Clinical trials: Transcranial Magnetic Stimulation
Stroke, Spinal Cord Injuries
Cortical Biomarkers of Hand Function and Recovery After Injury
This is a pilot study to collect data to support a VA grant submission to study fMRI and neurophysiological predictors of hand function and recovery during a robotic intervention in people with hand impairments due to stroke or…
- Trial name
- NCT03833518
- Testing
- Rehabilitation using motorized glove for stroke and spinal cord injury, Functional MRI for stroke and spinal cord injury, Transcranial magnetic stimulation (TMS) for stroke and spinal cord injury
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- VA Pittsburgh Healthcare System
Post Stroke Aphasia
Effect of High Frequency Transcranial Magnetic Stimulation on Recovery of Chronic Post-Stroke Aphasia
high frequency excitatory rTMS applied over the dominant hemisphere in chronic post stroke aphasic patients to help the restoration of function by the left hemisphere
- Trial name
- NCT04708197
- Testing
- rTMS (repetitive transcranial magnetic stimulation )
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Stroke
Can rTMS Enhance Somatosensory Recovery After Stroke?
Stroke affects over 795,000 Americans every year and has an enormous impact on the well-being of American Veterans with 6,000 new stroke admissions every year.
- Trial name
- NCT02811913
- Testing
- repetitive transcranial magnetic stimulation (rTMS), peripheral sensory stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Chronic Tinnitus
Conventional Repetitive Transcranial Magnetic Stimulation for Tinnitus Treatment
The objective of the investigators study is to assess conventional repetitive transcranial magnetic stimulation (rTMS) in patients with chronic severe tinnitus.
- Trial name
- MagTIN (NCT01407133)
- Testing
- transcranial magnetic stimulator (class 2b) Medtronic © MagPro X100 (with MagOption) stimulator and Butterfly Coil MCF-B65 (figure-8 coil with fluid cooling)
- Where
- 3 sites in France
- Volunteers
- 64 people
- Sponsor
- Hospices Civils de Lyon
Depressive Disorder
The Effect of Transcranial Direct Current Stimulation on Cognitive Side Effects of Electroconvulsive Therapy
Electroconvulsive therapy (ECT) is an effective treatment for a variety of psychiatric disorders. However, despite continued advances in ECT technique, neurocognitive dysfunction continues to be a frequent adverse effect.
- Trial name
- NCT02897843
- Testing
- transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Northwell Health
PTSD
Rapid Acceleration Process for Intensive Treatment of PTSD in 5 Days
Veterans with posttraumatic stress disorder (PTSD) need more effective treatments. Existing options can have limited adherence and can be very time-consuming. As such, alternative interventions are needed.
- Trial name
- RAPID5 (NCT07167940)
- Testing
- Transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- VA Office of Research and Development
Depression
Cognition and Behavior With Sham Accelerated TMS
The goal of this clinical study is to understand how a person's expectations about treatment can influence their mood, motivation, and reactions to everyday rewards.
- Trial name
- NCT07397858
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, Davis
Epilepsy
Transcranial Magnetic Stimulation for Epilepsy
The goal of the present clinical trial is to determine whether low frequency (0.5 Hz) rTMS can induce long term depression in epileptogenic cortex and thus suppress cortical excitability at the epileptic focus.
- Trial name
- TMS (NCT02757547)
- Testing
- Transcranial magnetic stimulation - Active Arm
- Volunteers
- 2 people
- Sponsor
- Electrical Geodesics, Inc.
Stimulant Dependence, Methamphetamine-dependence
Pilot TMS for Methamphetamine Use Disorder
This is a pilot study to test the feasibility of a recruitment strategy and study protocol to examine the effects of a dual target transcranial magnetic stimulation treatment in methamphetamine use disorder.
- Conditions
- Stimulant Dependence, Methamphetamine-dependence, Addiction, Drug
- Trial name
- NCT04449055
- Testing
- Transcranial Magnetic Stimulation--DPFC first, MPFC second, Transcranial Magnetic Stimulation--MPFC first, DPFC second
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Ryan M. Carnahan
Depression, Major Depressive Disorder
Left vs. Right Non-Inferiority Trial
The aim of this study is to test the hypothesis that low-frequency rTMS (LFR) works as well as the established intermittent thetaburst rTMS (iTBS) treatment for treatment resistant depression (TRD).
- Conditions
- Depression, Major Depressive Disorder, Major Depressive Episode
- Trial name
- LeRNIT (NCT04999553)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Intermittent Theta Burst Stimulation (iTBS), Low Frequency Right (LFR)
- Where
- 2 sites in Canada
- Volunteers
- 480 people
- Sponsor
- University of British Columbia
Tinnitus
The Efficacy of Repetitive Transcranial Magnetic Stimulation in Patients With Chronic Subjective Tinnitus
The aim of this study is to compare the efficacy of frequency-specific patterned repetitive transcranial magnetic stimulation (rTMS) and 1Hz rTMS for the treatment of chronic subjective tinnitus.
- Trial name
- NCT06635967
- Testing
- frequency-specific rTMS, 1 Hz rTMS
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Autism Spectrum Disorder, Major Depressive Disorder
Transcranial Magnetic Stimulation for Depression in Autism Spectrum Conditions
In this research study the investigators aim to learn more about the therapeutic effects of a newer form of non-invasive transcranial magnetic stimulation (TMS), called theta burst simulation (TBS), on refractory depression in…
- Trial name
- RESTORE (NCT05271357)
- Testing
- Bilateral TMS, Unilateral TMS
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
1. Major Depressive Disorder
Supplemental Transcranial Magnetic Stimulation (TMS) vs. Standard Medication Monotherapy for Treating Major Depression: An Exploratory Field Study
A. Introduction to the Problem This field experiment is intended to explore whether supplemental transcranial magnetic stimulation (TMS) is more effective than standard medication mono-therapy for the treatment of major…
- Trial name
- NCT01944657
- Testing
- Supplemental TMS, Standard Medication Monotherapy
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheppard Pratt Health System
Major Depressive Disorder
Algorithm Guided Treatment Strategies for Major Depressive Disorder
The purpose of this study is to compare treatment outcomes between measurement based Algorithm Guided Treatment and Treatment As Usual strategies in a Chinese population with major depressive disorder.
- Trial name
- AGTs-MDD (NCT01764867)
- Testing
- Escitalopram, Mirtazapine, modified electroconvulsive therapy
- Where
- China
- Volunteers
- 1,080 people
- Sponsor
- Shanghai Mental Health Center
Anorexia Nervosa
Theta Burst Stimulation in Anorexia Nervosa
Anorexia Nervosa (AN) is a life-threatening eating disorder characterised by an intense fear of weight gain and disturbed body image, which motivates severe dietary restriction or other weight loss behaviours (e.g. purging).
- Trial name
- ANTS (NCT03984344)
- Testing
- Intermittent Theta Burst Stimulation, Continuous Theta Burst Stimulation
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- King's College London
Depression
Assessing an EEG Biomarker of Response to TMS for Major Depression
Veterans with treatment resistant depression (TRD) have the opportunity to receive transcranial magnetic stimulation (TMS) treatment via the VA's National TMS Clinical Pilot Program.
- Trial name
- NCT05008198
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 266 people
- Sponsor
- VA Office of Research and Development
Healthy
Concurrent TMS and EEG Pilot Study
This study will investigate the test-retest reliability of transcranial magnetic stimulation (TMS) -evoked potentials (TEPs) as measured by electroencephalography (EEG), using three different TMS protocols over five different…
- Trial name
- NCT05665634
- Testing
- Concurrent transcranial magnetic stimulation and electroencephalogram
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Stroke, Upper Extremity Dysfunction
Comparison of the Effects of Mirror Therapy,rTMS and Robotic-assisted Hand Therapy in Stroke Patients
The aim of the study is to investigate the comparison of the effects of mirror therapy, Repetitive Transcranial Magnetic Stimulation and robot-assisted hand therapy added to conventional neurological rehabilitation on upper…
- Conditions
- Stroke, Upper Extremity Dysfunction, Neuropathic Pain, Quality of Life
- Trial name
- NCT06750692
- Testing
- Mirror Therapy, Low-Frequency Repetitive Transcranial Magnetic Stimulation, Robot-Assisted Hand Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Afyonkarahisar Health Sciences University
Non Fluent Aphasia in Subacute Stroke
Dual Hemisphere rTMS for Rehabilitation of Post Stroke Aphasia
To investigate the therapeutic effect of dual hemisphere repetitive transcranial magnetic stimulation (rTMS) on post-stroke non fluent aphasia.
- Trial name
- NCT01850836
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Assiut University
Bipolar Disorder
Effects of Theta Burst Stimulation on the Brain, Behavior, and Clinical Symptoms in Adults With Bipolar Disorder
Bipolar Disorder (BD) is a common and highly debilitating psychiatric disorder, however, the predisposing brain mechanisms are poorly understood.
- Trial name
- NCT04696471
- Testing
- Continuous Theta Burst Stimulation (cTBS)
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Mary Phillips, MD MD (Cantab)
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