Clinical trials: Treatment as usual
Pregnancy, Anxiety
Childbirth Education Pilot Study
This study aims to investigate the effects of mindfulness training on prenatal maternal anxiety using a randomized controlled trial (RCT).
- Trial name
- NCT04327557
- Testing
- MBCP Childbirth Education Course, Non-MBCP Childbirth Education Course
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
HIV
WeMen! Improving Women's Access to Healthcare System Through Men's Inclusion
Background: More than two-thirds of people living with HIV live in Sub-Saharan Africa, where the HIV prevalence in the adult population (aged 15-49) is 3.9%.
- Trial name
- WEMEN (NCT04356157)
- Testing
- Behavioural change interventions
- Where
- 4 sites in Malawi
- Volunteers
- 450 people
- Sponsor
- University of Rome Tor Vergata
Infection
Far-UVC and Infections in Long-term Care Facilities
Background Elderly residents in long-term care (LTC) facilities are highly susceptible to infections, often leading to hospitalizations and placing significant strain on the healthcare sector.
- Trial name
- NCT07511881
- Testing
- Far-uvc (222 nm), Standard Care (Treatment as Usual)
- Where
- Denmark
- Volunteers
- 635 people, healthy volunteers welcome
- Sponsor
- Vejle Hospital
Multiple Sclerosis
Blood Flow Restriction for Upper Limb Rehabilitation in People With Multiple Sclerosis. A Randomized Controlled Trial (BFRT-EM)
Although the Blood Flow Restriction Training (BFRT) system has attracted the attention of health professionals, research on this tool in people with neurological pathology, particularly multiple sclerosis (MS), is very limited.
- Trial name
- BFRT-EM (NCT06795230)
- Testing
- Muscle strengthening (BFRT), Conventional physical therapy
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Rey Juan Carlos
Alcohol Use Disorder, Substance Use Disorders
Evaluating a One-Year Version of the Parent-Child Assistance Program
The proposed project seeks to achieve three objectives that will, collectively, evaluate the effectiveness of a one-year version of the Parent-Child Assistance Program (PCAP-1) -a model for a home visitation and case management…
- Conditions
- Alcohol Use Disorder, Substance Use Disorders, Alcohol Use Complicating Pregnancy, Unspecified Trimester, Drug Use Disorders
- Trial name
- PCAP-1 (NCT06163651)
- Testing
- Parent-Child Assistance Program - One-Year Version
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Oklahoma
Metastatic Prostate Cancer
TOward a comPrehensive Supportive Care Intervention for Older Men With Metastatic Prostate Cancer
TOPCOP3 is a pilot factorial RCT of geriatric assessment and management, remote symptom monitoring, both interventions or neither, accompanied by an embedded process evaluation.
- Trial name
- TOPCOP3 (NCT05582772)
- Testing
- GA+M Intervention, RSM intervention, GA+RSM intervention
- Where
- 3 sites in Canada
- Volunteers
- 168 people
- Sponsor
- University Health Network, Toronto
Anorexia Nervosa
Online Imaginal Exposure Therapy for Eating Disorders Trial
The goal of this clinical trial is to learn if an imaginal exposure intervention first conducted by Levinson and colleagues (2020) can produce similar promising results in individuals with anorexia on the waiting list of an NHS…
- Trial name
- NCT06818695
- Testing
- Imaginal Exposure for Anorexia Nervosa, Treatment as Usual (TAU)
- Where
- United Kingdom
- Volunteers
- 76 people
- Sponsor
- University College, London
Sickle Cell Disease (SCD)
Self-administered Acupressure in Patients With Sickle Cell Disease
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupressure analgesia in patients with sickle cell disease (SCD).
- Trial name
- NCT07875777
- Testing
- Verum Acupressure (using AcuWand)
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Cincinnati
Schizophrenia, Moral Status
Effects of Integrated Moral Reasoning Development Intervention for Management of Violence in Schizophrenia
Moral cognition is an important and multidimensional, but often overlooked, determinant of violence. Very few interventions have systematically examined the role of moral reasoning, anger management and problem-solving together…
- Conditions
- Schizophrenia, Moral Status, Violence
- Trial name
- NCT05207319
- Testing
- integrated Moral Reasoning Development Intervention (MRDI)
- Where
- Taiwan
- Volunteers
- 43 people
- Sponsor
- I-Shou University
Epilepsy
Behavioral and Educational Tools to Improve Epilepsy Care
The long-term goal of this research is to improve seizure control among patients with epilepsy, which has the potential to improve quality of life for thousands of people living with epilepsy and reduce health care utilization…
- Trial name
- NCT02646631
- Testing
- Usual Care, Management of Risks in Epilepsy (MORE), Telephone-based motivational interviewing (MORE+MI)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- NYU Langone Health
Insomnia
Follow-up of a Study Examining Sleep Management in United States Veterans
The first part of the pilot study, as detailed in Unique Protocol ID No. 27522, is a randomized clinical trial that compares the effects of a mind-body bridging program with a sleep hygiene program to improve sleep quality in…
- Trial name
- NCT00935337
- Testing
- Mind-Body Bridging Program, Sleep Hygiene
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Utah
Acute Respiratory Distress Syndrome
Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome
A randomized, concurrent controlled trial to assess if adding sigh breaths to usual invasive mechanical ventilation of victims of trauma who are at risk of developing ARDS will decrease the number of days they require invasive…
- Trial name
- SiVent (NCT02582957)
- Testing
- Sigh breaths
- Where
- 15 sites in United States
- Volunteers
- 524 people
- Sponsor
- University of Minnesota
Unipolar Depression
Bright Light Therapy for Depressed Geriatric Inpatients
Bright light therapy has been shown to be effective for the treatment of both seasonal and non-seasonal unipolar depression as well as bipolar depression, primarily in outpatients under the age of 60.
- Trial name
- NCT07002554
- Testing
- Bright light therapy, dim red light
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Sleep Disturbance, Sleep Deprivation
Behavioral Sleep Intervention in Urban Primary Care: Aim 3
Investigators will enroll up to 120 parent-child dyads from Children's Hospital of Philadelphia (CHOP) urban primary care clinics.
- Conditions
- Sleep Disturbance, Sleep Deprivation, Sleep
- Trial name
- NCT04473222
- Testing
- Sleep Well!, Sleep education
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- Children's Hospital of Philadelphia
Adolescent Behavior, Psychosocial Functioning
Intervention to Enhance Coping and Help-seeking Among Youth in Foster Care
This study will deploy a scalable secondary prevention program that leverages existing foster youth transition services to improve mental health functioning and service use before and after exiting foster care.
- Conditions
- Adolescent Behavior, Psychosocial Functioning, Coping Behavior, Help-Seeking Behavior
- Trial name
- NCT06019377
- Testing
- Stronger Youth Networks and Coping (SYNC)
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Portland State University
Cervical Cancer
Spatially Fractionated Radiation Therapy for Locally Advanced Cervical Cancer
This randomized clinical trial will evaluate whether adding spatially fractionated radiation therapy (SFRT) to definitive chemoradiotherapy improves outcomes in patients with locally advanced cervical cancer.
- Trial name
- SFRT-LACC (NCT07781475)
- Testing
- Spatially Fractionated Radiation Therapy, standard of care
- Where
- China
- Volunteers
- 126 people
- Sponsor
- The University of Hong Kong-Shenzhen Hospital
Poly Pharmacy, Frail Elderly
Applying a Multidisciplinary Intervention for Drug Adequacy in an Intermediate Care Hospital (AMIDA-ICH)
The goal of this clinical trial is to learn if a multi-professional (conducted by geriatricians, clinical pharmacists, nurses) medication revision, centered on patients' goals and characteristics, can improve treatment adequacy…
- Trial name
- AMIDA-ICH (NCT07015112)
- Testing
- Patient-centered multidisciplinary treatment review
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Parc Sanitari Pere Virgili
Chronic Pain
Redesign of Everyday Activities and Lifestyle With Occupational Therapy for Chronic Pain Patients
About 20-30% of the Danish population suffers from chronic non-malignant pain. Current evidence suggests that a bio-psychosocial treatment delivered by multidisciplinary teams is the most effective treatment of chronic…
- Trial name
- REVEAL(OT) (NCT03903900)
- Testing
- Lifestyle-oriented Occupational Therapy added to current treatment of chronic non-malignant pain
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Slagelse Hospital
Cardiovascular Disease, Periodontal Disease
Impact of Gum Infection on Heart Disease
The purpose of this study is to determine the effect of gum infection on parameters of cardio-vascular disease.
- Trial name
- NCT00093236
- Testing
- Early Periodontal Treatment, Usual Dental Hygiene
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Boston University
Acute Malnutrition in Childhood, Wasting
Integrated Research on Acute Malnutrition in Chad
The IRAM Chad impact evaluation will be based on a cluster randomized controlled trial to study the impact of the integrated and multisectoral services package (PASIM), aimed at reducing the incidence and prevalence of wasting…
- Trial name
- IRAM-CHAD (NCT04867694)
- Testing
- BCC, Preventive supplement, MNP
- Where
- Chad
- Volunteers
- 2,089 people
- Sponsor
- International Food Policy Research Institute
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