Clinical trials: Standard treatment
Treponema Pallidum Infection, Chlamydia Trachomatis Infection
Improving Maternal and Child Health Through Point-of-care STI Testing
The goal of this clinical trial is to learn if point-of-care tests (POCTs) for sexually transmitted infections (STIs) improve the timely treatment of syphilis, chlamydia, gonorrhea, and trichomonas in pregnant women.
- Conditions
- Treponema Pallidum Infection, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginalis Vaginitis
- Trial name
- MATCH-POINT (NCT07290439)
- Testing
- Point-of-care STI tests, Standard of care STI testing
- Where
- United States
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Emory University
Patent Ductus Arteriosus, Preterm
Precision Dosing of Oral Ibuprofen for PDA, A Pilot RCT
Newborns born early are at risk for a serious health problem called patent ductus arteriosus (PDA). PDA is a passageway between heart and lung that can cause life-threatening complications such as bleeding in the brain or even…
- Trial name
- MIPD-PDA (NCT07143201)
- Testing
- Standard Dose - Ibuprofen oral suspension, Precision Dose - Ibuprofen oral suspension
- Where
- Canada
- Volunteers
- 26 people
- Sponsor
- Hamilton Health Sciences Corporation
Cataract
Femtosecond Laser for Cataract Surgery
The objective of this study is to evaluate the safety and efficacy the OptiMedica Femtosecond Laser System, also known as the Catalys™ Precision Laser System, to perform two surgical maneuvers used in the treatment of subjects…
- Trial name
- NCT02110212
- Testing
- U/S Surgery and CCC, FS Laser Surgery
- Volunteers
- 17 people
- Sponsor
- Abbott Medical Optics
Autism Spectrum Disorder, Autism
Safety and Efficacy of the Transfusion of UCB in Patients With an ASD Depending on the Degree of HLA Compatibility.
Autism is one of those disorders in Autism spectrum disorders (ASD), which characterized by social interaction abnormalities, impaired verbal and non-verbal communication, and repetitive, obsessive behavior, while the therapeutic…
- Trial name
- ASD-HLA2019 (NCT04099381)
- Testing
- ASD CB-MNC infusion low level HLA compatibility., ASD CB-MNC infusion high level HLA compatibility., Standard therapy.
- Where
- Russia
- Volunteers
- 150 people
- Sponsor
- State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Cutaneous Leishmaniasis
Reduced Doses of Antimony Plus Ranulocyte Monocyte Colony Stimulating Factor (GM-CSF) for Cutaneous Leishmaniasis
The present study was designed as a randomized, single blind, placebo-controlled, study to evaluate the effect of 400 µg of recombinant human GM-CSF applied intralesionally and associated with half of the total dose of antimony…
- Trial name
- GMCSFSbv (NCT00973128)
- Testing
- GMCSF plus Antimony reduced dose, Meglumine antimoniate
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Hospital Universitário Professor Edgard Santos
Dietary Supplementation, Severe Acute Malnutrition
Safety Trial of F-60 Among Children Hospitalized With SAM
The current WHO-recommended F-75 diet for stabilization of SAM has remained largely unchanged since its development in the 1990s.
- Conditions
- Dietary Supplementation, Severe Acute Malnutrition, Children
- Trial name
- NCT07752628
- Testing
- F75 milk feeds, F60 milk feeds
- Where
- Bangladesh
- Volunteers
- 320 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Hepatitis, Autoimmune, Primary Biliary Cholangitis
Mycophenolate Mofetil Versus Cyclosporin A in the Treatment of Primary Biliary Cholangitis-autoimmune Hepatitis Overlap Syndrome Due to Nonresponse to Standard Therapy
Biochemical response of primary biliary cholangitis-autoimmune hepatitis overlap syndrome induced by mycophenolate mofetil versus cyclosporin A
- Conditions
- Hepatitis, Autoimmune, Primary Biliary Cholangitis, Immunosuppression
- Trial name
- NCT04376528
- Testing
- Cyclosporin A, Mycophenolate Mofetil
- Where
- China
- Volunteers
- 89 people
- Sponsor
- West China Hospital
Post-traumatic Stress Disorder, Depression
SimCoach Evaluation: A Virtual Human Intervention to Encourage Servicemember Help-seeking for PTSD and Depression
SimCoach, a computer program featuring a virtual human that speaks and gestures in a videogame-like interface, is designed to encourage servicemembers, especially those with signs or symptoms of post-traumatic stress disorder…
- Trial name
- NCT02335528
- Testing
- SimCoach
- Volunteers
- 333 people
- Sponsor
- RAND
Chronic Kidney Disease
Impact of Curcumin and Pentoxiphylline on Chronic Kidney Disease Patients
The aim of the study is to evaluate the impact of turmeric and pentoxiphylline on serum levels of protein-bound uremic toxin (p-cresyl sulfate), oxidative stress biomarker level (Malonaldehyde), inflammatory biomarker level…
- Trial name
- CKD (NCT06458465)
- Testing
- Curcumin, Pentoxifylline 400 MG
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Wrist Fractures, Distal Radius Fractures
Unilateral Training of the Uninjured Limb on Clinical Outcomes in Patients with Surgically Treated Radius Fracture
The objective will be to determine the effectiveness of adding unilateral upper limb postoperative training to standard rehabilitation compared to standard rehabilitation on maximum grip strength and manual dexterity in patients…
- Trial name
- NCT06698367
- Testing
- Standard rehabilitation, Unilateral high-intensity strength exercise, Unilateral mobility exercises
- Where
- Chile
- Volunteers
- 52 people
- Sponsor
- Universidad Catolica de Temuco
Fatigue
PG2 Treatment for Improving Fatigue Among Advanced Cancer Patients Under Standard Palliative Care
The objective of this study is to conduct a trial in the spirit of providing as much as possible the benefit of PG2 treatment to eligible patients and to evaluate the efficacy and safety of PG2 for relieving fatigue among…
- Trial name
- NCT00523107
- Testing
- PG2
- Where
- Taiwan
- Volunteers
- 91 people
- Sponsor
- PhytoHealth Corporation
Stroke
Feasibility of a Home Hazard Management Program for Malaysian Stroke Survivors
This quasi experimental design study aims to examine the feasibility and potential effectiveness of a home hazard management program to reduce the rate of falls and fear of falling among Malaysian community dwelling stroke…
- Trial name
- NCT04618029
- Testing
- Home Modification, Education
- Where
- 3 sites in Malaysia
- Volunteers
- 30 people
- Sponsor
- Universiti Putra Malaysia
No-Reflow Phenomenon
Alpha Lipoic Acid Effect on No-Reflow Phenomenon
Prospective, randomized, open-label, controlled clinical trial to evaluate the efficacy and tolerability of Alpha Lipoic Acid administration on oxidative stress, inflammatory markers, clinical outcome and occurrence of No-Reflow…
- Trial name
- NCT05360602
- Testing
- Alpha Lipoic Acid plus the standard care for post-PCI MI, The standard care for post-PCI MI
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Renal Cell Carcinoma, Urinary Bladder Neoplasms
Phase I/Ib Study of Pembrolizumab With Vorinostat for Patients With Advanced Renal or Urothelial Cell Carcinoma
Primary objective: To assess the early signals for anti-tumor activity (i.e. objective response rate, progression-free survival) of pembrolizumab in combination with vorinostat in patients with advanced prostate, renal or…
- Trial name
- NCT02619253
- Testing
- Pembrolizumab, Vorinostat
- Where
- 4 sites in United States
- Volunteers
- 52 people
- Sponsor
- Nabil Adra
Breast Neoplasm, Colorectal Neoplasm
Decision Aid Website in Helping to Make Decisions About Fertility in Participants With Cancer
This trial studies how well a decision aid website works in helping to make decisions about fertility in participants with cancer.
- Conditions
- Breast Neoplasm, Colorectal Neoplasm, Female Reproductive System Neoplasm, Health Care Provider
- Trial name
- NCT03141437
- Testing
- Best Practice, Educational Intervention, Internet-Based Intervention
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- M.D. Anderson Cancer Center
Literacy
Occupational Therapy-based Literacy Intervention and Classroom Based Literacy Intervention
The purpose of this study is to determine the impact of a literacy focused occupational therapy intervention program versus standard classroom-based reading intervention on reading engagement and reading achievement in elementary…
- Trial name
- NCT03975972
- Testing
- Occupational Therapy Based Literacy Intervention
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Head and Neck Cancer
Quality-Of-Life Assessment in Patients With Head and Neck Cancer Treated With Radiation Therapy
RATIONALE: Gathering information over time about patients' quality-of-life and satisfaction with care may help doctors plan the best treatment and help patients live more comfortably.
- Trial name
- NCT01210872
- Testing
- questionnaire administration, quality-of-life assessment, standard follow-up care
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Georges Francois Leclerc
Helminthiasis, Nematode Infection
Impact of Alternative Treatment Strategies and Delivery Systems for Soil-transmitted Helminths in Kenya
The mainstay of control of soil-transmitted helminths (STH) is school-based deworming but recent modelling has highlights that in all but low very transmission settings, the treatment of school-aged children is unlikely to…
- Conditions
- Helminthiasis, Nematode Infection, Disease Transmission, Infectious
- Trial name
- TUMIKIA (NCT02397772)
- Testing
- albendazole
- Where
- Kenya
- Volunteers
- 21,761 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Anesthesia, General, Surgery
Physiological Effects of Lung Recruitment During General Anesthesia and Low-tidal Volume Ventilation
Low-tidal volume ventilation is arising as a tool to optimize the ventilatory management and to improve clinical outcome in patients undergoing general anesthesia for abdominal surgery.
- Trial name
- PEEP-RM (NCT03083457)
- Testing
- Fluid resuscitation or amine administration, General anesthetic, Fluid administration
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Catholic University of the Sacred Heart
Breast Cancer, Sedentary Lifestyle
Developing a Healthy Lifestyle in Breast Cancer Survivors
At this time, no study has examined the effect of a lifestyle intervention with a reduced Sedentary Behavior (SB) prescription on overall physical activity, weight loss, metabolic dysfunction, and inflammation in breast cancer…
- Trial name
- NCT02677857
- Testing
- Common intervention components for Lifestyle
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.