Clinical trials: Transcranial Magnetic Stimulation
Parkinson's Disease
The Cerebellum as a Potential Treatment Site for PD Motor Symptoms
The role of the cerebello-thalamo-cortical loop in the generation of tremor, gait impairments and postural instability has been made evident.
- Trial name
- NCT02387346
- Testing
- Magstim Rapid 2 Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Sun Life Financial Movement Disorders Research and Rehabilitation Centre
Primary Progressive Aphasia, Frontotemporal Dementia
Long-term Effect of TMS in Primary Progressive Aphasia
There are very few treatments for neurodegenerative disorders, and the efficacy of these treatments is generally modest. Recent studies have shown a short-term positive effect of non-invasive neuromodulation techniques such as…
- Conditions
- Primary Progressive Aphasia, Frontotemporal Dementia, Alzheimer Disease
- Trial name
- RECONNECT (NCT05842473)
- Testing
- Transcranial Magnetic Stimulation (active), Language therapy
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Hospital San Carlos, Madrid
Knee Osteoarthritis, Chronic Pain
Neurophysiological Mechanisms Involved in Knee Osteoarthritis
Introduction: Total knee arthroplasty (TKA) is an effective intervention to relieve people with osteoarthritis (OA). Nevertheless, 15 to 30% of patients continue to experience severe pain following surgery.
- Trial name
- NCT03556423
- Where
- 2 sites in Canada
- Volunteers
- 28 people
- Sponsor
- Université de Sherbrooke
Anorexia Nervosa, Bulimia Nervosa
Transcranial Treatments in Eating Disorders
The primary aim of this study is to study how Repetitive Transcranial Magnetic Stimulation (rTMS) tailored to specific anorexia nervosa (AN) or bulimia nervosa (BN) brain activation alterations will promote recovery and to study…
- Trial name
- NCT02535780
- Testing
- Transcranial magnetic stimulation, Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Colorado, Denver
Spinal Cord Injury, Neuropathic Pain
Effect of TMS on Neuropathic Pain for Patients With Spinal Cord Injury
Patients will be randomly assigned to three groups using a randomization scheme: active primary motor cortex (M1) rTMS, active anterior cingulate cortex (ACC) rTMS, or sham M1 rTMS.
- Trial name
- NCT07293780
- Testing
- active rTMS of M1, active rTMS of anterior cingulate cortex
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Ankara Etlik City Hospital
Bipolar Disorder
rTMS for Treatment of Depressed Phase of Bipolar Disorder Type II
This research study evaluates an experimental device for the treatment of the depressed phase of Bipolar Disorder Type II. Repetitive Transcranial Magnetic Stimulation (rTMS) is an experimental procedure where a device delivers…
- Trial name
- rTMS (NCT00447096)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Sponsor
- University of Texas Southwestern Medical Center
Schizophrenia
TMS in Treatment of Schizophrenia Negative Symptoms
Primary objective: to examine the efficacy and safety of high frequency repetitive transcranial magnetic stimulation (HF rTMS) with H7-coil applied once daily during the twenty days, augmentative to the standard antipsychotic…
- Trial name
- NCT04268797
- Testing
- HR rTMS
- Where
- Croatia
- Volunteers
- 104 people
- Sponsor
- Sveti Ivan Psychiatric Hospital
Parkinson Disease, Healthy
Transcranial Magnetic Stimulation in Parkinson's Disease
This study will use transcranial magnetic stimulation (TMS) to explore how the brain controls movement by sending messages to the spinal cord and muscles and what goes wrong with this process in disease.
- Trial name
- NCT00023062
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Depressive Disorder, Major
Does Nurse Semi Structured Interview Added to a rTMS Improve Patients With Major Depressive Disorder?
Repeated Transcranial Magnetic Stimulation - R.TMS - is currently part of the treatment for depressive illness. This non-invasive technique is designed to stimulate certain areas of the cerebral cortex involved in this pathology.
- Trial name
- DESTIMCARE (NCT03436823)
- Testing
- nurse semi-structured interview, Music & Relaxation with eyes closed
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Mild Cognitive Impairment
Transcranial Magnetic Stimulation and Cognitive Stimulation in Mild Cognitive Impairment
This study evaluates the effect of 5Hertz (Hz) repetitive Transcranial Magnetic Stimulation (rTMS) on Left Dorsolateral Prefrontal Cortex enhancing Cognitive Stimulation in Mild Cognitive Impairment.
- Trial name
- rTMS&MCI (NCT03906903)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Cognitive Stimulation
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Universidad Autonoma de Queretaro
Dystonia, Focal Dystonia
Brain Changes in Blepharospasm
This study will examine the role of certain areas of the brain in blepharospasm, a type of dystonia (abnormality of movement and muscle tone) that causes unwanted or uncontrollable blinking or closing of the eyelids.
- Conditions
- Dystonia, Focal Dystonia, Cerebellar Disease
- Trial name
- NCT00487383
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Pilot Study: A Novel Method of Non-Invasive Brain Stimulation (kTMP) to Enhance Motor Function in Chronic Stroke Patients
Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities.
- Trial name
- NCT06317194
- Testing
- kTMP
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Magnetic Tides
Stroke
Repetitive Transcranial Magnetic Stimulation Use in Acute Stroke
When a certain area of the brain is injured, like in stroke, several events occur. One side of the body may become weak. This weakness is called hemiparesis and it may create difficulty in performing tasks like writing, eating…
- Trial name
- NCT01922986
- Testing
- active rTMS, conventional stroke therapy
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Minnesota
Depression
Efficacy of Repetitive Transcranial Magnetic Stimulation in the Prevention of Relapse of Depression
The purpose of this study is to evaluate the efficacy of repetitive transcranial magnetic stimulation in the prevention of relapse of the symptoms of depression.
- Trial name
- NCT01516931
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS), counseling
- Where
- China
- Volunteers
- 391 people
- Sponsor
- Xijing Hospital
Major Depressive Disorder
Study to Evaluate Treatment Effects Associated With the NeuroStar SoftStart Treatment Feature
The purpose of this study is to evaluate the comfort of the NeuroStar® Advanced Therapy System regular prescribed TMS protocol versus a New Feature.
- Trial name
- Comfort Start (NCT05535062)
- Testing
- repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Neuronetics
Dementia With Lewy Bodies Diagnosis, Significant Cognitive Fluctuations in DLB
Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) in Cognitive Fluctuations of Dementia With Lewy Bodies (DLB): Proof of Concept
The present study is a monocentric, therapeutic clinical trial involving forty patients diagnosed with Dementia with Lewy Bodies (DLB).
- Trial name
- STIMLEWY (NCT05138588)
- Testing
- rTMS
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Healthy Volunteers
Safety and Feasibility of St. Mark's Electrode for the Hypoglossal Nerve and Cortico-lingual Pathway Study
The possibility of registering the M-response and the motor evoked potential (MEP) from the muscles of the tongue by using the St. Mark's electrode will be evaluated. The safety of method will be confirmed.
- Trial name
- NCT05070273
- Testing
- Hypoglossal nerve conduction study, Transcranial magnetic stimulation of hypoglossal nerve
- Where
- Russia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of Russia
Writer's Cramp, Healthy Volunteers
Propensity to Develop Plasticity in the Parieto-Motor Networks in Dystonia From the Perspective of Abnormal High-Order Motor Processing
Background: People with dystonia have muscle contractions they can t control. These cause slow, repeated motions or abnormal postures. People with dystonia have abnormalities in certain parts of the brain.
- Conditions
- Writer's Cramp, Healthy Volunteers, Cervical Dystonia
- Trial name
- NCT02504905
- Testing
- TMS
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Major Depressive Disorder Remission, Major Depressive Disorder
Vulnerability Markers for Depression
The current study is a pilot for the GRF project entitled "Predicting illness trajectories in fully remitted major depression using concurrent TBS/fNIRS".
- Conditions
- Major Depressive Disorder Remission, Major Depressive Disorder, Healthy
- Trial name
- NCT06402422
- Testing
- Theta-burst stimulation
- Where
- Hong Kong
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Transcranial Magnetic Stimulation, Freezing of Gait
Effect of Theta-Burst Transcranial Magnetic Stimulation (TBS) for Freezing of Gait
To investigate the treatment effect of Theta-burst Transcranial Magnetic Stimulation (TBS) on patients with freezing of gait (FOG) and the underlying neural mechanism.
- Trial name
- NCT05192759
- Testing
- Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
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