Clinical trials: Transcranial Direct Current Stimulation, open to volunteers
Cardiac Surgery
Non-pharmacologial, Non-invassive Intervention Before Cardiac Surgery: a Randomized Controlled Trial
Perioperative neurological complications in cardiovascular surgical procedures are associated with a significant risk of mortality and disability.
- Trial name
- NICE (NCT06791551)
- Testing
- active RIPC and tDCS
- Where
- China
- Volunteers
- 200 people
- Sponsor
- China National Center for Cardiovascular Diseases
Stroke, Cortical Excitability
Dual-task Training Combined With tDCS on Cognitive-motor Performance and Brain Activity in Stroke Patients
This study aims to evaluate the effects of tDCS combined with cognitive-motor training on dual-task interference during walking and foot pedaling, alongside corresponding alterations in brain activity assessed via fNIRS.
- Trial name
- dual-task tDCS (NCT06769672)
- Testing
- active tDCS with dual-task training
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The Hong Kong Polytechnic University
Cannabis Use Disorder
Applying Neuromodulation to Boost the Efficacy of Motivational Interviewing
The goal of this clinical trial is to learn how adding brain stimulation to a brief counseling session affects adults with cannabis use disorder.
- Trial name
- NCT07787572
- Testing
- transcranial alternating current stimulation, Motivational interviewing (MI)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- The Mind Research Network
Schizophrenia
Overnight Thalamic TES-TI to Modulate Sleep Spindles in Individuals With Schizophrenia Spectrum Disorders and Matched Healthy Controls
This study to find out whether a type of non-invasive electrical brain stimulation called transcranial electrical stimulation with temporal interference (TES-TI) can temporarily change brain activity during sleep-especially sleep…
- Trial name
- ONSETS (NCT07680114)
- Testing
- TES-TI
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Insomnia Chronic, Narcolepsy
The Impact of Light, Electrical, and Magnetic Neuroregulation Interventions on Sleep-wake Disorders
Carry out precise and effective neuromodulation interventions, and develop new neuromodulation technologies for sleep disorders.
- Conditions
- Insomnia Chronic, Narcolepsy, REM Sleep Behavior Disorder
- Trial name
- NCT06797284
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Schizophrenia, Cognitive Functions
The Effect of Combined Brain Stimulation and Exercise for Improving Cognitive Function in Schizophrenia
The study will investigate the (1) additive and synergistic effects of tDCS and aerobic exercise on cognitive function and clinical symptoms in schizophrenia, and (2) neurophysiological mechanisms (mediators) underlying these…
- Trial name
- NCT07745140
- Testing
- Aerobic exercise, Active tDCS
- Where
- Hong Kong
- Volunteers
- 66 people
- Sponsor
- The Hong Kong Polytechnic University
Major Depressive Disorder
Accelerated Treatment of Depressive Patients With tDCS
A randomized, controlled three-arm study is planned to investigate the effectiveness and feasibility of an accelerated home-based tDCS application (3 weeks of transcranial direct current stimulation at home, twice daily).
- Trial name
- AcctDCS (NCT07444242)
- Testing
- Transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University of Regensburg
Stroke
Determine the Effect of Targeted High-definition Transcranial Direct Current Stimulation (tDCS) on Reducing Post-stroke Upper Limb Motor Impairments
Significant motor impairments occur in 80% of individuals after moderate to severe stroke and impact the body side to the lesioned hemisphere.
- Trial name
- NCT05479006
- Testing
- Transcranial direct current stimulation (high- definition)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Carle Foundation Hospital
Refractory Status Epilepticus
Application of tDCS Stimulation in Controlling Refractory Status Epilepticus
The purpose of the study is to assess the efficacy and safety of targeting tDCS stimulation for treatment of Refractory status epilepticus
- Trial name
- tDCS (NCT06344338)
- Testing
- tDCS stimulation
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Xuanwu Hospital, Beijing
Fibromyalgia, Psychological Trauma
Augmentation of EMDR With tDCS in the Treatment of Fibromyalgia
Fibromyalgia (FM) is a generalized, widespread chronic pain disorder and has an estimated prevalence of 2%-4% in the general population.
- Conditions
- Fibromyalgia, Psychological Trauma, Depressive Symptoms, Anxiety
- Trial name
- NCT04084795
- Testing
- Eye Movement Desensitization and Reprocessing therapy, transcranial Direct Current Stimulation
- Where
- Spain
- Volunteers
- 96 people
- Sponsor
- Parc de Salut Mar
Post Traumatic Stress Disorder
Noninvasive Brain Stimulation Combined With Written Exposure Therapy for PTSD in Military Personnel With TBI
In this study, the investigators are evaluating whether transcranial direct current stimulation (tDCS), a brain stimulation technique, can be combined with Written Exposure Therapy (WET), a standard talk therapy for posttraumatic…
- Trial name
- NCT07715799
- Testing
- Transcranial Direct Current Stimulator, Written Exposure Therapy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
Tinnitus, Acute
In This Study, we Are Testing Whether Combining Two Interventions, in the Early Stages of Tinnitus, is More Effective in Quieting Tinnitus Than Using One Treatment Alone in the Later Stages of Tinnitus
Tinnitus affects one in seven adults long-term Once present persistently for 4 weeks, tinnitus does not usually disappear People generally become less aware of, and less affected by, their tinnitus over time Only one in six…
- Trial name
- ATtDCS (NCT07128004)
- Testing
- tDCS, sound therapy
- Volunteers
- 80 people
- Sponsor
- Newcastle University
Acute Ischemic Stroke
Transcranial Direct Current Stimulation for Treatment of Acute Ischemic Stroke
Many patients with acute ischemic stroke are ineligible for currently available standard treatments (clot-busting medication, also known as intravenous thrombolytic or mechanical removal of a clot), and many are non-responders…
- Trial name
- TESSERACT 2 (NCT06440707)
- Testing
- High-definition Cathodal Transcranial Direct Current Stimulation (HD C-tDCS)
- Where
- 3 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Stroke, Chronic Stroke
Personalized Transcranial Direct Current Stimulation in Stroke Recovery
The central objective of this application is to explore the neural substrate of personalized tDCS (ptDCS) and to determine whether the paradigm for each stroke patient can predict the amount of sustained clinical improvement…
- Conditions
- Stroke, Chronic Stroke, Hemorrhage Brain, Ischemic Stroke
- Trial name
- NCT06286800
- Testing
- Transcranial direct current stimulation (tDCS) with OT
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The Methodist Hospital Research Institute
Adolescent, Bipolar Depression
HD-tDCS for Adolescent Bipolar Depression Targeting S1
This randomized, double-blind, sham-controlled clinical trial aims to evaluate the efficacy and underlying biological mechanisms of HD-tDCS targeting the primary somatosensory cortex in adolescents with bipolar depression.
- Conditions
- Adolescent, Bipolar Depression, tDCS, Primary Somatosensory Cortex
- Trial name
- NCT07246044
- Testing
- Active HD-tDCS, Antipsychotics, mood stabilizers, etc.
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiangsu Province Nanjing Brain Hospital
Cerebral Palsy (CP), Chronic Pain
Concurrent tDCS for Chronic Pain in Adults With Cerebral Palsy
The purpose of this study is to find out whether combining transcranial direct current stimulation (tDCS) using the Starstim tES8 device with motor-based activities, such as action observation or motor imagery (chosen based on…
- Trial name
- Neuropoint (NCT07846436)
- Testing
- Trans Cranial Direct Current Stimulation
- Volunteers
- 20 people
- Sponsor
- Gillette Children's Specialty Healthcare
Electricity; Effects
HD-tDCS to Modulate Connectivity
The purpose of the proposed study is to broaden our understanding on the neural effects of High Definition Transcranial Direct Current Stimulation (HD-tDCS) so that its clinical effects can be further improved.
- Trial name
- NCT05959551
- Testing
- high definition transcranial direct current stimulation (HD-tDCS)
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Dementia; Degenerative, Dementia Mixed
Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
This research investigates the effect of different frequencies of tACS (0 Hz, 30 Hz, 50 Hz, 70 Hz, 90 Hz) and tRNS with cognitive exercises in a regimen protocol of 4 weeks, everyday (Monday to Friday).
- Trial name
- tES (NCT06877312)
- Testing
- Transcranial Direct Current Stimulation (tDCS), 30 Hz Transcranial Alternating Current Stimulation (tACS), 50 Hz Transcranial Alternating Current Stimulation (tACS)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Autism Spectrum Disorder
Cerebellar tDCS in Children With Autism Spectrum Disorder
The purpose of this research study is to investigate whether tDCS to the cerebellum (specifically, the right crus I/II area of the cerebellum) of children and young adults with autism spectrum disorders (ASD) is safe and to…
- Trial name
- NCT04446442
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Cognitive Impairment, Cognitive Decline
A Mechanistic Study to Investigate tDCS and Working Memory in MCI Patients
The current study is a mechanistic study to evaluate working memory gains from application of transcranial direct current stimulation (tDCS) in older adults with mild cognitive impairments (MCI) compared to cognitively healthy…
- Trial name
- AIM (NCT05998031)
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Florida