Clinical trials: Sevoflurane, completed
COVID-19, Respiratory Failure
Comparative Study of Anaconda System Use Versus Conventional Sedation in COVID-19 Patients.
At the beginning of 2020, a global alert emerged which saturated intensive care units due to COVID-19 worldwide. This caused a need for mechanical ventilation due to atypical pneumonias that had a rapid evolution and respiratory…
- Trial name
- NCT06208592
- Testing
- Sevoflurane with AnaConDa
- Where
- Mexico
- Volunteers
- 43 people
- Sponsor
- Hospital Español de Mexico
Anesthesia
Feasibility and Safety Properties of Metabolic Flow Anesthesia Driven by Automated Gas Control in Pediatric Patients
Low flow anesthesia was considered to be causing rebreathing, hypoxia and hypercarbia in the past. However, developing technologies made anesthesia ventilators safer.
- Trial name
- NCT05644340
- Testing
- Speed 8 (Fast balancing gas flow), Speed 4 (Medium speed balancing gas flow)
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Istanbul University
Delayed Graft Function, Renal Outcome After Kidney Transplantation
Volatile Anesthetic Protection Of Renal Transplants 2
To compare the effect of a sevoflurane based anesthesia versus a propofol based anesthesia on the incidence of DGF in recipients of kidneys of donation after circulatory death (DCD) and donation after brain death (DBD) donors
- Conditions
- Delayed Graft Function, Renal Outcome After Kidney Transplantation, Acute Rejection (AR) of Transplanted Kidney, Graft Survival
- Trial name
- VAPOR-2 (NCT02727296)
- Testing
- sevoflurane, propofol
- Where
- 5 sites in Denmark, Netherlands and 2 more
- Volunteers
- 488 people
- Sponsor
- University Medical Center Groningen
Emergence Agitation
Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation
The goal of this clinical trial is to compare Propofol versus Dexmedetomidine in children undergoing squint surgery. The main question it aims to answer is: Which drug is more effective in preventing the appearance of Emergence…
- Trial name
- NCT06312618
- Testing
- Propofol, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Opioid-Related Disorders, Substance-Related Disorders
Effects of Combined Sevoflurane and Nitrous Oxide Inhalation - 14
The purpose of this study is to determine the effects of combined sevoflurane and nitrous oxide inhalation on mood, psychomotor performance, and the pain response in humans.
- Trial name
- NCT00000262
- Testing
- 30% Nitrous oxide, 0.4% Sevoflurane, 0.2% sevoflurane
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Chicago
Adverse Event
Comparison of the Sedation Effect of Esketamine and Sevoflurane for Pediatric Ophthalmological Procedure
Emergence agitation is the most common reason for post-anesthesia care unit delay. Sevoflurane is used frequently inhalational anaesthetic agent to provide pediatric anaesthesia because of the nonirritant nature.
- Trial name
- NCT05321160
- Testing
- Esketamine, Sevoflurane
- Where
- China
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Emergence Delirium (Derlenme Deliryumu)
Brain Monitors to Reduce Child Confusion After Anesthesia
The goal of this clinical trial was to learn if using a brain monitor to adjust anesthesia (sleep medicine) during surgery could prevent emergence delirium (severe confusion and agitation upon waking) in children aged 2 to 12…
- Trial name
- NCT07826559
- Testing
- BIS-Guided Anesthesia, Standard Care Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Baskent University
Urinary Surgery, General Anesthesia
Different Anesthesia Maintain Protocol Effect the Outcome of the Patients
This prospective open-label randomized study, patients were having elective urological surgery scheduled to last longer than 1 h under necessitating general anesthesia.Group-P: (Propofol group): 3 mg kg-1 min-1 propofol was…
- Trial name
- NCT04443946
- Testing
- Propofol, 1% Sevoflurane, 1% Sevoflurane continue
- Where
- China
- Volunteers
- 50 people
- Sponsor
- China International Neuroscience Institution
AKI - Acute Kidney Injury
Sevoflurane and Dexmedetomidine's Contrasting Renal Impacts After Non-Cardiac Surgery
Postoperative acute kidney injury (PO-AKI) is a significant complication, especially after complex surgeries. The choice of anesthetic may influence PO-AKI risk.
- Trial name
- NCT06835010
- Testing
- Dexmedetomidine, Sevoflurane inhalant product
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Other Specified Injuries of Vocal Cord, Sequela
Laryngeal Injuries After Anesthesia Induction With Three Different Sevoflurane Concentrations (Without Muscle Relaxant)
Anesthesia induction and tracheal intubation can be performed with and without neuromuscular blocking agents (NMBAs). Tracheal intubation can be performed with sevoflurane instead of NMBAs; intubating conditions are similar and…
- Trial name
- SEVODosage (NCT01896245)
- Testing
- sevoflurane 1,0, sevoflurane 1,2, sevoflurane 1,4
- Where
- Germany
- Volunteers
- 90 people
- Sponsor
- University of Rostock
Inflammatory Lung Injury, Ischemia-Reperfusion Lung Injury
Anesthetics to Prevent Lung Injury in Cardiac Surgery
The purpose of this study is to investigate whether the use of inhaled anesthetics, compared to intravenous anesthetics, can affect the amount of lung inflammation and postoperative respiratory complications seen after cardiac…
- Conditions
- Inflammatory Lung Injury, Ischemia-Reperfusion Lung Injury, Postoperative Pulmonary Complications
- Trial name
- APLICS (NCT02918877)
- Testing
- Sevoflurane, Propofol
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Beth Israel Deaconess Medical Center
Acute Respiratory Distress Syndrome
SEvoflurane for Sedation in ARds
This study evaluates whether a sedation with inhaled sevoflurane will decrease mortality and increase time off the ventilator at 28 days in patients with acute respiratory distress syndrome (ARDS).
- Trial name
- SESAR (NCT04235608)
- Testing
- Inhaled sedation with sevoflurane, intravenous sedation with propofol
- Where
- 33 sites in France
- Volunteers
- 700 people
- Sponsor
- University Hospital, Clermont-Ferrand
Hemodynamic Stability, Pulmonary Diseases or Conditions
A Study Comparing Sevoflurane and Propofol in Patients Undergoing Endobronchial Ultrasound Guided Needle Aspiration
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive procedure used to obtain samples from mediastinal and hilar lymph nodes or lung parenchymal lesions for diagnostic and staging…
- Conditions
- Hemodynamic Stability, Pulmonary Diseases or Conditions, Complication of Anesthesia
- Trial name
- NCT07338578
- Testing
- propofol, Sevoflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi
Postoperative Cognitive Dysfunction
Optic Nerve Sheath Diameter and Postoperative Cognitive Disfunction at Laparoscopic Surgery
Purpose: Pneumoperitoneum during laparoscopic abdominal surgery increases intra-abdominal pressure (IAP), potentially altering intracranial pressure (ICP) and cerebral oxygenation, with unclear implications for early…
- Trial name
- NCT07264764
- Testing
- Optic nerve sheath diameter (ONSD)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Duzce University
Anesthesia Intubation Complication
Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane Induction
The purpose of this study is to determine the amount of propofol required to achieve 50% of patients obtaining a perfect ("excellent") intubation score of 5 on the Steyn modification of the Helbo-Hansen Intubation Score, when…
- Trial name
- NCT01150838
- Testing
- propofol
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Virginia
Low Flow Anesthesia
The Effects of Sevoflurane and Desflurane Used in Low-Flow Anesthesia on Thiol Disulfide Homeostasis
This study aimed to compare the effects of sevoflurane and desflurane used in low-flow anesthesia on thiol-disulfide homeostasis of patients undergoing general anesthesia.
- Trial name
- NCT06810453
- Testing
- A 5 cc venous blood sample was obtained, low-flow anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- University of Gaziantep
Postoperative Pain
Effect of Total Intravenous Anaesthesia With Propofol on Postoperative Pain After Bilateral Third Molar Surgery
Propofol is one of the most commonly used intravenous anaesthetic drugs both for induction and maintenance of general anaesthesia.
- Trial name
- NCT03058341
- Testing
- propofol, Sevoflurane
- Where
- Hong Kong
- Volunteers
- 96 people
- Sponsor
- The University of Hong Kong
Hypothermia
A Comparison of Inhalation vs. Intravenous Induction
To compart differences on the effect on core temperature between anesthetic induction with intravenous propofol versus inhalation induction with sevoflurane
- Trial name
- INHvsIV (NCT02331108)
- Testing
- Selection of anesthetic induction technique
- Where
- United States
- Volunteers
- 331 people, healthy volunteers welcome
- Sponsor
- Albert Einstein Healthcare Network
Deep Inferior Epigastric Artery Perforator Flap Breast Reconstruction
The Effect of Volatile Anesthesia and Total Intravenous Anesthesia on Shedding of the Endothelial Glycocalyx in Patients Undergoing Mastectomy and Breast Reconstruction Using Deep Inferior Epigastric Artery Perforator Free Flap
The aim of this study was to investigate the effects of total intravenous and inhalation anesthesia on the damage of endothelial glucocorticoids by comparing the concentration of syndecan-1 in patients undergoing mastectomy and…
- Trial name
- NCT05136508
- Testing
- Propofol, Sevoflurane
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Yonsei University
One-Lung Ventilation, Thoracic Surgery, Video-Assisted
Effect of Sevoflurane and Remimazolam on Arterial Oxygenation During One-lung Ventilation
The goal of this clinical trial is to compare the effect of sevoflurane and remimazolam on arterial oxygenation during one lung ventilation in patients undergoing video-assisted thoracoscopic surgery.
- Conditions
- One-Lung Ventilation, Thoracic Surgery, Video-Assisted, Remimazolam
- Trial name
- NCT05907525
- Testing
- Remimazolam, 1% propofol
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Pusan National University Yangsan Hospital