Clinical trials: Transcranial Magnetic Stimulation
Schizophrenia
The Effect of Repetitive Transcranial Magnetic Stimulation in Schizophrenia
Repetitive Transcranial Magnetic Stimulation (rTMS) can modulate neuronal activity and has been shown to improve symptoms in patients with schizophrenia, but the underlying neural mechanism is unknown.This study hypothesized that…
- Trial name
- NCT03736291
- Testing
- Repetitive transcranial magnetic stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Stroke, Chronic, Aging
AMPLIFI: Adaptive Modulation of Plasticity Through Lactate and Fitness Interventions
The AMPLIFI study (Adaptive Modulation of Plasticity through Lactate and Fitness Interventions) investigates how short-term aerobic exercise influences brain plasticity and learning in older adults and stroke survivors.
- Conditions
- Stroke, Chronic, Aging, Cognitive Decline, Motor Dysfunction
- Trial name
- AMPLIFI (NCT06950060)
- Testing
- High intensity cycling, Low-intensity cycling, Health education session
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Neuropsychiatric Disorders
Reference Measurements of the Neuronal Integration Window and Anatomical and Functional MRI (Magnetic Resonance Imaging)
Our studies on MRI (Magnetic resonance imaging) biomarkers in neuropsychiatric disorders rely on reference data from control subjects which are dependent from our scanner.
- Trial name
- FIT-IRM (NCT07453108)
- Testing
- MRI (Magnetic Resonance Imaging), TMS (Transcranial Magnetic Stimulation)
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Post Traumatic Stress Disorder, Major Depressive Disorder
Accelerated TMS to a Novel Brain Target in MDD and PTSD
This is a Clinical Trial designed to evaluate novel transcranial magnetic stimulation (TMS) methods for treating depression/PTSD. TMS is an FDA-approved procedure for treatment-resistant depression.
- Trial name
- NCT03114891
- Testing
- Transcranial Magnetic Stimulation (TMS), Task, fMRI-guided TMS target
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pennsylvania
Cortical Excitability, Healthy
Assessing the Effects of Hormones on Noninvasive Transcranial Stimulation
This study is investigating how two types of non-invasive brain stimulation, transcranial electrical stimulation (TES) and transcranial magnetic stimulation (TMS), affect brain activity, and whether combining them produces…
- Conditions
- Cortical Excitability, Healthy, TMS, Menstrual Cycle
- Trial name
- NCT07635017
- Testing
- Transcranial Electrical Stimulation, Transcranial Magnetic Stimulation, TES + TMS
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Suicide, Suicidal Ideation
TMS for Suicidal Crisis in Active Duty SMs
The purpose of this study is to determine if the use of Transcranial Magnetic Stimulation (TMS) provides rapid reduction and sustained attenuation of suicidal crisis.
- Conditions
- Suicide, Suicidal Ideation, Suicidal Impulses, Suicidal Intention
- Trial name
- TMS4SI (NCT03014362)
- Testing
- Neuronetics NeuroStar XPLOR magnetic stimulator - Active
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Eisenhower Army Medical Center
Depression, Executive Dysfunction
The Antidepressant Effect of Intermittent Theta Burst Stimulation (iTBS)
The present study is a randomized placebo-controlled trial examining the effect of intermittent theta burst stimulation (iTBS) on unipolar depression. iTBS is a form of transcranial magnet stimulation.
- Trial name
- NCT05516095
- Testing
- Transcranial magnet stimulation
- Where
- Norway
- Volunteers
- 73 people
- Sponsor
- University Hospital of North Norway
Transcranial Magnetic Stimulation, Heroin Dependence
Repetitive Transcranial Magnetic Stimulation in Patients With Opioid Use Disorders
Opioid use disorder (OUD) is prevalent and causes substantial health and social burdens. Although evidence have showed the effectiveness of opioid agonist maintenance therapy in OUD, high drop-out rate and the requirement of…
- Trial name
- NCT03229642
- Testing
- Active rTMS
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Cheng-Kung University Hospital
Obsessive-Compulsive Disorder
Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation
This is a pilot study to examine the tolerability, safety and early efficacy of two forms of transcranial magnetic stimulation (TMS) for treating adolescents with Obsessive Compulsive Disorder (OCD) who have experienced limited…
- Trial name
- NCT07065669
- Testing
- Dorsal medial Prefrontal Cortex intermittent theta burst stimulation, cTBS to ROFC
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Parkinson Disease
Study of Motor Control Mechanisms in DBS-implanted Parkinson's Disease Patients
Akinesia is one of the most prominent symptom in Parkinson's Disease (PD) patients. It typically consists in a inability to initiate voluntary movement, and it affects patients' quality of life.
- Trial name
- PARKMOTEUR (NCT03714854)
- Testing
- transcranial magnetic stimulation
- Where
- France
- Volunteers
- 6 people
- Sponsor
- University Hospital, Grenoble
Basic Science
Frontal and Parietal Contributions to Proprioception and Motor Skill Learning
The purpose of this study is to understand how the different regions of the brain affect our sense of limbs in space (proprioception) and in turn our hand movements (motor skill learning).
- Trial name
- NCT05739994
- Testing
- Theta burst transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Indiana University
Mild Cognitive Impairment
Transcranial Magnetic Stimulation and Cognitive Stimulation in Mild Cognitive Impairment
This study evaluates the effect of 5Hertz (Hz) repetitive Transcranial Magnetic Stimulation (rTMS) on Left Dorsolateral Prefrontal Cortex enhancing Cognitive Stimulation in Mild Cognitive Impairment.
- Trial name
- rTMS&MCI (NCT03906903)
- Testing
- Repetitive Transcranial Magnetic Stimulation, Cognitive Stimulation
- Where
- Mexico
- Volunteers
- 20 people
- Sponsor
- Universidad Autonoma de Queretaro
Major Depressive Disorder
The Utility of Concurrent TBS/fNIRS for Antidepressant Treatment Optimization
Repetitive transcranial magnetic stimulation (rTMS) with theta bursts (i.e. TBS) of the dorsolateral prefrontal cortex (DLPFC) is an innovative treatment for major depressive disorder (MDD). Indeed, the U. S.
- Trial name
- NCT04526002
- Testing
- Theta-burst stimulation (TBS)
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Dr Georg Kranz
Depression
fMRI Accelerated TMS Depression
This study aims to investigate whether phenotypic-related brain states revealed by a novel INSCAPE ("Individualized Network-based Single-frame Coactivation Pattern Estimation") neuroimaging method in Major Depressive Disorder…
- Trial name
- NCT06562153
- Testing
- Neuroimaging with Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Vegetative State, Minimally Conscious State
Transcranial Brain Stimulation in Vegetative State Patients
The aim of this study is to determine whether transcranial brain stimulations, such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), are effective in terms of EEG…
- Trial name
- NCT01820923
- Testing
- Transcranial direct current stimulation (tDCS), Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Post-stroke Depression
A Study of rTMS Personalized Precision Treatment of Post-stroke Depression
This is a multicenter, randomized trial aims to reveal the efficacy and safety of Repetitive transcranial magnetic stimulation (rTMS) individualized therapy based on the 'emotional loop destabilization' mechanism of PSD .One…
- Trial name
- NCT03256305
- Testing
- "personalized" rTMS+drug treatment, Traditional rTMS +drug treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhujiang Hospital
Autism Spectrum Disorders
Autism Spectrum Disorders: Double Blind Randomized Placebo-control Active Pilot Study of Transcranial Magnetic Stimulation Applied to the Superior Temporal Sulcus
Difficulties in social interactions are the core feature of autism spectrum disorder (ASD) and are characterized by abnormal social perception, mainly concerning eye gaze.
- Trial name
- STIMAUT (NCT04442061)
- Testing
- Transcranial magnetic stimulation, MRI, Neuronavigation
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Major Depressive Disorder
Optimizing Brain Excitability in Depression
The goal of this study is to improve depression treatment by establishing reliable prefrontal excitability markers through Targeting with Automated Real-time Guidance for Enhancing TEPs (TARGET).
- Trial name
- TARGET (NCT07242105)
- Testing
- Active Single-Pulse TMS, TARGET-optimized TMS, Non-optimized (Open-Loop) TMS
- Where
- 2 sites in United States
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Stanford University
Opioid Withdrawal, Chronic Pain
ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain
This study will sequentially evaluate three novel and scalable interventions for at-risk individuals on long term opioid therapy for chronic pain: (1) low-dose transdermal buprenorphine initiation without a period of opioid…
- Trial name
- ACTION (NCT06442566)
- Testing
- Buprenorphine Patch, Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Amyotrophic Lateral Sclerosis (ALS)
Transcranial Static Magnetic Stimulation (tSMS) and Potential Theranostic Biomarkers in Amyotrophic Lateral Sclerosis.
The objective of the present study is to assess the efficacy of tSMS in ALS patients. This will be achieved by monitoring: levels of NF-L and other potential innovative biomarkers, clinical progression, trough ALSFRS-R.
- Trial name
- NCT06834269
- Testing
- Transcranial magnetic stimulation (tSMS)
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
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