Clinical trials: Sevoflurane, completed
Anesthetic, Sevoflurane
Sevoflurane Concentrations in Children
The sevoflurane concentrations (as well as vital signs, child's date of birth, type of surgery) will be recorded during the first 10 minutes of anesthesia.
- Conditions
- Anesthetic, Sevoflurane, Age
- Trial name
- NCT06510803
- Testing
- The washin of sevoflurane in the GE Ohmeda workstation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- State University of New York at Buffalo
Low-flow Anesthesia
Effects of Minimal and Metabolic Flow Sevoflurane Anesthesia in Gynecological Surgery Patients
The aim of this study is to observe the effects of minimal and metabolically required basal anesthetic gas flow rates delivered by the anesthesia workstation under general anesthesia on body temperature, blood pressure, and heart…
- Trial name
- NCT07465146
- Testing
- Low Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Baskent University
One-Lung Ventilation
Estimating Blood Concentrations of Anaesthetics During One-Lung Ventilation (OLV)
The aims of the study is to determine if end-tidal concentrations of the anaesthetic gases isoflurane and sevoflurane as measured by a standard gas monitor are related to the blood levels during one-lung ventilation.
- Trial name
- NCT02821455
- Testing
- Lung Surgery with One-Lung Ventilation
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Edinburgh
Muscle Relaxation
Effect of Tetanus on Neuromuscular Junction Monitor Performance in Pediatric Patients
The objective of this study is to assess the performance of acceleromyography as a method of evaluation of muscle relaxation after application of tetanus stimulation to obtain stability of responses before administration of…
- Trial name
- NCT02498678
- Testing
- Tetanus
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Rotator Cuff Tear, Shoulder Surgery
Interscalene Brachial Plexus Block and Early Wound-Related Symptoms After Open Rotator Cuff Repair
This exploratory randomized controlled trial evaluated the association of interscalene brachial plexus block (ISB) with early postoperative wound-related symptom scores and perioperative biomarker responses in patients undergoing…
- Conditions
- Rotator Cuff Tear, Shoulder Surgery, Postoperative Recovery
- Trial name
- NCT05499897
- Testing
- Ultrasound-Guided Interscalene Brachial Plexus Block, General Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Yuzuncu Yil University
Postoperative Pain
Pain After Laparoscopic Cholecystectomy
To the investigators' knowledge, no study has looked at differences in postoperative pain when comparing maintenance of anesthesia with isoflurane, desflurane, sevoflurane, and propofol in laparoscopic cholecystectomy.
- Trial name
- NCT00983918
- Testing
- Desflurane, Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Baylor College of Medicine
Oxidative Stress, Sevoflurane Anaesthesia
Effect of Paracetamol Administration Timing on Oxidative Stress in Children Undergoing Sevoflurane Anesthesia
This study investigated the effects of paracetamol administration on oxidative stress in children undergoing inguinal hernia surgery under sevoflurane-based general anesthesia.
- Trial name
- NCT07903259
- Testing
- paracetamol (acetaminophen) solution commercial
- Where
- Serbia
- Volunteers
- 49 people
- Sponsor
- University of Belgrade
Intracranial Pressure, Laparoscopic Surgery
Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery
Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP).
- Conditions
- Intracranial Pressure, Laparoscopic Surgery, Optic Nerve Sheath Diameter
- Trial name
- NCT07525648
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Medipol University
Emergence Delirium
Namsos Anaesthesia Children Outcome Study
Behavioral disturbances are often seen in children after anesthesia both immediately after surgery (emergence delirium) and after discharge from hospital.
- Trial name
- NACOS (NCT04292457)
- Testing
- Propofol, Sevoflurane
- Where
- 2 sites in Norway
- Volunteers
- 761 people
- Sponsor
- Helse Nord-Trøndelag HF
Dreamy State
The Effect of Preoperative Suggestions on Perioperative Dreams and Dream Recalls
Hypothesis: By employing suggestions before the induction of narcosis dreams may be evoked and their content may be directed. The main goal of suggestive techniques in the perioperative phase is to turn the content of dreams…
- Trial name
- dream (NCT01839201)
- Testing
- control, suggestion, dreamfilm
- Where
- Hungary
- Volunteers
- 270 people
- Sponsor
- University of Debrecen
Elderly Patients, Anesthesia
Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients
Emergence of elderly patients from anesthesia may face with cognitive dysfunction or agitation such as delirium. There are reports that using dexmedetomidine as a adjuvant for general anesthesia decreased emergence-agitation in…
- Conditions
- Elderly Patients, Anesthesia, Emergence From Anesthesia, Effects of Dexmedetomidine
- Trial name
- CSUHAPM (NCT01851005)
- Testing
- Dexmedetomidine, Sevoflurane, Propofol and Remifentanil
- Where
- South Korea
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chosun University Hospital
Depression, Anxiety
Effect of General and Non-general Anesthesia on Perioperative Depression or Anxiety
Perioperative depression and/or anxiety play a critical role in patient presentation, satisfaction and outcomes. The aim of this study is to assess the level of perioperative depression and/or anxiety in patients with…
- Trial name
- NCT05315648
- Testing
- anesthesia approach (general anesthesia or non-general anesthesia)
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Radical Mastectomy
Three-level Injection Paravertebral Block vs General Anesthesia in Mastectomy
The purpose of the study is to investigate if paravertebral block for breast surgery may improve postoperative analgesia and shorten length of hospital stay.
- Trial name
- NCT02065947
- Testing
- paravertebral block, fentanyl, propofol, atracurium, lidocaine , adrenaline, ketamine bolus, midazolam
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ramathibodi Hospital
Femur Fracture
Compartment Psoas Block Efficacy and Safety
A randomized controlled trial to assess the efficacy and safety of the prolonged compartment psoas block for analgesia and anesthesia for femur surgery in the elderly
- Trial name
- NCT04648332
- Testing
- Bupivacaine Hydrochloride
- Where
- Ukraine
- Volunteers
- 90 people
- Sponsor
- Bogomolets National Medical University
Brain Tumor, Surgery
Effect of Propofol-Dexmedetomidine on Cerebral Oxygenation and Metabolism During Brain Tumor Resection
Despite theoretical benefits of intravenous agents, volatile agents remain popular. In a study comparing desflurane, isoflurane, and sevoflurane in a porcine model of intracranial hypertension, at equipotent doses and…
- Trial name
- NCT02575521
- Testing
- Propofol-Dexmedetomidine group, Sevoflurane group
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Hernia, Anesthetics Adverse Reaction
Local or Regional or General Anesthesia for Hernia Repair: a Randomized Controlled Trial
This present randomized trial is designed to evaluate the postoperative pain,inflammatory marker, postoperative analgesic medication, length of hospital stay and the modifications of inflammatory mediators in patients undergoing…
- Conditions
- Hernia, Anesthetics Adverse Reaction, Inflammation
- Trial name
- NCT01845376
- Testing
- local anesthesia group, spinal anesthesia group, general anesthesia group
- Where
- Thailand
- Volunteers
- 54 people
- Sponsor
- Mingkwan Wongyingsinn, MD
Postoperative Nausea and Vomiting
Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis
The purpose of this study is to determine how automated recommendations are best presented to optimize the adherence to guidelines on prophylaxis for nausea and vomiting after surgery.
- Trial name
- NCT02625181
- Testing
- Automated recommendation at the start of the case, Automated notification at the start of surgery, Preoperative recommendations: by email
- Where
- United States
- Volunteers
- 27,034 people
- Sponsor
- Vanderbilt University
Pediatric Anesthesia, Emergence Delirium, Anesthesia
Impact of EEG-guided Sevofluorane on Opioid Consumption and Quality of Awakening
This prospective, randomized, single-blind, two-arm parallel-group clinical trial evaluates whether EEG-guided sevoflurane titration affects intraoperative opioid consumption and emergence quality in children undergoing painful…
- Conditions
- Pediatric Anesthesia, Emergence Delirium, Anesthesia, Postoperative Pain, Tonsillectomy
- Trial name
- NCT07714785
- Testing
- EEG-guided, Standard
- Where
- Chile
- Volunteers
- 50 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Valvular Heart Disease, Aortic Disease
Effect of Anesthetics on CD39 and CD73 After Open-heart Surgery
CD39 and CD73 was known protein expressed on surface of Th1 and Th17 cell and modulate immune related reaction. Cardiopulmonary bypass (CPB) can induce inflammatory reaction during cardiac surgery, and induce immunosuppression.
- Trial name
- NCT02136979
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 2 people
- Sponsor
- Konkuk University Medical Center
Stroke, Cerebrovascular Stroke
General Anesthesia for Endovascular Thrombectomy; A Pilot Study.
This study evaluates the outcomes of stroke patients treated for intravascular thrombectomy, using either a local anesthetic with sedation, or a general anesthetic.
- Conditions
- Stroke, Cerebrovascular Stroke, Brain Ischemia, Brain Diseases
- Trial name
- NCT02639806
- Testing
- Sevoflurane, Lidocaine
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of Saskatchewan