Clinical trials: Transcranial Magnetic Stimulation
Major Depressive Disorder
Treatment of Major Depressive Disorder With Bilateral Theta Burst Stimulation
This is a randomized, double-blind, sham-controlled multicenter clinical trial. The aim is to provide evidence for efficacy of TBS in the treatment of patients with major depression.
- Trial name
- TBS-D (NCT04392947)
- Testing
- Transcranial Magnetic Stimulation
- Where
- 7 sites in Germany
- Volunteers
- 238 people
- Sponsor
- University Hospital Tuebingen
Major Depressive Disorder, Suicide
Accelerated iTBS for Depression and Suicidality
The overall objective of this current study is to evaluate the feasibility, safety, and tolerability of "high dose" aiTBS in psychiatric inpatient and outpatients with treatment-refractory unipolar, non-psychotic major depressive…
- Trial name
- RAPID (NCT04441008)
- Testing
- Accelerated Intermittent Theta Burst (aiTBS), Electroconvulsive therapy (ECT)
- Volunteers
- 50 people
- Sponsor
- University of Iowa
Gastric Bypass Surgery Pain Management
Transcranial Magnetic Stimulation Effects on Pain Perception
The purpose of this research study is to investigate the effects of Transcranial Magnetic Stimulation on pain perception. TMS is a non - invasive technique that uses electromagnetic pulses to temporarily stimulate specific brain…
- Trial name
- TMS (NCT01861574)
- Testing
- Real TMS 45 min, Real TMS 4 Hours
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Medical University of South Carolina
Transcranial Direct Current Stimulation
Mechanism and Dosimetry Exploration in TES Magnetic Resonance Current Mapping Methods
In this study the investigators will explore dosimetry in transcranial electrical stimulation using a novel magnetic resonance imaging technique that can determine how electrical stimulation distributes within the brain.
- Trial name
- TES (NCT03772210)
- Testing
- tDCS
- Where
- 2 sites in United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Suspected Non-Alzheimer Disease Pathophysiology (SNAP)
Cognitive Effects of Theta-burst Stimulation (TBS) in Suspected Non-Alzheimer Disease Pathophysiology (SNAP)
This is a pilot study to identify a homogeneous cohort of pathologically specific dementia with SNAP for clinical trial of brain stimulation.
- Trial name
- SNAP (NCT05440110)
- Testing
- active and active TBS
- Where
- Taiwan
- Volunteers
- 17 people
- Sponsor
- Chang Gung Memorial Hospital
Major Depressive Disorder
A Double-blind Sham Controlled Trial of rTMS in Treatment Resistant Major Depression
The main treatment option for Treatment Resistant Depression is electroconvulsive therapy (ECT) which is often effective but complicated by cognitive side effects, need for anaesthesia and considerable stigma.
- Trial name
- NCT00402220
- Testing
- TMS
- Where
- Australia
- Volunteers
- 67 people
- Sponsor
- Bayside Health
Autism Spectrum Disorder
Precision TMS Treatment Guided by Personalized Brain Functional Sectors (pBFS) for ASD
This study will evaluate the efficacy and safety of pBFS-guided TMS treatment for the core symptom in autism spectrum disorder children, adolescents and young adults.
- Trial name
- NCT05890846
- Testing
- active iTBS, traditional 1on1 course
- Where
- 2 sites in China
- Volunteers
- 66 people
- Sponsor
- Changping Laboratory
Mild Cognitive Impairment
Gaze and Gait Training With rTMS
The purpose of this study is to evaluate the feasibility of combining repetitive transcranial magnetic stimulation (rTMS), gaze and gait training to improve walking and balance in people with or without mild cognitive impairment.
- Trial name
- NCT05864313
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Gait training, Gaze training
- Volunteers
- 30 people
- Sponsor
- University of Florida
Chronic Pain
Personalized Treatment by rTMS in Chronic Pain - Study2
Previous research has shown the effectiveness of magnetic stimulation of the brain as a supplemental treatment for various conditions, such as depression and chronic pain.
- Trial name
- PersoNINpain (NCT07247552)
- Testing
- rTMS to M1
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Aalborg University
Aphasia, Rehabilitation
Acupuncture + Neuromodulation for Post-Stroke Aphasia
The aim of this clinical trial is to assess the therapeutic efficacy of acupuncture combined with neuromodulation techniques for the treatment of post-stroke aphasia and to explore the brain mechanisms involved.
- Trial name
- NCT06493747
- Testing
- Combined Low- and High-Frequency rTMS Intervention, Combined High- and Low-Frequency rTMS Intervention, rTMS
- Where
- China
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Shanghai Yueyang Integrated Medicine Hospital
Oropharyngeal Dysphagia, Stroke
The Utility of Cerebellar Transcranial Magnetic Stimulation in the Neurorehabilitation of Dysphagia After Stroke
The study is designed to explore the effectiveness of non-invasive cerebellar stimulation to enhance motor plasticity in the cortex after stroke.
- Trial name
- NCT03274947
- Testing
- Cerebellar TMS
- Where
- 2 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Healthy
Brain Use of Sensory Information to Generate Movement
This study will use transcranial magnetic stimulation (TMS) to investigate functions of brain regions that may use information from sensory organs, such as the eyes or ears, to generate movements.
- Trial name
- NCT00055289
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Opioid-use Disorder, Heroin Abuse
Repetitive Transcranial Magnetic Stimulation to Reduce Heroin Cravings
The purpose of this research study is to test the effect of repetitive transcranial magnetic stimulation (rTMS) on opioid cravings among adult patients with Opioid Use Disorder.
- Conditions
- Opioid-use Disorder, Heroin Abuse, Craving, Transcranial Magnetic Stimulation
- Trial name
- NCT05074524
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Nevada, Las Vegas
Opioid-use Disorder, Substance-Related Disorders
An Open-Label Trial of Repetitive Transcranial Magnetic Stimulation for Opioid Use Disorder
The purpose of this study is to understand the role of repetitive Transcranial Magnetic Stimulation (rTMS) in reducing opioid and other substance use and craving and improving thinking skills.
- Conditions
- Opioid-use Disorder, Substance-Related Disorders, Chemically-Induced Disorders, Mental Disorder
- Trial name
- NCT04157062
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Sponsor
- West Virginia University
Inflammatory Bowel Diseases, Maladaptive Behavior Associated With Physical Illness
TMS in Inflammatory Bowel Disease
Transcranial magnetic stimulation (rTMS) has demonstrated diagnostic and therapeutic potential for a number of conditions and is an approved treatment for depression.
- Trial name
- NCT04956159
- Testing
- iTBS repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Calgary
Neuropathic Pain, Depression
Neuromodulation in Patients With Neuropathic Pain and Depression.
High-frequency repetitive transcranial magnetic stimulation of the primary motor cortex has shown its effect on refractory neuropathic pain, and rTMS of the dorsolateral prefrontal cortex is commonly used for treatment-resistant…
- Trial name
- DOLODEP (NCT06129890)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS) - M1/DLPFC, Repetitive transcranial magnetic stimulation (rTMS) - DLPFC/M1
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
PTSD
Transcranial Magnetic Stimulation to Improve Functioning in Veterans With PTSD
Posttraumatic Stress Disorder (PTSD) is a common and serious condition affecting many Veterans. There are effective treatments for PTSD, but additional treatments are needed in order to better serve Veterans suffering from PTSD.
- Trial name
- rTMS for PTSD (NCT04207346)
- Testing
- TMS 1 hz
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- VA Office of Research and Development
Binge-Eating Disorder
Theta Burst Stimulation in Binge Eating Disorder: A Case Series
Binge eating disorder (BED) is a common and disabling eating disorder (ED) which presents a substantial disease burden. Individuals seeking treatment for binge eating difficulties typically receive talking therapy treatment…
- Trial name
- BITE (NCT04129970)
- Testing
- Intermittent Theta Burst Stimulation
- Where
- United Kingdom
- Sponsor
- King's College London
Stroke
Role of Ipsilateral Motor Cortex in Executing Movements With Increasing Demand on Precision
It is well known that the motor area of one hemisphere of the brain (motor cortex) controls the movement of the opposite of the body.
- Trial name
- RIMC (NCT01726218)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cathrin Buetefisch
Auditory Hallucinations in Patients With Schizophrenic Disorders
High Frequency Repetitive Transcranial Magnetic Stimulation (rTMS) in Schizophrenia : a Randomized Controlled Study
Background: Repetitive transcranial magnetic stimulation (rTMS) is a recent therapeutic which has demonstrated its efficacy in the treatment of auditory hallucinations in patients with schizophrenic disorders.
- Trial name
- TMS-Hz (NCT01022489)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 72 people
- Sponsor
- University Hospital, Caen
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