Clinical trials: Transcranial Magnetic Stimulation
Stroke, Brain Injuries
Brain Mechanisms Underlying Reading Improvement in Central Alexia
Central alexia is a common reading disorder caused by stroke. Patients with central alexia (CA) are slow to read and make frequent errors, and have additional problems with their spoken language. This study has 3 aims: 1.
- Conditions
- Stroke, Brain Injuries, Aphasia
- Trial name
- NCT02062619
- Testing
- Computer-based behavioural word reading therapy, Real tDCS
- Where
- United Kingdom
- Volunteers
- 23 people
- Sponsor
- University College, London
Focal Dystonia, Peripheral Nervous System Disease
Association Between Focal Dystonia and Complex Regional Pain Syndrome
This study will investigate differences among people with focal dystonia (FD), complex regional pain syndrome (CRPS) and people who have both conditions to learn more about the cause of both disorders.
- Trial name
- NCT00595439
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Emotional Memory
Study on the Effect of Transcranial Magnetic Stimulation on the Perception of Emotional Images
The goal of the current clinical trial is to investigate whether transcranial magnetic stimulation (TMS) over specific brain areas can influence the perception of emotional images and emotional memory.
- Trial name
- SAME-M (NCT07191275)
- Testing
- Experimental continuous 30 Hz thetaburst transcranial magnetic stimulation, Control continuous 30 Hz thetaburst transcranial magnetic stimulation
- Where
- Switzerland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Cocaine Use Disorder, Cocaine Dependence
Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use
Objective: The goal of this clinical trial is to assess the tolerability of an accelerated intermittent theta burst stimulation (iTBS), a form of transcranial magnetic stimulation, intervention in participants with cocaine use…
- Trial name
- NCT02927236
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Amyotrophic Lateral Sclerosis
Quantitative and Repetitive TMS in ALS - Recruiting for Stage 2
Stage 1 [Enrolment closed]: The goal of this open-label pilot clinical trial is to evaluate the safety and feasibility of accelerated, repetitive transcranial magnetic stimulation (rTMS) using continuous theta-burst stimulation…
- Trial name
- QuARTS-ALS (NCT05983211)
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Major Depressive Disorder, Bipolar Disorder
Transcranial Electric Stimulation Therapy (TEST) for Treatment Resistant Depression (TRD)
Background: People with TRD are often helped by electroconvulsive therapy (ECT). But ECT can affect memory and thinking. Researchers want to study a treatment called TEST that uses less electricity.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Unipolar Major Depression
- Trial name
- NCT05172271
- Testing
- MagPro TMS Stimulator and coil, Thymatron(R) System IV, Magnetic Resonance Imaging Scanner
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- National Institute of Mental Health (NIMH)
Painful Diabetic Neuropathy
Treatment for Painful Diabetic Neuropathy
Painful diabetic neuropathy (pDN) occurs in a subset of diabetic patients, and is characterize by burning, shooting, and electric shock-like pain in the arms and legs.
- Trial name
- NCT05937984
- Testing
- Active Controlled Transcranial Magnetic Stimulation (cTMS)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Bipolar Disorder
Intermittent Theta Burst Stimulation (iTBS) for Emotion Regulation in Bipolar Disorder
The objective of this study protocol is to test whether intermittent theta-burst transcranial magnetic stimulation (iTBS-TMS) to the inferior parietal lobule (IPL) can strengthen functional connectivity with a key region in…
- Trial name
- NCT06274567
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- 2 sites in United States
- Volunteers
- 136 people
- Sponsor
- Massachusetts General Hospital
Cocaine Use Disorder (CUD)
Contingency Management Plus Deep Transcranial Magnetic Stimulation for the Treatment of Cocaine Use Disorder
The purpose of this study is to evaluate the effects of Contingency Management (CM)+transcranial magnetic stimulation (TMS) on treatment outcomes in individuals who are initial non-responders and to evaluate the effects of CM+TMS…
- Trial name
- NCT07490600
- Testing
- Contingency Management (CM), Transcranial Magnetic Stimulation (TMS) experimental
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Depression
rTMS and Cognitive Training in Youth Depression
Youth depression is a highly prevalent disorder with tremendous personal and societal costs. Guideline supported treatments are limited in efficacy and associated with side effects.
- Trial name
- NCT03708172
- Testing
- Repetitive Transcranial Magnetic Stimulation, Cognitive Training
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Transcranial Direct Current Stimulation, Functional Magnetic Resonance Imaging
Intervention Effect of High Definition Transcranial Direct Current Stimulation (HD-tDCS) on Depressive Disorder
To investigate the intervention effect of high definition transcranial direct current stimulation (HD-tDCS) on somatic symptoms in patients with depressive disorder and its underlying neural mechanism by MRI.
- Conditions
- Transcranial Direct Current Stimulation, Functional Magnetic Resonance Imaging, Depressive Disorder
- Trial name
- NCT05286645
- Testing
- High definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Anhui Medical University
Stroke, Aphasia, Non-fluent
rTMS and Multi-Modality Aphasia Therapy for Post-Stroke Aphasia
Many stroke survivors experience aphasia, a loss or impairment of language affecting the production or understanding of speech. One common type of aphasia is known as non-fluent aphasia.
- Trial name
- TMAT (NCT04901156)
- Testing
- 1Hz inhibitory rTMS, Multi-Modality Aphasia Therapy (M-MAT)
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Calgary
Alzheimer Disease, Mild Cognitive Impairment
Transcranial Magnetic Stimulation in Mild Cognitive Impairment and Alzheimer Disease
The investigators reviewed 12 years of clinical use in an outpatient neurology setting of transcranial magnetic stimulation (TMS) in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) to evaluate safety…
- Trial name
- NCT04771845
- Testing
- Transcranial Magnetic Stimulation
- Volunteers
- 73 people
- Sponsor
- The New York Memory Services
Non-specific Chronic Neck Pain, Office Workers
Alterations in Central Control of Shoulder Muscles in Office Workers With Non-specific Chronic Neck Pain
Non-specific chronic neck pain (NCNP) is commonly seen in office workers. Individuals with NCNP not only demonstrate impaired neck movement control and muscle activation, but also show abnormal scapular kinematics and muscle…
- Conditions
- Non-specific Chronic Neck Pain, Office Workers, Transcranial Magnetic Stimulation, Neuromuscular Control
- Trial name
- NCT05000177
- Testing
- 30-minute computer typing task, 30-minute rest
- Where
- Taiwan
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Healthy, Anxiety
Neuromodulation of Brain and Emotional Responses to Psychological Stress
Investigators are conducting this study to test if temporarily and non-invasively stimulating the brain will affect the emotional response to stress in healthy participants.
- Trial name
- NUMBER (NCT06603064)
- Testing
- Active continuous theta burst stimulation
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Post Traumatic Stress Disorder (PTSD)
Targeted Accelerated TMS for Post-Traumatic Stress Disorder
Post-traumatic stress disorder (PTSD) is a highly prevalent and debilitating condition among veterans and active-duty military personnel, with rates as high as 30% in certain combat-exposed populations.
- Trial name
- TAP (NCT07245641)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brigham and Women's Hospital
Executive Function Disorder, Functional Magnetic Resonance Imaging
rTMS in the Prevention and Treatment of Postoperative Executive Dysfunction
Repetitive transcranial magnetic stimulation (rTMS) is a new neuroelectrophysiological technique developed in recent years. rTMS can affect local and distant cortical function, promote regional reconstruction of cortical…
- Trial name
- NCT05575583
- Testing
- repetitive transcranial magnetic stimulation, pseudo repetitive transcranial magnetic stimulation
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Xuzhou Central Hospital
Schizophrenia
rTMS on Appetite and Cognitive Function in Schizophrenia
The weight gain and metabolic dysfunction has been vital conditions for individuals with schizophrenia. rTMS is a promising novel intervention, which have strong potentials on moderating increased appetite and cognitive deficits…
- Trial name
- NCT04714970
- Testing
- iTBS
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Central South University
Healthy
Testing the Contribution of Orbitofrontal Cortex Networks to Reward Identity Learning
This research study examines the contribution of orbitofrontal cortex (OFC) networks to learning reward identity expectations.
- Trial name
- NCT04926961
- Testing
- Real transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Healthy Adults
Efficacy and Safety of Repetitive Transcranial Magnetic Stimulation and Expressive Writing for Post-Traumatic Stress
The goal of this clinical trial is to learn if a combined treatment using repetitive transcranial magnetic stimulation (rTMS) and expressive writing works to reduce symptoms of post-traumatic stress in adults.
- Trial name
- NCT07567261
- Testing
- Repetitive Transcranial Magnetic Stimulation, Expressive writing
- Where
- 2 sites in Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Servicio Canario de Salud