Clinical trials: Transcranial Direct Current Stimulation
Amnestic Mild Cognitive Impairment, Traumatic Brain Injury
Noninvasive Brain Stimulation on Memory in Individuals With Mild Cognitive Impairment and History of Brain Injury
The study will examine the efficacy of high definition transcranial direct current stimulation (HD-tDCS) and its influence on episodic memory in patients with amnestic mild cognitive impairment and a history of Traumatic brain…
- Conditions
- Amnestic Mild Cognitive Impairment, Traumatic Brain Injury, Mild Traumatic Brain Injury
- Trial name
- NCT04504630
- Testing
- High Definition Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Texas Southwestern Medical Center
Neuropathic Pain
Effects of Bodily Illusion and tDCS on SCI-related Neuropathic Pain
The purpose of this study is to evaluate the effect of a combination of two procedures: (1) Bodily Illusion (BI) and (2) Transcranial direct electrical stimulation (tDCS) on neuropathic pain.
- Trial name
- NCT04578574
- Testing
- Bodily Illusions (BI) Procedure, Transcranial direct electrical stimulation (tDCS)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Miami
Pain Management
BreEStim and tDCS for Neuropathic Pain Management - Healthy Subjects
This study looks at the effect of combined breathing-controlled electrical stimulation (BreEStim) and transcranial direct current stimulation (tDCS) on neuropathic pain after spinal cord injury, amputation, or brain injury.
- Trial name
- NCT03302780
- Testing
- BreEStim, tDCS active
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Migraine Disorders
A Study of Home-Delivered Neurostimulation for Migraine
There is a need for better preventive and abortive therapies for migraine. Previous research has indicated that non-invasive neurostimulation may have prophylactic effects on migraine and improve symptoms and functional outcomes…
- Trial name
- NCT03874351
- Testing
- non-invasive transcranial direct current stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 22 people
- Sponsor
- MJHS Institute for Innovation in Palliative Care
Lewy Body Disease, Lewy Body Variant of Alzheimer Disease
Stimulation of Cingulo-opercular Alertness Network
Fluctuations in alertness are very common in persons with Lewy body dementias and are a major source of disability. Changes in a chemical messenger molecule called acetylcholine within certain brain regions may play a role in…
- Conditions
- Lewy Body Disease, Lewy Body Variant of Alzheimer Disease, Lewy Body Dementia With Behavioral Disturbance
- Trial name
- SCAN (NCT04817891)
- Testing
- HD-tDCS
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Major Depressive Disorder
Home-based tDCS in Major Depressive Disorder
The investigators propose a study of telehealth supervised, caregiver-delivered, home-based transcranial direct current stimulation (tDCS) for antidepressant treatment of patients with an acute depressive episode.
- Trial name
- MoodStim (NCT04799405)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Hebrew SeniorLife
Impulsive Behavior
Modulating Impulsivity in Suicidal Adolescents With Transcranial Direct Current Stimulation (tDCS)
As a first step toward investigating whether modulation of impulsivity and associated neural pathways may yield clinically meaningful changes in risk for adolescent suicidal behavior, the R21 is a proof-of concept study…
- Trial name
- tDCS (NCT03365102)
- Testing
- anodal tDCS over the rIFG,, anodal tDCS over the lOFC,
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Lifespan
Parkinson Disease
Parkinson's Disease: Enhancing Physical Therapy With Brain Stimulation for Treating Postural Instability.
This trial aims to understand the mechanism and to test whether transcranial direct current stimulation (tDCS) combined with transcranial ultrasound (TUS) (tDCS+TUS) combined with physical therapy (PT) will induce significant…
- Trial name
- NCT03981055
- Testing
- Active Comparator: Active tDCS and Active TUS, Physical Therapy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Spaulding Rehabilitation Hospital
Schizophrenia, Schizo Affective Disorder
Brain Stimulation and Cognitive Training - Efficacy
People with serious mental illness often experience difficulties with thinking skills like memory. These difficulties can make it harder to perform day-to-day activities.
- Conditions
- Schizophrenia, Schizo Affective Disorder, Bipolar Disorder
- Trial name
- NCT05111548
- Testing
- tDCS (Active), BrainHQ, tDCS (Inactive)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Michigan
Acute Lymphoblastic Leukemia
Treatment for Executive Dysfunction in Adult Survivors of Childhood Acute Lymphoblastic Leukemia
A common and potentially debilitating late effect of childhood cancer treatment is neurocognitive impairment, frequently in the domain of executive dysfunction, which can limit educational attainment, employment, and quality of…
- Trial name
- NCT02336282
- Testing
- transcranial Direct Current Stimulation (tDCS), Cognitive Assessment, Brain Games Stimulation
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- St. Jude Children's Research Hospital
Craving
The Effectiveness of Transcranial Direct Current Stimulation (tDCS) in Decreasing Food Cravings
This study aims to evaluate the effectiveness of transcranial direct current stimulation (tDCS) in decreasing food cravings. Specifically, this study will determine whether healthy subjects will report decreased food craving…
- Trial name
- NCT01030289
- Testing
- real tDCS
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Chronic Low Back Pain
tDCS for Chronic Low Back Pain
The goal of this study is to investigate the role of central neural pathways in mediating chronic pain. The aim of the study is to test the effect of stimulating brain regions that are part of a network underlying central pain…
- Trial name
- NCT02771990
- Testing
- transcranial direct current stimulation
- Volunteers
- 30 people
- Sponsor
- Providence VA Medical Center
Schizophrenia
The Effects of tDCS on the Neuronal Mechanisms of Cognitive Control in Schizophrenia
The purpose of this study is to better understand the neural correlates of cognitive control (CC) deficits in schizophrenia and determine how these mechanisms can be modulated by transcranial direct current stimulation (tDCS).
- Trial name
- NCT03077347
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Fibromyalgia
Optimized tDCS for Fibromyalgia: Targeting the Endogenous Pain Control System
This trial aims at understanding the mechanisms of optimized transcranial direct current stimulation (tDCS) (16 tDCS sessions combined with exercise)] on pain control.
- Trial name
- NCT03371225
- Testing
- Active tDCS, Active Exercise
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Spaulding Rehabilitation Hospital
Status Epilepticus
SURESTEP: Transcranial Direct Current Stimulation in Super Refractory Status Epilepticus
The purpose of this study is to determine whether transcranial direct current stimulation affects super refractory status epilepticus.
- Trial name
- SURESTEP (NCT03819543)
- Testing
- Transcranial Direct Current Stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Mild Cognitive Impairment, Primary Progressive Aphasia
Home-based tDCS in Frontotemporal Dementia or Alzheimer's Disease
The primary objective of this research is to evaluate the effects of non-invasive brain stimulation and computerized cognitive training on executive functioning in individuals with Primary Progressive Aphasia (PPA), mild…
- Conditions
- Mild Cognitive Impairment, Primary Progressive Aphasia, Dementia
- Trial name
- NCT05978804
- Testing
- Computerized Cognitive Training, Active tDCS (tDCS) on DLPFC
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Johns Hopkins University
Aging
Optimizing tDCS to Improve Dual Task Gait and Balance
The objective of this study is to determine the acute effects of single sessions of optimized tDCS, conventional tDCS, and sham stimulation on dual task standing and walking in older adults who are free of overt disease yet who…
- Trial name
- OptiStim (NCT04295798)
- Testing
- Conventional tDCS, Optimized tDCS
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Hebrew SeniorLife
Osteo Arthritis Knee
Self-Administered Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis
The purpose of this study is to assess the feasibility, acceptability, and efficacy of self-administered transcranial direct current stimulation (tDCS) in older adults with knee osteoarthritis (OA)
- Trial name
- NCT04016272
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 123 people
- Sponsor
- Florida State University
Motor Activity, Motor Neuroplasticity
Modulation of Motor Cortex Excitability by TMS and tDCS (MAGS1)
Investigating modulation of motor cortex excitability by transcranial magnetic stimulation and transcranial direct current stimulation.
- Trial name
- NCT03481309
- Testing
- anodal tDCS, cathodal tDCS
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Mild Cognitive Impairment
Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment
Individuals aged 55 and older may experience negative effects of cognitive decline. The proposed research seeks to evaluate the benefits of different types of interventions: reasoning training following transcranial direct…
- Trial name
- NCT02596906
- Testing
- tDCS
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas