Clinical trials: Stereotactic Body Radiation Therapy
Ventricular Arrythmia
SBRT for Ventricular Arrhythmia
The aim of this study is to demonstrate the safety and efficacy of STAR (Stereotactic Antiarrhythmic Radiotherapy) in patients with VT (ventricular tachycardia) who are unresponsive to standard treatments.
- Trial name
- NCT06411392
- Testing
- Stereotactic Antiarrhythmic Radiotherapy
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Graz
Metastatic Colorectal Cancer
Radiosensitizing Chemotherapy withSBRT for the Treatment of Inoperable Liver and/or Lung Metastases of CRC
The purpose of this study is to study stereotactic radiotherapy with a dose of 40 Gy in 4 fractions over 2 weeks with concomitant 40 mg/m2 of irinotecan (1st and 3rd irradiation session).
- Trial name
- RSCAMPTO (NCT01220063)
- Testing
- Radiation, Irinotecan
- Where
- 6 sites in France
- Volunteers
- 47 people
- Sponsor
- Institut Cancerologie de l'Ouest
Non Small Cell Lung Cancer
Durvalumab and Stereotactic Radiotherapy for Advanced NSCLC
This is a randomized Phase II study which is designed to determine the impact of stereotactic radiotherapy and durvalumab on quality-of-life and oncologic outcomes in patients with advanced non-small cell lung cancer.
- Trial name
- NCT04786093
- Testing
- Stereotactic radiation therapy, Durvalumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Texas Southwestern Medical Center
Hepatocellular Carcinoma
The Efficacy of Transarterial Chemoinfusion (TAI) Combine Stereotactic Body Radiation Therapy (SBRT) in Unresectable Hepatocellular Carcinoma (HCC)
To evaluate the efiicacy of TAI combine SBRT in unresectable HCC
- Trial name
- NCT03851887
- Testing
- TAI combine SBRT
- Where
- China
- Volunteers
- 33 people
- Sponsor
- Sun Yat-sen University
Brain Metastases
Preoperative Stereotactic Radiosurgery for Brain Metastases
STEP is a French multicentre, prospective, non-randomized, phase II study designed to assess 6-months local control after pre-operative stereotactic radiosurgery (SRS) for patients with brain metastases
- Trial name
- STEP (NCT04503772)
- Testing
- Preoperative SRS
- Where
- 8 sites in France
- Volunteers
- 70 people
- Sponsor
- Centre Jean Perrin
Hepatocellular Carcinoma
RFA vs. SBRT for Small HCC
Hepatocellular carcinoma (HCC) is one of the malignant tumors that seriously threaten the health of people. Its morbidity and mortality rank the third and the second among various malignant tumors in China, respectively.
- Trial name
- NCT03898921
- Testing
- stereotactic body radiotherapy (SBRT), Radiofrequency ablation (RFA)
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Sun Yat-sen University
Decision Making, Shared, Stereotactic Body Radiation Therapy
Shared Decision Making on Radiation Dose for Lung Malignancies
A Patient Decision Aid (PtDA) is developed during a workshop in close collaboration with selected patients. The PtDA is subsequently used in the consultation between patient and physician to facilitate their shared decision on…
- Conditions
- Decision Making, Shared, Stereotactic Body Radiation Therapy, Lung Cancer, Non-small Cell, Radiation Toxicity
- Trial name
- NCT04940936
- Testing
- A Patient Decision Aid
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Vejle Hospital
Head and Neck Cancer
Cetuximab and Stereotactic Radiation Therapy in Treating Patients With Recurrent Head and Neck Cancer That Cannot Be Removed By Surgery
RATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.
- Trial name
- CKNO-RERT (NCT00738868)
- Testing
- cetuximab, stereotactic body radiation therapy
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Centre Oscar Lambret
Lung Carcinoma, Lung Non-Small Cell Carcinoma
Using an Artificial Intelligence Software Tool (iSeg) During Radiation Treatment Planning for Patients With Lung Tumors
This clinical trial studies whether an artificial intelligence (AI) software tool called iSeg can be safely and effectively used during routine radiation treatment planning for patients with lung tumors.
- Conditions
- Lung Carcinoma, Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Lung
- Trial name
- NCT07898241
- Testing
- Artificial Intelligence-based Intervention, Best Practice, Computed Tomography
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Northwestern University
Metastatic Cancer, Unspecified Adult Solid Tumor, Protocol Specific
Stereotactic Radiosurgery in Treating Patients With Liver Metastases, Lung Metastases, or Other Advanced Solid Tumors
RATIONALE: Stereotactic radiosurgery delivers x-rays directly to the tumor and may cause less damage to normal tissue. PURPOSE: Phase II trial to study the effectiveness of stereotactic radiosurgery in treating patients who have…
- Trial name
- NCT00006456
- Testing
- stereotactic radiosurgery
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Virginia Commonwealth University
Brain Metastases
Phase I Study of Fractionated Stereotactic Radiation Therapy
There is a lack of prospective trial data and consensus guidelines describing the use of Fractionated Stereotactic Radiation Therapy (FSRT) in the treatment of brain metastases.
- Trial name
- NCT03726359
- Testing
- Fractionated Stereotactic Radiation Therapy (FSRT)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Albert Einstein College of Medicine
Extensive-stage Small-cell Lung Cancer
Adaptive SBRT Plus Chemoimmunotherapy for ES-SCLC
This is trial studying the safety of adaptive stereotactic body radiotherapy (SBRT) combined with durvalumab immunotherapy, platinum chemotherapy, and etoposide chemotherapy in platinum refractory extensive stage small cell lung…
- Trial name
- NCT05403723
- Testing
- Durvalumab 50 MG/1 ML Intravenous Solution, Etoposide Injection, Cisplatin
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Maryland, Baltimore
Lung Cancer
Stereotactic Body Radiation Therapy in Treating Patients With Stage I or Stage II Non-Small Cell Lung Cancer That Can Be Removed By Surgery
RATIONALE: Stereotactic body radiation therapy may be able to send x-rays directly to the tumor and cause less damage to normal tissue near the tumor.
- Trial name
- NCT00551369
- Testing
- SBRT
- Where
- 19 sites in United States
- Volunteers
- 33 people
- Sponsor
- Radiation Therapy Oncology Group
TNBC
A Single-Arm, Single-Center, Phase II Clinical Study of Camrelizumab Combined With Radiochemotherapy as Neoadjuvant Therapy for Early-Stage Triple-Negative Breast Cancer
Camrelizumab + Chemoradiotherapy for Early TNBC Sponsor/Leading Center: Tianjin Medical University Cancer Institute and Hospital Study Type: Single-arm, single-center, Phase Ⅱ clinical study Planned Enrollment: 43 patients…
- Trial name
- NCT07491822
- Testing
- treatment group
- Volunteers
- 43 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Glioblastoma Multiforme
Trial of Anti-PD-1 Immunotherapy and Stereotactic Radiation in Patients With Recurrent Glioblastoma
The purpose of this study is to assess the safety/tolerability/feasibility of pembrolizumab and radiation therapy before surgical resection in patients with recurrent glioblastoma as defined by treatment-related AEs and the…
- Trial name
- NCT04977375
- Testing
- Pembrolizumab, Stereotactic Radiation Therapy, Surgical Resection
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Chirag G. Patil
Carcinoma, Hepatocellular, Hepatobiliary Neoplasm
Combination SBRT With TACE for Unresectable Hepatocellular Carcinoma
To determine the efficacy and toxicity of TACE combined with SBRT
- Conditions
- Carcinoma, Hepatocellular, Hepatobiliary Neoplasm, Liver Carcinoma
- Trial name
- NCT01020812
- Testing
- TACE, SBRT
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Stanford University
Early Stage Breast Cancer
Cyberknife for Early Stage Breast Cancer
This phase II study based on the Cyberknife Society study will evaluate the technical feasibility and acute toxicity of Partial Breast Irradiation (PBI) with the Cyberknife.
- Trial name
- NCT03946683
- Testing
- Cyberknife for Early Stage Breast Cancer
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- NYU Langone Health
Biliary Tract Cancer, Radiotherapy
COmbination of Radiotherapy With Anti-PD-1 Antibody for unREseCtable Biliary Tract Cancer
The study is a single-arm, phase II trial. The purpose is to investigate both the efficacy and safety of radiotherapy combined with anti-PD-1 antibody in unresectable biliary tract cancer patients.
- Conditions
- Biliary Tract Cancer, Radiotherapy, Immunotherapy
- Trial name
- CORRECT (NCT03898895)
- Testing
- Radiotherapy+anti-PD-1 antibody
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Sun Yat-sen University
Adenocarcinoma of the Prostate
Radiation and Androgen Ablation for Prostate Cancer
A study to see how effective and tolerable radiation therapy along with androgen deprivation therapy is in treating prostate cancer.
- Trial name
- NCT01517451
- Testing
- Radiation Therapy, Androgen Deprivation Therapy (ADT)
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Non-small Cell Lung Cancer
The Utility of PET/CT in the Planning of Stereotactic Body Radiotherapy for Non-small Cell Lung Cancer
The trial evaluates the utility of 18FDG-PET/CT scan in the target definition process when SBRT is planned for stage I NSCLC.
- Trial name
- NCT00380666
- Testing
- PET/CT scan
- Sponsor
- University of Aarhus
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