Clinical trials: Transcranial Magnetic Stimulation
Obsessive Compulsive Disorder
Transcranial Magnetic Stimulation (TMS) in Obsessive Compulsive Disorder (OCD): Mechanisms and Biomarkers
The purpose of this study is to test the efficacy of 1-Hz repetitive transcranial magnetic stimulation (TMS) over the pre-supplementary motor area as a treatment for obsessive compulsive disorder.
- Trial name
- TMSOCD (NCT02355002)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Massachusetts General Hospital
Stroke, Brain Injuries
Brain Mechanisms Underlying Reading Improvement in Central Alexia
Central alexia is a common reading disorder caused by stroke. Patients with central alexia (CA) are slow to read and make frequent errors, and have additional problems with their spoken language. This study has 3 aims: 1.
- Conditions
- Stroke, Brain Injuries, Aphasia
- Trial name
- NCT02062619
- Testing
- Computer-based behavioural word reading therapy, Real tDCS
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- University College, London
Parkinson's Disease
Repetitive Transcranial Magnetic Stimulation(rTMS) Regulating Slow-wave to Delay the Progression of Parkinson's Disease
At present, no drug therapy has been proven to delay the progression of Parkinson's disease (PD). rTMS, as a non-invasive neuromodulation method, can regulate Slow-wave sleep (SWS).
- Trial name
- NCT06002581
- Testing
- rTMS real stimulation stage1, rTMS real stimulation stage 2
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Focal Dystonia
rTMS and Retraining in Focal Hand Dystonia
This study is exploring a new experimental procedure in dystonia called repetitive transcranial magnetic brain stimulation (TMS) combined with rehabilitation.
- Trial name
- DSS (NCT01738581)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Sensorimotor Retraining, Non-specific Therapy
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of Minnesota
Dementia With Lewy Bodies Diagnosis, Significant Cognitive Fluctuations in DLB
Personalized Repetitive Transcranial Magnetic Stimulation (rTMS) in Cognitive Fluctuations of Dementia With Lewy Bodies (DLB): Proof of Concept
The present study is a monocentric, therapeutic clinical trial involving forty patients diagnosed with Dementia with Lewy Bodies (DLB).
- Trial name
- STIMLEWY (NCT05138588)
- Testing
- rTMS
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Parkinson Disease (PD)
Transcranial Magnetic Stimulation for Freezing of Gait in Parkinson's Disease
This study evaluated transcranial magnetic stimulation (TMS) for freezing of gait in patients with Parkinson's disease. Participants with Parkinson's disease and freezing of gait received conventional TMS protocols, and their…
- Trial name
- PD-FOG-TMS (NCT07731841)
- Testing
- Primary Motor Cortex Transcranial Magnetic Stimulation, Spinal Cord Magnetic Stimulation, SMA TMS
- Where
- China
- Volunteers
- 85 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Metastatic Malignant Neoplasm in the Brain, Radiation Therapy Recipient
nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor Cortex
This trial studies how well nTMS works in planning for stereotactic radiosurgery in patients with brain metastases in the motor cortex.
- Trial name
- NCT04062305
- Testing
- Hand Function Test, Navigated Transcranial Magnetic Stimulation, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- M.D. Anderson Cancer Center
Alcohol Addiction
Transcranial Magnetic Stimulation in the Treatment of Addiction
The investigators hypothesize that repetitive transcranial magnetic stimulation (rTMS) on the right side of the head will make craving towards alcohol less severe in recently detoxified alcohol addicted patients.
- Trial name
- MAGENTA (NCT01973127)
- Testing
- Verum rTMS
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- IrisZorg
Post-Concussion Syndrome, Concussion, Brain
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
The goal of this study is to investigate a new treatment for chronic symptoms after concussion or mild traumatic brain injury in people aged 18-65 years old.
- Conditions
- Post-Concussion Syndrome, Concussion, Brain, Mild Traumatic Brain Injury, Head Injury
- Trial name
- NCT06073886
- Testing
- Active cTBS, Imaginal exposure
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Los Angeles
Affective Disorder
New Techniques for Diagnosis and Treatment of Cognitive Impairment in Affective Disorder
The purpose of this study is to explore the pathological mechanism of cognitive impairment in patients with affective disorder based on brain gut axis research, preliminarily verify the clinical efficacy of new neural regulation…
- Trial name
- NCT05596461
- Testing
- Transcranial magnetic stimulation, Transcranial direct current stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Bradykinesia, Parkinson Disease
prTMS as an Intervention for Bradykinesia in Parkinson's Disease
This study investigates the use of patterned repetitive transcranial magnetic stimulation (prTMS) as an intervention for bradykinesia in Parkinson's Disease (PD).
- Trial name
- ADAPT-BK (NCT07397377)
- Testing
- Active patterned repetitive transcranial magnetic stimulation (prTMS)
- Where
- Denmark
- Volunteers
- 27 people
- Sponsor
- Danish Research Centre for Magnetic Resonance
Healthy
Stability of rTMS on Cognition and Brain Networks on Healthy Subjects.
Episodic and working memory processes are the most affected cognitive domains in Alzheimer's Disease (AD) and its early stage, Mild Cognitive Impairment (MCI).
- Trial name
- NCT01861639
- Testing
- ineffective rTMS, active TBS, fMRI
- Where
- 2 sites in France, Spain
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- Qualissima
Craving, Depression, Anxiety
Repetitive Transcranial Magnetic Stimulation in Amphetamine Addiction
The study aims to test whether transcranial magnetic stimulation (TMS) improves the craving, depression, anxiety and cognitive function during the abstinent period of methamphetamine users.
- Conditions
- Craving, Depression, Anxiety, Amphetamine Addiction
- Trial name
- NCT04993300
- Testing
- transcranial magnetic stimulation (TMS)
- Where
- Taiwan
- Volunteers
- 5 people
- Sponsor
- National Taiwan University Hospital
Overweight and Obesity, Inhibition, Psychological
Inhibitory Control Training and iTBS for Excess Weight: Behavioral and Brain Changes (InhibE).
People with excess weight (EW) are characterized by high impulsivity, high levels of craving for high-calorie foods, deficits in inhibitory control, and maladaptive decision-making.
- Trial name
- InhibE (NCT06668077)
- Testing
- iTBS of the left DLPFC, iTBS of the vertex, Inhibitory control training
- Where
- Spain
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Raquel Vilar López
Generalized Anxiety Disorder
Navigated cTBS for the Treatment of Generalized Anxiety Disorder
The purpose of this study is to investigate the effectiveness of a non-invasive brain stimulation technique called continuous Theta Burst Stimulation (cTBS) for treating Generalized Anxiety Disorder (GAD).
- Trial name
- NAVI-GAD (NCT07121712)
- Testing
- Mapsd Continuous Theta Burst Stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- WANG KAI
Addiction, Opioid
Role of High Frequency RTMS in Management of Opioid Use Disorder
This study aims to evaluate the role of repetitive Transcranial Magnetic Stimulation (rTMS) applied to the left dorsolateral prefrontal cortex (DLPFC) in reducing pain, decreasing craving, alleviating withdrawal symptoms…
- Conditions
- Addiction, Opioid, RTMS
- Trial name
- NCT06689072
- Testing
- rTMS, Psychotherapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Logopenic Progressive Aphasia
Can Magnetic Brain Stimulation Improve Language Function in Primary Progressive Aphasia
The purpose of this study is to investigate the feasibility of using repetitive transcranial magnetic stimulation (rTMS) - a form of non-invasive brain stimulation - to improve language functioning in individuals who have the…
- Trial name
- NCT04193267
- Testing
- MagStim Rapid2 Transcranial Magnetic Simulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Stroke, Hemiparesis After Stroke
Optimizing Cortical Priming
Each year over 795,000 people suffer from stroke resulting in the primary cause of adult disability. Persistent upper limb dysfunction due to stroke significantly impairs performance and results in a serious decline of quality of…
- Trial name
- NCT07860073
- Testing
- 5 Hz Repetitive transcranial magnetic stimulation (rTMS) on the contralesional dorsal premotor cortex (cPMd), 5 Hz Repetitive transcranial magnetic stimulation (rTMS) on the ipsilesional primary motor cortex (iM1)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Wan-Wen Liao
Rotator Cuff Tears
Central Neuromuscular Dysfunction, Functionality, Psychological Status and Rotator Cuff Surgery
Considering the fact that The problems experienced by the patients are not only physiological but also psychological and social. Unfortunately, there is no sufficient study focus on all these concepts.
- Trial name
- NCT05566470
- Testing
- Assessment of Central Neuromuscular Dysfunction, Shoulder Physical Functionality and Psychological Factors
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Borderline Personality Disorder (BPD)
Combining Transcranial Magnetic Stimulation With Emotion Regulation Skills Training in Borderline Personality Disorder
Impaired emotion regulation is a core feature of borderline personality disorder (BPD) and a known driver of functional impairment, interpersonal difficulties, self-harm, and suicidality.
- Trial name
- NCT07714005
- Testing
- Transcranial Magnetic Stimulation (TMS), Emotion Regulation Skills Training
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Massachusetts General Hospital
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