Clinical trials: Sevoflurane, completed
Emergence Agitation, Anesthetics
The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty
Emergence agitation, defined as restlessness, disorientation, arousal, and/or inconsolable crying, is a common phenomenon seen in the early phase of recovery from general anesthesia; this may cause respiratory depression, nausea…
- Conditions
- Emergence Agitation, Anesthetics, Rhinoplasty
- Trial name
- NCT05601674
- Testing
- : Conventional flow Anesthesia, Low Flow Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Inonu University
Children, Hernia, Inguinal
Comparing Inhalation and Total Intravenous Anesthesia Methods
This study compares the effects of anesthesia using target-controlled infusion (TCI) and inhalation methods on pediatric patients undergoing inguinal hernia repair.
- Trial name
- TIVA-IHA (NCT06467279)
- Testing
- Target Controlled İnfusion, Inhalation anesthetic
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- TC Erciyes University
Propofol, Fentanyl
Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring
The objective of this study is to evaluate the effect of adding dexmedetomidine on evoked potentials in adult patients undergoing spinal surgery under intravenous anesthesia
- Conditions
- Propofol, Fentanyl, Dexmedetomidine, Sevoflurane
- Trial name
- NCT06210061
- Testing
- Propofol-Fentanyl, Propofol-Fentanyl-Dexmedetomidine, Propofol-Fentanyl-Sevoflurane
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams University
Hormones, Anesthesia, Conduction
The Impact of Regional Anaesthesia on Hormone Levels in Thoracic Surgery.
Basic aspects of thoracic anaesthesia are general anesthesia often combined with regional anesthesia, intubation with double lumen tube and separation of lung ventilation.
- Conditions
- Hormones, Anesthesia, Conduction, Thoracic Surgical Procedure
- Trial name
- NCT04414488
- Testing
- Thoracic paravertebral block (ThPVB)
- Where
- Poland
- Volunteers
- 119 people
- Sponsor
- Medical University of Silesia
Asa I-III Patients, Intubated Patients
Dental Injury Related To Conventional Direct Laryngoscopy
This research explores the occurrence of minor dental injuries and their associated effects by employing the transillumination technique with a cold light source.
- Conditions
- Asa I-III Patients, Intubated Patients, Laryngoscopy
- Trial name
- dentalinjury (NCT06760247)
- Testing
- intubated general anesthesia with propofol IV, rocuronium IV ,sevoflurane and N2O gas
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Selcuk University
Anesthesia
Improving Information Extraction From EEG on Cerebral Anesthetic Drug Effects
This is an interventional, randomized controlled study in health volunteers that involves collecting data on raw EEG waves measuring various combinations of anesthetic drugs during standardized drug titration.
- Trial name
- NCT02043938
- Testing
- SedLine EEG sensor
- Where
- Netherlands
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Masimo Corporation
Obesity, Anesthesia
Optimal Anesthesia for Morbidly Obese Patients
Obese patients have a higher risk of anesthesia compared to the non-obese, including difficult intubation, rapid desaturation, difficult vascular access, and delayed recovery from anesthesia.
- Trial name
- NCT04395248
- Testing
- Exploring potential risk factors of difficult intubation using ultrasound, Radial artery catheterization using ultrasound guidance or blind palpation, Comparing the effectiveness of preoxygenation between high-flow nasal cannula and facemask
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
General Anesthesia, Intraoperative Monitoring
Equivalent MAC in General Anesthesia
This observational study aims to evaluate the clinical applicability of the Equivalent Minimum Alveolar Concentration (eMAC) parameter during general anesthesia.
- Conditions
- General Anesthesia, Intraoperative Monitoring, Anesthetic Depth
- Trial name
- NCT07197567
- Testing
- Sevoflurane + Remifentanil, Sevoflurane + Propofol + Remifentanil
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sakarya University
Free Tissue Flaps
Effect of Epidural Anesthesia on Blood Flow in Arterial Anastomosis of Free Flap
Comparing the changes of arterial anastomotic blood flow between general anesthesia alone and general anesthesia with epidural anesthesia in patients who undergoing free flap transposition using Duplex ultrasound.
- Trial name
- NCT03330808
- Testing
- Epidural anesthesia
- Where
- South Korea
- Volunteers
- 52 people
- Sponsor
- Asan Medical Center
Dexmedetomidine Infusion, Pediatric
Comparison of Caudal Block Versus Dexmedetomidine Infusion in Pediatric Patients Undergoing Hypospadias Repair Surgery
Pain is one of the most misunderstood, underdiagnosed, and untreated medical problems, particularly in children. New Joint Commission on Accreditation of Health Care Organization regards pain as fifth vital sign and requires…
- Conditions
- Dexmedetomidine Infusion, Pediatric, Hypospadias Repair Surgery
- Trial name
- NCT04331418
- Testing
- Dexmedetomidine, caudal block
- Where
- Egypt
- Volunteers
- 135 people
- Sponsor
- Tanta University
Propofol, Sevoflurane
Sevoflurane Versus Propofol in Endovascular Coiling of Cerebral Aneurysm
The goal of this observational study is to learn about the anti-inflammatory effects of anesthetics on patients undergoing endovascular coiling of cerebral aneurysm.
- Trial name
- NCT06666959
- Testing
- Anesthesia Agent
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Tongji Hospital
Heart Diseases
Inhaled Anesthetics and Myocardial Strain
Speckle tracking imaging measuring software will be used for offline analysis of transesophageal echocardiogram (TEE) -acquired images of the left ventricle(LV) in four chambers(4C), two chambers (2C) and long axis (LAX) views to…
- Trial name
- NCT03569085
- Testing
- Sevoflurane, Isoflurane
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Kathirvel Subramaniam
Children, Urologic Diseases
Emergence Agitation Between Sevoflurane and Desflurane in Pediatric
Sevoflurane is the volatile anesthetic agent of choice in pediatric surgery. Nevertheless, sevoflurane anesthesia had the high incidence of emergence delirium compared to halothane and isoflurane.Bortone L et al.reported…
- Conditions
- Children, Urologic Diseases, Ambulation Difficulty
- Trial name
- NCT01235143
- Testing
- Desflurane, Sevoflurane
- Where
- Thailand
- Volunteers
- 136 people
- Sponsor
- Prince of Songkla University
Coronary Artery Disease, Delirium
The PATHFINDER Study: A Feasibility Trial
The main purpose of this study is to determine whether a rational strategy of EEG guided multimodal general anesthesia using target specific sedative and analgesics could result in enhanced recovery after anesthesia and surgery…
- Trial name
- PATHFINDER (NCT04016740)
- Testing
- Ropivacaine, Ketamine, Remifentanil
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Beth Israel Deaconess Medical Center
Anesthesia
Comparing EEG Patterns in Different Age Groups During General Anesthesia With Sevoflurane
This study is being conducted to evaluate and assess the electroencephalography wave patterns in different age patients undergoing surgery under general anesthesia.
- Trial name
- NCT03559504
- Testing
- Sevoflurane Inhal Soln
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Inhalation Anesthesia, Lung Injury
The Effect of Sevoflurane and Desflurane on Clara Cell Protein on the Lung
Inhalation anesthesia; It means that the anesthetic drugs taken by the respiratory tract pass into the blood through the lung alveoli, reach the brain tissue, and create an anesthetic effect according to the density in the brain…
- Trial name
- NCT04645316
- Testing
- Sevoflurane, Desflurane, Propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Inonu University
Anesthesia
EEG Profiles During General Anesthesia : a Comparative Study Between Sevoflurane and Propofol
A cerebral pharmacodynamic feedback may help the anesthesiologist to adjust anesthetics administration. The BIS, which provides a single number resulting from an algorithm calculated from cortical EEG parameters, may play this…
- Trial name
- NCT02893904
- Testing
- EEG monitoring, Target Controlled Infusion
- Where
- France
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Hôpital Armand Trousseau
Blood Pressure, Hypotension Drug-Induced
Comparison Between Inhalation and Intravenous Induction of Anaesthesia During Interventional Mitral Valve Repair
The induction of anaesthesia is one of the most critical situations for high-risk-patients undergoing interventions surgery. For several reasons, it is crucial to maintain adequate blood pressure and cardiac output during this…
- Trial name
- COMPETENT (NCT04865614)
- Testing
- Etomidate, Sevoflurane
- Where
- Germany
- Volunteers
- 57 people
- Sponsor
- Heidelberg University
Breast Cancer
Evaluation of Impact of Nitrous Oxide on PONV in Breast Surgeries
Postoperative nausea and vomiting (PONV) is considered one of the most unpleasant postoperative discomforts and lead to serious complications of aspiration of gastric contents, suture dehiscence, esophageal rupture, subcutaneous…
- Trial name
- NCT02736604
- Testing
- nitrous oxide anesthesia, air anesthesia, laryngeal mask airway (LMA Supreme Size 3/4
- Where
- India
- Volunteers
- 250 people
- Sponsor
- Tata Memorial Hospital