Clinical trials: Transcranial Magnetic Stimulation
Major Depressive Disorder, Depression
Mechanism of Action of Transcranial Magnetic Stimulation
This is an observational neuroimaging study assessing the effects of TMS on the brains of patients with unipolar depression.
- Trial name
- NCT04278521
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Massachusetts General Hospital
Schizophrenia Spectrum Disorder
Transcranial Magnetic Stimulation (TMS) for Negative Symptoms in Schizophrenia Spectrum Disorders
The purpose of this study is to determine if repetitive transcranial magnetic stimulation (rTMS) applied to angular gyrus (AG) will improve negative symptoms and/or other psychosis symptoms in schizophrenia spectrum disorders…
- Trial name
- NCT07290738
- Testing
- TMS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Bipolar Disorder
A Study to Evaluate the Effect of Single Doses of Drug A (Lamotrigine) and Drug B (Vofopitant) Alone and in Combination on Resting Motor Threshold in Healthy Subjects
The purpose of this study is to investigate the effect of drug A on its own and when it is given in combination with drug B on markers of brain activity. The study will 1.
- Trial name
- NCT00907985
- Testing
- Vofopitant, Lamotrigine
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Bipolar Depression
An Open Label Trial of TMS Therapy for Bipolar Depression
Transcranial Magnetic Stimulation (TMS) is an increasingly accepted neurostimulation- based treatment for major depressive disorder.
- Trial name
- NCT02640950
- Testing
- NeuroStar TMS
- Where
- 2 sites in United States
- Volunteers
- 31 people
- Sponsor
- Sheppard Pratt Health System
Depression, Treatment Resistant Depression
Mindfulness Engaged Neurostimulation for Depression (MEND II)
Repetitive Transcranial Magnetic stimulation (rTMS) is an FDA-approved therapy for treatment resistant depression (TRD) that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region.
- Conditions
- Depression, Treatment Resistant Depression, Major Depressive Disorder, Depressive Disorder
- Trial name
- NCT07512284
- Testing
- Medi-TBS
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, San Diego
Spinal Cord Injuries, Spinal Cord Diseases
PAS for Lower Extremity Rehabilitation in Tetraplegic Patients
The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles…
- Trial name
- NCT03459885
- Testing
- Paired associative stimulation (with eXimia magnetic stimulator and Dantec Keypoint® electroneuromyography device)
- Where
- Finland
- Volunteers
- 5 people
- Sponsor
- Helsinki University Central Hospital
Parkinson's Disease, Mild Cognitive Impairment
Effect of Transcranial Magnetic Stimulation on Cognition and Neural Changes in Parkinson's Disease
Parkinson's disease (PD) affects more than 100,000 Canadians and results in symptoms affecting both motor and cognitive (thinking and memory) functions.
- Trial name
- PD-MCI-TMS (NCT03243214)
- Testing
- TMS
- Where
- Canada
- Volunteers
- 41 people
- Sponsor
- University of Calgary
Spinal Cord Injuries, Spinal Cord Diseases
PAS in Subacute SCI
The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles.
- Trial name
- NCT04101916
- Testing
- Paired associative stimulation
- Where
- Finland
- Volunteers
- 18 people
- Sponsor
- Helsinki University Central Hospital
Internet Gaming Disorder
The Effect of Repetitive Transcranial Magnetic Stimulation for Internet Gaming Disorder
This study aims to investigate the intervention effects of navigated repetitive transcranial magnetic stimulation (rTMS) on craving regulation in individuals with internet gaming disorder (IGD).
- Trial name
- NCT06634498
- Testing
- real rTMS on the dlPFC
- Where
- 2 sites in China
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Jin-tao Zhang
Schizophrenic Disorders
Interest of Repetitive Transcranial Magnetic Stimulation (rTMS) in the Treatment of Auditory Hallucinations
Auditory hallucinations are common (present in 60-70% of cases) and extremely debilitating. Behavioral disorders associated with them can have serious social repercussions.
- Trial name
- TMS HALLU (NCT02525315)
- Testing
- Transcranial magnetic stimulation: rTMS
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Caen
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
EEG and TMS-based Biomarkers of ALS, MS and FTD
The purpose of this observational study is to improve understanding of the biology of why ALS, MS and FTD have different effects on different people and facilitate better measurement of the disease in future drug testing.
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Multiple Sclerosis
- Trial name
- NCT04918251
- Testing
- 128 electrode electroencephalography (EEG), Transcranial magnetic stimulation (TMS)
- Where
- Ireland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Dublin, Trinity College
Anorexia Nervosa
Transcranial Magnetic Stimulation (TMS) in the Treatment of Anorexia Nervosa
Anorexia nervosa is a severe psychiatric disorder associated with food avoidance and body image distortion, that is feeling fat despite being underweight.
- Trial name
- NCT05368844
- Testing
- rTMS treatment using BrainsWay Model 104 system with H1-Coil
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, San Diego
Essential Tremor
Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor
The purpose of this study is to evaluate the efficacy and electrophysiology of repetitive transcranial magnetic stimulation in the treatment of essential tremor.
- Trial name
- rTMS (NCT06145932)
- Testing
- real rTMS
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Major Depressive Disorder
NeuroStar TMS Therapy System: Utilization and Outcomes
The major objective of this observational study is to describe clinical outcomes of patients receiving treatment with the NeuroStar TMS Therapy system in routine clinical practice.
- Trial name
- NCT01114477
- Where
- 44 sites in United States
- Volunteers
- 307 people
- Sponsor
- Neuronetics
Glioblastoma
TMS Electrochemotherapy for Glioblastoma Multiforme
The proposed project aims to develop novel electrochemotherapeutic treatment of glioblastoma multiforme (GBM). Standard treatment has limited effect on survival and quality of life.
- Trial name
- NCT02283944
- Testing
- TMS
- Sponsor
- University of Aarhus
Cerebrovascular Stroke
Noninvasive Brain Stimulation to Evaluate Neural Plasticity After Stroke
The purpose of this study is to examine how different areas in the brain interact with each other and how using brain imaging and brain stimulation approaches can influence these interactions.
- Trial name
- NCT02465034
- Testing
- Transcranial Magnetic Stimulation, Traditional Paired Associative Stimulation, Median Nerve Stimulation
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Emory University
Unipolar Depression, Bipolar Disorder
Multisite rTMS for Mood, Cognitive Impairment and Other Symptoms of Depression
Depressed mood is the main symptom of depression, but other symptoms like cognitive impairment, anhedonia or sleep disorders may also contribute to patients suffering and are difficult to treat.
- Trial name
- NCT06363981
- Testing
- Active rTMS over the left DLPFC and over the left DMPFC, Active rTMS over the left DLPFC
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Jakub Antczak
Somatic Symptom Disorder
Use Repetitive Transcranial Magnetic Stimulation to Treat Somatic Symptom Disorder
This is a randomized double-blind sham-controlled crossover study; the interventions are high-frequency rTMS stimulation on left DLPFC and sham control. The study population is the patient with somatic symptom disorder.
- Trial name
- NCT05161819
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Transcranial Magnetic Stimulation, Parkinson Disease
TMS Treatment in Parkinson's Disease With Pain.
Transcranial magnetic stimulation (TMS) is a procedure that has been shown to improve pain in chronic sufferers. It is a well-tolerated procedure that can be performed on an outpatient basis.
- Conditions
- Transcranial Magnetic Stimulation, Parkinson Disease, Pain
- Trial name
- TMSPDP (NCT04048265)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- China
- Volunteers
- 52 people
- Sponsor
- Xuanwu Hospital, Beijing
Depression, Depressive Disorder
Stimulation of Parieto-hippocampal Connectivity in Patients With Major Depressive Disorder
This study aims to investigate the effects of individualized repetitive transcranial magnetic stimulation (rTMS) of parieto-hippocampal functional connectivity in patients with major depressive disorder (MDD).
- Conditions
- Depression, Depressive Disorder, Depressive Episode, Depressive Disorder, Major
- Trial name
- NCT04081519
- Testing
- active rTMS over DLPFC, Add-on active rTMS over DLPFC, Add-on active rTMS over LPC
- Where
- Germany
- Volunteers
- 53 people
- Sponsor
- University Hospital, Bonn
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