Clinical trials: Transcranial Direct Current Stimulation, completed
Alzheimer Disease, Mild Cognitive Impairment
Evaluation of the Effectiveness and Safety of Transcranial Direct Current Stimulation in Combination With Nasal Near Infrared Stimulation to Improve Cognitive Functions and Quality of Life in Elderly People With Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD).
Alzheimer's disease (AD) and mild cognitive impairment (MCI) are progressive neurodegenerative conditions with limited therapeutic options. Today, around 30 million people worldwide suffer from Alzheimer's dementia.
- Trial name
- NCT07290686
- Testing
- tDCS stimulation, tDCS, iNIRS stimulation
- Where
- Poland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Parkinson Disease
Transcranial Direct Current Stimulation to Treat Symptoms of Parkinson's Disease
This study will examine the effects of transcranial direct current stimulation (tDCS) on gait (walking) problems and rigidity in patients with Parkinson's disease.
- Trial name
- NCT00082342
- Testing
- Phoressor II (IOMED)
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke, Upper Extremity Paresis
NIBS With mCIMT for Motor and Functional Upper Limb Recovery in Stroke Patients.
Stroke is one of the leading causes of serious long-term impairment. According to the estimates, 12,500 people suffer a new or recurrent ischemic stroke in Chile annually, which shows the magnitude of the problem.
- Conditions
- Stroke, Upper Extremity Paresis, Electric Stimulation, Occupational Therapy
- Trial name
- NCT03452254
- Testing
- Active Bihemispheric Transcranial direct current Stimulation, Modified Constraint Induced Movement Therapy
- Where
- 2 sites in Chile
- Volunteers
- 70 people
- Sponsor
- University of Chile
Upper Extremity Dysfunction, Traumatic Brain Injury
Targeted Noninvasive Brain Stimulation (T-NIBS) to Improve Hand Motor Functions in Acquired Brain Injury
Acquired Brain Injury (TBI) is a serious medical and health problem in the US. Individuals with an acquired brain injury due to stroke and Traumatic Brain Injury (TBI) commonly suffer from upper extremity physical impairments…
- Trial name
- NCT04057105
- Testing
- Active High-definition Transcranial Direct Current Stimulation (HD-tDCS), MusicGlove
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Kessler Foundation
Tobacco Use Disorder
Effect of Transcranial Direct Current Stimulation (tDCS) on Tobacco Consumption
The primary purpose of the protocol is to evaluate the effect of repeated application for 5 consecutive days of a real tDCS compared to the application of a placebo tDCS (sham procedure) on the evolution of tobacco consumption in…
- Trial name
- TABELEC (NCT01930422)
- Testing
- tDCS procedure
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Toulouse
Cerebral Stroke
Enhancement of Motor Function with Reboxetine and Transcranial Direct Current Stimulation
The hypothesis of the study is that combination of reboxetine/tDCS is more effective in enhancing motor functions of daily life (assessed by the Jebsen Taylor test) as compared to reboxetine and tDCS alone.
- Trial name
- STIMBOX (NCT00853866)
- Testing
- reboxetine, tDCS verum
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Post-stroke Depression
Transcranial Direct Current Stimulation on Post Stroke Depression
The aim of the research is to address the critical gap that limited number of RCTs are conducted on this topic. To further explore the efficacy of tDCs, large sample sizes, large follow up period and rigorously controlled…
- Trial name
- NCT06598670
- Testing
- tDCS, Conventional treatment
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Alzheimer Disease
tACS for Amyloid-β Reduction in Alzheimer's Disease
Alzheimer's Disease (AD) is characterized by amyloid-β (Aβ) plaque buildup and phosphorylated tau (p-tau) in the brain, as well as widespread neurodegeneration.
- Trial name
- NCT03290326
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Massachusetts General Hospital
Stroke
Efficacy of TOCT and (tDCS) for Gait Improvement in Patients With Chronic Stroke
Stroke is one of the major causes of disability in the Western world. Initially gait is the most affected function, 80% of patients lose this ability.
- Trial name
- NCT01883843
- Testing
- real tDCS + TOCT
- Where
- Italy
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Attention Deficit/Hyperactivity Disorder
Non Invasive Brain Stimulation Effects on Attentional Performance in ADHD Adults
This study aims to evaluate the effect of noninvasive brain stimulation in adults with ADHD symptomatology compared them with healthy adults.
- Trial name
- NCT02286349
- Testing
- Transcranial magnetic stimulation (Neurosoft®), Transcranial direct current stimulation (Soterix, USA)
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Stroke
Association Between the tDCS and FDS for Gait Rehabilitation After Stroke
The aim of this study is to verify the effectiveness of tDCS combined with foot drop stimulation (FDS) on gait rehabilitation of post-stroke subjects with mild and moderate compromise.
- Trial name
- NCT04077814
- Testing
- Foot Drop Stimulatio - Neuro Orthosis, Transcranial direct brain stimulation
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Hemiparesis, Cerebrovascular Disorders
Mechanized Gait Trainer Combine Transcranial Galvanic Stimulation (tDCS) in Chronic Stroke
Transcranial galvanic stimulation (tDCS), seems to promote motor recovery after stroke by stimulating (anodal) or inhibiting (cathodal) neural circuits in the brain.
- Trial name
- GT-1-tDCS (NCT01040299)
- Testing
- GangTrainer and tDCS, control group1, Control group2
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Universita di Verona
Pain
Effects of Transcranial Direct Current Stimulation on Pain Perception
The purpose of this study is to determine whether a new medical technology can temporarily alter pain perception. The new technology is called Transcranial direct current stimulation (tDCS).
- Trial name
- tDCS-CBT (NCT01860950)
- Testing
- anodal tDCS, cathodal tDCS
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Chronic Low-back Pain
Effects of tDCS on Heart Rate Variability in Chronic Low Back Pain
Chronic low back (CLBP) pain is an important public health and socioeconomic problem worldwide and, despite the volume of research in the area, it remains a difficult condition to treat.
- Trial name
- NCT04077632
- Testing
- Transcranial direct current stimulation
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal do Piauí
Recovery Methods, Muscle Fatigue
Combined tDCS and Pneumatic Compression for Recovery After a 10K Run
This study will examine how two recovery methods-pneumatic compression (PC) applied to the legs and transcranial direct current stimulation (tDCS) applied to the head-help athletes recover after a 10-kilometer (10K) run.
- Conditions
- Recovery Methods, Muscle Fatigue, Exercise Performance Recovery, Endurance Exercise
- Trial name
- NCT07333404
- Testing
- Transcranial Direct Current Stimulation (tDCS), Normatec Pneumatic Compression
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Uludag University
Aphasia
Transcranial Direct Current Stimulation Investigations of Language Processing in Aphasia
This study proposes to use transcranial direct current stimulation (tDCS) in patients with chronic strokes and aphasia in order to characterize and enhance the mechanisms of language recovery following injury.
- Trial name
- NCT04041986
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Volunteers
- 25 people
- Sponsor
- University of Pennsylvania
Transcranial Direct Current Stimulation, Functional Magnetic Resonance Imaging
High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Early Alzheimer's Disease
This completed randomized trial evaluated the clinical and neural effects of high-definition transcranial direct current stimulation (HD-tDCS) combined with computerized cognitive training in patients with Alzheimer's disease.
- Conditions
- Transcranial Direct Current Stimulation, Functional Magnetic Resonance Imaging, Early Alzheimer's Disease
- Trial name
- HD-tDCS (NCT04599764)
- Testing
- HD-tDCS, computer-based cognitive training, Control cognitive training
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Stroke, Acute
Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke
This proposal is a prospective, single-center, dose-escalation safety, tolerability, feasibility and potential efficacy study of transcranial direct current stimulation (tDCS) in acute stroke patients with substantial salvageable…
- Trial name
- TESSERACT (NCT03574038)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Obsessive-compulsive Disorders and Symptoms
tDCS Stimulation to Treat Patients With Severe and Resistant Obsessive Compulsive Disorder-Pilot Study
The purpose is to show that bifocal tDCS with an anodal stimulation on the orbitofrontal cortex and cathodic stimulation on supplementary motor areas is an effective treatment for patients with resistant and severe obsessive…
- Trial name
- tDCS-TOC (NCT03284671)
- Testing
- bifocal stimulation with tDCS
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Henri Laborit
Aphasia
NOn-invasive Repeated THerapeutic STimulation for Aphasia Recovery
The current standard of care for rehabilitation of patients with aphasia after stroke is conventional speech and language therapy (SLT).
- Trial name
- NORTHSTAR (NCT02020421)
- Testing
- rTMS, tDCS
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 63 people
- Sponsor
- Dr. Alexander Thiel