Clinical trials: Transcranial Magnetic Stimulation
Obsessive-Compulsive Disorder
Transcranial Magnetic Stimulation (TMS) and Obsessive Compulsive Disorder (OCD)
This study will evaluate the clinical efficacy of functional Magnetic Resonance Imaging (fMRI) guided 1 Hz repetitive Transcranial Magnetic Stimulation (rTMS) applied to the Supplementary Motor Area (SMA) in OCD patients who have…
- Trial name
- NCT00106249
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- New York State Psychiatric Institute
Treatment Resistant Depression
Establishing a Dose-response Relationship With Accelerated Transcranial Magnetic Stimulation
This study evaluates an accelerated schedule of theta-burst stimulation using a transcranial magnetic stimulation device for treatment-resistant depression.
- Trial name
- NCT04243798
- Testing
- Active TBS-DLPFC
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Stanford University
Stroke
Exercise and Brain Stimulation for Post-stroke Depression
This project will assess the effects of aerobic exercise training (AET), repetitive transcranial magnetic stimulation (rTMS) or their combination on depressive severity as well as locomotor function in persons with post-stroke…
- Trial name
- NCT03056287
- Testing
- Aerobic exercise, Repetitive transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Medical University of South Carolina
Stroke
A Novel Approach for Brain Stimulation in Severe Stroke
The long-term goal of this project is to develop upper limb rehabilitation interventions that can be utilized for stroke survivors, specifically survivors with more severe limitations in use of their affected upper limb.
- Trial name
- NCT03868410
- Testing
- New Repetitive Magnetic Stimulation (rTMS) Approach, Conventional Repetitive Magnetic Stimulation (rTMS) Approach
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- The Cleveland Clinic
Transcranial Magnetic Stimulation
cTBS/fMRI Study of Hierarchical Control in the PFC
The objective of this study is to examine the effect of transcranial magnetic stimulation (TMS) on the prefrontal cortex and posterior parietal cortex.
- Trial name
- NCT04464473
- Testing
- transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Florida State University
Chronic Obstructive Pulmonary Disease
Comparison of Repetitive Magnetic Stimulation and Exercise on Quadriceps Function in COPD
Background Chronic Obstructive Pulmonary Disease (COPD) patients develop leg weakness and a reduced walking capacity, due to reduced leg muscle oxygen-utilising capacity (OUC).
- Trial name
- NCT00737698
- Testing
- Exercise, Repetitive magnetic stimulation
- Where
- United Kingdom
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Neurofibromatosis 1
Antioxidant Therapy With N-acetylcysteine for Children With Neurofibromatosis Type 1
Children with neurofibromatosis type 1 (NF1) commonly suffer from the effects of cognitive, behavioral, and motor impairments. At present, there is no specific treatment for this NF1 complication.
- Trial name
- DoDNAC (NCT04481048)
- Testing
- N-Acetyl cysteine
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Spasticity
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment of Post-Stroke Spasticity
Spasticity is a common complication of stroke affecting quality of life. Spasticity involves exaggerated stretch reflexes that create stiffness in muscles with associated loss of motion and functional control.
- Trial name
- NCT02268461
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Minnesota
Generalized Anxiety Disorder
Transcranial Magnetic Stimulation Treatment for Generalized Anxiety Disorder
This study is investigating a new indication of Transcranial Magnetic Stimulation (TMS) by conducting a pilot randomized-controlled trial (RCT) comparing structural neuronavigation-directed TMS to Sham-TMS Placebo therapy for…
- Trial name
- NCT01659736
- Testing
- TMS
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Hartford Hospital
Traumatic Brain Injury
rTMS to Improve Cognitive Function in TBI
This project will study 40 Veterans identified with symptoms understood to characterize mild to moderate Traumatic Brain Injury (TBI) including Post Traumatic Stress Disorder (PTSD).
- Trial name
- rTMSTBI (NCT02152540)
- Testing
- rTMS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- VA Office of Research and Development
Misophonia, Emotion Dysregulation
Identifying the Optimal Neural Target for Misophonia Interventions
Misophonia, the inability to tolerate certain repetitive aversive sounds that are common, is gaining recognition as a debilitating condition. It is not a well-understood condition and there are no known treatments.
- Trial name
- NCT04348591
- Testing
- Cognitive Restructuring, neurostimulation
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Duke University
Smoking Cessation, Nicotine Addiction
Circuitry-Guided Smoking Cessation in Schizophrenia
In a double-blinded, randomized, parallel controlled design, patients with schizophrenia spectrum disorder will be exposed to active or sham repetitive transcranial magentic stimulation (TMS) which was guided by functional…
- Conditions
- Smoking Cessation, Nicotine Addiction, Schizophrenia
- Trial name
- NCT03281629
- Testing
- Active TMS stimulation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Maryland, Baltimore
Tinnitus
Regulating Homeostatic Plasticity and the Physiological Response to rTMS
This device-study includes a pilot, physiological investigation of normal human subjects. The aim is to determine how existing non-invasive neuromodulation devices affect brain circuitry as measured by EEG recording.
- Trial name
- NCT03309696
- Testing
- active tDCS and active rTMS
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Normal Physiology
Task-dependent Effects of TMS on the Neural Biomarkers of Episodic Memory
Background: Transcranial magnetic stimulation (TMS) of the brain has been used to change the activity and connections in the brain to improve memory.
- Trial name
- NCT04694131
- Testing
- TMS
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cocaine Use Disorder, Cocaine Dependence
Theta-Burst Stimulation as a Treatment for Reducing Cocaine Use
Objective: The goal of this clinical trial is to assess the tolerability of an accelerated intermittent theta burst stimulation (iTBS), a form of transcranial magnetic stimulation, intervention in participants with cocaine use…
- Trial name
- NCT02927236
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Knee Osteoarthritis, Chronic Pain
Motor Cortex Plasticity and the Effect of Deep Intramuscular Needling Stimulation Therapy (DIMST) in Osteoarthritis Pain
The aim of this study is to evaluate the cortical excitability in pain of knee osteoarthritis (OA), as well as the effect of one session of a kind of electroacupuncture (deep needling intramuscular stimulation therapy - DIMST) in…
- Trial name
- NCT01855958
- Testing
- DIMST
- Where
- Brazil
- Volunteers
- 26 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Stimulant Use Disorder, Substance-related Disorders
Treating Stimulant Addiction With Repetitive Transcranial Magnetic Stimulation
The purpose of this study is to establish a new treatment (repetitive transcranial stimulation (rTMS)) for Veterans with stimulant use disorder (SUD).
- Trial name
- VA-StARTS (NCT04228276)
- Testing
- Repetitive transcranial magnetic stimulation (rTMS)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Stroke, Hemiparesis
Perinatal Stroke: Understanding Brain Reorganization
The incidence of perinatal stroke is relatively common, as high as 1 in 2,300 births, but little is known about the resulting changes in the brain that eventually manifest as cerebral palsy (CP).
- Trial name
- NCT02743728
- Testing
- Magnetic Resonance Imaging, Transcranial Magnetic Stimulation, General Movement Assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Major Depressive Disorder
iCBT With TMS in Patients With MDD
Major Depressive Disorder (MDD) is a common mental health diagnosis. While there are many approaches to the treatment of MDD, current treatments of MDD often do not substantially reduce depressive symptoms among those in need of…
- Trial name
- NCT05988619
- Testing
- Transcranial Magnetic Stimulation, Internet-Based Cognitive Behavioral Therapy, Psychoeducation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Los Angeles
Mild Cognitive Impairment
Interleaved TMS-fMRI for Hippocampal Stimulation: Modeling Dose-Response Relationship in Amnestic Mild Cognitive Impairment
Emerging evidence indicates that dysfunction of hippocampal synaptic plasticity, which precedes neuronal degeneration during the progression of Alzheimer's disease (AD), underlies the hallmark cognitive impairment.
- Trial name
- TMS-fMRI (NCT05515952)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Arizona