Clinical trials: Stereotactic Body Radiation Therapy
Lung Cancer, Left Sided Breast Cancer
A Prospective Study to Evaluate Continuous Positive Airway Pressure Devices to Reduce Pulmonary Dose
Data collection and assessment on patients with left-sided breast cancer or undergoing lung stereotactic body radiation therapy (SBRT) utilizing continuous positive airway pressure (CPAP) devices.
- Trial name
- NCT05142358
- Testing
- Continuous Positive Airway Pressure, Deep inspiratory breath hold, Free Breath
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Case Comprehensive Cancer Center
Prostate Cancer
Erectile Dysfunction in Good Prognosis Prostate Cancer : Comparison Between Brachytherapy and Stereotactic Body Radiotherapy
The TEMPOS-GEniToUrinary Group (GETUG) study is a multicenter, medico-economic study comparing brachytherapy to SBRT in low and intermediate risk prostate cancer, particularly focused on the issue of erectile dysfunction.
- Trial name
- TEMPOS (NCT03830788)
- Testing
- Radiation by brachytherapy, Radiation by SBRT
- Where
- 20 sites in France
- Volunteers
- 240 people
- Sponsor
- Center Eugene Marquis
Metastatic Cancer
A Study to Assess the Ability of Stereotactic Radiotherapy to Restore the Efficacy of Immunotherapy in Patients With Metastatic Cancer.
This study aims at enrolling patients with solid tumors at metastatic stage, considered long responders to immunotherapy (> 6 months) and displaying disease progression.
- Trial name
- RESTO-IMMUNO (NCT06363773)
- Testing
- Stereotactic Radiotherapy
- Where
- France
- Volunteers
- 35 people
- Sponsor
- Elsan
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8
Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer
This phase I trial evaluates the best dose, possible benefits and/or side effects of combination therapy with elimusertib (BAY 1895344), stereotactic body radiation, and pembrolizumab in treating patients with head and neck…
- Conditions
- Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8, Recurrent Head and Neck Cutaneous Squamous Cell Carcinoma, Recurrent Head and Neck Squamous Cell Carcinoma
- Trial name
- NCT04576091
- Testing
- Biospecimen Collection, Computed Tomography, Elimusertib
- Where
- 11 sites in United States
- Volunteers
- 7 people
- Sponsor
- National Cancer Institute (NCI)
Pancreatic Cancer
Cone-beam CT Guided Stereotactic Radiation Therapy for Locally Advanced Pancreatic Cancer
Pancreatic cancer has a very poor survival, due to late diagnosis and lack of sufficient treatment options for locally advanced tumors and metastasized patients.
- Trial name
- NCT01898741
- Testing
- 24 Gy in 3 fractions
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- UMC Utrecht
Recurrent Prostate Cancer After Surgery
This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
There is significant, proven use of radiation for recurrent prostate cancer after surgical resection. This treatment typically is delivered over seven and a half weeks of daily treatments, presenting a burden to patients and the…
- Trial name
- DASBRT-RPC (NCT05946824)
- Testing
- Daily-adaptive Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Recurrent Hepatocellular Carcinoma, Stage I Hepatocellular Carcinoma AJCC v8
Stereotactic Body Proton Radiotherapy for the Treatment of Liver Cancer
This phase II trial studies the effect of stereotactic body proton radiotherapy in treating patients with liver cancer. Proton radiotherapy is a type of treatment that uses high-energy beams to treat tumors.
- Conditions
- Recurrent Hepatocellular Carcinoma, Stage I Hepatocellular Carcinoma AJCC v8, Stage II Hepatocellular Carcinoma AJCC v8, Stage III Hepatocellular Carcinoma AJCC v8
- Trial name
- NCT04805788
- Testing
- Proton Stereotactic Body Radiation Therapy, Quality-of-Life Assessment
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- Mayo Clinic
Spinal Metastases, Spinal Tumors
SBRT Technique Implementation for Spinal Metastases Irradiation
Stereotactic body radiotherapy (SBRT) is a highly precise, image-guided radiotherapy technique delivering 1-5 high-dose fractions to spinal metastases.
- Conditions
- Spinal Metastases, Spinal Tumors, Bone Metastases
- Trial name
- NCT07429422
- Testing
- Stereotactic Body Radiotherapy (SBRT) for Spinal Metastases
- Where
- 2 sites in Slovenia
- Volunteers
- 100 people
- Sponsor
- Institute of Oncology Ljubljana
Head and Neck Cancer
Surgery With or Without Adjuvant Stereotactic Body Radiotherapy
Comparison of patients with operable, recurrent previously-irradiated squamous cell head-and-neck cancers with or without adjuvant SBRT.
- Trial name
- NCT02516969
- Testing
- Stereotactic Body Radiotherapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- David A. Clump, MD, PhD
Early-stage Breast Cancer
Adjuvant Partial-breast Irradiation Using Stereotactic Body Radiation Therapy
The adjuvant radiotherapy (RT) of the early-stage breast cancer patients as local treatment aims to eliminate the potential microscopic residual disease in the surgery bed or satellites in its neighborhood.
- Trial name
- NCT06007118
- Testing
- APBI, WBI
- Where
- Czechia
- Volunteers
- 85 people
- Sponsor
- Masaryk Memorial Cancer Institute
Lung Cancer, Non Small Cell Lung Cancer
Phase II Study of Stereotactic Body Radiation Therapy Using Tomotherapy for Tumors of the Lung
The purpose of this study is to determine the response of lung tumors to radiation therapy. This study will be using a type of radiation therapy called tomotherapy.
- Conditions
- Lung Cancer, Non Small Cell Lung Cancer, Solid Tumors
- Trial name
- NCT00832780
- Testing
- Stereotactic Body Radiation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- New Mexico Cancer Research Alliance
Breast Cancer, Breast Cancer Stage II
Neoadjuvant, SBRT With Intratumoural Pembrolizumab Followed by Neoadjuvant Chemotherapy in Breast Cancer
This study will evaluate the immune-priming effects of stereotactic body radiation therapy (SBRT) regimen coupled with two injections of pembrolizumab in high-risk primary breast carcinoma prior to neoadjuvant chemotherapy.
- Conditions
- Breast Cancer, Breast Cancer Stage II, Breast Cancer Stage III, Breast Cancer Invasive
- Trial name
- BRINK (NCT07188246)
- Testing
- Radiation, Pembrolizumab (KEYTRUDA®)
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Adenoid Cystic Carcinoma, Oligometastatic
Phase II Trial Comparing Stereotactic Body Radiotherapy Versus Active Surveillance for Oligometastatic Adenoid Cystic Carcinoma
The SABR Oligo-ACC Trial is a randomized phase II study comparing early initiation of SBRT to all metastases versus active surveillance in patients with oligometastatic ACC.
- Trial name
- NCT07845097
- Testing
- Stereotactic body radiotherapy (SBRT)
- Volunteers
- 90 people
- Sponsor
- All India Institute of Medical Sciences
Lung Cancer (NSCLC), Geriatric Assessment
Practical Geriatric Assessment in Older Adults With Non-Small Cell Lung Cancer Undergoing Stereotactic Body Radiation Therapy
National guidelines recommend that older adults with cancer undergo a special health assessment before starting cancer treatment.
- Conditions
- Lung Cancer (NSCLC), Geriatric Assessment, Stereotactic Body Radiation Therapy (SBRT)
- Trial name
- Lung-GAP (NCT06987890)
- Testing
- Practical Geriatric Assessment
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Brigham and Women's Hospital
Renal Cancer Metastatic
Nivolumab Plus Stereotactic Body Radiotherapy in II and III Line of Patients With Metastatic Renal Cell Carcinoma
NIVES study is an ongoing phase II, single arm, multicenter study. In this trial pts received SBRT to one non-brain measurable lesion and concomitant NIVOLUMAB, an anti-programmed cell death (PD-1).
- Trial name
- NIVES (NCT03469713)
- Testing
- Nivolumab
- Where
- Italy
- Volunteers
- 69 people
- Sponsor
- Gruppo Oncologico Italiano di Ricerca Clinica
Pancreatic Cancer, Stereotactic Body Radiotherapy
Improving REsectability in Pancreatic NEoplasms (IRENE)
Evaluation of clinical response in terms of resectability of patients with locally advanced pancreatic cancer treated with neoadjuvant chemotherapy plus stereotactic body radiotherapy.
- Trial name
- IRENE (NCT03460925)
- Testing
- SBRT plus chemotherapy
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Metastasis to Bone, Radiotherapy
A Trial to Improve Quality of Life With Stereotactic Body Radiotherapy for Patients With Painful Bone Metastases
This is a phase III randomized-controlled, single-blind study comparing the standard schedule for antalgic radiotherapy of a single fraction of 8.0 Gy delivered through three-dimensional conformal radiotherapy (3D-CRT) to a…
- Conditions
- Metastasis to Bone, Radiotherapy, Neoplasm Metastasis
- Trial name
- ROBOMET (NCT03831243)
- Testing
- Stereotactic body radiotherapy, 3D-conformal radiotherapy
- Where
- Belgium
- Volunteers
- 126 people
- Sponsor
- Cancer Research Antwerp
Uterine Cervical Neoplasm
Cervical Boost by Ablative Stereotactic Radiotherapy (SABR) vs Brachytherapy in Patients With Cervical Carcinoma
Background Cervical cancer (CaCu) is the fourth cause of death in women. In patients with locally advanced disease, the treatment of choice is CT/RT, followed by additional boosting with brachytherapy (BT).
- Trial name
- SABRVICAL (NCT06560697)
- Testing
- SABR VS Intracavitary 3D Brachytherapy
- Where
- Mexico
- Volunteers
- 84 people
- Sponsor
- National Institute of Cancerología
Non-small Cell Lung Cancer
Stereotactic Body Radiation Therapy for Inoperable Locally-advanced Non-small Cell Lung Cancer
The purpose of this study is to determine if the use of exploratory immunologic biomarkers, functional MRI images can serve as early predictors for response of NSCLC.
- Trial name
- NCT01899989
- Testing
- Stereotactic Body Radiation Therapy (SBRT), cisplatin or carboplatin-based
- Where
- 8 sites in United States
- Volunteers
- 39 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Inoperable Locally Advanced Non Small Cell Lung Cancer
Combined CFRT and SABR in Stage II and III NSCLC With Peripheral Tumors Smaller Than 5 cm.
A phase I trial is being conducted in patients with inoperable locally advanced NSCLC to treat with a combination of Conventional Fractionated Radiotherapy (CFRT) on the mediastinal lymph nodes and Stereotactic Ablative…
- Trial name
- N12HYB (NCT01933568)
- Testing
- SABR, Cisplatin
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- The Netherlands Cancer Institute
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.