Clinical trials: Transcranial Direct Current Stimulation
Primary Progressive Aphasia, PPA
Rehabilitating and Decelerating Language Loss in Primary Progressive Aphasia With tDCS Plus Language Therapy
People with Primary Progressive Aphasia (PPA) are is a debilitating disorder characterized by the gradual loss of language functioning, even though cognitive functioning is relatively well preserved until the advanced stages of…
- Trial name
- NCT03728582
- Testing
- Active tDCS plus Speech-Language Therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Johns Hopkins University
Aphasia Following Cerebral Infarction
Application of Cerebellar tDCS in Aphasia
The goal of this clinical trial is to learn if adding brain stimulation (cerebellar anodal tDCS) helps a computer-based therapy improve word-finding in Cantonese-speaking adults with aphasia after stroke.
- Trial name
- NCT07353879
- Testing
- anodal right posterolateral cerebellar high-definition tDCS, computerized visual speech perception naming intervention
- Where
- 2 sites in Hong Kong
- Volunteers
- 6 people
- Sponsor
- The University of Hong Kong
Stroke, Hemiparesis
Optimizing Transcranial Direct Current Stimulation for Motor Recovery From Severe Post-stroke Hemiparesis
Individuals who experienced a stroke over one year ago will be randomly assigned to receive 1 of 4 different conditions of brain stimulation. All individuals will receive therapy of the hand and arm following the stimulation.
- Trial name
- NCT04574973
- Testing
- transcranial direct current stimulation, intensive upper extremity motor training
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Kentucky
Transcranial Direct Current Stimulation, Autistic Spectrum Disorder
Cumulative and Booster Effects of Multisession Prefrontal tDCS in ASD Adolescents
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by disturbances in communication, poor social skills, and aberrant behavior.
- Conditions
- Transcranial Direct Current Stimulation, Autistic Spectrum Disorder, Electroencephalography
- Trial name
- NCT06272669
- Testing
- Active-tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Motor Learning
TMS-based Assessment of Mental Training Effects on Motor Learning in Healthy Participants
The general purpose of this research project is to analyze the specific role of motor imagery on motor learning, assessed through corticospinal excitability measurements and behavioral data collection.
- Trial name
- IMAP-TMS (NCT04784832)
- Testing
- Transcranial magnetic stimulation, Peripheral Nerve Stimulation, Transcranial direct current stimulation
- Where
- France
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Stress Response
Investigating Stress-Induced Dopamine Release: a fMRI-PET Study
The stress response is mediated by the activation of the hypothalamo-pituitary-adrenal axis and the sympathetic nervous system, leading to glucocorticoid and catecholamines release respectively.
- Trial name
- ISIDORE (NCT05825677)
- Testing
- tDCS actif
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Fibromyalgia
Effect of tDCS in Intrinsic Functional Brain Connectivity Assessed by Functional Magnetic Resonance in Fibromyalgia
Considering the central component of fibromyalgia (FM), the focus of research on current therapeutic approaches has been techniques that may modify the dysfunctional neuroplasticity process, such as transcranial direct current…
- Trial name
- NCT03841227
- Testing
- Active-tDCS
- Where
- 2 sites in Brazil
- Volunteers
- 20 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Epilepsy
Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epilepsy
This project aims to conduct a pilot study based on the targeting of the epileptogenic zone previously localized very precisely by stereoelectroencephalography (SEEG). SEEG is used as part of the pre-surgical assessment.
- Trial name
- GALVANI PS-1 (NCT04782869)
- Testing
- transcranial direct current stimulation
- Where
- France
- Volunteers
- 17 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Acute Stroke
tDCS in Acute Stroke Patients
Very early after the onset of the focal perfusion deficit, excitotoxic mechanisms can lethally damage neurons and glia. Excitotoxicity triggers a number of events that can further contribute to tissue death.
- Trial name
- tDCS (NCT02806856)
- Testing
- tDCS neuroConn
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier St Anne
Balance
Transcranial Direct Current Stimulation and Balance
Postural control is an adaptive sensorimotor process involving continuous integration of sensory information from three channels. These; visual, somatosensory (proprioceptive) and vestibular senses.
- Trial name
- tDCS (NCT06383039)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Zeynep Soy
Prediabetes, Obesity
The Effect of Hypocaloric Diet Associated With tDCS on Weight Loss and Metabolic Profile
To compare four weeks of transcranial direct current stimulation (tDCS) versus placebo associated with a reduced caloric diet on weight loss, glycemic control and regulators of hunger and satiety in overweight or obese subjects…
- Conditions
- Prediabetes, Obesity, Weight Loss, Diabetes
- Trial name
- NCT02683902
- Testing
- Active tDCS, Hypocaloric diet
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Orofacial Pain
Effects of Transcranial Direct Current Stimulation (tDCS) on Patients With Chronic Orofacial Pain
Patients affected by chronic orofacial pain represent an emergent medical problem due to the lack of knowledge on the cause, pathophysiology and psychology of many of these conditions, that belongs to a multifactorial origin.
- Trial name
- NCT01883245
- Testing
- real tDCS
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital of Ferrara
Alcohol Use Disorder (AUD), Alcohol Abuse
Neurobiological Effects of Transcranial Direct Current Stimulation Treatment in Alcohol Use Disorder
Background: Alcohol Use Disorder (AUD) is a complex psychiatric disorder, involving several brain areas and neurocircuits. Transcranial Direct Current Stimulation (tDCS) allows to stimulate superficial areas of brain using a weak…
- Conditions
- Alcohol Use Disorder (AUD), Alcohol Abuse, Alcohol Dependence, Alcohol-Related Disorders
- Trial name
- NCT04897295
- Testing
- Active transcranial Direct Current Stimulation
- Volunteers
- 30 people
- Sponsor
- ITAB - Institute for Advanced Biomedical Technologies
Coronavirus, Inspiratory Muscle Training
Association of Inspiratory Muscle Training With HD-tDCS for Assistance to Patients With Long Covid-19
COVID-19 is an infectious disease which presents a heterogenous clinical presentation. Recent investigations suggest that people who were infected by COVID-19 often develop physical disabilities (i.e.
- Conditions
- Coronavirus, Inspiratory Muscle Training, Respiratory Infection, COVID-19
- Trial name
- NCT05359770
- Testing
- Active HD-tDCS, Control group
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Suellen Marinho Andrade
Stroke, Stroke, Ischemic
tDCS for Neurological Disability Among Subacute Stroke Survivors to Improve Multiple Domains in Quality of Life
Background: tDCS is an emerging noninvasive brain stimulation that triggers neuroplastic changes in the brain. To enhance motor and executive function, tDCS modifies neuronal activity.
- Trial name
- NCT06110169
- Testing
- Anodal Transcranial Direct Current Stimulation (Anodal tDCS)
- Where
- Saudi Arabia
- Volunteers
- 64 people
- Sponsor
- Karthick Balasubramanian
Cognitive Impairment, Cognitive Decline
Neuromodulation Effects in Older Adults
The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compared to cognitively healthy…
- Trial name
- NCT06665022
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Stroke, Upper Extremity Paresis
Cortical Enhancement of Posture, Movement Planning, and Execution of Upright Reaching Following Stroke
Stroke is the leading cause of disability and diminished quality of living that frequently includes impairments of postural control and upper extremity (UE) function.
- Trial name
- NCT04308629
- Testing
- Transcranial direct current stimulation
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Acrophobia, Transcranial Direct Current Stimulation
Efficacy of tDCS to Enhance Virtual Reality Exposure Therapy Response in Acrophobia
The goal of this clinical trial is to examine whether transcranial direct current stimulation(tDCS) can enhance the effect of virtual reality exposure therapy(VRET) in acrophobia in college students with significant fear of…
- Trial name
- NCT05841329
- Testing
- tDCS, virtual reality exposure therapy
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Major Depressive Disorder
Transcranial Direct Current Stimulation (tDCS) in Young Individuals with Major Depressive Disorder: a Literature Review and Feasibility Study
Objectives: (1) To assess the therapeutic effects of tDCS on improving depressive symptoms in young individuals with Major Depressive Disorder (MDD), relative to sham stimulation ; and (2) to evaluate the tolerability, and…
- Trial name
- NCT06518642
- Testing
- Sooma tDCS portable device - active stimulation
- Where
- Hong Kong
- Volunteers
- 8 people
- Sponsor
- The University of Hong Kong
Multiple Sclerosis
Pilot Study of Transcranial Direct Current Stimulation (tDCS)
This study will test the tolerability and preliminary efficacy of transcranial direct current stimulation (tDCS) combined with a cognitive training program, remotely-delivered using a telemedicine protocol in 60 adults with…
- Trial name
- NCT02746705
- Testing
- Transcranial Direct Current Stimulation (tDCS), Cognitive Training Program
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- NYU Langone Health
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