Clinical trials: Transcranial Magnetic Stimulation
Depression
Transcranial Magnetic Stimulation in Major Depression With EEG and Near Infrared Spectroscopy (NIRS) Monitoring
This a 12- week study (1-4 week screening, 6 weeks treatment, 2 weeks follow-up) outpatient open label clinical trial. Twenty-five subjects diagnosed with depression with a Montgomery Asberg Depression Rating Scale (MADRAS) score…
- Trial name
- NCT01192685
- Testing
- Transcranial Magnetic Stimulation (TMS), near infrared spectroscopy (NIRS)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Boston University
Multiple Sclerosis, Fatigue
Amantadine and Transcranial Magnetic Stimulation for Treating Fatigue in Multiple Sclerosis
Multiple Sclerosis (MS) is the most frequent cause of non-traumatic disability in people under 55 years of age. Fatigue is the most frequent and disabling symptom in the disease, and for which there is no effective treatment.
- Trial name
- FETEM (NCT05809414)
- Testing
- Transcranial Magnetic Stimulation, Amantadine Hydrochloride 100 mg (milligrams) Oral Capsule
- Where
- 4 sites in Spain
- Volunteers
- 144 people
- Sponsor
- Hospital San Carlos, Madrid
Acquired Brain Injury, Stroke
TMS-EEG for Cortical Excitability
This research study is being done to look at the safety and diagnostic benefit of conducting an TMS(transcranial magnetic stimulation)-EEG measured before and after a brief experimental stimulation session using investigational…
- Conditions
- Acquired Brain Injury, Stroke, Traumatic Brain Injury, Healthy
- Trial name
- NCT05472363
- Testing
- Electroencephalogram, Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- Mayo Clinic
Multiple Sclerosis
Repetitive Transcranial Magnetic Stimulation for Lower Limb Spasticity in Multiple Sclerosis Patients
Leg spasticity is common problem encountered with a large proportion of patients suffering with multiple sclerosis (MS) with an increasing severity as the disease progresses.
- Trial name
- NCT02747914
- Testing
- Transcranial magnetic stimulation, Conventional exercise
- Where
- Serbia
- Volunteers
- 40 people
- Sponsor
- University of Belgrade
Anxiety, Transcranial Magnetic Stimulation Repetitive
Neuroimage-guided Dual-target Continuous Theta Burst Stimulation for Generalized Anxiety Disorder
The aim of this clinical trial was to determine whether image-guided dual-target cTBS is effective for anxiety disorders. The main questions it aims to answer are: 1. Does dual-target cTBS improve patients' anxiety symptoms? 2.
- Trial name
- NCT06699706
- Testing
- Continuous theta-burst stimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Anhui Medical University
Parkinson Disease, Depression
Navigated Repetitive Transcranial Magnetic Stimulation for Parkinson's Disease With Depression or Cognitive Impairment
Depressive symptoms are common non-motor symptoms in patients with Parkinson's disease and seriously affect the quality of life and prognosis of patients.
- Conditions
- Parkinson Disease, Depression, Cognitive Impairment
- Trial name
- NCT04707378
- Testing
- repetitive transcranial magnetic stimulation(rTMS)
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Guangdong Provincial People's Hospital
Post Traumatic Stress Disorder
Effect of TMS on PTSD Biomarkers
The study will (1) assess feasibility of a TMS treatment in an underserved population; (2) determine if this TMS treatment protocol improves PTSD symptoms and biological markers of PTSD such as brain functioning and startle…
- Trial name
- NCT04563078
- Testing
- Transcranial Magnetic Stimulation (TMS)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Nicotine Dependence
Pilot Study of Transcranial Magnetic Stimulation (TMS) in Nicotine Addiction
Background: Treatment for nicotine addiction is characterized by high rates of relapse. New treatment therapies for nicotine addiction are exploring the use of brain scanning equipment to control and decrease nicotine and…
- Trial name
- NCT01031693
- Testing
- Transcranial Magnetic Stimulation
- Where
- 2 sites in United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Chronic Fatigue Syndrome, Intensive Care Unit
Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability
Chronic fatigue is the most common and debilitating symptom in intensive care unit (ICU) survivors. Indeed, it has been widely reported that patients who stayed in ICU for prolonged periods report a feeling of tiredness for…
- Conditions
- Chronic Fatigue Syndrome, Intensive Care Unit, Muscle
- Trial name
- FatCovid-19 (NCT04363606)
- Testing
- Questionnaires, blood test, Maximal effort test
- Where
- 8 sites in France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Older Patients, Cognitive Impairment
Repetitive Transcranial Magnetic Stimulation and Postoperative Neurocognitive Recovery
Patients with preoperative cognitive impairment are at increased risks of delayed neurocognitive recovery (DNR) and postoperative neurocognitive disorder (POCD).
- Conditions
- Older Patients, Cognitive Impairment, Repetitive Transcranial Magnetic Stimulation, Delayed Neurocognitive Recovery
- Trial name
- NCT06482749
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- 3 sites in China
- Volunteers
- 568 people
- Sponsor
- Peking University First Hospital
Schizophrenia
Repetitive Transcranial Magnetic Stimulation and Intermittent Theta Burst (iTBS) in Schizophrenia
The pilot studies have showed that theta burst stimulation (TBS) can have the more rapid and durable effects to the apply traditional rTMS protocols.
- Trial name
- NCT01315587
- Testing
- repetitive Transcranial Magnetic Stimulation (Magstim rapid2 ), repetitive Transcranial Magnetic Stimulation (Magstim rapid2), repetitive Transcranial Magnetic Stimulation(Magstim rapid2)
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- University of Tehran
Tic Disorder
Teen and Adult Tic TMS Study
This project investigates safety, tolerability, and efficacy signals of accelerated continuous theta burst stimulation (cTBS), a form of inhibitory repetitive transcranial magnetic stimulation (rTMS), for patients with Tourette…
- Trial name
- NCT07839377
- Testing
- cTBS (accelerated continuous theta burst stimulation)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, San Francisco
Cerebrovascular Accident
Predictors of Treatment Response of Motor Sequels After a Stroke
The cerebrovascular accident (CVA) is currently the leading cause of death in Brazil and it is estimated that there are about 62 million stroke survivors worldwide.
- Trial name
- NCT02432521
- Testing
- Conventional rehabilitation program from IMREA
- Where
- Brazil
- Volunteers
- 49 people
- Sponsor
- University of Sao Paulo General Hospital
Depressive Disorder, Depression
Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder
This is a double-blind, sham controlled, multi-center study to confirm the safety and efficacy of synchronized transcranial magnetic stimulation (sTMS) for the treatment of patients currently experiencing an episode of depression…
- Conditions
- Depressive Disorder, Depression, Depressive Disorder, Major, Depressive Episode
- Trial name
- NCT03288714
- Testing
- Synchronized Transcranial Magnetic Stimulation (sTMS)
- Where
- 14 sites in United States
- Volunteers
- 121 people
- Sponsor
- Wave Neuroscience
Bulimia Nervosa
Efficiency of Repetitive Transcranial Magnetic Stimulation (rTMS) in Bulimia
Bulimia nervosa is defined by recurrent episodes of binge eating followed by compensatory behaviors (such as induced vomiting) to prevent weight gain.
- Trial name
- rTMS&bulimia (NCT01530906)
- Testing
- Repetitive transcranial Magnetic Stimulation (rTMS)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Montpellier
Ultra-marathon Runners
Fatigability Compared Men and Women Induced According to the Distance Traveled on an Ultra-marathon in the Mountains
Acute physiological consequences of ultra-marathon running are still unknown, particularly in women. Some studies have suggested that the proportion of fatigue attributable to peripheral and central mechanisms varies between…
- Trial name
- UTMB_2019 (NCT04025138)
- Testing
- Neuromuscular tests in isometric mode, Transcranial Magnetic Stimulation (TMS), Neuromuscular fatigue assessment test
- Where
- France
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Stroke
rTMS Combined With BWSTT in Stroke With Body Weight Supported Treadmill Training (BWSTT) After Stroke
The study will enroll 5 individuals post-stroke to examine the feasibility and efficacy of a high frequency repetitive transcranial magnetic stimulation (rTMS) combined with body weight supported treadmill training.
- Trial name
- NCT03441334
- Testing
- High Frequency rTMS
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Texas Woman's University
Ischemic Stroke
Effectiveness of Theta Burst Stimulation For Upper and Lower Extremity Recovery in Stroke
This single-center, single-blind, randomized, sham-controlled clinical trial will include 60 patients aged >45 years who are within 3 months of a first-ever middle cerebral artery ischemic stroke.
- Trial name
- NCT07834333
- Testing
- Continuous Theta Burst Stimulation (cTBS), Intermittent Theta Burst Stimulation (iTBS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ankara Etlik City Hospital
Cognitive Decline, Cognitive Impairment
Effects of Accelerated rTMS on Cognitive Function
Cognitive impairment, including mild cognitive impairment (MCI) and mild dementia, is a growing public health challenge with limited effective treatment options.
- Trial name
- NCT07547319
- Testing
- TMS
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- San Francisco Neurology and Sleep Center
Obsessive-Compulsive Disorder
rTMS Over the Supplementary Motor Area for Treatment-resistant Obsessive-compulsive Disorder.
The aim of this study is to investigate the effectiveness of low-frequency (1Hz) rTMS (repetitive transcranial magnetic stimulation) over the pre-SMA (pre-supplementary motor area) in a sample of treatment-resistant OCD patients…
- Trial name
- rTMSOCD (NCT03211221)
- Testing
- rTMS (repetitive transcranial magnetic stimulation)
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- CNS Onlus
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