Clinical trials: Sevoflurane
Entropion
The Effect of Preoperative Ketamine on the Emergence Characteristics in Children Undergoing Entropion Surgery
The investigators evaluate extubation time and recovery profiles in children undergoing entropion surgery.
- Trial name
- NCT02916407
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Inje University
Anesthesia, General
Estimate the Behavior of Chinese Anesthesiologists Practicing General Anesthesia With Sevoflurane
This registry is primarily aiming to demonstrate the correlation between good practices of anesthesiologists and patient related outcomes including decreased overall anesthesia cost.
- Trial name
- NCT01199471
- Where
- 40 sites in China
- Volunteers
- 4,000 people
- Sponsor
- Abbott
Emergence Agitation
Comparison of Emergence Agitation Between Sevoflurane and Desflurane Anesthesia After Orthognathic Surgery
Emergence agitation is a major concern in patients undergoing orthognathic surgery. The patients may experience the sense of suffocation during emergence due to nasotracheal intubation and orofacial edema.
- Trial name
- NCT01878656
- Testing
- Sevoflurane, Desflurane
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Chung-Ang University Hospital
Stroke
SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke
Objectives: This study aims to estimate overall treatment benefit (improvement in disability) among acute ischemic stroke patients that are randomized to General Anesthesia (GA) compared with Sedation (CS) during endovascular…
- Trial name
- SEGA (NCT03263117)
- Testing
- Sedation, General Anesthesia (GA), Intra-arterial Thrombectomy
- Where
- 11 sites in United States
- Volunteers
- 260 people
- Sponsor
- The University of Texas Health Science Center, Houston
Inguinal Hernia
A Multi-site Randomized Controlled Trial Comparing Regional and General Anesthesia for Effects on Neurodevelopmental Outcome and Apnea in Infants
The primary purpose of the GAS study is to determine whether different types of anesthesia (Regional versus General) given to 720 infants undergoing inguinal hernia repair results in equivalent neurodevelopmental outcomes.
- Trial name
- GAS (NCT00756600)
- Testing
- Regional Anesthesia, General Anesthesia
- Where
- 30 sites in United States, Australia and 5 more
- Volunteers
- 643 people
- Sponsor
- Boston Children's Hospital
Laparoscopic Gastric Bypass Surgery, Ketamine
Perioperative Ketamine for Pain With Gastric Bypass
Opioid medications such as morphine, hydrocodone and oxycodone are standard for treating pain after surgery, however there are disadvantages.
- Trial name
- NCT03448068
- Testing
- Ketamine, Standard therapy
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Hip Fractures, Anesthesia
Does Optimized General Anesthesia Care Reduce Postoperative Delirium?
Postoperative delirium occurs in up to 65% of elders undergoing surgery for repair of a hip fracture and this complication is independently associated with increased morbidity, mortality, length of hospital stay, and placement in…
- Conditions
- Hip Fractures, Anesthesia, Delirium
- Trial name
- OPCare (NCT02604459)
- Testing
- cerebral oximeter (Fore-Sight), depth of anesthesia monitor (BIS), BP management
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- University of Missouri-Columbia
Anesthesia
Evaluation of Bispectral Index (BIS™) and Levels of Sedation With Common Inhalational Anesthetics in Healthy Volunteers (OLIVER)
To investigate the relationship between BIS™ and inhaled anesthetics across a wide range of anesthetic concentration and hypnotic states, and to provide evidence to support BIS™ performance in use with Isoflurane, Sevoflurane and…
- Trial name
- OLIVER (NCT04602546)
- Testing
- BIS Complete Monitoring System
- Where
- 3 sites in United States
- Volunteers
- 211 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Cystoscopes, Baxter Anaesthesia Brand of Desflurane
Comparing Desflurane to Sevoflurane for the Effect on Recovery Time in Patients Undergoing Urological Cystoscope Surgery
This is a single-center, prospective, randomized, double-blind, double-arm trial including 68 subjects scheduled to undergo urological cystoscope surgeries under general anesthesia (GA) with intubation through a laryngeal mask…
- Conditions
- Cystoscopes, Baxter Anaesthesia Brand of Desflurane, Sevoflurane
- Trial name
- NCT01219881
- Testing
- Desflurane, Sevoflurane
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Anesthesia, General
Sugammadex After Continuous Infusion of Rocuronium During Sevoflurane and Propofol Anesthesia (P05949; MK-8616-028)
The objective of the trial was to show equivalence in recovery from neuromuscular block after a single dose of 4.0 mg/kg sugammadex, administered at first twitch (T1) 3-10% after continuous infusion of rocuronium, between…
- Trial name
- NCT00559468
- Testing
- Sugammadex, Rocuronium, Sevoflurane
- Volunteers
- 52 people
- Sponsor
- Merck Sharp & Dohme LLC
Post-operative Nausea and Vomiting
Prevention of Post-Operative Nausea and Vomiting With Propofol Infusion
The purpose of this study is to clarify whether or not a low-dose propofol infusion can effectively prevent postoperative nausea and vomiting (PONV) in patients who have a documented history of PONV and/or motion sickness.
- Trial name
- PONV (NCT05759481)
- Testing
- Hybrid anesthesia (propofol + sevoflurane), Propofol only TIVA
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Milton S. Hershey Medical Center
Elevated Cardiac Risk, Coronary Arteries Disease Risk
Cardiovascular Safety of Xenon in General Anaesthesia, in Patient With Cardiovascular Risk in Non Cardiac Surgery
The Primary Objective is to show non inferiority in cardiac safety (i.e myocardial necrosis-MN- assessed by positive cardiac Troponin I -cTnI- ultrasensitive assay) of a Xenon based general anesthesia procedure in patients with…
- Trial name
- CARVASAXe (NCT01120405)
- Testing
- Xenon, Sevoflurane
- Where
- 13 sites in France
- Volunteers
- 600 people
- Sponsor
- Air Liquide Santé International
Cerebral Hypoxia, Postoperative Cognitive Dysfunction
The Difference in Cerebral Oxygenation Between Propofol and Sevoflurane
the purpose of this study is to investigate whether propofol and sevoflurane have difference effect on cerebral oxygenation .
- Trial name
- NCT01757561
- Testing
- propofol, sevoflurane
- Where
- China
- Volunteers
- 144 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Postoperative Pain, Preoperative Anxiety
Relationship Between Preoperative Anxiety, Postoperative Pain, and Emergence Delirium in Pediatric Surgery
The goal of this observational study is to learn if preoperative anxiety levels can predict the quality of early postoperative recovery, pain intensity, and the occurrence of emergence delirium in pediatric patients aged 2 to 7…
- Conditions
- Postoperative Pain, Preoperative Anxiety, Emergence Delirium in Pediatric Anesthesia, Urogenital Diseases
- Trial name
- NCT07343388
- Testing
- Standardized Perioperative Management and Observational Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Aydin Adnan Menderes University
Anesthesia
Physiological Effects of Nitrous Oxide on Anaesthesia
Nitrous oxide is the oldest anaesthetic agent still in routine use today. Despite huge changes in the pharmacology of volatile anaesthetic agents and intravenous anaesthetics, the unique properties of nitrous oxide have…
- Trial name
- NCT01092923
- Testing
- sevoflurane on air/O2, sevoflurane in N2O/O2
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Austin Health
Eosinophilic Esophagitis
Comparing Anesthetic Techniques in Children Having Esophagogastroduodenoscopies
The purpose of this research study is to compare the safety and effectiveness of three commonly used techniques for delivering anesthesia during a procedure known as esophagogastroduodenoscopy.
- Trial name
- NCT02038894
- Testing
- Intubated with Sevoflurane (IS), Intubated with Propofol (IP), Zofran - no intubation
- Where
- United States
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Acute Pain
ANI Versus Standard Care in Surgical Patients Receiving Balanced Sevoflurane-Fentanyl Anesthesia
This study aims to be a randomized, controlled study of ANI-guided opioid administration versus standard clinical practice in surgical patients undergoing general anesthesia with balanced sevoflurane-fentanyl.
- Trial name
- NCT03684590
- Testing
- ANI-guided opioid administration, Standard opioid administration
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Intubation; Difficult
Nasotracheal Intubation Using Shikani Optical Stylet
Difficult airways is still a challenging issue for the anesthesiologists in spite of the development of various techniques.Shikani optical stylet(SOS), combining the features of fiberoptic bronchoscope and a lightwand, has been…
- Trial name
- SOS (NCT00963677)
- Testing
- Nasotracheal Intubation through seeing optical stylet (SOS)
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Central South University
Minimal Flow Anesthesia, General Anaesthesia
Minimal Flow Anesthesia and Infection Risk
This study is being done to find out if the heat and moisture that build up during minimal flow anesthesia can lead to the growth of germs (microorganisms) inside the anesthesia equipment.
- Conditions
- Minimal Flow Anesthesia, General Anaesthesia, Inhalation Anesthesia, Infection Risk
- Trial name
- NCT07092046
- Testing
- Sevoflurane (Volatile Anesthetic), Propofol 1%, Remifentanil 2 MG
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Emergence Agitation
The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children
The purpose of this study is to determine whether depth of anesthesia has an effect on emergence agitation (EA) in children age 2 - 8 years old.
- Trial name
- NCT00990769
- Testing
- Depth of anesthesia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University