Clinical trials: Sildenafil
Androgenic Alopecia
Comparison Between Efficacy of Topical Sildenafil 2% and Topical Minoxidil 5% in Treatment of Androgenic Alopecia
Androgenetic alopecia (AGA) is hair loss with specific clinical pattern, It Is characterized by follicular miniaturization, which occurs due to systemic androgens and genetic factors.
- Trial name
- NCT05369481
- Testing
- Sildenafil 2%, Minoxidil 5 %
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Mohammed Abd El Mawgoud Amer
Labor Preterm Requiring Hospitalization
Management of Acute Preterm Labor: Nifedipen Alone or Combined With Cildenafil Citrate
The aim of this study is to assess whether or not the emergency tocolytic effect of combined nifedipine and sildenafil citrate will have a superior effect over nifedipine alone in terms of inhibiting eminent preterm labor and…
- Trial name
- NCT02337881
- Testing
- nifedipen, Sildenafil
- Where
- 2 sites in Egypt, Saudi Arabia
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Al Hayat National Hospital
Subfertility, Female
Effect of Sildenafil Citrate Compared to Estrogen as Adjuvant Therapy for Unexplained Infertility
. This study aimed to determine and compare the effect of vaginal sildenafil citrate and estradiol valerate on endometrial thickness, blood flow and pregnancy rates in infertile women.
- Trial name
- NCT05753098
- Testing
- estrogen therapy, Sildenafil, Clomiphene Citrate 50mg
- Where
- Egypt
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Erectile Dysfunction
Psychotherapy and Pharmacotherapy in the Treatment of Erectile Dysfunction: A Pilot Study
The study involved the administration of pharmacotherapy and cognitive behavior psychotherapy to individuals suffering from erectile dysfunction. The study was randomized controlled trial with two arms involving a control group.
- Trial name
- NCT04179747
- Testing
- Cognitive Behavioral Psychotherapy, Sildenafil Citrate 50Mg Tab
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- International Islamic University, Islamabad
Pulmonary Hypertension, Hemodialysis Complication
Sildenafil in Hemodialysis Patients With Pulmonary Hypertension
Sildenafil is a phosphodiesterase inhibitor that can exert a nitric oxide-mediated vasodilation effect, so it's considered one of the preferred agents especially in hypoxia induced pulmonary hypertension, can achieve pulmonary…
- Trial name
- NCT03763045
- Testing
- Sildenafil
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Liver Fibrosis
Sildenafil for Liver Fibrosis in Adolescents and Adults After Fontan Operation
Fontan operation is currently the most common procedure performed in patients with single-ventricle physiology. This surgery allows for passive caval blood flow to the pulmonary arteries in the absence of a subpulmonary pump and…
- Trial name
- NCT04908657
- Testing
- Sildenafil 20 MG
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Persistent Pulmonary Hypertension
Efficacy and Safety of Milrinone Versus Sildenafil in the Treatment of Neonates With Persistent Pulmonary Hypertension
Compare the effect of milrinone versus sildenafil in treatment of neonates with persistent pulmonary hypertension.
- Trial name
- ESMPPHTN (NCT04391478)
- Testing
- Milrinone, Sildenafil
- Volunteers
- 40 people
- Sponsor
- Rania Ali El-Farrash
Pulmonary Hypertension, Systolic Dysfunction
Safety and Efficacy Study of HGP1207 in Patients With Pulmonary Hypertension
The purpose of this study is to investigate the safety and clinical efficacy of HGP1207 (Sildenafil) in subjects with pulmonary hypertension associated with systolic heart failure.
- Trial name
- NCT01913847
- Testing
- Sildenafil
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Polycystic Ovarian Syndrome (PCOS), Polyendocrine Metabolic Ovarian Syndrome (PMOS)
Comparison of Clomiphene Alone Versus Clomiphene Plus Sildenafil for Ovulation in Women With Polycystic Ovary Syndrome
The goal of this randomized clinical trial is to compare the effectiveness of clomiphene citrate alone with clomiphene citrate combined with sildenafil citrate for inducing ovulation and achieving pregnancy in women with…
- Trial name
- NCT07769476
- Testing
- Clomiphene Citrate 100 mg, Sildenafil Citrate 25Mg Tab
- Where
- Pakistan
- Volunteers
- 98 people
- Sponsor
- Nishtar Medical University
Pulmonary Hypertension
Pharmacokinetics and Pharmacdynamics of Sildenafil
The study is being done to investigate what happens to sildenafil in the body and how long it takes to get rid of this drug. Understanding how long the drug stays in the body and how it is changed by the body will help doctors…
- Trial name
- NCT00718185
- Testing
- Obtain blood specimens
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Children's Hospital of Philadelphia
Hypogonadism, Erectile Dysfunction
Testosterone for Penile Rehabilitation After Radical Prostatectomy
The purpose of this study is to determine the effectiveness of testosterone replacement therapy (TRT) in men following surgery to remove the prostate in improving erectile function.
- Trial name
- NCT00848497
- Testing
- Testim®, Viagra®
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Mohit Khera
Pulmonary Fibrosis, Hypertension, Pulmonary
Sildenafil to Increase Exercise Capacity in Individuals With Idiopathic Pulmonary Fibrosis and Pulmonary Hypertension
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease that affects an individual's ability to breathe. Currently, no medications can reverse the damage to the lungs caused by IPF, but individuals are encouraged to engage…
- Trial name
- NCT00352482
- Testing
- Sildenafil (50 mg)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cystic Fibrosis
Safety and Efficacy of Sildenafil in Cystic Fibrosis (CF) Lung Disease
The purpose of this study is to determine whether sildenafil can decrease inflammation in CF lung disease.
- Trial name
- NCT00659529
- Testing
- sildenafil
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Jewish Health
Solid Tumor
Study of Regorafenib and Sildenafil for Advanced Solid Tumors
This is a phase 1 study of sildenafil in combination with regorafenib in patients with progressive advanced solid tumors. A modified 3+3 dose escalation design will be conducted for the dose escalation of the treatment…
- Trial name
- NCT02466802
- Testing
- Regorafenib, Sildenafil Citrate
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Virginia Commonwealth University
Single Ventricle Heart Disease After Fontan Surgery
Study of Effects of Sildenafil on Patients With Fontan Heart Circulation
The study will investigate the cardiovascular effects of sildenafil on patients with Fontan circulation. Recent studies suggest that sildenafil may improve exercise in patients with Fontan circulation.
- Trial name
- NCT01815502
- Testing
- Cardiac catheterization
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Bladder Cancer
Role of Low-intensity Shock Wave Therapy in Penile Rehabilitation Post Nerve Sparing Radical Cysto-prostatectomy
The aim of this clinical trial is to evaluate the role of extracorporeal low-intensity shock wave therapy in penile rehabilitation post nerve sparing radical cysto-prostatectomy.
- Trial name
- NCT02422277
- Testing
- LI-ESWT group, PDE-5 inhibitors group
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Persistent Pulmonary Hypertension of Newborn
Nitro Oxide Inhalation Continued With Sildenafil on Neonatal Persistent Pulmonary Hypertension
Nitro Oxide (NO) inhalation was recognized as an effect treatment of Neonatal Persistent Pulmonary Hypertension (PPHN), while the safety of NO long term application was under investigation.
- Trial name
- NCT01373749
- Testing
- NO inhalation, NO inhalation continued with sildenafil
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Third Military Medical University
Recurrent Pregnancy Loss
Effect of Sildenafil Citrate on Mid Luteal Phase Uterine Artery Blood Flow in Patients With Recurrent Pregnancy Loss
Patients with recurrent pregnancy loss are known to have decreased uterine artery blood flow. Nitric oxide plays a major role in increasing uterine blood flow during the luteal phase.
- Trial name
- NCT04718233
- Testing
- Sildenafil 25Mg Tablet
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pulmonary Hypertension
To Provide Sildenafil Therapy To Eligible Adult Patients With Pulmonary Arterial Hypertension For 112 Weeks
The purpose of this study is to provide sildenafil therapy to eligible adult patients with pulmonary arterial hypertension (PAH) and to the patients who completed the A1481142 study for the treatment of PAH in Poland.
- Trial name
- NCT00946114
- Testing
- sildenafil
- Where
- 2 sites in Poland
- Volunteers
- 32 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Systemic Sclerosis, Ulcer
Prevention and Treatment of Digital Ulcers in Systemic Sclerosis
Systemic sclerosis is an orphan, multiorgan disease affecting the connective tissue of the skin and several internal organs. Digital ulcers are frequent and have a major impact on the quality of life in patients with systemic…
- Trial name
- NCT01836263
- Where
- 11 sites in France, Germany and 4 more
- Volunteers
- 420 people
- Sponsor
- marco matucci cerinic