one arm for 30 min under various anesthetic conditions: no anesthesia…
- Trial name
- NCT03859115
- Testing
- TENS (transcutaneous electrical nerve stimulation)
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Seoul National University Hospital
Respiratory Complication
Optimal Effect-site Concentration of Remifentanil for Inhibiting Response to Laryngeal Mask Airway (LMA) Removal
This study was designed to determine the optimal dose of remifentanil that can prevent the complications associated with the removal of LMA without delaying emergence.
- Trial name
- NCT01915108
- Testing
- Remifentanil
- Volunteers
- 128 people
- Sponsor
- Sangjin Park
Carotid Stenosis
Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarterectomy
The aim of this study is comparing the effect on cerebral oxygenation by sevoflurane-remifentanil or propofol-remifentanil anesthesia in patient undergoing carotid endarterectomy.
- Trial name
- NCT02609087
- Testing
- Sevoflurane, Propofol
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Chonnam National University Hospital
Intracranial Aneurysms
A Better Choice for Patients Undergoing Endovascular Coil Embolization
The investigators designed a double-blind, randomized placebo-controlled study to determine the effects of dexmedetomidine on the recovery characteristics of patients who were scheduled to undergo endovascular coil embolization.
- Trial name
- NCT01722409
- Testing
- sevoflurane and 0.5 μg/kg dexmedetomidine, sevoflurane and 1 μg/kg dexmedetomidine
- Where
- China
- Volunteers
- 64 people
- Sponsor
- China Medical University, China
Opioid Use, Postoperative Pain
Opioid Free Anesthesia and Major Spine Surgery
This study compares the intraoperative opioid free anesthesia approach in multilevel spine posterior instrumentation surgery to a conventional opioid-based anesthesia.
- Conditions
- Opioid Use, Postoperative Pain, Spine Disease
- Trial name
- NCT03417193
- Testing
- opioid free Anesthesia vs Opioid based Anesthesia
- Where
- Lebanon
- Volunteers
- 48 people
- Sponsor
- Lebanese American University
Anaesthesia
Study of Anaesthesia Costs and Recovery Profiles
The purpose of this study is to compare the perioperative hemodynamic parameters, recovery profiles and cost containment of sevoflurane and propofol based general anesthesia for otorhinolaryngeal surgery.
- Trial name
- SACRP (NCT02920749)
- Testing
- Sevoflurane group A, Sevoflurane group B, Propofol group C
- Where
- Hungary
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Brain Cancer
Sugammadex Given for the Reversal of Rocuronium Induced Neuromuscular Blockade Under Sevoflurane Anesthesia in Infants
The objective of this study is to evaluate the efficacy and safety of sugammadex in reversing profound neuromuscular block induced by rocuronium in infant patients
- Trial name
- NCT02708056
- Testing
- Sugammadex
- Volunteers
- 26 people
- Sponsor
- Baskent University
Anesthesia, General
Evaluation of Volatile Induction and Maintenance Anesthesia (VIMA) With Sevorane in Adult Patients Requiring General Anesthesia for Surgery in Terms of Quality of Anesthesia and Its Influence on the Cardiovascular System in Common Clinical Practice
The main objective of this post-marketing observational study (PMOS) is to collect data of using general anesthesia in patients undergoing any surgery to create local recommendations.
- Trial name
- SEVOPROTECTION (NCT01282086)
- Where
- 10 sites in Ukraine
- Volunteers
- 1,365 people
- Sponsor
- Abbott (Ukraine)
Postoperative Pain
Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical Mastectomy
The aim of this study is to Investigate the analgesic efficacy of adding ketamine compared to neostigmine to local anesthetic in Ultrasound guided Serratus anterior plane block for patients undergoing Modified Radical Mastectomy.
- Trial name
- NCT04544228
- Testing
- Serratus Anterior Plane Block Technique, General anesthesia, bupivacaine +ketamine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Intraoperative Hypotension
Bispectral Index Guided Sevoflurane Titration
Electroencephalographic-based monitoring systems such as the bispectral index (BIS) may reduce anaesthetic overdose rates. The investigators hypothesised that goal-directed sevoflurane administration (guided by BIS monitoring)…
- Trial name
- NCT02515019
- Testing
- Bispectral index Monitoring
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Blood Loss
Intraoperative Bleeding During Endoscopic Sinus Surgery
The purpose of this study is to compare the blood loss during sinus surgery looking at two different types of anesthesia: either intravenous anesthesia with propofol or inhalational anesthesia with sevoflurane.
- Trial name
- NCT01014728
- Testing
- propofol, sevoflurane
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Atelectasis, Pulmonary Complications
Low-Flow Anesthesia and Perioperative Atelectasis in Laparoscopic Bariatric Surgery
The goal of this clinical trial is to learn whether low-flow anesthesia reduces perioperative atelectasis compared to normal-flow anesthesia in adults undergoing laparoscopic bariatric surgery.
- Conditions
- Atelectasis, Pulmonary Complications, Ultrasonography, Bariatric Surgery
- Trial name
- NCT07041567
- Testing
- Sevoflurane with normal-flow anesthesia, Sevoflurane with low-flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Low Flow Anesthesia
The Effects of Sevoflurane and Desflurane Used in Low-Flow Anesthesia on Thiol Disulfide Homeostasis
This study aimed to compare the effects of sevoflurane and desflurane used in low-flow anesthesia on thiol-disulfide homeostasis of patients undergoing general anesthesia.
- Trial name
- NCT06810453
- Testing
- A 5 cc venous blood sample was obtained, low-flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- University of Gaziantep