Clinical trials: Treatment as Usual (TAU)
Psychotic Disorders, Psychosis
CBT to Reduce Insomnia and Improve Social Recovery in Early Psychosis
Sleep disturbances and cognitive dysfunction are consistently reported as extremely troublesome aspects of psychotic illnesses. While sleep disturbances are not included in definitions of psychosis they are associated with poor…
- Conditions
- Psychotic Disorders, Psychosis, Sleep
- Trial name
- CRISP (NCT04180709)
- Testing
- Sleepio
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Cambridge
Depressive Episode
Chronotherapy for Depressive Episodes
Evidence-based treatments for depression, such as antidepressive medication, usually have a latency of 4 to 6 weeks before they achieve a therapeutic effect.
- Trial name
- NCT05691647
- Testing
- Chronotherapy, Treatment as usual
- Where
- Norway
- Volunteers
- 76 people
- Sponsor
- St. Olavs Hospital
Male Prison Inmates
The Effects of the GPS Program in Offenders
This randomized controlled trial aimed to assess the efficacy of a 40-session cognitive-behavioral group program, Growing Pro-Social (GPS), in reducing early maladaptive schemas and cognitive distortions (primary outcomes), as…
- Trial name
- GPS (NCT03013738)
- Testing
- Growing Pro-Social Program, Treatment As Usual
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- University of Coimbra
Fatigue, Dyspnea
TaiChi-DTx for Treating Long Covid Symptoms
The randomized controlled trial will be conducted to evaluate the effectiveness of a Multi-domain Tai Chi Digital Therapy for treating the individuals suffering from the long term COVID-19 syndrome (Long COVID).
- Conditions
- Fatigue, Dyspnea, Cognitive Impairment, Muscle Pain
- Trial name
- TaiChi-DTx (NCT05419219)
- Testing
- the multi-domain Tai Chi Digital therapy Software Application
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tim Shi
Opioid Use Disorder
START NOW in the Treatment of Opioid Addicted Individuals
This investigation involves a partially randomized clinical trial examining the effectiveness of combining buprenorphine/naloxone MAT with START NOW, a skills-based psychosocial intervention modified specifically for the…
- Trial name
- NCT05552040
- Testing
- START NOW Group
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- Carilion Clinic
Violence
A Virtual Reality Brief Violence Intervention: Preventing Gun Violence Among Violently Injured Adults
The overall aim of the proposed project is to develop and evaluate the effectiveness of Brief Violence Intervention-Virtual Reality (BVI-VR) for reducing firearm-related violence, re-injury, and mortality among victims of…
- Trial name
- NCT06239285
- Testing
- Brief Violence Intervention VR (BVI-VR), Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Virginia Commonwealth University
Intimate Partner Violence
Evaluating Interventions for Intimate Partner Violence Use in Washington State
Intimate partner violence (IPV), specifically physical and psychological aggression toward an intimate partner, represents a public health crisis that affects millions of Americans each year.
- Trial name
- NCT06526247
- Testing
- Strength at Home (SAH), Treatment as usual for IPV
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Boston University
Drug Use
The Impact of Alternative Social Assistance Disbursement on Drug-related Harm
This study evaluates whether altering the timing and frequency of social assistance disbursement reduces drug related-harms that increase on the days surrounding monthly synchronized government social assistance cheque issue.
- Trial name
- TASA (NCT02457949)
- Testing
- Non-synchronized social assistance receipt, cheque divided into two equal disbursements
- Where
- Canada
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Depression, Anxiety
Digital Cognitive Behavioral Therapy for Depressive Disorders
This study aims to explore the effectiveness of digital interventions combined with medication in the treatment of patients with depressive disorders.
- Trial name
- NCT06423443
- Testing
- Digital Cognitive Behavioral Therapy, Health Education, TAU
- Sponsor
- Adai Technology (Beijing) Co., Ltd.
Challenging Behaviour
Evaluation of Parent Intervention for Challenging Behaviour in Children With Intellectual Disabilities (EPICC-ID)
Children with intellectual disabilities are likely to present with challenging behaviour. Parent mediated interventions have shown utility in influencing child behaviour, although there is a paucity of UK research into…
- Trial name
- NCT03086876
- Testing
- Level 4 Stepping Stones Triple P (SSTP)
- Where
- 4 sites in United Kingdom
- Volunteers
- 261 people
- Sponsor
- University College, London
Depression, Anxiety Disorders
Understanding the Person, Exploring Change Across Psychotherapies
Identifying predictors and understanding mechanisms of change will inform referral to psychotherapy, triage and right-siting by helping clinicians to understand how their patients are likely to benefit from clinical…
- Trial name
- Xchange (NCT04106713)
- Testing
- Individual Psychotherapy, Internet-delivered Cognitive Behavioural Therapy (iCBT), Group Cognitive Behavioural Therapy (group CBT)
- Where
- Singapore
- Volunteers
- 250 people
- Sponsor
- Institute of Mental Health, Singapore
Autism Spectrum Disorder
Improving the Part C Early Intervention Service Delivery System for Children With ASD
Despite strong consensus that early, specialized intervention for children with autism spectrum disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely…
- Trial name
- NCT05114538
- Testing
- Reciprocal Imitation Training
- Where
- 4 sites in United States
- Volunteers
- 440 people
- Sponsor
- Rush University Medical Center
Obsessive-Compulsive Disorder
Effect of SC-ICBT for Adults With OCD：A Three-Arm Randomized Controlled Trial
The goal of this clinical trial is to learn about the efficacy and cost-effectiveness of stepped-care Internet-based cognitive behavioral therapy (SC-ICBT) compared with Cognitive Behavioral Group Therapy (CBGT) and conventional…
- Trial name
- NCT05528224
- Testing
- stepped-care Internet-based cognitive behavioral therapy(SC-ICBT), Cognitive Behavioral Group Therapy (CBGT), conventional medical treatment (TAU)
- Where
- China
- Volunteers
- 46 people
- Sponsor
- Shanghai Mental Health Center
Emotional Disorder
Unified Protocol for Emotional Disorders: HiTOP-PRO Trial
This randomised, parallel-group clinical trial evaluates the effects of the Unified Protocol (UP), a transdiagnostic cognitive-behavioural psychotherapy, on dimensional symptom outcomes aligned with the Hierarchical Taxonomy of…
- Trial name
- UP-HITOP (NCT07557017)
- Testing
- Unified Protocol, Treatment as usual (TAU)
- Where
- Czechia
- Volunteers
- 90 people
- Sponsor
- National Institute of Mental Health, Czech Republic
Stress Disorders, Post-Traumatic
Adapting Treatment Delivery to Improve Retention in Evidence-Based PTSD Treatment
Posttraumatic stress disorder (PTSD) is prevalent among Veterans and effective evidence-based psychotherapies (EBPs) for PTSD have been implemented within the Veterans Health Administration (VHA).
- Trial name
- NCT06335589
- Testing
- EBP-Massed, EBP-TAU
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- VA Office of Research and Development
Smoking Cessation
Rural COPD E-Visit Study
The purpose of this study is to evaluate an electronic visit (e-visit) for COPD screening and for quitting smoking. Participants will be randomly assigned to receive either the smoking cessation e-visit or not.
- Trial name
- NCT06236347
- Testing
- Smoking cessation e-visit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Deviant Sexual Behavior
Pilot Randomized Controlled Trial of the INSIGHT Program
This randomized controlled trial aimed to assess the efficacy of a new intervention program for perpetrators of child sexual abuse: the INSIGHT Program.
- Trial name
- NCT06255158
- Testing
- INSIGHT Program, Treatment As Usual (TAU)
- Where
- Portugal
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minho
Depressive Disorder
Effectiveness of a Brief Psychological Mindfulness Based Intervention for the Treatment of Depression in Primary Care
The aim of this study is to assess and compare a mindfulness low-intensity (4 weeks) psychological intervention for the treatment of depression in Primary Care between different groups: a mindfulness intervention applied face to…
- Trial name
- NCT03034343
- Testing
- Mindfulness
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Universitat Jaume I
PTSD
Facilitating Transition to Recommended PTSD Treatment
Cognitive processing therapy (CPT) and prolonged exposure therapy (PE) were widely disseminated as recommended posttraumatic stress disorder (PTSD) treatments.
- Trial name
- NCT05165940
- Testing
- Treatment As Usual, New Health Services Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Office of Research and Development
Opioid Use Disorder
NavSTAR Implementation Effectiveness Trial Across a Health System
Patient Navigation (PN) interventions following hospitalization can improve outcomes for people with opioid use disorder treatment.
- Trial name
- Philly NavSTAR (NCT07262190)
- Testing
- NavSTAR (Philly adaptation)
- Where
- United States
- Volunteers
- 720 people
- Sponsor
- Friends Research Institute, Inc.
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