Clinical trials: Transcranial Magnetic Stimulation
Treatment Resistant Depression
Dutch-Depression Outcome Trial Comparing 5 Day Multi Daily Neuronavigated Theta Burst Sessions With 6 Weeks rTMS
INTRODUCTION Recent findings from three small studies (total n=59) suggest that three changes in repetitive Transcranial Magnetic Stimulation (rTMS) protocols, called the Stanford Neuromodulation Therapy (SNT) protocol…
- Trial name
- DDOTT (NCT05900271)
- Testing
- rTMS, iTBS
- Where
- 4 sites in Netherlands
- Volunteers
- 108 people
- Sponsor
- Amsterdam UMC, location VUmc
Cervical Dystonia
Plasticity in Cervical Dystonia
This study will identify changes that occur in the part of the brain that controls hand movements in patients with cervical (neck) dystonia.
- Trial name
- NCT00323765
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Unipolar Depression
Title: Safety and Feasibility of Individualized Low Amplitude Seizure Therapy (iLAST)
Background: Electroconvulsive therapy (ECT) is used to treat people with severe depression. During ECT, the brain is given electric pulses that cause a seizure.
- Trial name
- NCT03895658
- Testing
- MRI, MagPro TMS stimulator and coil, Thymatron (R) System IV paired with 4X1 HDECT
- Where
- United States
- Sponsor
- National Institute of Mental Health (NIMH)
Amyotrophic Lateral Sclerosis
Repetitive Transcranial Magnetic Stimulation as Therapy for Depression in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive loss of central and peripheral motor neurons. ALS leads to death usually within 3 to 5 years from the onset of the symptoms.
- Trial name
- NCT03892863
- Testing
- active repetitive transcranial magnetic stimulation
- Where
- Poland
- Sponsor
- Jagiellonian University
Chronic Migraine, Medication Overuse Headache
Non-Invasive Brain Stimulation as Add-on Treatment in Chronic Migraine With Medication Overuse
This randomized, double-blind, sham-controlled clinical trial aims to evaluate the efficacy of non-invasive brain stimulation as an add-on treatment to standard detoxification therapy in patients with chronic migraine and…
- Trial name
- NCT07442916
- Testing
- Active rTMS Motor Cortex Face, Active rTMS - Motor Cortex Forearm
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Depressive Episode, Posttraumatic Stress Disorder
Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation
The purpose of this study is to determine whether transcranial magnetic stimulation (TMS) is effective in the treatment of suicidal thinking in individuals with a depressive episode and either posttraumatic stress disorder…
- Conditions
- Depressive Episode, Posttraumatic Stress Disorder, Traumatic Brain Injury
- Trial name
- NCT01212848
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Obsessive-Compulsive Disorder
Accelerated Rotational Field Deep TMS for Treating OCD
A Prospective Double Blind Randomized Controlled Trial to Evaluate the Efficacy and Durability of the BrainsWay Rotational Field Deep Transcranial Magnetic Stimulation (Deep TMS) in Obsessive-Compulsive Subjects
- Trial name
- NCT07116785
- Testing
- BrainsWay Deep TMS HAC/H7-Coil
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Ben-Gurion University of the Negev
Suicidal Ideation, Suicide, Attempted
iTBS+D-Cycloserine for Youth Suicide
Background and Rationale: Suicide is the second leading cause of death in Canadian Emerging Adults (EAs; 18-24yrs). Current treatments for suicidal thoughts and behaviors are limited and novel treatments are required to save…
- Conditions
- Suicidal Ideation, Suicide, Attempted, Depression, Anxiety
- Trial name
- NCT06121284
- Testing
- D-Cycloserine, intermittent Theta-Burst-repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- University of Calgary
Carcinoma, Non-Small-Cell Lung, Sleep Wake Disorders
Low-Frequency rTMS for In-Hospital Sleep Disturbance in Advanced NSCLC
This randomized, double-blind, sham-controlled trial will evaluate whether low-frequency repetitive transcranial magnetic stimulation (rTMS) can improve in-hospital sleep quality in adults with advanced non-small cell lung cancer…
- Trial name
- NCT07796438
- Testing
- Active Low-Frequency Repetitive Transcranial Magnetic Stimulation
- Volunteers
- 160 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Schizophrenia, Functional Magnetic Resonance Imaging
Effect of Intermittent Theta Burst Stimulation (iTBS) for Alleviating Symptoms of Schizophrenia Patients
To investigate the treatment effect of intermittent theta-burst transcranial magnetic stimulation on symptomatic relief of schizophrenia patients, and the underlying neural mechanism by functional MRI and the resting…
- Conditions
- Schizophrenia, Functional Magnetic Resonance Imaging, Transcranial Magnetic Stimulation
- Trial name
- NCT03868358
- Testing
- transcranial magnetic stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- WANG KAI
Major Depression
Individual Narratives of Stimulation (ECT and TMS)
Electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) are two evidence-based treatments for major depressive disorder.
- Trial name
- INSight (NCT07807930)
- Testing
- There is no intervention in this observation study (qualitative interviews about past treatment experiences)
- Where
- 2 sites in United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Nottingham
Malignancy
Does Transcranial Magnetic Stimulation of the Cingulate Cortex Modulate the Perception of Dyspnoea?
The treatment we are studying is Transcranial Magnetic Stimulation (TMS). In TMS, an electromagnetic pulse is passed into the brain through a coil placed on the head.
- Trial name
- TMS (NCT00830921)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Oxford
Depressive Symptoms, Mild Traumatic Brain Injury
rTMS for Military TBI-related Depression
The purpose of this study is to investigate the efficacy, safety, and tolerability of two dorsolateral prefrontal cortex (DLPFC) repetitive transcranial magnetic stimulation (rTMS) protocols to alleviate symptoms of depression in…
- Conditions
- Depressive Symptoms, Mild Traumatic Brain Injury, Concussion
- Trial name
- ADEPT (NCT05426967)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- 3 sites in United States
- Volunteers
- 198 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Visual Snow Syndrome, Color Blindness
Study of Visual Perception Phenomena: Phosphene Mapping Induced by TMS and Its Relationship With Eye Movements
The purpose of this basic science study is to better understand human visual perception. Phosphenes are flashes of light that can be induced using Transcranial Magnetic Stimulation (TMS).
- Conditions
- Visual Snow Syndrome, Color Blindness, Healthy Volunteer
- Trial name
- NCT07110493
- Testing
- Transcranial Magnetic Stimulation (TMS), Electroencephalography (EEG), Eye-Tracking
- Where
- Russia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Skolkovo Institute of Science and Technology
Chronic Migraine
rTMS for the Prevention Treatment of CM: a Single Arm Study
We design this pilot, single arm study to explore the safety and efficacy of repetitive transcranial magnetic stimulation (rTMS) for the treatment of chronic migraine.
- Trial name
- NCT03568617
- Testing
- rTMS
- Volunteers
- 15 people
- Sponsor
- Peking Union Medical College Hospital
TBI (Traumatic Brain Injury)
Improving Functions in MTBI Patients With Headache by rTMS
Due to recent wars in Afghanistan and Iraq, the number of Veteran suffering from Mild traumatic brain(MTBI) injury and PTSD increases rapidly.
- Trial name
- NCT01948947
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Multiple Sclerosis, Depression - Major Depressive Disorder
Transcranial Magnetic Stimulation for Depression in Multiple Sclerosis
Canada has one of the highest rates of multiple sclerosis (MS). MS patients experience disabling motor, visual, and sensory symptoms, and a high risk of comorbid major depressive disorder (MDD) and severe fatigue.
- Conditions
- Multiple Sclerosis, Depression - Major Depressive Disorder, Fatigue
- Trial name
- NCT07562074
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Alcohol Abuse
Deep Repetitive Transcranial Magnetic Stimulation for Alcohol Use Disorder
dTMS intervention to reduce recurrent alcohol abuse among alcohol users who are abstinent for at least 5 days.
- Trial name
- NCT02691390
- Testing
- Active dTMS
- Volunteers
- 51 people
- Sponsor
- Soroka University Medical Center
Clinical High Risk for Psychosis (CHR), Psychotic Disorders
Accelerated Neuromodulation Therapy and Neurocomputational Biomarkers in Individuals at Clinical High Risk for Psychosis
The goal of this study is to learn whether an accelerated form of neuromodulation therapy is safe, feasible, and well tolerated in young people at clinical high risk for psychosis (CHR-P), and whether it is associated with…
- Conditions
- Clinical High Risk for Psychosis (CHR), Psychotic Disorders, Prodromal Symptoms
- Trial name
- TMS-CHR (NCT07786714)
- Testing
- Active Intermittent Theta Burst Stimulation (BEAM-F3 Targeting)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Douglas Mental Health University Institute
Bipolar Disorder (BD), Cognitive Impairment
TMS for Improving Cognitive Function in Bipolar Disorder
Bipolar disorder is a highly disabling psychiatric illness, and cognitive impairment is common in patients with bipolar depression as well as during remission, contributing substantially to functional disability and poorer…
- Trial name
- NCT07414147
- Testing
- Active Intermittent Theta Burst Stimulation, Online Cognitive Training
- Where
- China
- Volunteers
- 88 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
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