Clinical trials: Transcranial Magnetic Stimulation
Autism Spectrum Disorder, Catatonia
Use of MRI and cTBS for Catatonia in Autism
Despite the significant morbidity and mortality associated with catatonia in autism, no diagnostic research has attempted to identify biomarkers for catatonia.
- Conditions
- Autism Spectrum Disorder, Catatonia, Intellectual Disability
- Trial name
- NCT06016764
- Testing
- Continuous Theta Burst in Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Vanderbilt University Medical Center
Subthreshold Depression, Positive Emotions
The Effect of Transcranial Direct Current Stimulation (tDCS) in Improving Emotion Health
The goal of this clinical trial is to investigate how transcranial direct current stimulation (tDCS) affects emotion functions in young adults aged 18-35 from the local community, including both male and female participants.
- Conditions
- Subthreshold Depression, Positive Emotions, Negative Emotions, Anhedonia
- Trial name
- NCT07319143
- Testing
- Transcranial Direct Current Stimulation
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
PARKINSON DISEASE (Disorder)
The Effect of rTMS Over the SMA on Gait Performance in Parkinson's Disease
This study aims to investigate the effects of high-frequency and low-frequency repetitive transcranial magnetic stimulation (rTMS) over the supplementary motor area (SMA) on gait performance, especially gait initiation, in…
- Trial name
- NCT07190235
- Testing
- Transcranial Magnetic Stimulation
- Where
- Hong Kong
- Volunteers
- 81 people
- Sponsor
- The Hong Kong Polytechnic University
Schizophrenia, Depression
Magnetic Stimulation of the Brain in Schizophrenia or Depression
The primary objective is to evaluate if repetitive transcranial magnetic stimulation (rTMS) with theta burst frequency over dorsomedial prefrontal cortex (DMPFC) is an effective treatment for negative symptoms (anhedonia and…
- Conditions
- Schizophrenia, Depression, Anhedonia, Avolition
- Trial name
- MA-SCH-DEP (NCT02905604)
- Testing
- dmPFC iTBS
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Uppsala University
Nicotine Dependence
Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction
Background: Treatment for nicotine addiction is characterized by high rates of relapse. New treatment therapies for nicotine addiction are exploring the use of brain scanning equipment to control and decrease nicotine and…
- Trial name
- NCT01031693
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
COVID-19 Vaccine Adverse Reaction
Detoxification From the Lipid Tract
Apart from electroencephalogram biofeedback and electrical brain stimulation adopted for maintenance treatment, the study utilizes ultra-low frequency transcranial magnetic stimulation (ULF-TMS) for initial γ-aminobutyric acid…
- Trial name
- NCT06357104
- Testing
- electroencephalogram biofeedback, electrical brain stimulation, ultra-low frequency transcranial magnetic stimulation
- Where
- China
- Volunteers
- 1 people
- Sponsor
- Pachankis, Yang I., M.D.
Depression
The Antidepressant Efficacy of Low Frequency rTMS as add-on
rTMS has appeared a potential new non-invasive antidepressant method, which implies non-convulsive focal stimulation of the brain through a time varying magnetic field. ).
- Trial name
- NCT02966106
- Testing
- Right prefrontal low frequency rTMS
- Sponsor
- University of Aarhus
Movement Disorder, Healthy
Study of Brain Control of Movement
This study will use transcranial magnetic stimulation to examine how the brain controls movement by sending messages to the spinal cord and muscles and what goes wrong with this process in disease.
- Trial name
- NCT00017979
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Apraxia Speech
Transcranial Magnetic Stimulation (TMS) for Primary Progressive Apraxia of Speech (PPAOS)
The purpose of this study is to assess the influence of transcranial magnetic stimulation (TMS) on speech performance in individuals with primary progressive apraxia of speech.
- Trial name
- NCT03028324
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Miami
Nemaline Myopathy Type 6, Myotonic Dystrophy Type 2
Muscle Relaxation in Myopathies With Positive Muscle Phenomena
The aim of this study is to quantify muscle relaxation properties of the finger flexor muscles in patients with different myopathies.
- Conditions
- Nemaline Myopathy Type 6, Myotonic Dystrophy Type 2, McArdle Disease
- Trial name
- NCT03211923
- Testing
- Transcranial magnetic stimulation (TMS)
- Volunteers
- 30 people
- Sponsor
- Radboud University Medical Center
Depression Minor
Probing Homeostatic Plasticity With Priming Theta-burst Stimulation of the Dorsolateral Prefrontal Cortex
Priming stimulation is a highly promising tool to boost the beneficial effects of therapeutic repetitive transcranial magnetic stimulation (rTMS) in psychiatry.
- Trial name
- NCT04031105
- Testing
- Theta-burst stimulation (TBS)
- Where
- Hong Kong
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dr Georg Kranz
Substance Use Disorders, Methamphetamine Use Disorders
Individualized Neuromodulation of Craving Control for Meth Use Disorders
Drug craving is one of the key aspects of substance use disorders (SUDs) and is associated with continued drug use and relapse. Approximately 70% of those entering treatment will relapse within one year.
- Trial name
- NCT06695637
- Testing
- active cTBS
- Sponsor
- University of Minnesota
Amyotrophic Lateral Sclerosis
Cervical Electrical Stimulation for ALS
Veterans are at higher risk than non-Veterans of falling ill with amyotrophic lateral sclerosis (ALS). ALS causes degeneration of motor neurons in both the brain and the spinal cord.
- Trial name
- NCT03411863
- Testing
- CES at rest, CES plus active hand or wrist movements
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Parkinson Disease, Epilepsy
In Vivo Imaging of Therapeutic Electric Current Flow
The purpose of this research study is to measure current flow inside the head using magnetic resonance imaging (MRI). The data from this study will be used to map the current flow caused from the electrical stimulation inside the…
- Conditions
- Parkinson Disease, Epilepsy, Alzheimer's Disease, Stroke
- Trial name
- tDCS (NCT02453763)
- Testing
- Transcranial direct current stimulation, MRI
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Florida
Peripheral Neuropathy
Analgesic Effect of Accelerated Repetitive Transcranial Magnetic Stimulation in Neuropathic Pain
Peripheral neuropathy is a frequent condition, commonly associated with pain. Repetitive Transcranial Magnetic Stimulation (rTMS) is a noninvasive method of modulation of brain plasticity and is regarded as one of alternative…
- Trial name
- NCT05295498
- Testing
- Active repetitive transcranial magnetic stimulation
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Jakub Antczak
Suicidal Ideation
Precision Phenotyping of Behavioral Risk and Response to Electromagnetic and Psychedelic Therapies
PRE-EMPT will assemble a study group of 150 civilian and Veteran participants from three populations (low risk, intermediate risk, and high risk for self-harm).
- Trial name
- PRE-EMPT (NCT07484906)
- Testing
- fMRI Neurofeedback, Accelerated theta burst stimulation, Psilocybin assisted therapy
- Sponsor
- University of New Mexico
Binge-Eating Disorder
Theta Burst Stimulation in Binge Eating Disorder: A Single Session RCT
Binge eating disorder (BED) is a common and disabling eating disorder (ED) which presents a substantial disease burden. Individuals seeking treatment for binge eating difficulties typically receive talking therapy treatment…
- Trial name
- BITE (NCT04130906)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- United Kingdom
- Sponsor
- King's College London
Spinal Cord Injuries
Neural Facilitation of Movements in People With SCI
Spinal cord injury leads to long-lasting paralysis and impairment. Re-enabling movement of paralyzed areas is challenging and more information is needed about neurological recovery.
- Trial name
- NCT05354206
- Testing
- Electrophysiology assessment - corticospinal tract, Electrophysiology assessment - reticulospinal tract, Training with some stimulation
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Spinal Cord Injuries, Neuralgia
Long-term Effects of Repetitive TMS in Chronic Neuropathic Pain in People With SCI
Around 80% of people with spinal cord injury (SCI) develop chronic neuropathic pain (CNP). This is a debilitating condition with major negative impacts on people's quality of life.
- Conditions
- Spinal Cord Injuries, Neuralgia, Chronic Pain
- Trial name
- NCT05226676
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Primary Progressive Nonfluent Aphasia
Transcranial Magnetic Stimulation in Nonfluent/Agrammatic Variant Primary Progressive Aphasia
Nonfluent/agrammatic variant primary progressive aphasia (nf/avPPA) is a fatal neurodegenerative disease that begins with isolated language deficits. There is currently no cure or treatment for this disease.
- Trial name
- NCT03153540
- Testing
- Active iTBS
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of British Columbia
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