Clinical trials: Transcranial Magnetic Stimulation, completed
Treatment Resistant Disorders
rTMS Effect on Cognitive and Psychiatric Dysfunction in Patients With Fibromyalgia
the aim of this work was to evaluate the effect of low frequency rTMS over the right dorsolateral prefrontal area (DLPFC) on Fibromyalgia patients.
- Trial name
- rTMS (NCT06356805)
- Testing
- repetitive transcranial magnetic stimulation
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Assiut University
OCD
Does TMS Affect Neuroplasticity? The Role of Brain-derived Neurotrophic Factor and Neuronal Cell Adhesion Molecules - an Intensive Clinical Protocol Among Patients With Obsessive-compulsive Disorders
Patients expressing interest in participating will undergo psychiatric assessment to verify the diagnosis of treatment-resistant obsessive-compulsive disorder (OCD), assess symptom severity, and exclude TMS contraindications.
- Trial name
- NCT06231095
- Testing
- continuous theta burst stimulation - cTBS
- Where
- 2 sites in Poland
- Volunteers
- 40 people
- Sponsor
- Wroclaw Medical University
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Brain Plus Spinal Stimulation for Cervical SCI
The goal of this project is to strengthen residual corticospinal tract (CST) connections after partial injury using combined motor cortex and spinal cord stimulation to improve arm and hand function after spinal cord injury…
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Tetraplegia/Tetraparesis
- Trial name
- NCT04727866
- Testing
- transcutaneous spinal direct current stimulation (tsDCS) - coronal, transcutaneous spinal direct current stimulation (tsDCS) - caudal, transcutaneous spinal direct current stimulation (tsDCS) - rostral
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Major Depression
Long-term Bilateral Theta Burst Stimulation for the Treatment of Major Depression
Repetitive transcranial magnetic stimulation has been shown to be moderately effective in the treatment of major depression. Theta burst stimulation (TBS) is a new form of rTMS that may exert larger effects.
- Trial name
- TheBuS_D (NCT01153139)
- Testing
- Repetitive Transcranial Magnetic Stimulation (Theta Burst Stimulation, TBS)
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- University Hospital Tuebingen
Stroke, Muscle Spasticity
Assessment and Management of Post-Stroke Spasticity With Botulinum Toxin-A
Within the first year after stroke, approximately 38% of stroke survivors experience an increased resistance to movement, also called spasticity.
- Trial name
- NCT01751373
- Testing
- Optimal muscle activation therapy, Standard Therapy
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Sunnybrook Health Sciences Centre
Spinal Cord Injuries
Association Between tDCS and Lokomat Training in Patients With Incomplete Spinal Cord Injury
The spinal cord injury is identified as the major cause of permanent disability worldwide, with the loss of ability to walk being the largest and most devastating of them for these patients.
- Trial name
- NCT02562001
- Testing
- Outpatient active group, Inpatient active group
- Where
- Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo General Hospital
Smoking, Addiction
Theta Burst TMS as a Tool to Change Smoking Behavior
The goal of this study is to determine whether transcranial magnetic stimulation (TMS) is an effective treatment in decreasing craving in individuals who habitually smoke cigarettes.
- Trial name
- NCT02939339
- Testing
- continuous theta burst stimulation (real)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical University of South Carolina
Cocaine Use Disorder, Methamphetamine Abuse
rTMS for Stimulant Use Disorders
The purpose of the study is to determine feasibility of repetitive transcranial magnetic stimulation (rTMS) for individuals with moderate to severe cocaine or methamphetamine use disorder (CUD/MUD).
- Conditions
- Cocaine Use Disorder, Methamphetamine Abuse, Cocaine Dependence, Methamphetamine Dependence
- Trial name
- CTN-0108 (NCT04907357)
- Testing
- rTMS
- Where
- 4 sites in United States
- Volunteers
- 129 people
- Sponsor
- Medical University of South Carolina
Cannabis Use Disorder
Investigating Two rTMS Strategies to Treat Cannabis Use Disorder
In this trial we will work with a group of participants who are having problems related to marijuana use (they have Cannabis Use Disorder) and who want to reduce the amount of marijuana they use or quit using marijuana…
- Trial name
- NCT05720312
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Stanford University
Healthy
Effect of Transcranial Magnetic Stimulation on Free Will
This study will use transcranial magnetic stimulation (TMS) to investigate how the brain controls movement by sending messages to the spinal cord and muscles.
- Trial name
- NCT00029653
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Depression, Anxiety
Symptom-specific TMS Targets for Depression and Anxiety
This pilot study aims to compare two different treatment targets for transcranial magnetic stimulation, an FDA-approved treatment for major depressive disorder (MDD), in terms of their relative efficacy for depression versus…
- Conditions
- Depression, Anxiety, Major Depressive Disorder
- Trial name
- NCT04604210
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Major Depressive Disorder, Bipolar Depression
The Study of Effectiveness of rTMS on Rumination and Anhedonia in Patients With Major Depressive Disorder
Rumination is significantly frequent in major depressive disorder. However, not a lot of studies have investigated the effects of repetitive transcranial magnetic stimulation on rumination and its electrophysiological correlates.
- Trial name
- NCT03468686
- Testing
- Bilateral rTMS, Unilateral rTMS (High frequency)
- Where
- Iran
- Volunteers
- 61 people
- Sponsor
- University of Tehran
Stroke
The Immediate Effects of Intermittent Theta Burst Stimulation on Intracortical Excitability of the Primary Motor Cortex in Patients With Chronic Stroke
This study is to investigate the immediate effects of intermittent theta burst stimulation (iTBS) on intracortical excitatory and inhibitory circuits, neural connectivity, and network properties in patients with chronic stroke…
- Trial name
- NCT05509686
- Testing
- Intermittent theta burst stimulation (iTBS)
- Where
- Hong Kong
- Volunteers
- 21 people
- Sponsor
- The Hong Kong Polytechnic University
Smoking Cessation
Enhancing Relapse Prevention for Smoking Cessation With Repetitive Transcranial Magnetic Stimulation
Tobacco use is one of the most significant cancer control and public health challenges in the US today. Half of all smokers in the US will attempt to quit tobacco each year, but fully 95% of those who attempt to quit will reverse…
- Trial name
- rTMS (NCT02822703)
- Testing
- rTMS Active 20Hz
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- The City College of New York
Headache
eNeura SpringTMS Post-Market Observational US Study of Migraine
A multi-center, prospective, non-randomized, single arm, open label, post-market, observational study to evaluate the use of the eneura, springtms system in reduction of migraine headache symptoms.
- Trial name
- ESPOUSE (NCT02357381)
- Testing
- eNeura SpringTMS
- Where
- 7 sites in United States
- Volunteers
- 263 people
- Sponsor
- eNeura, Inc.
Complex Regional Pain Syndrome (CRPS)
Transcranial Magnetic Stimulation (TMS) for CRPS
The purpose of this pilot study is to test the durability of response to Transcranial Magnetic Stimulation (TMS) for the symptoms of Complex Regional Pain Syndrome (CRPS).
- Trial name
- NCT02067273
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Methamphetamine Abuse
Transcranial Magnetic Stimulation for Methadone Maintenance Therapy Combined With Methamphetamine Abuse
Repetitive transcranial magnetic stimulation (rTMS) has been used to treat opioid and methamphetamine addiction in previous studies, while no evidence was proved for patients methadone maintenance therapy with methamphetamine…
- Trial name
- NCT04264741
- Testing
- repetitive transcranial magnetic stimulation (rTMS)
- Where
- China
- Volunteers
- 55 people
- Sponsor
- Shanghai Mental Health Center
Motor Function of Healthy Physiology
Modulation of Motor Function by Stimulation of the Central and Peripheral Nervous System
Objectives When a stroke damages the part of the brain that controls movement, people have weakness and difficulty using their hand.
- Trial name
- NCT00453505
- Testing
- TMS, tDCS, tACS
- Where
- United States
- Volunteers
- 976 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stress Disorders, Post-Traumatic, Brain Injuries
Pathophysiological Understanding and Treatment of PTSD: an rTMS Approach
In Canada, the prevalence of PTSD is approximately 12%, similar to Canadian military personnel. Current treatments for PTSD are limited in efficacy and durability - indicating a dire need for novel interventions in this…
- Conditions
- Stress Disorders, Post-Traumatic, Brain Injuries, Transcranial Magnetic Stimulation, Magnetic Resonance Spectroscopy
- Trial name
- PTSD (NCT03840369)
- Testing
- Repetitive Transcranial Magnetic Stimulation to Right Dorsolateral Prefrontal Cortex, Repetitive Transcranial Magnetic Stimulation to Right Dorsomedial Prefrontal Cortex
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Calgary
Alzheimer's Disease
Deep Transcranial Magnetic Stimulation for Treatment of Alzheimer's Disease
The primary objective of this trial is to assess the ability of Transcranial Magnetic Stimulation with H coil to prefrontal cortex , with an addition of cognitive brain training, to improve cognitive performance in patients with…
- Trial name
- NCT01179373
- Testing
- TMS, H coil
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Brainsway
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