Clinical trials: Transcranial Magnetic Stimulation
Schizophrenic Disorders
Interest of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Auditory Hallucinations
Auditory hallucinations are common (present in 60-70% of cases) and extremely debilitating. Behavioral disorders associated with them can have serious social repercussions.
- Trial name
- TMS HALLU (NCT02525315)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
PTSD
Neuromodulation of the Fear Extinction Circuit Using Temporally and Anatomically Specific TMS in Humans
This study aims to explore the mechanisms of how transcranial magnetic stimulation (TMS) impacts fear circuits. The overarching objectives are to understand how varying TMS parameters affect targeted brain regions in order to…
- Trial name
- NCT05368987
- Testing
- Transcranial magnetic stimulation (TMS), Fear Conditioning and Extinction Paradigm
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Treatment Resistant Depression, MDD
Psilocybin rTMS for Treatment Resistant Depression
The purpose of this study is to determine the safety and feasibility of sequencing psilocybin therapy with a short-duration, aiTBS protocol (Stanford Accelerated Intelligent Neuromodulation Therapy, or SAINT) in individuals with…
- Conditions
- Treatment Resistant Depression, MDD, Major Depressive Disorder, Recurrent Depression
- Trial name
- PSILOBSD (NCT06132178)
- Testing
- Psilocybin, Accelerated intermittent theta burst (aiTBS) rTMS treatment, Low-dose psilocybin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Texas at Austin
Depressive Episode, Posttraumatic Stress Disorder
Transcranial Magnetic Stimulation (TMS) for Suicidal Ideation
The purpose of this study is to determine whether transcranial magnetic stimulation (TMS) is effective in the treatment of suicidal thinking in individuals with a depressive episode and either posttraumatic stress disorder…
- Conditions
- Depressive Episode, Posttraumatic Stress Disorder, Traumatic Brain Injury
- Trial name
- NCT01212848
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- INTRuST, Post-Traumatic Stress Disorder - Traumatic Brain Injury Clinical Consortium
Parkinson Disease, Mild Cognitive Impairment
Superior Parietal iTBS for PD-MCI
The goal of this study is to determine the whether a short-term, high-dose form of non-invasive brain stimulation (intermittent theta burst stimulation; iTBS) is a promising and safe treatment for mild cognitive impairment in…
- Trial name
- NCT07701785
- Testing
- Accelerated intermittent theta-burst stimulation (iTBS) rTMS to right superior parietal lobule (rSPL)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Mental Disorders, Schizophrenia
STIM'ZO : Examining tDCS as an add-on Treatment for Persistent Symptoms in Schizophrenia
This project aims to provide the proof of concept for transcranial direct-current stimulation (tDCS) in the treatment of resistant/persistent Schizophrenia symptoms.
- Trial name
- STIM'ZO (NCT02744989)
- Testing
- Neuroconn or Neuroelectric tDCS stimulator
- Where
- 10 sites in France, Monaco
- Volunteers
- 141 people
- Sponsor
- Hospices Civils de Lyon
Cocaine-Related Disorders
Treatment With Transcranial Magnetic Stimulation for Cocaine Addiction: Clinical Response and Functional Connectivity.
The purpose of this study is to investigate the short and long term clinical and cognitive effects of repetitive Transcranial Magnetic Stimulation (rTMS) at 5 Hz and/or 10 Hz frequencies on the left dorsolateral prefrontal cortex…
- Trial name
- TMS_COC_CONN (NCT02986438)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Major Depressive Disorder, Suicide
Accelerated iTBS for Depression and Suicidality
The overall objective of this current study is to evaluate the feasibility, safety, and tolerability of "high dose" aiTBS in psychiatric inpatient and outpatients with treatment-refractory unipolar, non-psychotic major depressive…
- Trial name
- RAPID (NCT04441008)
- Testing
- Accelerated Intermittent Theta Burst (aiTBS), Electroconvulsive therapy (ECT)
- Volunteers
- 50 people
- Sponsor
- University of Iowa
Major Depressive Disorder
A Double-blind Sham Controlled Trial of rTMS in Treatment Resistant Major Depression
The main treatment option for Treatment Resistant Depression is electroconvulsive therapy (ECT) which is often effective but complicated by cognitive side effects, need for anaesthesia and considerable stigma.
- Trial name
- NCT00402220
- Testing
- TMS
- Where
- Australia
- Volunteers
- 67 people
- Sponsor
- Bayside Health
Unipolar Depression, Bipolar Disorder
Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression
Depressed mood is the main symptom of depression, but other symptoms like cognitive impairment, anhedonia or sleep disorders may also contribute to patients suffering and are difficult to treat.
- Trial name
- NCT06363981
- Testing
- Active rTMS over the left DLPFC and over the left DMPFC, Active rTMS over the left DLPFC
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Jakub Antczak
Epilepsy
PHArmacotherapy Assessed Using Neuroprobing With TransOsseal Magnetic Stimulation
The goal of this observational study is to investigate how prescribed anti-seizure medications (ASMs) affect cortical excitability in adults with epilepsy. The main questions it aims to answer are: 1.
- Trial name
- PHANTOMS (NCT06892457)
- Testing
- TMS-EEG
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Parkinson Disease, Idiopathic
Clinical Trail of Transcranial MR-guided Focused Ultrasound in the Treatment of Motor Symptoms in Patients With Parkinson' Disease
Randomized, double-blind, self-cross-over control (After the first visit, patients are divided into two groups, randomly receiving real stimulation/placebo stimulation.
- Trial name
- NCT06639945
- Testing
- transcranial MR-guided focused ultrasound
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Multiple Sclerosis
Repetitive Deep Transcranial Magnetic Stimulation in Multiple Sclerosis
Multiple sclerosis (MS) is a chronic-inflammatory autoimmune central nervous system disorder and a leading cause of neurological disability in younger adults in Western countries.
- Trial name
- rTMS in MS (NCT01106365)
- Testing
- H-coil (Repetitive deep transcranial magnetic stimulation)
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Stroke, Ischemic
Effects of Intermittent Theta Burst Stimulation in Addition to Constraint-Induced Movement Therapy in Stroke Patients
In recent studies, it has been reported that intermittent theta-burst stimulation (iTBS) provides additional benefits when applied in adjunct to the rehabilitation in all stages of stroke (acute, subacute, or chronic).
- Trial name
- NCT05308667
- Testing
- Rehabilitation (modified constraint-induced movement therapy), non-invasive brain stimulation (intermittent theta-burst stimulation)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Istanbul Medeniyet University
Parkinson Disease
Effects of Rhythmic Auditory Cueing on Stepping in Place in Patients With Parkinson's Disease
Patients with Parkinson's disease have internal rhythm dysfunction, which may affect the rhythmic movements such as walking. Poor regularity of the rhythmic movement may lead to freezing of gait.
- Trial name
- NCT03271736
- Testing
- Stepping-in-place exercise with external auditory cues, Transcranial magnetic stimulation (TMS)
- Where
- Taiwan
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- HsiuYun Chang
Healthy Volunteers
Establishing Functional Biomarkers for Spaced Theta-Burst Stimulation
The investigators plan to use functional magnetic resonance imaging (fMRI) methods to assess brain changes following spaced theta burst stimulation (TBS), a new form of repetitive transcranial magnetic stimulation (rTMS), in 10…
- Trial name
- NCT03687892
- Testing
- continuous Theta Burst Stimulation, intermittent Theta Burst Stimulation
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Stanford University
Traumatic Brain Injury
Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials
Patients evaluated at Penn Presbyterian Medical Center for traumatic brain injury (TBI), who sign the informed consent, will undergo assessment of electrophysiologic potentials evoked by transcranial magnetic stimulation (TMS)…
- Trial name
- (TMS-EEG) (NCT06963775)
- Testing
- Delphi-MD device (QuantalX Neuroscience Ltd., Saba Israel)
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- Ramon Diaz-Arrastia
Smoking
Transcranial Magnetic Stimulation in Smokers: an Examination of Mediating Neural Pathways.
The primary objective of this study is to examine the effects of repetitive transcranial magnetic stimulation (rTMS) on a regulation of craving task (ROC task) and evaluate the feasibility of targeting rTMS via fMRI based…
- Trial name
- NCT05651334
- Testing
- Active repetitive Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Kent State University
Small Fiber Neuropathy
Magnetic Brain Stimulation in Small Fiber Neuropathy
Small fiber neuropathy (SFN) is a condition in which the smallest nerve fibers are damaged. This leads to severe pain and disturbances in the body's automatic functions.
- Trial name
- rTMS in SFN (NCT07805057)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Netherlands
- Volunteers
- 124 people
- Sponsor
- Maastricht University Medical Center
Schizophrenia; Psychosis
Efficacy of Maintenance Repetitive Transcranial Magnetic Stimulation (rTMS) in Auditory Verbal Hallucinations
Repetitive transcranial magnetic stimulation (rTMS) can alleviate persistent auditory verbal hallucinations (AVH) in schizophrenic patients, but the classical procedure with low-frequency stimulation for several weeks upon the…
- Trial name
- MAINSTIM (NCT05550155)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Caen
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