Clinical trials: Sildenafil, completed
Impotence
A Randomized Double Blind, Placebo Controlled Balanced 4-Way Crossover Study To Assess The Efficacy Of Single Oral Doses
The primary aim of this study is to assess how effective PF-00592379 is in restoring penile erections in patients with erectile dysfunction.
- Trial name
- NCT00273416
- Testing
- PF-00592379, Sildenafil 100mg
- Where
- 2 sites in Norway, United Kingdom
- Volunteers
- 32 people
- Sponsor
- Pfizer
Pulmonary Hypertension
Evaluation of the Pharmacodynamic Effect of the Combination of Sildenafil and Riociguat on Blood Pressure and Other Safety Parameters.
Pulmonary Arterial Hypertension (PAH) is a severe progressive disease with a high mortality. Although several drugs are available for the treatment of PAH none offer a cure, therefore there is still a high medical need for new…
- Trial name
- PATENT PLUS (NCT01179334)
- Testing
- Riociguat (Adempas, BAY63-2521), Sildenafil
- Where
- 25 sites in United States, Austria and 7 more
- Volunteers
- 18 people
- Sponsor
- Bayer
Waldenstrom's Macroglobulinemia
Sildenafil Citrate in Waldenstrom's Macroglobulinemia
The purpose of this study is to determine the effects (good or bad) that sildenafil (Viagra) has on patients with slow growing Waldenstrom's macroglobulinemia (WM).
- Trial name
- NCT00165295
- Testing
- Sildenafil citrate (Viagra)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dana-Farber Cancer Institute
Healthy Volunteers
Bioavailability of 3 Sildenafil Oral Disintegrating Tablet Formulations Compared to the Standard Oral Tablet
The bioavailability of the oral disintegrating tablet formulations given without water will be similar to an equivalent dose of the standard oral tablet given with water.
- Trial name
- NCT00950404
- Testing
- Viagra 50 mg tablet, Formulation B ODT tablet 50 mg, Formulation C ODT tablet 50 mg
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Recurrent Abortion
Sildenafil Citrate and Recurrent Abortion
Two groups of unexplained recurrent spontaneous abortion, each included 65 participants. scheduled randomly into; the study group received Sildenafil Citrate and Placebo group.
- Trial name
- NCT03475160
- Testing
- Sildenafil Citrate vaginal suppositories, Uterine artery Doppler before treatment, Uterine artery Doppler after treatment
- Volunteers
- 130 people
- Sponsor
- Benha University
Microvascular Coronary Artery Disease
Pharmacodynamic Study to Assess the Effects of Repeated Dosing of SAR247799 on Endothelial Function in Patients With Type 2 Diabetes Mellitus
Primary Objective: To assess the pharmacodynamic effects of SAR247799 on macrovascular endothelial function of the brachial artery using flow-mediated dilation (FMD) in patients with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT03462017
- Testing
- SAR247799, Sildenafil, Acetylcholine
- Where
- 2 sites in Germany
- Volunteers
- 54 people
- Sponsor
- Sanofi
Pulmonary Arterial Hypertension, Hypertension, Pulmonary
Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension
Pulmonary arterial hypertension (PAH) is a rare, progressive, and life-threatening disease. In many patients, the course of PAH is a steady deterioration and reduced life expectancy.
- Trial name
- NCT01642407
- Testing
- Sildenafil
- Where
- 5 sites in Japan
- Volunteers
- 6 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Duchenne Muscular Dystrophy
PDE Inhibitors in DMD Study (Acute Dosing Study)
PDE5A inhibition, which boosts NO-cGMP signaling, will relieve functional muscle ischemia and restore normal blood flow regulation (i.e., functional sympatholysis) during exercise in boys with DMD.
- Trial name
- NCT01580501
- Testing
- Tadalafil and Sildenafil
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Parkinsons Disease, Erectile Dysfunction
Motor Response to Sildenafil in PD
Sildenafil (Viagra(R))is widely used by men with Parkinsons Disease (PD) and erectile dysfunction. A number of patients have reported that when they take Sildenafil, their need of anti-PD medication is reduced.
- Trial name
- NCT01941732
- Testing
- Sildenafil
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Bispebjerg Hospital
Congenital Disorders
Pulmonary Hypertension in Trisomy 21 Patients
Evidence has shown poor outcome for adult patients with pre-operative pulmonary hypertension following closure of an atrial septal defect.
- Trial name
- NCT00478296
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Children's Healthcare of Atlanta
Infertility
Sildenafil Citrate in Frozen Embryo Transfer
Comparison between usage of Sildenafil citrate with estradiol valerate or estradiol valerate alone in endometrial preparation and outcome of frozen-thawed embryo transfer cycles.
- Trial name
- NCT02845388
- Testing
- Sildenafil citrate, estradiol valerate
- Volunteers
- 90 people
- Sponsor
- Omar Ahmed El Sayed Saad
Fontan Circulation
The Effects of Sildenafil on Exercise Function and Capacity in Patients With Fontan Circulation
The study will test the hypothesis that a single dose of sildenafil can increase the exercise capacity of pediatric patients with a Fontan Circulation.
- Trial name
- NCT00964782
- Testing
- Sildenafil, Sildenafil 2
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Alveolitis, Fibrosing, Fibrosis, Pulmonary
Sildenafil Study to Treat Idiopathic Pulmonary Fibrosis
Medicines that decrease blood pressure in the lungs may help idiopathic pulmonary fibrosis (IPF) patients function better. This study will test whether sildenafil improves the ability to exercise in patients with pulmonary…
- Conditions
- Alveolitis, Fibrosing, Fibrosis, Pulmonary, Hypertension, Pulmonary
- Trial name
- NCT00359736
- Testing
- sildenafil
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Pediatric Pulmonary Hypertension
Efficacy of Beraprost in Lowering Pulmonary Arterial Pressure in Children
To analyze the efficacy of beraprost and sildenafil for treatment of pulmonary hypertension in children with left to right shunt. analyze the efficacy and side effects.
- Trial name
- NCT03431649
- Testing
- Beraprost Sodium, Sildenafil Citrate
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Dr. Soetomo General Hospital