Clinical trials: Transcranial Direct Current Stimulation
Brain Diseases, Central Nervous System Diseases
Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Upper Limb Recovery in Patients With Stroke
Following a stroke, the function of the distal upper limb, especially hand and finger movements, is often severely compromised, significantly restricting the ability to carry out daily activities.
- Conditions
- Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Stroke
- Trial name
- bi-tDCS+VR (NCT07288385)
- Testing
- Transcranial Direct Current Stimulation combined with virtual reality
- Where
- Saudi Arabia
- Volunteers
- 100 people
- Sponsor
- King Saud University
Hemiplegic Cerebral Palsy, Perinatal Stroke
Robotic Rehabilitation and Brain Stimulation for Children With Hemiparetic Cerebral Palsy
This study evaluates the use of robotic rehabilitation with and without transcranial direct current stimulation (tDCS) to improve motor performance in children with hemiparetic cerebral palsy.
- Trial name
- RoboCP (NCT04233710)
- Testing
- Robot Rehabilitation + tDCS
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Transcranial Alternating Current Stimulation, Alzheimer Disease (AD)
Transcranial Alternating Current Stimulation (tACS) Combined With Cognitive Training in Alzheimer's Disease
The aim of the study is to evaluate the clinical and biological efficacy, as well as predictors of efficacy, of a home-based intervention combining transcranial alternating current stimulation (tACS) with individualized…
- Conditions
- Transcranial Alternating Current Stimulation, Alzheimer Disease (AD), Alzheimer Dementia (AD), Cognitive Rehabilitation
- Trial name
- AD_tACSrehab (NCT07839650)
- Testing
- Transcranial Alternating Current Stimulation, Individualized Computerized Memory Training
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Disorder of Consciousness
tACS Alters EEG Microstates in DoC
Disorders of consciousness (DoC), including unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS), remain difficult to diagnose at the bedside.
- Trial name
- NCT07699055
- Testing
- Transcranial Alternating Current Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people
- Sponsor
- Istanbul Medipol University Hospital
Traumatic Brain Injury
Spectral Correlates of Impulsivity in Patients With Traumatic Brain Injury
Transcranial electrical stimulation (tES) is a non-invasive form of brain stimulation that has previously been to shown to have therapeutic potential in traumatic brain injury (TBI) patients.
- Trial name
- NCT04239274
- Testing
- transcranial direct current stimulation, transcranial pulsed current stimulation
- Sponsor
- Medical University of South Carolina
Stroke
Combining Transcranial Direct Current Stimulation and Core Stability Exercise on Trunk in Stroke Patient
To evaluate the effects of the combining transcranial direct current stimulation with core stability exercises on trunk performance in poststroke hemiparetic patients, the secondary outcome is to evaluate the balance and the…
- Trial name
- TCDC (NCT06882213)
- Testing
- transcranial direct current stimulation, core stability exercise.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Lumbar Radiculopathy
Comparison of the Efficacy of rTMS and tDCS of the Motor Cortex in Patients With Chronic Neuropathic Pain
The present study aims to compare directly the efficacy of two noninvasive neurostimulation techniques : repetitive transcranial magnetic stimulation and transcranial direct electrical current of the motor cortex in patients with…
- Trial name
- NCT02030626
- Where
- 2 sites in France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Hospital Ambroise Paré Paris
Stroke, Motor Function
Effects of rTMS and tDCS on Motor Function in Stroke
In this study the investigators aim to investigate the effects of two different types of non-invasive brain stimulation techniques -- repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation…
- Trial name
- NCT01574989
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Postural Balance
Effects of Transcranial Direct Current Stimulation on Balance of Children With Balance Deficit
Neural control of posture depends on interaction of sensory and motor information from multiple structures, including the primary motor cortex (M1).
- Trial name
- NCT04341220
- Testing
- Transcranial direct current stimulation (tDCS), Balance exercises
- Where
- Brazil
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Aphasia
Using Transcranial Direct Current Stimulation (tDCS) to Improve Post-Stroke Aphasia
This study tests whether weak electrical stimulation of the brain is effective in improving language or reading difficulties occurring after a brain injury or stroke.
- Trial name
- NCT01709383
- Testing
- Transcranial Direct Current Stimulation
- Where
- 2 sites in United States
- Volunteers
- 38 people
- Sponsor
- Georgetown University
Stroke, Subacute Stroke
Effect of Transcranial Direct Current Stimulation and Pelvic Proprioceptive Neuromuscular Facilitation in Stroke Patient
Stroke is a leading cause of long-term disability and commonly results in impaired trunk control, postural instability, balance deficits, and reduced functional mobility due to disrupted sensorimotor integration, impaired…
- Trial name
- NCT07808580
- Testing
- Pelvic PNF and Transcranial Direct Current Stimulation and Routine Physical Therapy, Pelvic Proprioceptive Neuromuscular Facilitation and Routine Physical Therapy, Transcranial Direct Current Stimulation and Routine Physical Therapy
- Where
- Pakistan
- Volunteers
- 36 people
- Sponsor
- Lahore University of Biological and Applied Sciences
Osteoarthritis, Knee, Chronic Pain
Effect of Cranial Stimulation and Acupuncture on Pain, Functional Capability and Cerebral Function in Osteoarthritis
The objective of this study is to evaluate the efficacy of transcranial direct current stimulation (tDCS) and electro acupuncture (EAC) compared to sham treatment in reducing pain, improving functional capacity and functioning of…
- Trial name
- NCT01747070
- Testing
- tDCS and EAC
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stroke
Single Session of Anodal Cerebellar vs Cerebral Transcranial Direct Current Stimulation in Stroke Patients
To compare the effect of anodal cerebellar transcranial direct current stimulation (ctDCS) vs anodal cerebral direct current stimulation on balance, mobility and cognition in stroke patients in stroke patients
- Trial name
- NCT05129683
- Testing
- Anodal tDCS cerebellar stimulation group, Anodal tDCS cerebral (M1) stimulation group
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Amblyopia
Clinical Treatment of Transcranial Direct Current Stimulation in Older Adolescents With Amblyopia
As a neurodevelopmental visual disorder, amblyopia, especially monocular form-deprivation amblyopia, can lead to severe visual developmental impairments.
- Trial name
- NCT06760910
- Testing
- tDCS Stimulation, Anodal tDCS
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Epilepsy
Electrical Neuromodulation for Focal Epilepsy
The purpose of this research is to use electrical neuromodulation on patients with focal epilepsy. The main objective is to assess safety and observe potential therapeutic effects.
- Trial name
- NCT05844696
- Testing
- Soterix MXN-5 HD-tES Model 5005A. Medtronic Percept DBS platform.
- Volunteers
- 65 people
- Sponsor
- National Taiwan University Hospital
Depression - Major Depressive Disorder
EEG Prediction and Clinical Efficacy of tDCS in Major Depression
The purpose of this randomized controlled trial is to investigate the non-inferiority, and possible superiority, of a high-dose home-based tDCS protocol compared with a conventional home-based protocol, and to assess its…
- Trial name
- DM-TDCS-PREDIC (NCT07611773)
- Testing
- High-dose home-tDCS, Conventional home-tDCS
- Where
- Spain
- Volunteers
- 270 people
- Sponsor
- Ionclinics & Deionic SL
Mild Cognitive Impairment
Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment
Individuals aged 55 and older may experience negative effects of cognitive decline. The proposed research seeks to evaluate the benefits of different types of interventions: reasoning training following transcranial direct…
- Trial name
- NCT02596906
- Testing
- tDCS
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Mild Cognitive Impairment, Sleep
Home Sleep Therapy for Older Adults With MCI
The goal of this clinical trial is to learn about the ability of non-invasive brain stimulation during sleep to enhance people's deep sleep and its potential benefit on memory in people with mild cognitive impairment via home use…
- Conditions
- Mild Cognitive Impairment, Sleep, Transcranial Electrical Stimulation, Machine Learning
- Trial name
- NCT05771844
- Testing
- Transcranial Electrical Stimulation
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Brain Electrophysiology Laboratory Company
Anodal Stimulation tDCS, Major Depression
Effects of tDCS on Cognitive Control and Emotion Regulation in Depressed Patients
Deficient cognitive control (CC) and the use of dysfunctional emotion regulation strategies (ERS) are both central characteristics of major depression.
- Conditions
- Anodal Stimulation tDCS, Major Depression, Cognitive Control, Emotion Regulation
- Trial name
- NCT03039387
- Testing
- anodal transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Cerebral Palsy
Integrated Management Enhances Functional Gains in Children With Cerebral Palsy Treated by BoNT-A
Evidence from literature support the use of Botulinum toxin A (BoNT-A) for upper limb spasticity management in children with cerebral palsy (CP).
- Trial name
- NCT03302871
- Testing
- Botulinum toxin type A, transcranial direct current stimulation, hybrid training model of CIMT and BIT
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kocaeli University
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