Clinical trials: Treatment as usual
Rheumatoid Arthritis, Depressive Symptoms
MBSR in Rheumatoid Arthritis Patients With Controlled Disease But Persistent Depressive Symptoms
Despite their efficacy at controlling joint inflammation, current treatments of rheumatoid arthritis (RA) leave up to 40% of patients into non-remission.
- Trial name
- PARIS-D (NCT03514355)
- Testing
- Mindfulness-Based Stress Reduction
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- Université de Sherbrooke
Opioid Use Disorder
Sex and Female Empowerment
This study will develop and initially evaluate Sex and Female Empowerment (SAFE), an intervention designed to increase acceptance of and adherence to contraceptive practices among opioid-agonist-maintained women of childbearing…
- Trial name
- SAFE (NCT02197715)
- Testing
- Computer-adaptive SAFE, Face-to-face SAFE, Usual Care
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Psychosis
The Effect of Psycho-education on Clinical Outcomes Among Patients With a First Episode Psychosis in Central Uganda
Background: Psychotic disorders which the investigators have operationally defined as any of schizophrenia or schizophrenia spectrum disorder, brief psychotic episode, or bipolar affective disorders are severe forms of mental…
- Trial name
- NCT04602585
- Testing
- Psycho-education
- Volunteers
- 80 people
- Sponsor
- Makerere University
Oral Mucositis Due to Radiation
A Sequential Cohort Study Exploring GELCLAIR in the Management of Oral Mucositis in Patients Receiving Radical Radiation for Head and Neck Cancer
The goal of this clinical trial is to learn if Gelclair lubricant gel can help manage Oral Mucositis (OM) among Oropharyngeal and Oral cavity cancer patients receiving radiation treatment.
- Trial name
- GOMS (NCT06897215)
- Testing
- Hyaluronic acid hydrogel
- Volunteers
- 48 people
- Sponsor
- Nova Scotia Health Authority
Commotio Cerebri, Mild Traumatic Brain Injury
Get Going After concussioN 2.0
The study tests the promising results of a previous study (GAIN 1.0) in a larger RCT (GAIN 2.0) which takes place in the municipalities of Central Denmark Region where citizens live their daily lives and whose health- and social…
- Trial name
- GAIN2 (NCT04798885)
- Testing
- GAIN 2.0
- Where
- Denmark
- Volunteers
- 310 people
- Sponsor
- University of Aarhus
Osteoarthritis
Nurse Led Follow-up After Total Knee Arthroplasty
The aim of this study is to determine the effect of nurse led follow-up following total knee arthroplasty in regard to physical function, health related quality of life and self-efficacy.
- Trial name
- NFTKA (NCT01771315)
- Testing
- Telephone follow-up
- Where
- Denmark
- Volunteers
- 117 people
- Sponsor
- University of Southern Denmark
HIV, Alcohol Use
Improving HIV and Alcohol-Related Outcomes Among HIV+ Persons in Clinic Settings
Alcohol use is increasingly recognized as a key factor in morbidity and mortality among HIV-positive individuals and represents an important public health concern, given its associations with medication non-adherence, increases…
- Conditions
- HIV, Alcohol Use, Medication Adherence
- Trial name
- PLUS (NCT02390908)
- Testing
- Immediate PLUS intervention, Wait-list PLUS intervention
- Where
- United States
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Hunter College of City University of New York
Prostate Cancer
Cost Talk: Discussing Cancer Care Costs
The purpose of this study is to investigate whether an encounter decision aid (used during a consultation) containing cost information about options, combined with clinician training about cost discussions and available financial…
- Trial name
- NCT04397016
- Testing
- Option Grid Decision Aid
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Washington University School of Medicine
Clinical Trial
AFRI Childhood Obesity Prevention Challenge Area
This study is a hybrid type 2 effectiveness-implementation trial of the Family Check-Up 4 Health (FCU4Health), an adapted version of the Family Check-Up, in pediatric primary care.
- Trial name
- NCT04469816
- Testing
- Family Check-Up 4 Health, Services as Usual
- Where
- 4 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Psychosis, Alcohol Use Disorder
Piloting of an Intervention to Reduce Problematic Alcohol Use in Early Phase Psychosis Patients
A focus of research for youth and Emerging Adults with early phase psychosis (EPP) has been cannabis use. However, this focus has led to overlooking the possible negative influence of another legal recreational drug, alcohol.
- Trial name
- NCT05365347
- Testing
- Cognitive Enhancement Therapy (CET)
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Nova Scotia Health Authority
Depression, Insomnia
Treatment of Insomnia and Depression in Elders (TIDE)
Insomnia and depression are two of the most prevalent mental health disorders and often co-occur. Health disparities in rural America and among African-Americans are well documented.
- Trial name
- TIDE (NCT01648049)
- Testing
- Integrated Cognitive Behavioral Therapy (CBT), Treatment as usual
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Alabama, Tuscaloosa
Self Harm, Suicidal Idealtion
Self Harm in Females of South Asian Family Origin
Aim of the study is to adapt and develop a culturally appropriate psychological intervention and to pilot test it's feasibility, and acceptability for the adult South Asian females presenting to general hospital emergency…
- Conditions
- Self Harm, Suicidal Idealtion, Hopelessness
- Trial name
- NCT00884078
- Testing
- Culturally adapted manualized problem solving training
- Where
- 3 sites in United Kingdom
- Volunteers
- 20 people
- Sponsor
- Lancashire Care NHS Foundation Trust
End-Stage Kidney Disease, Hemolysis
Fluid Distribution Timetable on Adherence to Fluid Restriction of Patients With End-Stage Renal Disease on Hemodialysis
Fluid restriction is necessary among patients with chronic kidney disease. However, treatment adherence remains a challenge. Hence, this study determined the effects of a fluid distribution timetable on adherence to fluid…
- Conditions
- End-Stage Kidney Disease, Hemolysis, Nursing
- Trial name
- NCT03582592
- Testing
- Fluid Distribution Timetable
- Volunteers
- 24 people
- Sponsor
- University of Santo Tomas Hospital, Philippines
Diabetes
Effectiveness of a Treat-to-target Clinic Led by a Nurse Consultants
The investigators hypothesize a diabetes nurse consultant led team with particular emphasis on compliance and attainment of treatment targets in Type 2 diabetic patients will achieve metabolic control, improve clinical outcomes…
- Trial name
- NCT01348867
- Testing
- Structured care led by a nurse consultant
- Where
- Hong Kong
- Volunteers
- 242 people
- Sponsor
- Asia Diabetes Foundation
Suicide, Suicide, Attempted
A Brief Intervention to Reduce Suicide Risk in Military Service Members and Veterans - Study 2 (SAFEMIL)
The investigators propose to test the efficacy of a brief, readily accessible, and personalized treatment called the Safety Planning for Military (SAFE MIL; Stanley and Brown, 2012).
- Trial name
- SAFEMIL (NCT01360736)
- Testing
- Safety Planning - Military (SAFE MIL)
- Where
- 2 sites in United States
- Volunteers
- 102 people
- Sponsor
- Henry M. Jackson Foundation for the Advancement of Military Medicine
Suicidal Ideation and Behavior
Stepped-Care for Suicidal Youth and Children
The goal of this RCT study is to test the efficacy of a stratified stepped-care (SSC) model in reducing suicidal thoughts and behaviors (STB) in children and adolescents. The main questions it aims to answer are: 1.
- Trial name
- SURE-CARE (NCT07321171)
- Testing
- IPC-A-SCI (Interpersonal Counseling for Suicide Crisis Intervention), IPT-A-SCI (Interpersonal Psychotherapy for Adolescents with Suicidal Crisis Intervention)
- Where
- Israel
- Volunteers
- 350 people
- Sponsor
- Shira Barzilay
Depression, Neurofeedback
Neurofeedback In Treatment Resistant Depression
The investigators evaluate the effects of neurofeedback as an augmentation treatment on depressive symptoms and functional recovery in patients with treatment-resistant depression (TRD).
- Trial name
- NCT04078438
- Testing
- neurofeedback augmentation, treatment as usual
- Where
- South Korea
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Yeungnam University Hospital
Post Traumatic Stress Disorder
Early Prevention of Post Traumatic Stress Disorder
Sunnybrook Health Sciences Centre is Canada's largest trauma centre, treating 1,100 patients annually. A traumatic experience can lead to post-traumatic stress disorder, which increases hospital stays, emergency visits and…
- Trial name
- NCT02004743
- Testing
- Intervention, Treatment as usual
- Where
- Canada
- Volunteers
- 99 people
- Sponsor
- Sunnybrook Health Sciences Centre
Depression, Postpartum, Anxiety
eMBC for Perinatal Depression and Anxiety
Depression and anxiety that occur around the time of pregnancy can adversely impact a person's health and well-being, and their child's health and development.
- Trial name
- eMBC (NCT04836585)
- Testing
- eMBC Intervention
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- Women's College Hospital
Verbal Auditory Hallucination, Psychotic Disorders
RELATE - Efficacy and Feasibility of a Cognitive Behavioural Module for Distressing Auditory Verbal Hallucinations
Auditory hallucinations (AH) are associated with distress and reduced functioning. Psychological interventions show some promising effects on psychopathology but have been less successful in reducing AH related distress, which…
- Conditions
- Verbal Auditory Hallucination, Psychotic Disorders, Psychosis, Schizophrenia
- Trial name
- RELATE (NCT04578314)
- Testing
- Relating Therapy, Treatment as usual
- Where
- 5 sites in Germany
- Volunteers
- 85 people
- Sponsor
- University of Hamburg-Eppendorf
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