Clinical trials: Transcranial Magnetic Stimulation
Major Depressive Disorder
Treatment of Major Depressive Disorder With Bilateral Theta Burst Stimulation
This is a randomized, double-blind, sham-controlled multicenter clinical trial. The aim is to provide evidence for efficacy of TBS in the treatment of patients with major depression.
- Trial name
- TBS-D (NCT04392947)
- Testing
- Transcranial Magnetic Stimulation
- Where
- 7 sites in Germany
- Volunteers
- 238 people
- Sponsor
- University Hospital Tuebingen
Stroke, Hemiplegia
Asymmetrical Gait Training After Pediatric Stroke
The purposes of this pilot research study are 1. To begin to test if two different types of physical therapy might have different results in children and adolescents who have had a prior stroke, and 2.
- Trial name
- NCT01827436
- Testing
- Conventional physical therapy, Asymmetrical gait training
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Children's Hospital of Philadelphia
Decision Making
Transcranial Magnetic Stimulation of the Prefrontal Cortex: Effects on Risky Decision Making and Temporal Discounting.
The main objective of this study is to examine the effects of magnetic stimulation on the prefrontal cortex. We plan to use low frequency, repeated transcranial magnetic stimulation (1 Hz rTMS) to temporarily inhibit activity in…
- Trial name
- NCT01098864
- Testing
- transcranial magnetic stimulation
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Arkansas
Spinocerebellar Ataxias
Efficacy of Cerebellar Transcranial Magnetic Stimulation to Treat Hereditary Spinocerebellar Ataxias
Spinocerebellar ataxia (SCA) is a type of autosomal dominant ataxia and there is currently no effective treatment. The goal of this clinical trial is to learn the efficacy of navigated iTBS (Intermittent theta-burst stimulation)…
- Trial name
- NCT06898645
- Testing
- navigated iTBS (Intermittent theta-burst stimulation) targeting the cerebellum
- Volunteers
- 80 people
- Sponsor
- Xijing Hospital
Amphetamine Addiction
The Diagnostic Assessment and Intervention Study of Amphetamine Type Stimulus
The purpose of this research is to inspire new medical ideas using brain image technology for the treatment of Amphetamine Type Stimulus addition, at the same time lowing the addition damage.
- Trial name
- NCT02285556
- Testing
- psychological rehabilitation training, physical and neurological rehabilitation training, rTMS 10HZ high frequency stimulation
- Where
- China
- Volunteers
- 560 people
- Sponsor
- Shanghai Mental Health Center
Depression - Major Depressive Disorder, Cognitive Flexibility
Cognitive Flexibility in Depression and TMS Response
The primary aim of this study is to determine the level of cognitive flexibility in patients with TRD before treatment and to explore whether there is a relationship with their response to TMS treatment.
- Conditions
- Depression - Major Depressive Disorder, Cognitive Flexibility, Treatment Response, Side Effects
- Trial name
- CogFelx_TMS (NCT06775054)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Gulhane Training and Research Hospital
Post COVID-19 Condition
Post COVID-19 Syndrome Treatment With Variable Pulse Transcranial Magnetic Stimulation
The purpose of this study is to test if Variable Pulse TMS (Transcranial Magnetic Stimulation) can result in objective improvements in patients with Post COVID Syndrome (PCS).
- Trial name
- NCT06865222
- Testing
- Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) - 2 weeks, Electromagnetic Brain Pulsing Variable Pulse Protocol (EMBP) - 4 weeks
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Parkinson Disease (PD)
Transcranial Magnetic Stimulation for Freezing of Gait in Parkinson's Disease
This study evaluated transcranial magnetic stimulation (TMS) for freezing of gait in patients with Parkinson's disease. Participants with Parkinson's disease and freezing of gait received conventional TMS protocols, and their…
- Trial name
- PD-FOG-TMS (NCT07731841)
- Testing
- Primary Motor Cortex Transcranial Magnetic Stimulation, Spinal Cord Magnetic Stimulation, SMA TMS
- Where
- China
- Volunteers
- 85 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Post-delirium Cognitive Impairment
Prefrontal Theta Burst Stimulation to Improve Cognitive Impairment After ICU Delirium
Many older adults who survive a stay in the intensive care unit (ICU) experience delirium, a sudden change in attention and awareness caused by serious illness.
- Trial name
- NCT07452939
- Testing
- Intermittent theta burst stimulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Florida
Fibromyalgia, Irritable Bowel Syndrome
Efficacy of Transcranial Magnetic Stimulation (TMS) in Chronic Idiopathic Pain Disorders
Objectives : To investigate the analgesic effects of repeated sessions of unilateral rTMS in patients with chronic pain syndrome due to fibromyalgia, IBS or burning mouth syndrome. Primary outcome will be numerical pain scores.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Burning Mouth Syndrome
- Trial name
- NCT00374673
- Testing
- Repetitive transcranial magnetic stimulation
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospital Ambroise Paré Paris
ALS (Amyotrophic Lateral Sclerosis)
Non-invasive Brain Stimulation and Exercise Intervention for Patients With Motor Neuron Disease
Motor neuron disease (MND) is a progressive neurological disorder involving degeneration of motor neurons, leading to muscle weakness, speech and swallowing difficulties, and respiratory failure.
- Trial name
- NCT07067229
- Testing
- Personalized rTMS, Standard rTMS
- Where
- Thailand
- Volunteers
- 100 people
- Sponsor
- Chulalongkorn University
Healthy Subjects, Functional Dyspepsia
Cerebral Cortical Influences on Autonomic Function
This is an exploratory neurophysiological study that will determine the impact of non-invasive brain stimulation on autonomic regulation, with a focus on gastrointestinal function.
- Conditions
- Healthy Subjects, Functional Dyspepsia, Irritable Bowel Syndrome
- Trial name
- NCT03869372
- Testing
- rTMS
- Where
- United States
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- David Levinthal
Stroke
Repetitive Transcranial Magnetic Stimulation (rTMS) to Promote Hand Recovery in Stroke
Paralysis following stroke stems not only from the loss of neurons killed by the stroke but also from the loss of neurons lying dormant in the stroke hemisphere.
- Trial name
- rTMS (NCT00913211)
- Testing
- rTMS, Motor learning training, rTMS and Tracking
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Minnesota
Mood Disorders
Efficacy and Safety of TMS and Deep TMS Treatment for Psychiatric and Neurological Disorders
The goal of this study is to examine the efficacy and safety of transcranial magnetic stimulation (TMS) and deep TMS (dTMS) for treatment of different psychiatric and neurological disorders.
- Trial name
- NCT02917499
- Testing
- TMS
- Where
- Croatia
- Volunteers
- 228 people
- Sponsor
- Sveti Ivan Psychiatric Hospital
Major Depressive Disorder
Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic
The current study aims to assess the feasibility, acceptance and clinical outcomes of a practical high-dose aiTBS protocol, including tapering treatments and symptom-based relapse prevention treatments, in patients with unipolar…
- Trial name
- NCT04384965
- Testing
- MagPro X100 Stimulator, B70 Fluid-Cooled Coil
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder (MDD)
Accelerated TMS for Treatment-Resistant ECT
This study investigates whether an additional treatment using transcranial magnetic stimulation (TMS) can help severely depressed patients who did not respond well to electroconvulsive therapy (ECT).
- Trial name
- A-TREC (NCT07115628)
- Testing
- Transcranial Magnetic Stimulation
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Universitair Ziekenhuis Brussel
Depression, Treatment Resistant
rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression
The goal of this clinical trial is to learn if Transcranial Magnetic Stimulation (TMS) to part of the brain called the ventromedial prefrontal cortex (VMPFC) can treat a symptom called rumination in adults with major depression…
- Trial name
- NCT06511544
- Testing
- Transcranial magnetic stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Indiana University
Mild Cognitive Impairment
Comparison of Two Non-invasive Neuromodulation Techniques as Synergistic Therapy to Cognitive Stimulation in Amnestic Mild Cognitive Impairment (aMCI)
This is a comparative, double-blind, randomized controlled clinical trial for people with Amnestic Mild Cognitive Impairment. The investigators will compare the effects of two non-invasive neuromodulation techniques (Repetitive…
- Trial name
- NCT06467253
- Testing
- 1. rTMS + CS, 3. tDCS + CS
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto Nacional de Psiquiatría Dr. Ramón de la Fuente
Stroke
Influence of Theta Burst Stimulation and Carbidopa-Levodopa on Motor Performance in Stroke Patients
This study will examine whether transcranial magnetic stimulation (TMS) of the brain used in combination with carbidopa-levodopa is more effective in temporarily improving the speed of hand movement in stoke patients than TMS…
- Trial name
- NCT00366184
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Stroke
Repetitive Transcranial Magnetic Stimulation in Spatial Attention After Stroke
Randomized Controlled Trial (RCT) aiming at assessing the efficacy of a novel rehabilitation protocol, based on repetitive transcranial magnetic stimulation (r- TMS) in combination with a conventional cognitive treatment (CCT).
- Trial name
- r-TMS (NCT04080999)
- Testing
- r-TMS
- Where
- 2 sites in Italy
- Volunteers
- 56 people
- Sponsor
- Azienda Usl di Bologna
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